ATE304020T1 - Parathyroidhormon-verwandthe peptidanaloge - Google Patents

Parathyroidhormon-verwandthe peptidanaloge

Info

Publication number: ATE304020T1
Authority: AT; Austria
Prior art keywords: parathyroid hormone; related peptide; peptide analogs; pth; hormone related
Prior art date: 1996-07-31

Application number

AT97935197T

Other languages

English (en)

Inventor

Thomas J Gardella

Harald Jueppner

Original Assignee

Gen Hospital Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-07-31

Filing date

1997-07-30

Publication date

2005-09-15

1997-07-30 Application filed by Gen Hospital Corp filed Critical Gen Hospital Corp

2005-09-15 Application granted granted Critical

2005-09-15 Publication of ATE304020T1 publication Critical patent/ATE304020T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
- A61P5/20—Drugs for disorders of the endocrine system of the parathyroid hormones for decreasing, blocking or antagonising the activity of PTH
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Endocrinology (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Diabetes (AREA)
Zoology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Neurology (AREA)
Biophysics (AREA)
Toxicology (AREA)
Hematology (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Biomedical Technology (AREA)
Urology & Nephrology (AREA)
Obesity (AREA)
Neurosurgery (AREA)
Dermatology (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Spectrometry And Color Measurement (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT97935197T 1996-07-31 1997-07-30 Parathyroidhormon-verwandthe peptidanaloge ATE304020T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US2547196P	1996-07-31	1996-07-31
PCT/US1997/013360 WO1998004591A1 (en)	1996-07-31	1997-07-30	Novel parathyroid hormone-related peptide analogs

Publications (1)

Publication Number	Publication Date
ATE304020T1 true ATE304020T1 (de)	2005-09-15

Family

ID=21826255

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT97935197T ATE304020T1 (de)	1996-07-31	1997-07-30	Parathyroidhormon-verwandthe peptidanaloge

Country Status (8)

