DK0948541T3 - Analoge af PTHrP - Google Patents

Analoge af PTHrP

Info

Publication number: DK0948541T3
Authority: DK; Denmark
Prior art keywords: pthrp; analogs; parathyroid hormone; pth; acc
Prior art date: 1997-01-07

Application number

DK97951595T

Other languages

English (en)

Inventor

Zheng Xin Dong

Original Assignee

Sod Conseils Rech Applic

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-01-07

Filing date

1997-12-08

Publication date

2006-07-17

1997-01-07 Priority claimed from US08/779,768 external-priority patent/US5969095A/en

1997-12-08 Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic

2006-07-17 Application granted granted Critical

2006-07-17 Publication of DK0948541T3 publication Critical patent/DK0948541T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Endocrinology (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Physical Education & Sports Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Molecular Biology (AREA)
Chemical Kinetics & Catalysis (AREA)
Genetics & Genomics (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Diabetes (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

DK97951595T 1997-01-07 1997-12-08 Analoge af PTHrP DK0948541T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/779,768 US5969095A (en)	1995-07-13	1997-01-07	Analogs of parathyroid hormone
US08/813,534 US5955574A (en)	1995-07-13	1997-03-07	Analogs of parathyroid hormone

Publications (1)

Publication Number	Publication Date
DK0948541T3 true DK0948541T3 (da)	2006-07-17

Family

ID=27119618

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK05026436.5T DK1645566T3 (da)	1997-01-07	1997-12-08	Parathyroidhormonanaloger
DK97951595T DK0948541T3 (da)	1997-01-07	1997-12-08	Analoge af PTHrP

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DK05026436.5T DK1645566T3 (da)	1997-01-07	1997-12-08	Parathyroidhormonanaloger

Country Status (24)

Country	Link
US (1)	US5955574A (da)
EP (3)	EP1645566B1 (da)
JP (1)	JP3963482B2 (da)
KR (2)	KR100497709B1 (da)
CN (1)	CN1137898C (da)
AR (3)	AR011517A1 (da)
AT (2)	ATE471342T1 (da)
AU (1)	AU741584B2 (da)
BR (1)	BR9714200A (da)
CA (1)	CA2276614C (da)
CZ (2)	CZ301497B6 (da)
DE (2)	DE69735603T2 (da)
DK (2)	DK1645566T3 (da)
ES (2)	ES2258286T3 (da)
HK (1)	HK1026215A1 (da)
HU (1)	HUP9904596A3 (da)
IL (1)	IL130794A0 (da)
NO (1)	NO993341L (da)
NZ (1)	NZ336610A (da)
PL (1)	PL191898B1 (da)
PT (2)	PT1645566E (da)
RU (1)	RU2198182C2 (da)
SI (2)	SI0948541T1 (da)
WO (1)	WO1998030590A2 (da)

Families Citing this family (29)

