|
US6403597B1
(en)
|
1997-10-28 |
2002-06-11 |
Vivus, Inc. |
Administration of phosphodiesterase inhibitors for the treatment of premature ejaculation
|
|
US6548490B1
(en)
|
1997-10-28 |
2003-04-15 |
Vivus, Inc. |
Transmucosal administration of phosphodiesterase inhibitors for the treatment of erectile dysfunction
|
|
WO2001019818A1
(en)
*
|
1999-09-14 |
2001-03-22 |
Byk Gulden Lomberg Chemische Fabrik Gmbh |
Phthalazinone derivatives as pd3/4 inhibitors
|
|
SK7232002A3
(en)
|
1999-10-25 |
2002-09-10 |
Byk Gulden Lomberg Chem Fab |
Tetrahydrothiopyranphthalazinone derivatives as pde4 inhibitors
|
|
AU781503B2
(en)
|
1999-10-25 |
2005-05-26 |
Altana Pharma Ag |
Phthalazinone derivatives as PDE 4 inhibitors
|
|
PT2348032E
(pt)
|
2000-08-05 |
2015-10-14 |
Glaxo Group Ltd |
Éster s-fluorometílico do ácido 6.alfa.,9.alfa.-difluoro- 17.alfa.-'(2-furanilcarboxil)oxi]-11.beta.-hidroxi-16.alfa.- metil-3-oxo-androsta-1,4-dieno-17-carbotióico como um agente anti-inflamatório
|
|
GB0103630D0
(en)
|
2001-02-14 |
2001-03-28 |
Glaxo Group Ltd |
Chemical compounds
|
|
KR20030074817A
(ko)
|
2001-02-15 |
2003-09-19 |
알타나 파마 아게 |
Pde4 억제제로서의 프탈라지논-피페리디노-유도체
|
|
EP1370521B1
(en)
|
2001-03-22 |
2007-12-19 |
Glaxo Group Limited |
Formanilide derivatives as beta2-adrenoreceptor agonists
|
|
BR0209149A
(pt)
|
2001-04-25 |
2004-07-13 |
Altana Pharma Ag |
Ftalazinonas
|
|
EA200301101A1
(ru)
*
|
2001-04-25 |
2004-04-29 |
Алтана Фарма Аг |
Производные пиперазина и их применение в качестве ингибиторов pde4
|
|
CA2445839A1
(en)
|
2001-04-30 |
2002-11-07 |
Glaxo Group Limited |
Anti-inflammatory 17.beta.-carbothioate ester derivatives of androstane with a cyclic ester group in position 17.alpha
|
|
WO2003008396A1
(en)
*
|
2001-07-16 |
2003-01-30 |
Nikken Chemicals Co., Ltd. |
Optically active oxazine derivative
|
|
US20030073711A1
(en)
*
|
2001-08-23 |
2003-04-17 |
Whitehead Clark M. |
Methods for treatment of scleroderma
|
|
US6479493B1
(en)
|
2001-08-23 |
2002-11-12 |
Cell Pathways, Inc. |
Methods for treatment of type I diabetes
|
|
AU2002326026B2
(en)
|
2001-09-14 |
2005-04-28 |
Glaxo Group Limited |
Phenethanolamine derivatives for treatment of respiratory diseases
|
|
GB0201677D0
(en)
|
2002-01-25 |
2002-03-13 |
Glaxo Group Ltd |
Medicament dispenser
|
|
ES2298511T3
(es)
|
2002-04-25 |
2008-05-16 |
Glaxo Group Limited |
Derivados de fenetanolamina.
|
|
GB0217225D0
(en)
|
2002-07-25 |
2002-09-04 |
Glaxo Group Ltd |
Medicinal compounds
|
|
WO2004018450A1
(en)
*
|
2002-08-10 |
2004-03-04 |
Altana Pharma Ag |
Piperidine-n-oxide-derivatives
|
|
CN1671695A
(zh)
*
|
2002-08-10 |
2005-09-21 |
奥坦纳医药公司 |
用作pde4抑制剂的吡咯烷二酮取代的哌啶-2,3-二氮杂萘酮化合物
|
|
US20060167001A1
(en)
*
|
2002-08-10 |
2006-07-27 |
Sterk Jan G |
Pyridazinone-derivatives as pde4 inhibitors
|
|
AU2003255376A1
(en)
*
|
2002-08-10 |
2004-03-11 |
Altana Pharma Ag |
Piperidine-derivatives as pde4 inhibitors
|
|
CA2503588A1
(en)
|
2002-10-28 |
2004-05-06 |
Glaxo Group Limited |
Phenethanolamine derivative for the treatment of respiratory diseases
|
|
PE20040950A1
(es)
|
2003-02-14 |
2005-01-01 |
Theravance Inc |
DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
|
|
GB0303396D0
(en)
|
2003-02-14 |
2003-03-19 |
Glaxo Group Ltd |
Medicinal compounds
|
|
GB0316290D0
(en)
|
2003-07-11 |
2003-08-13 |
Glaxo Group Ltd |
Novel compounds
|
|
GB0317374D0
(en)
|
2003-07-24 |
2003-08-27 |
Glaxo Group Ltd |
Medicament dispenser
|
|
GB0329182D0
(en)
|
2003-12-17 |
2004-01-21 |
Glaxo Group Ltd |
Chemical compounds
|
|
WO2005075437A1
(en)
*
|
2004-02-04 |
2005-08-18 |
Altana Pharma Ag |
Pyridazinone derivatives and their use as pde4 inhibitors
|
|
AU2005210042B2
(en)
*
|
2004-02-04 |
2011-04-21 |
Takeda Gmbh |
2-(piperidin-4-yl) -4, 5-dihydro-2H-pyridazin-3-one derivatives as PDE4 inhibitors
|
|
TWI341836B
(en)
|
2004-03-11 |
2011-05-11 |
Theravance Inc |
Biphenyl compounds useful as muscarinic receptor antagonists
|
|
AR049384A1
(es)
|
2004-05-24 |
2006-07-26 |
Glaxo Group Ltd |
Derivados de purina
|
|
TWI307630B
(en)
|
2004-07-01 |
2009-03-21 |
Glaxo Group Ltd |
Immunoglobulins
|
|
GB0418045D0
(en)
|
2004-08-12 |
2004-09-15 |
Glaxo Group Ltd |
Compounds
|
|
JP2008510015A
(ja)
|
2004-08-16 |
2008-04-03 |
セラヴァンス, インコーポレーテッド |
β2アドレナリン作用性レセプターアゴニスト活性およびムスカリン性レセプターアンタゴニスト活性を有する化合物
|
|
US7579335B2
(en)
|
2005-01-10 |
2009-08-25 |
Glaxo Group Limited |
Androstane 17α-carbonate derivatives for use in the treatment of allergic and inflammatory conditions
|
|
TWI389690B
(zh)
|
2005-03-25 |
2013-03-21 |
Glaxo Group Ltd |
新穎化合物(一)
|
|
GB0514809D0
(en)
|
2005-07-19 |
2005-08-24 |
Glaxo Group Ltd |
Compounds
|
|
TW200730498A
(en)
|
2005-12-20 |
2007-08-16 |
Glaxo Group Ltd |
Compounds
|
|
EA200801997A1
(ru)
|
2006-04-20 |
2009-04-28 |
Глаксо Груп Лимитед |
Новые соединения
|
|
GB0611587D0
(en)
|
2006-06-12 |
2006-07-19 |
Glaxo Group Ltd |
Novel compounds
|
|
MY148634A
(en)
|
2006-07-25 |
2013-05-15 |
Cephalon Inc |
Pyridazinone derivatives
|
|
JPWO2008111631A1
(ja)
*
|
2007-03-14 |
2010-06-24 |
日本新薬株式会社 |
α−メチルベンジルアミン塩の製法
|
|
AR065804A1
(es)
|
2007-03-23 |
2009-07-01 |
Smithkline Beecham Corp |
Compuesto de indol carboxamida, composicion farmaceutica que lo comprende y uso de dicho compuesto para preparar un medicamento
|
|
US7943658B2
(en)
|
2007-07-23 |
2011-05-17 |
Bristol-Myers Squibb Company |
Indole indane amide compounds useful as CB2 agonists and method
|
|
AU2009325091A1
(en)
|
2008-05-23 |
2010-06-17 |
Panmira Pharmaceuticals, Llc |
5-lipoxygenase-activating protein inhibitor
|
|
US8163743B2
(en)
|
2008-06-05 |
2012-04-24 |
GlaxoGroupLimited |
4-carboxamide indazole derivatives useful as inhibitors of PI3-kinases
|
|
MX2010013191A
(es)
|
2008-06-24 |
2010-12-17 |
Hoffmann La Roche |
Nuevas piridin-3-onas y piridazin-3-onas sustituidas.
|
|
RU2507202C2
(ru)
|
2008-07-02 |
2014-02-20 |
Ф.Хоффманн-Ля Рош Аг |
Новые фенилпиразиноны в качестве ингибиторов киназы
|
|
WO2010094643A1
(en)
|
2009-02-17 |
2010-08-26 |
Glaxo Group Limited |
Quinoline derivatives and their uses for rhinitis and urticaria
|
|
EP2406255B1
(en)
|
2009-03-09 |
2015-04-29 |
Glaxo Group Limited |
4-oxadiazol-2-yl-indazoles as inhibitors of pi3 kinases
|
|
EP2406249A1
(en)
|
2009-03-10 |
2012-01-18 |
Glaxo Group Limited |
Indole derivatives as ikk2 inhibitors
|
|
US20120058984A1
(en)
|
2009-03-17 |
2012-03-08 |
Catherine Mary Alder |
Pyrimidine derivatives used as itk inhibitors
|
|
WO2010107955A2
(en)
|
2009-03-19 |
2010-09-23 |
Merck Sharp & Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF BTB AND CNC HOMOLOGY 1, BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR 1 (BACH 1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) SEQUENCE LISTING
|
|
WO2010107952A2
(en)
|
2009-03-19 |
2010-09-23 |
Merck Sharp & Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF CONNECTIVE TISSUE GROWTH FACTOR (CTGF) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
|
US20120029054A1
(en)
|
2009-03-19 |
2012-02-02 |
Merck Sharp & Dohme Corp. |
RNA Interference Mediated Inhibition of GATA Binding Protein 3 (GATA3) Gene Expression Using Short Intefering Nucleic Acid (siNA)
|
|
US20120035247A1
(en)
|
2009-03-19 |
2012-02-09 |
Merck Sharp & Dohme Corp. |
RNA Interference Mediated Inhibition of Signal Transducer and Activator of Transcription 6 (STAT6) Gene Expression Using Short Interfering Nucleic Acid (siNA)
|
|
MX2011010072A
(es)
|
2009-03-27 |
2011-10-06 |
Merck Sharp & Dohme |
Inhibicion mediada por interferencia de acido ribonucleico de la expresion del gen de la molecula de adhesion intercelular 1 usando acido nucleico corto de interferencia.
|
|
JP2012521762A
(ja)
|
2009-03-27 |
2012-09-20 |
メルク・シャープ・エンド・ドーム・コーポレイション |
低分子干渉核酸(siNA)を用いた神経成長因子β鎖(NGFβ)遺伝子発現のRNA干渉媒介性阻害
|
|
EP2411516A1
(en)
|
2009-03-27 |
2012-02-01 |
Merck Sharp&Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF APOPTOSIS SIGNAL-REGULATING KINASE 1 (ASK1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
|
US20120022142A1
(en)
|
2009-03-27 |
2012-01-26 |
Merck Sharp & Dohme Corp. |
RNA Interference Mediated Inhibition of Signal Transducer and Activator of Transcription 1 (STAT1) Gene Expression Using Short Interfering Nucleic Acid (siNA)
|
|
EP2411520A2
(en)
|
2009-03-27 |
2012-02-01 |
Merck Sharp&Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF THE THYMIC STROMAL LYMPHOPOIETIN (TSLP) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
|
JP2012524755A
(ja)
|
2009-04-24 |
2012-10-18 |
グラクソ グループ リミテッド |
Cracチャネル阻害剤としてのn−ピラゾリルカルボキサミド
|
|
JP2012524754A
(ja)
|
2009-04-24 |
2012-10-18 |
グラクソ グループ リミテッド |
Cracチャネル阻害剤としてのピラゾールおよびトリアゾ−ルカルボキサミド
|
|
JP5570589B2
(ja)
|
2009-04-30 |
2014-08-13 |
グラクソ グループ リミテッド |
Pi3キナーゼ阻害剤としてのオキサゾール置換インダゾール
|
|
ES2557553T3
(es)
|
2009-07-15 |
2016-01-27 |
Theravance Biopharma R&D Ip, Llc |
Forma de base libre cristalina de un compuesto de bifenilo
|
|
WO2011067366A1
(en)
|
2009-12-03 |
2011-06-09 |
Glaxo Group Limited |
Indazole derivatives as pi 3 - kinase inhibitors
|
|
JP2013512879A
(ja)
|
2009-12-03 |
2013-04-18 |
グラクソ グループ リミテッド |
Pi3キナーゼの阻害剤としてのベンズピラゾール誘導体
|
|
EP2507226A1
(en)
|
2009-12-03 |
2012-10-10 |
Glaxo Group Limited |
Novel compounds
|
|
WO2011084316A2
(en)
|
2009-12-16 |
2011-07-14 |
3M Innovative Properties Company |
Formulations and methods for controlling mdi particle size delivery
|
|
WO2011110575A1
(en)
|
2010-03-11 |
2011-09-15 |
Glaxo Group Limited |
Derivatives of 2-[2-(benzo- or pyrido-) thiazolylamino]-6-aminopyridine, useful in the treatment of respiratoric, allergic or inflammatory diseases
|
|
GB201007203D0
(en)
|
2010-04-29 |
2010-06-16 |
Glaxo Group Ltd |
Novel compounds
|
|
WO2012032067A1
(en)
|
2010-09-08 |
2012-03-15 |
Glaxo Group Limited |
Polymorphs and salts of n- [5- [4- (5- { [(2r,6s) -2, 6 - dimethyl - 4 -morpholinyl] methyl} - 1, 3 - oxazol - 2 - yl) - 1h- inda zol-6-yl] -2- (methyloxy) - 3 - pyridinyl] methanesulfonamide
|
|
US9326987B2
(en)
|
2010-09-08 |
2016-05-03 |
Glaxo Group Limited |
Indazole derivatives for use in the treatment of influenza virus infection
|
|
WO2012035055A1
(en)
|
2010-09-17 |
2012-03-22 |
Glaxo Group Limited |
Novel compounds
|
|
JP2013544794A
(ja)
|
2010-10-21 |
2013-12-19 |
グラクソ グループ リミテッド |
アレルギー性障害、炎症性障害及び免疫障害に作用するピラゾール化合物
|
|
EP2630126B1
(en)
|
2010-10-21 |
2015-01-07 |
Glaxo Group Limited |
Pyrazole compounds acting against allergic, immune and inflammatory conditions
|
|
GB201018124D0
(en)
|
2010-10-27 |
2010-12-08 |
Glaxo Group Ltd |
Polymorphs and salts
|
|
GB201104153D0
(en)
|
2011-03-11 |
2011-04-27 |
Glaxo Group Ltd |
Novel compounds
|
|
EP2683716A1
(en)
|
2011-03-11 |
2014-01-15 |
Glaxo Group Limited |
Pyrido[3,4-b]pyrazine derivatives as syk inhibitors
|
|
ES2564882T3
(es)
*
|
2011-06-17 |
2016-03-29 |
Takeda Gmbh |
Nuevos derivados de ftalacinonapirrolopirimidincarboxamida
|
|
US20150119399A1
(en)
|
2012-01-10 |
2015-04-30 |
President And Fellows Of Harvard College |
Beta-cell replication promoting compounds and methods of their use
|
|
BR112015023328A2
(pt)
|
2013-03-13 |
2017-07-18 |
Flatley Discovery Lab |
compostos de piridazinona e métodos para o tratamento de fibrose cística
|
|
WO2014159776A1
(en)
*
|
2013-03-14 |
2014-10-02 |
Cephalon, Inc. |
Solid state forms of 6-[4-[3-(r)-2-methylpyrrolidine-1-yl)-propoxy]phenyl]2h-pyridazine-3-one hydrochloride
|
|
KR20160062178A
(ko)
|
2013-10-17 |
2016-06-01 |
글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 |
호흡기 질병의 치료를 위한 pi3k 억제제
|
|
AU2014336250A1
(en)
|
2013-10-17 |
2016-04-14 |
Glaxosmithkline Intellectual Property Development Limited |
PI3K inhibitor for treatment of respiratory disease
|
|
EP3142694A2
(en)
|
2014-05-12 |
2017-03-22 |
Glaxosmithkline Intellectual Property (No. 2) Limited |
Pharmaceutical compositions comprising danirixin for treating infectious diseases
|
|
JP6506836B2
(ja)
|
2014-08-14 |
2019-04-24 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
B型肝炎ウイルス感染症の処置および予防のための新規ピリダゾンおよびトリアジノン
|
|
CN104478809B
(zh)
*
|
2014-11-14 |
2016-08-17 |
成都新恒创药业有限公司 |
一种左西孟旦杂质及其制备和检测方法
|
|
GB201602527D0
(en)
|
2016-02-12 |
2016-03-30 |
Glaxosmithkline Ip Dev Ltd |
Chemical compounds
|
|
JP2019524792A
(ja)
|
2016-08-08 |
2019-09-05 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited |
化合物
|
|
WO2018094392A1
(en)
|
2016-11-21 |
2018-05-24 |
Lupin Inc. |
Medicament dispenser
|
|
GB201706102D0
(en)
|
2017-04-18 |
2017-05-31 |
Glaxosmithkline Ip Dev Ltd |
Chemical compounds
|
|
GB201712081D0
(en)
|
2017-07-27 |
2017-09-13 |
Glaxosmithkline Ip Dev Ltd |
Chemical compounds
|
|
WO2019195711A1
(en)
|
2018-04-06 |
2019-10-10 |
Lupin Inc. |
Medicament dispenser
|
|
WO2020058823A1
(en)
|
2018-09-17 |
2020-03-26 |
Lupin, Inc. |
Dose indicator assembly for a medicament dispenser
|
|
US20230120431A1
(en)
|
2020-03-25 |
2023-04-20 |
Lupin Inc. |
Multi-Carrier Medicament Dispensers
|
|
EP4185997A1
(en)
|
2020-07-23 |
2023-05-31 |
Lupin Inc. |
Dose counter assemblies for medicament dispensers
|