Country	Link
US (2)	US6147186A (de)
EP (1)	EP0917537B1 (de)
JP (2)	JP4142743B2 (de)
AT (1)	ATE304020T1 (de)
AU (1)	AU3819497A (de)
DE (1)	DE69734157T2 (de)
ES (1)	ES2248853T3 (de)
WO (1)	WO1998004591A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2248853T3 (es) *	1996-07-31	2006-03-16	The General Hospital Corporation	Nuevos analogos del peptido relacionado con la hormona paratiroidea.
ATE392431T1 (de)	1998-05-05	2008-05-15	Sod Conseils Rech Applic	Pth2 rezeptor selektive verbindungen
JP4486256B2 (ja) *	1998-10-22	2010-06-23	ザ・ジェネラル・ホスピタル・コーポレイション	副甲状腺ホルモン（ＰＴＨ）および副甲状腺ホルモン関連ペプチド（ＰＴＨｒＰ）の生物活性ペプチドおよびペプチド誘導体
WO2000077042A2 (en) *	1999-06-15	2000-12-21	The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services	Parathyroid hormone receptor ligands
AU7734800A (en) *	1999-09-29	2001-04-30	General Hospital Corporation, The	Polypeptide derivatives of parathyroid hormone (pth)
US6756480B2 (en)	2000-04-27	2004-06-29	Amgen Inc.	Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein
US20050124537A1 (en) *	2000-04-27	2005-06-09	Amgen Inc.	Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein
JP4837888B2 (ja) *	2001-07-23	2011-12-14	ザジェネラルホスピタルコーポレイション	コンホメーションが拘束された副甲状腺ホルモン（ｐｔｈ）類似体
EP1531855A4 (de) *	2002-01-10	2009-07-22	Osteotrophin Llc	Behandlung von knochenerkrankungen mit skelettalen anabolika
AU2003239869A1 (en) *	2002-05-23	2003-12-12	Michael Holick	Use of a parathyroid hormone peptide analogs for the treatment of vaginal atrophy
AU2002951372A0 (en) *	2002-09-13	2002-09-26	St Vincent's Institute Of Medical Research	Parathyroid hormone-like polypeptides
WO2004093902A1 (en) *	2003-03-19	2004-11-04	The General Hospital Corporation	CONFORMATIONALLY CONSTRAINED PARATHYROID HORMONES WITH α-HELIX STABILIZERS
US7910544B2 (en) *	2003-07-17	2011-03-22	The General Hospital Corporation	Conformationally constrained parthyroid hormone (PTH) analogs
AU2005244734A1 (en) *	2004-05-13	2005-12-01	Alza Corporation	Apparatus and method for transdermal delivery of parathyroid hormone agents
US20060068426A1 (en) *	2004-08-20	2006-03-30	Tam James P	Cyclic peptides and antibodies thereof
US20090022684A1 (en) *	2006-05-09	2009-01-22	Paul Morley	Methods for hematopoietic stimulation
JP2009545320A (ja) *	2006-08-04	2009-12-24	ザジェネラルホスピタルコーポレイション	副甲状腺ホルモン（ｐｔｈ）のポリペプチド誘導体
EP1961765A1 (de) *	2006-12-08	2008-08-27	Zealand Pharma A/S	Verkürzte PTH-Peptide mit zyklischer Konformation
EP2155874B1 (de)	2007-04-09	2016-05-11	The Board Of Trustees Of The University Of Arkansas	Fusionsproteine von collagen bindender domäne und parathormon
KR101661730B1 (ko) *	2007-08-01	2016-10-04	더 제너럴 하스피탈 코포레이션	Ｇ―단백질 결합 수용체를 이용한 스크리닝 방법 및 관련 조성물
EP2411038B1 (de)	2009-03-27	2016-12-28	Van Andel Research Institute	Parathryoidhormonpeptide und parathyroidhormonbezogene proteinpeptide sowie anwendungsverfahren dafür
SMT201900307T1 (it)	2009-07-29	2019-07-11	Kai Pharmaceuticals Inc	Agenti terapeutici per la riduzione dei livelli dell'ormone paratiroideo
EP2569003B1 (de)	2010-05-13	2017-10-25	The General Hospital Corporation	Parathyroidhormon-analoga und verwendungen davon
AU2012335009B2 (en) *	2011-11-10	2017-08-31	Kai Pharmaceuticals, Inc.	Calcimimetics and methods for their use
JP6366507B2 (ja)	2011-12-14	2018-08-01	ザボードオブトラスティーズオブザユニバーシティオブアーカンソー	コラーゲン結合タンパク質による治療剤の送達
US9526765B2 (en)	2012-02-09	2016-12-27	The Kitasato Institute	Delivery of therapeutic agents by a collagen binding protein
CN105431548B (zh)	2013-03-15	2025-06-17	生物医学研究机构基金会	用于癌转移的诊断、预后和治疗的方法
US11624060B2 (en)	2017-02-10	2023-04-11	The Board Of Trustees Of The University Of Arkansas	Collagen-binding agent compositions and methods of using the same
JP2021516222A (ja)	2018-03-16	2021-07-01	ザジェネラルホスピタルコーポレイション	副甲状腺ホルモンポリペプチドコンジュゲートおよびその使用方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE68921665T2 (de) *	1988-05-09	1995-09-21	Merck & Co Inc	Hemmer vom flüssigen kalziumerhöhenden Faktor.
JP3464796B2 (ja) *	1991-04-05	2003-11-10	ザジェネラルホスピタルコーポレーション	副甲状腺ホルモンのレセプターとそれをコードしているｄｎａ
US5589452A (en)	1992-07-14	1996-12-31	Syntex (U.S.A.) Inc.	Analogs of parathyroid hormone and parathyroid hormone related peptide: synthesis and use for the treatment of osteoporosis
US5821225A (en)	1992-07-14	1998-10-13	Syntex (U.S.A.) Inc.	Method for the treatment of corticosteroid induced osteopenia comprising administration of modified PTH or PTHrp
US5977070A (en)	1992-07-14	1999-11-02	Piazza; Christin Teresa	Pharmaceutical compositions for the nasal delivery of compounds useful for the treatment of osteoporosis
WO1995002610A1 (en) *	1993-07-13	1995-01-26	Syntex (U.S.A.) Inc.	Analogs of parathyroid hormone and parathyroid hormone related peptide: synthesis and use for the treatment of osteoporosis
CO4410206A1 (es) *	1994-07-28	1997-01-09	Sandoz Ag	DERIVADOS DE PTH o PTHrP, SU PREPARACION Y COMPOSICIONES FARMACEUTICAS QUE LAS COMPRENDEN
ES2248853T3 (es) *	1996-07-31	2006-03-16	The General Hospital Corporation	Nuevos analogos del peptido relacionado con la hormona paratiroidea.