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US7410948B2 (en) *	1995-07-13	2008-08-12	Societe De Conseils De Recherches Et D'applications Scientifiques, Sas	Analogs of parathyroid hormone
US6544949B1 (en) *	1995-07-13	2003-04-08	Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S.	Analogs of parathyroid hormone
JP2002509854A (ja)	1997-09-09	2002-04-02	エフ．ホフマン−ラロシュアーゲー	ＰＴＨｒＰ類似体を使用する骨折治癒
HUP0300891A2 (hu) *	1998-05-05	2003-07-28	Beth Israel Deaconess Medical Center, Inc.	PTH2 receptor szelektív vegyületek és alkalmazásuk gyógyszerkészítmények előállÍtására
DE69941708D1 (de) *	1998-07-20	2010-01-07	Ipsen Pharma	Pacap-peptidanaloga
US6660843B1 (en) †	1998-10-23	2003-12-09	Amgen Inc.	Modified peptides as therapeutic agents
WO2001060862A1 (en)	2000-02-18	2001-08-23	Dabur Research Foundation	Vasoactive intestinal peptide analogs
US6756480B2 (en) *	2000-04-27	2004-06-29	Amgen Inc.	Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein
US20050124537A1 (en) *	2000-04-27	2005-06-09	Amgen Inc.	Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein
MXPA03011027A (es)	2001-06-01	2004-03-19	Novartis Ag	Administracion oral de hormona paratiroides y calcitonina.
CA2454275C (en)	2001-07-23	2012-10-23	The General Hospital Corporation	Conformationally constrained parathyroid hormone (pth) analogs
KR20060056975A (ko) *	2003-08-06	2006-05-25	로디아 인코포레이티드	뼈 성장 촉진방법
AU2006315132A1 (en)	2005-11-10	2007-05-24	Board Of Control Of Michigan Technological University	Black bear parathyroid hormone and methods of using black bear parathyroid hormone
US7803770B2 (en)	2006-10-03	2010-09-28	Radius Health, Inc.	Method of treating osteoporosis comprising administration of PTHrP analog
USRE49444E1 (en)	2006-10-03	2023-03-07	Radius Health, Inc.	Method of treating osteoporosis comprising administration of PTHrP analog
CN102274492B (zh) *	2006-10-03	2014-11-26	半径健康公司	骨合成代谢蛋白质的药物递送方法
WO2008048784A1 (en) *	2006-10-13	2008-04-24	Eli Lilly And Company	Pegylated pth as pth receptor modulators and uses thereof
EP2187902B1 (en)	2007-08-01	2013-04-17	The General Hospital Corporation	Screening methods using g-protein coupled receptors and related compositions
US8563513B2 (en)	2009-03-27	2013-10-22	Van Andel Research Institute	Parathyroid hormone peptides and parathyroid hormone-related protein peptides and methods of use
EP2509996A1 (en)	2009-12-07	2012-10-17	Michigan Technological University	Black bear parathyroid hormone and methods of using black bear parathyroid hormone
MX342898B (es)	2010-05-12	2016-10-18	Radius Health Inc *	Regimen terapéutico de la sal de diclorhidrato del (r) -6-(2-(etil (4-2(etilamino) etil) bencil) amino)-4-metoxifenil)-5, 6,7,8-tetrahidronaftaleno-2-ol.
US9492508B2 (en)	2010-05-13	2016-11-15	The General Hospital Corporation	Parathyroid hormone analogs and uses thereof
JP5965909B2 (ja)	2010-09-28	2016-08-10	ラジウスヘルス，インコーポレイテッド	選択的アンドロゲン受容体モジュレーター
SG11201708858WA (en)	2015-04-29	2017-11-29	Radius Pharmaceuticals Inc	Methods of treating cancer
CN108025042A (zh) *	2015-07-06	2018-05-11	董正欣	PTHrP类似物的新型制剂
SG11201811225RA (en)	2016-06-22	2019-01-30	Radius Health Inc	Ar+ breast cancer treatment methods
JP7481115B2 (ja)	2017-01-05	2024-05-10	ラジウスファーマシューティカルズ，インコーポレイテッド	Ｒａｄ１９０１－２ｈｃｌの多形性形態
US10996208B2 (en)	2017-04-28	2021-05-04	Radius Health, Inc.	Abaloparatide formulations and methods of testing, storing, modifying, and using same
AU2019297421B2 (en)	2018-07-04	2024-08-29	Radius Pharmaceuticals, Inc.	Polymorphic forms of RAD 1901-2HCL

Family Cites Families (18)

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Publication number	Priority date	Publication date	Assignee	Title
US3773919A (en)	1969-10-23	1973-11-20	Du Pont	Polylactide-drug mixtures
IE52535B1 (en)	1981-02-16	1987-12-09	Ici Plc	Continuous release pharmaceutical compositions
FR2550204B1 (fr) *	1983-08-05	1987-11-13	Toyo Jozo Kk	Derives peptidiques de (nle8,nle1b, tyr34)-h-pth
EP0293158A3 (en) *	1987-05-26	1990-05-09	Merck & Co. Inc.	Parathyroid hormone antagonists
EP0411096A1 (de) *	1989-02-23	1991-02-06	Gesellschaft für Biotechnologische Forschung mbH (GBF)	Pth-varianten kodierende dna-sequenzen, pth-varianten, expressionsvektor, bakterieller wirt, verwendung und therapeutische zusammensetzung
CA2040264A1 (en) *	1990-04-12	1991-10-13	Tatsuhiko Kanmera	Parathyroid hormone antagonists
JPH0532696A (ja) *	1990-09-28	1993-02-09	Takeda Chem Ind Ltd	副甲状腺ホルモン誘導体
WO1993006846A1 (en) *	1991-10-10	1993-04-15	Pang Peter K T	Parathyroid hormone analogues and use in osteoporosis treatment
US5434246A (en) *	1992-03-19	1995-07-18	Takeda Chemical Industries, Ltd.	Parathyroid hormone derivatives
CA2098639A1 (en) *	1992-06-19	1993-12-20	K. Anne Kronis	Bone stimulating, non-vasoactive parathyroid hormone variants
US5821225A (en) *	1992-07-14	1998-10-13	Syntex (U.S.A.) Inc.	Method for the treatment of corticosteroid induced osteopenia comprising administration of modified PTH or PTHrp
US5589452A (en) *	1992-07-14	1996-12-31	Syntex (U.S.A.) Inc.	Analogs of parathyroid hormone and parathyroid hormone related peptide: synthesis and use for the treatment of osteoporosis
AU672790B2 (en) *	1992-07-15	1996-10-17	Novartis Ag	Variants of parathyroid hormone and its fragments
NZ261250A (en)	1993-01-06	1997-08-22	Kinerton Ltd	Ionic conjugates of polypeptides
CN1070500C (zh) *	1993-07-13	2001-09-05	森德克斯(美国)股份有限公司	甲状旁腺激素类似物和甲状旁腺激素相关肽：合成和治疗骨质疏松症的用途
WO1996019246A1 (en) *	1994-12-19	1996-06-27	Beth Israel Hospital Association	Continuous low-dose administration of parathyroid hormone or its agonist
CA2178894A1 (en) *	1995-06-15	1996-12-16	Tsunehiko Fukuda	Parathyroid hormone derivatives and their use
US5723577A (en) *	1995-07-13	1998-03-03	Biomeasure Inc.	Analogs of parathyroid hormone

1997
- 1997-03-07 US US08/813,534 patent/US5955574A/en not_active Expired - Lifetime
- 1997-12-08 KR KR10-1999-7006165A patent/KR100497709B1/ko not_active IP Right Cessation
- 1997-12-08 SI SI9730730T patent/SI0948541T1/sl unknown
- 1997-12-08 BR BR9714200-0A patent/BR9714200A/pt not_active IP Right Cessation
- 1997-12-08 NZ NZ336610A patent/NZ336610A/en not_active IP Right Cessation
- 1997-12-08 EP EP05026436A patent/EP1645566B1/en not_active Expired - Lifetime
- 1997-12-08 ES ES97951595T patent/ES2258286T3/es not_active Expired - Lifetime
- 1997-12-08 CZ CZ20050594A patent/CZ301497B6/cs not_active IP Right Cessation
- 1997-12-08 AU AU55199/98A patent/AU741584B2/en not_active Ceased
- 1997-12-08 DK DK05026436.5T patent/DK1645566T3/da active
- 1997-12-08 DK DK97951595T patent/DK0948541T3/da active
- 1997-12-08 PT PT05026436T patent/PT1645566E/pt unknown
- 1997-12-08 SI SI9730795T patent/SI1645566T1/sl unknown
- 1997-12-08 EP EP97951595A patent/EP0948541B1/en not_active Expired - Lifetime
- 1997-12-08 RU RU99117145/04A patent/RU2198182C2/ru not_active IP Right Cessation
- 1997-12-08 AT AT05026436T patent/ATE471342T1/de active
- 1997-12-08 DE DE69735603T patent/DE69735603T2/de not_active Expired - Lifetime
- 1997-12-08 DE DE69739912T patent/DE69739912D1/de not_active Expired - Lifetime
- 1997-12-08 PL PL334438A patent/PL191898B1/pl not_active IP Right Cessation
- 1997-12-08 JP JP53086598A patent/JP3963482B2/ja not_active Expired - Fee Related
- 1997-12-08 IL IL13079497A patent/IL130794A0/xx not_active IP Right Cessation
- 1997-12-08 ES ES05026436T patent/ES2347154T3/es not_active Expired - Lifetime
- 1997-12-08 AT AT97951595T patent/ATE321784T1/de active
- 1997-12-08 CN CNB971819157A patent/CN1137898C/zh not_active Expired - Fee Related
- 1997-12-08 EP EP10156965A patent/EP2206725A1/en not_active Withdrawn
- 1997-12-08 CZ CZ0239899A patent/CZ298937B6/cs not_active IP Right Cessation
- 1997-12-08 CA CA002276614A patent/CA2276614C/en not_active Expired - Fee Related
- 1997-12-08 WO PCT/US1997/022498 patent/WO1998030590A2/en active IP Right Grant
- 1997-12-08 PT PT97951595T patent/PT948541E/pt unknown
- 1997-12-08 KR KR1020057003295A patent/KR100699422B1/ko not_active IP Right Cessation
- 1997-12-08 HU HU9904596A patent/HUP9904596A3/hu unknown
1998
- 1998-01-06 AR ARP980100058A patent/AR011517A1/es active IP Right Grant
1999
- 1999-07-06 NO NO993341A patent/NO993341L/no not_active Application Discontinuation
2000
- 2000-09-01 HK HK00105467A patent/HK1026215A1/xx not_active IP Right Cessation
2003
- 2003-02-17 AR ARP030100515A patent/AR038552A2/es active IP Right Grant
2006
- 2006-01-18 AR ARP060100191A patent/AR051906A2/es unknown

Also Published As

Publication number	Publication date
EP1645566B1 (en)	2010-06-16
DE69739912D1 (de)	2010-07-29
AU5519998A (en)	1998-08-03
CA2276614A1 (en)	1998-07-16
WO1998030590A9 (en)	1999-08-19
AU741584B2 (en)	2001-12-06
CA2276614C (en)	2002-06-11
AR051906A2 (es)	2007-02-14
EP2206725A1 (en)	2010-07-14
PL334438A1 (en)	2000-02-28
AR011517A1 (es)	2000-08-30
IL130794A0 (en)	2001-01-28
RU2198182C2 (ru)	2003-02-10
EP1645566A3 (en)	2006-10-11
PT1645566E (pt)	2010-08-31
KR100497709B1 (ko)	2005-06-23
JP3963482B2 (ja)	2007-08-22
JP2001508439A (ja)	2001-06-26
CZ298937B6 (cs)	2008-03-19
HUP9904596A3 (en)	2000-07-28
ES2347154T3 (es)	2010-10-26
CN1137898C (zh)	2004-02-11
SI0948541T1 (sl)	2006-06-30
SI1645566T1 (sl)	2010-11-30
CN1254347A (zh)	2000-05-24
NO993341D0 (no)	1999-07-06
PL191898B1 (pl)	2006-07-31
KR100699422B1 (ko)	2007-03-28
DE69735603T2 (de)	2006-11-30
KR20000069952A (ko)	2000-11-25
HUP9904596A1 (hu)	2000-06-28
BR9714200A (pt)	2000-03-28
ATE321784T1 (de)	2006-04-15
EP0948541A2 (en)	1999-10-13
WO1998030590A3 (en)	1998-12-10
KR20060030006A (ko)	2006-04-07
WO1998030590A2 (en)	1998-07-16
EP1645566A2 (en)	2006-04-12
CZ301497B6 (cs)	2010-03-24
ES2258286T3 (es)	2006-08-16
US5955574A (en)	1999-09-21
NZ336610A (en)	2001-07-27
AR038552A2 (es)	2005-01-19
DK1645566T3 (da)	2010-09-27
EP0948541B1 (en)	2006-03-29
PT948541E (pt)	2006-07-31
HK1026215A1 (en)	2000-12-08
NO993341L (no)	1999-09-06
DE69735603D1 (de)	2006-05-18
CZ239899A3 (cs)	2000-01-12
ATE471342T1 (de)	2010-07-15

Publication	Publication Date	Title
DK0948541T3 (da)	2006-07-17	Analoge af PTHrP
DE69638025D1 (de)	2009-10-22	Parathyroidhormon Analoge
BR9713294A (pt)	2000-10-17	"anticorpos contra proteìna relacionada a hormÈnio de paratiróide humano"
IL210454A (en)	2014-02-27	Antibody against a new ligand of cytokine 17zcytor
NZ527053A (en)	2005-04-29	Modified amyloid precursor protein polynucleotides and polypeptides
NO995568L (no)	1999-12-29	Paratyroidhormon peptidanaloger
DE69823046D1 (de)	2004-05-13	Praktische in vitro sialylierung von rekombinanten glykpproteinen
DK0682529T4 (da)	2006-05-15	Antistof til behandling af insulinkrævende diabetes
ATE304020T1 (de)	2005-09-15	Parathyroidhormon-verwandthe peptidanaloge
EA200001071A1 (ru)	2001-08-27	Способ получения полимер-связанных циклических пептидов
TR199700714A2 (xx)	1998-02-21	Paratiroit hormonu, analoglar�n�n sentezi i�in bir y�ntem.
ES2136458T3 (es)	1999-11-16	Metodo para separar la metionina n-terminal.
BR9815788B1 (pt)	2013-06-04	proteÍna quimÉrica.
NO971508L (no)	1997-06-13	Analoger av sur fibroblastvekstfaktor med forökt stabilitet og biologisk aktivitet
DK0427863T3 (da)	1996-07-29	DNA, som koder for protein, som kan kombinere med forstærker for alfa-fetoprotein-gen
DK0779297T3 (da)	2001-09-17	Antigene peptider med glycinsubstitutioner
DE69832064D1 (de)	2005-12-01	Transporterproteine spezifisch für Schilddrüsenhormone und deren Agonisten und Antagonisten