DK2228440T3 - Varianter af beta-glucosidaser - Google Patents
Varianter af beta-glucosidaserInfo
- Publication number
- DK2228440T3 DK2228440T3 DK10165162.8T DK10165162T DK2228440T3 DK 2228440 T3 DK2228440 T3 DK 2228440T3 DK 10165162 T DK10165162 T DK 10165162T DK 2228440 T3 DK2228440 T3 DK 2228440T3
- Authority
- DK
- Denmark
- Prior art keywords
- beta
- glucosidases
- variants
- positions
- seq
- Prior art date
Links
- 102000005575 Cellulases Human genes 0.000 title abstract 2
- 108010084185 Cellulases Proteins 0.000 title abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 2
- 102000006995 beta-Glucosidase Human genes 0.000 abstract 2
- 108010047754 beta-Glucosidase Proteins 0.000 abstract 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
- C12N9/2445—Beta-glucosidase (3.2.1.21)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/02—Monosaccharides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/6895—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01021—Beta-glucosidase (3.2.1.21)
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Mycology (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Botany (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Medical Informatics (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Alternative & Traditional Medicine (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46776703P | 2003-05-02 | 2003-05-02 | |
| US52834203P | 2003-12-09 | 2003-12-09 | |
| EP04751000A EP1622921B1 (en) | 2003-05-02 | 2004-04-30 | Variants of beta-glucosidases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2228440T3 true DK2228440T3 (da) | 2013-01-02 |
Family
ID=33436742
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK10165162.8T DK2228440T3 (da) | 2003-05-02 | 2004-04-30 | Varianter af beta-glucosidaser |
| DK04751000.3T DK1622921T3 (da) | 2003-05-02 | 2004-04-30 | Varianter af beta-glucosidaser |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04751000.3T DK1622921T3 (da) | 2003-05-02 | 2004-04-30 | Varianter af beta-glucosidaser |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US7413888B2 (da) |
| EP (2) | EP1622921B1 (da) |
| AT (1) | ATE471370T1 (da) |
| DE (1) | DE602004027723D1 (da) |
| DK (2) | DK2228440T3 (da) |
| ES (2) | ES2393058T3 (da) |
| WO (1) | WO2004099228A2 (da) |
Families Citing this family (62)
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|---|---|---|---|---|
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| WO2009076655A2 (en) * | 2007-12-13 | 2009-06-18 | University Of Washington | Synthetic enzymes derived from computational design |
| JP2011507525A (ja) | 2007-12-19 | 2011-03-10 | ノボザイムス アクティーゼルスカブ | セルロース分解増強活性を有するポリペプチドとこれをコードするポリヌクレオチド |
| US8586828B2 (en) | 2008-03-06 | 2013-11-19 | Novozymes A/S | Polypeptides having beta-glucosidase activity and polynucleotides encoding same |
| US20110165635A1 (en) * | 2008-04-21 | 2011-07-07 | Chromatin, Inc. | Methods and materials for processing a feedstock |
| CN102482656A (zh) * | 2008-08-29 | 2012-05-30 | 埃欧金能源公司 | 具有提高的稳定性的经修饰的β-糖苷酶 |
| FR2935986B1 (fr) * | 2008-09-12 | 2012-11-23 | Inst Francais Du Petrole | Variants de beta-glucosidase a activite amelioree et leurs utilisations. |
| WO2010059413A2 (en) | 2008-11-20 | 2010-05-27 | Novozymes, Inc. | Polypeptides having amylolytic enhancing activity and polynucleotides encoding same |
| WO2010080527A1 (en) | 2008-12-19 | 2010-07-15 | Novozymes, Inc. | Methods for determining cellulolytic enhancing activity of a polypeptide |
| US8809033B2 (en) | 2008-12-19 | 2014-08-19 | Novozymes, Inc. | Methods for increasing hydrolysis of cellulosic material in the presence of cellobiose dehydrogenase |
| CA2752818A1 (en) * | 2009-02-26 | 2010-09-02 | Codexis, Inc. | Beta-glucosidase variant enzymes and related polynucleotides |
| US9012186B2 (en) | 2009-04-27 | 2015-04-21 | The Board Of Trustees Of The University Of Illinois | Hemicellulose-degrading enzymes |
| KR101183114B1 (ko) | 2009-05-08 | 2012-09-27 | 대한민국 | 백색부후균 유래 베타-글루코시다아제 유전자, 상기 유전자를 함유한 발현벡터, 상기 발현벡터로 형질전환된 형질전환체 및 상기 형질전환체의 제조방법 |
| CA2763836A1 (en) * | 2009-05-29 | 2010-12-02 | Iogen Energy Corporation | Novel beta-glucosidase enzymes |
| WO2010148148A2 (en) | 2009-06-16 | 2010-12-23 | Codexis, Inc. | β-GLUCOSIDASE VARIANTS |
| US8569581B2 (en) | 2009-09-17 | 2013-10-29 | Novozymes, Inc | Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same |
| WO2011057083A1 (en) | 2009-11-06 | 2011-05-12 | Novozymes, Inc. | Polypeptides having xylanase activity and polynucleotides encoding same |
| DK2496694T3 (da) | 2009-11-06 | 2017-06-06 | Novozymes Inc | Sammensætninger til saccharificering af cellulosematerial |
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| EP2504431A4 (en) * | 2009-11-25 | 2013-10-16 | Codexis Inc | RECOMBINANT BETA-GLUCOSIDASE VARIANTS OF THERMOASCUS AURIENTIACUS FOR THE PRODUCTION OF FERMENTABLE SUGARS FROM CELLULOSIC BIOMASS |
| PL2504017T3 (pl) * | 2009-11-25 | 2014-06-30 | Codexis Inc | Rekombinacyjne warianty beta-glukozydazy do wytwarzania rozpuszczalnych cukrów z biomasy celulozowej |
| CN111500474B (zh) | 2009-12-18 | 2023-10-03 | 诺维信股份有限公司 | 用于在木霉属的蛋白酶缺陷突变体中产生多肽的方法 |
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| CN102296053B (zh) * | 2010-06-25 | 2015-03-11 | 中国医学科学院药物研究所 | 一种7-木糖紫杉烷糖基水解酶、其基因的核苷酸序列及其应用 |
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| DK2622068T3 (da) | 2010-09-30 | 2016-10-17 | Novozymes Inc | Varianter af polypeptider med cellulolytisk forbedrende aktivitet og polynukleotider, der koder for dem |
| CN103237891B (zh) | 2010-09-30 | 2017-07-14 | 诺维信股份有限公司 | 具有纤维素分解增强活性的多肽变体及其编码多核苷酸 |
| DK2622069T3 (da) * | 2010-10-01 | 2016-02-22 | Novozymes Inc | Beta-glucosidasevarianter og polynukleotider, der koder for dem |
| WO2012068509A1 (en) | 2010-11-18 | 2012-05-24 | Novozymes, Inc. | Chimeric polypeptides having cellulolytic enhancing activity and polynucleotides encoding same |
| EP2649188A1 (en) | 2010-12-06 | 2013-10-16 | Novozymes North America, Inc. | Methods of hydrolyzing oligomers in hemicellulosic liquor |
| EP2703484A4 (en) * | 2011-03-24 | 2014-12-31 | Asahi Glass Co Ltd | TRANSFORMANT FROM YEAST OF ART SCHIZOSACCHAROMYCES, METHOD OF MANUFACTURING THEREOF, PROCESS FOR THE PREPARATION OF BETA-GLUCOSIDASE AND METHOD FOR THE DECOMPOSITION OF CELLULOSE |
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| EP2702162B1 (en) | 2011-04-29 | 2020-02-26 | Novozymes, Inc. | Methods for enhancing the degradation or conversion of cellulosic material |
| BR112014003444A2 (pt) | 2011-08-19 | 2017-03-14 | Novozymes Inc | célula hospedeira recombinante, e, método para produzir um ácido c4-dicarboxílico |
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| CN106062276B (zh) | 2014-03-05 | 2019-06-11 | 诺维信公司 | 用于将材料功能化并且进行连接的组合物和方法 |
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| CN106062270A (zh) | 2014-03-05 | 2016-10-26 | 诺维信公司 | 使用木葡聚糖内糖基转移酶改进非纤维素纺织材料的性质的组合物和方法 |
| US10123535B2 (en) | 2014-03-05 | 2018-11-13 | Novozymes A/S | Compositions and methods for improving post-harvest properties of agricultural crops |
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| EP3227438B1 (en) | 2014-12-02 | 2024-03-27 | Novozymes A/S | Laccase variants and polynucleotides encoding same |
| CN104450651B (zh) * | 2014-12-09 | 2017-08-15 | 青岛蔚蓝生物集团有限公司 | 一种β‑葡萄糖苷酶突变体及其应用 |
| JP6850130B2 (ja) * | 2015-01-20 | 2021-03-31 | サントリーホールディングス株式会社 | モグロシドの調製方法 |
| HUE066391T2 (hu) | 2015-04-10 | 2024-07-28 | Comet Biorefining Inc | Eljárások és összetételek a cellulózos biomassza kezelésére és így elõállított termékek |
| US20180171271A1 (en) * | 2015-06-30 | 2018-06-21 | Novozymes A/S | Laundry detergent composition, method for washing and use of composition |
| DK3387139T3 (da) * | 2015-12-10 | 2020-07-20 | Dsm Ip Assets Bv | Beta-glucosidase og anvendelser deraf |
| CN105567662B (zh) * | 2016-01-28 | 2018-09-07 | 中国农业科学院饲料研究所 | 一种嗜热β-葡萄糖苷酶突变体-M36N及其编码基因和应用 |
| MX2020011986A (es) | 2018-05-10 | 2021-01-29 | Comet Biorefining Inc | Composiciones que comprenden glucosa y hemicelulosa y su uso. |
| CN114072012B (zh) | 2019-05-10 | 2025-03-18 | 彗星生物炼制公司 | 用于生产阿拉伯木聚糖组合物的材料和方法 |
| CN116334044B (zh) * | 2021-12-22 | 2025-09-23 | 湖南中烟工业有限责任公司 | 烟草烟碱积累相关基因NtBGLU1、蛋白及其应用 |
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-
2004
- 2004-04-30 DK DK10165162.8T patent/DK2228440T3/da active
- 2004-04-30 DK DK04751000.3T patent/DK1622921T3/da active
- 2004-04-30 ES ES10165162T patent/ES2393058T3/es not_active Expired - Lifetime
- 2004-04-30 EP EP04751000A patent/EP1622921B1/en not_active Expired - Lifetime
- 2004-04-30 AT AT04751000T patent/ATE471370T1/de not_active IP Right Cessation
- 2004-04-30 WO PCT/US2004/013401 patent/WO2004099228A2/en not_active Ceased
- 2004-04-30 EP EP10165162A patent/EP2228440B1/en not_active Expired - Lifetime
- 2004-04-30 DE DE602004027723T patent/DE602004027723D1/de not_active Expired - Lifetime
- 2004-04-30 ES ES04751000T patent/ES2347658T3/es not_active Expired - Lifetime
- 2004-04-30 US US10/836,063 patent/US7413888B2/en not_active Expired - Fee Related
-
2008
- 2008-06-26 US US12/147,333 patent/US7638616B2/en not_active Expired - Fee Related
-
2009
- 2009-12-16 US US12/639,642 patent/US8852913B2/en not_active Expired - Fee Related
-
2014
- 2014-10-06 US US14/507,539 patent/US9080165B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004099228A2 (en) | 2004-11-18 |
| US8852913B2 (en) | 2014-10-07 |
| US7638616B2 (en) | 2009-12-29 |
| EP2228440B1 (en) | 2012-08-22 |
| US9080165B2 (en) | 2015-07-14 |
| EP2228440A1 (en) | 2010-09-15 |
| DK1622921T3 (da) | 2010-09-13 |
| US20090053765A1 (en) | 2009-02-26 |
| DE602004027723D1 (de) | 2010-07-29 |
| US20150099280A1 (en) | 2015-04-09 |
| ATE471370T1 (de) | 2010-07-15 |
| EP1622921A2 (en) | 2006-02-08 |
| US7413888B2 (en) | 2008-08-19 |
| WO2004099228A3 (en) | 2005-12-29 |
| US20040253702A1 (en) | 2004-12-16 |
| EP1622921B1 (en) | 2010-06-16 |
| US20100099146A1 (en) | 2010-04-22 |
| ES2347658T3 (es) | 2010-11-03 |
| ES2393058T3 (es) | 2012-12-18 |
| EP1622921A4 (en) | 2006-12-27 |
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