1997
- 1997-07-30 ES ES97935197T patent/ES2248853T3/es not_active Expired - Lifetime
- 1997-07-30 WO PCT/US1997/013360 patent/WO1998004591A1/en active IP Right Grant
- 1997-07-30 EP EP97935197A patent/EP0917537B1/de not_active Expired - Lifetime
- 1997-07-30 DE DE69734157T patent/DE69734157T2/de not_active Expired - Lifetime
- 1997-07-30 AT AT97935197T patent/ATE304020T1/de not_active IP Right Cessation
- 1997-07-30 US US08/903,497 patent/US6147186A/en not_active Expired - Lifetime
- 1997-07-30 AU AU38194/97A patent/AU3819497A/en not_active Abandoned
- 1997-07-30 JP JP50911298A patent/JP4142743B2/ja not_active Expired - Fee Related
2000
- 2000-08-09 US US09/635,076 patent/US6362163B1/en not_active Expired - Lifetime
2007
- 2007-11-21 JP JP2007302159A patent/JP2008074868A/ja active Pending

Also Published As

Publication number	Publication date
WO1998004591A1 (en)	1998-02-05
AU3819497A (en)	1998-02-20
US6147186A (en)	2000-11-14
JP2008074868A (ja)	2008-04-03
DE69734157D1 (en)	2005-10-13
US6362163B1 (en)	2002-03-26
DE69734157T2 (de)	2006-07-13
JP4142743B2 (ja)	2008-09-03
ES2248853T3 (es)	2006-03-16
EP0917537A1 (de)	1999-05-26
EP0917537B1 (de)	2005-09-07
JP2001500476A (ja)	2001-01-16

Publication	Publication Date	Title
ATE304020T1 (de)	2005-09-15	Parathyroidhormon-verwandthe peptidanaloge
HUP9904596A1 (hu)	2000-06-28	Mellékpajzsmirigy-hormon analógok
HUP9901718A2 (hu)	1999-09-28	Parathyroid hormon analógok
EA199901025A1 (ru)	2000-06-26	Пептидные аналоги паратиреоидного гормона
IL163066A (en)	2011-08-31	Ligands for the zcytor17 receptor
ES458691A1 (es)	1978-08-16	Procedimiento para preparar polipeptidos.
AU1918300A (en)	2000-06-13	Amino-terminal modified parathyroid hormone (pth) analogs
DK0736039T3 (da)	2001-02-12	Forbindelser med væksthormon-frigivende egenskaber
AU6286986A (en)	1987-03-10	Peptide analogues of mammalian insulin-like growth factor-1
ES2091317T3 (es)	1996-11-01	Metodo para la deteccion cuantitativa de tirotropina (tsh) o de autoanticuerpos de receptores de antitirotropina (anti-tshr), utilizando un polipeptido receptor de tirotropina recombinante, y kit para realizar dicho metodo.
EP0334244A3 (de)	1991-05-29	Peptide-Antagonisten von Bradykinin
GR3024580T3 (en)	1997-12-31	Rat C-type natriuretic peptide cDNA and precursor protein
WO2001023521A3 (en)	2001-08-23	Polypeptide derivatives of parathyroid hormone (PTH)
MX9705719A (es)	1998-02-28	Metodo para la sintesis de analogos de la hormona paratiroidea y del peptido relacionado con la hormona paratioridea.
ES2095255T3 (es)	1997-02-16	Analogos de sustitucion de peptidos magainina.
ATE111090T1 (de)	1994-09-15	Verfahren zur stereoselektiven herstellung von 8- g(a),12-oxido-13,14,15,16-tetranorlabdan.
DE60040678D1 (en)	2008-12-11	Parathyroid hormon (pth) polypeptidderivate
ES8207511A1 (es)	1982-10-01	Un procedimiento para la preparacion de nuevos peptidos.
ZA916918B (en)	1993-03-01	Amino acid analogs as CCK antagonists.
ES2114220T3 (es)	1998-05-16	Peptido inhibidor de la fosfolipasa c.
PT87239A (pt)	1988-05-01	Process for the preparation of peptides
JPS5434734A (en)	1979-03-14	Priority deciding circuit
JPS5572153A (en)	1980-05-30	Undecapeptide
NO950114L (no)	1995-03-10	Amylin-antagonister og agonister
JPS5347511A (en)	1978-04-28	Novel peptide extracted from frog skin

Legal Events

Date	Code	Title	Description
2006-03-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties