DK0674630T3 - 7-Halogen- og 7beta,8beta-methano-taxoler, antineoplastisk anvendelse og farmaceutiske præparater indeholdende dem - Google Patents

7-Halogen- og 7beta,8beta-methano-taxoler, antineoplastisk anvendelse og farmaceutiske præparater indeholdende dem

Info

Publication number: DK0674630T3
Authority: DK; Denmark
Prior art keywords: cancer; 8beta; 7beta; taxols; methano
Prior art date: 1992-12-15

Application number

DK94903483T

Other languages

Danish (da)

English (en)

Inventor

Harvey I Skulnick

Roy A Johnson

Jackson B Hester Jr

Robert C Kelly

Eldon G Midy

Original Assignee

Upjohn Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-12-15

Filing date

1993-12-13

Publication date

2003-02-24

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27486333&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0674630(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1993-12-13 Application filed by Upjohn Co filed Critical Upjohn Co

2003-02-24 Application granted granted Critical

2003-02-24 Publication of DK0674630T3 publication Critical patent/DK0674630T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D263/06—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Oncology (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Epoxy Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK94903483T 1992-12-15 1993-12-13 7-Halogen- og 7beta,8beta-methano-taxoler, antineoplastisk anvendelse og farmaceutiske præparater indeholdende dem DK0674630T3 (da)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US99057992A	1992-12-15	1992-12-15
US1382693A	1993-02-02	1993-02-02
US7633793A	1993-06-11	1993-06-11
US12297493A	1993-09-17	1993-09-17
PCT/US1993/011827 WO1994013655A1 (en)	1992-12-15	1993-12-13	7-HALO- AND 7β,8β-METHANO-TAXOLS, ANTINEOPLASTIC USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Publications (1)

Publication Number	Publication Date
DK0674630T3 true DK0674630T3 (da)	2003-02-24

Family

ID=27486333

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK94903483T DK0674630T3 (da)	1992-12-15	1993-12-13	7-Halogen- og 7beta,8beta-methano-taxoler, antineoplastisk anvendelse og farmaceutiske præparater indeholdende dem

Country Status (26)

Country	Link
US (1)	US6911549B1 (no)
EP (1)	EP0674630B1 (no)
JP (1)	JP3441458B2 (no)
KR (1)	KR100317015B1 (no)
CN (2)	CN1062561C (no)
AT (1)	ATE226576T1 (no)
AU (1)	AU687027B2 (no)
CA (1)	CA2149021A1 (no)
CZ (1)	CZ291177B6 (no)
DE (1)	DE69332438T2 (no)
DK (1)	DK0674630T3 (no)
ES (1)	ES2187519T3 (no)
FI (1)	FI111633B (no)
HU (1)	HUT74447A (no)
IL (1)	IL107950A (no)
LV (1)	LV13023B (no)
MX (1)	MX9307777A (no)
MY (1)	MY116473A (no)
NO (1)	NO313801B1 (no)
NZ (1)	NZ259196A (no)
PL (1)	PL185042B1 (no)
PT (1)	PT674630E (no)
RU (1)	RU2125996C1 (no)
SK (1)	SK281897B6 (no)
TW (1)	TW389758B (no)
WO (1)	WO1994013655A1 (no)

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US5973160A (en)	1992-12-23	1999-10-26	Poss; Michael A.	Methods for the preparation of novel sidechain-bearing taxanes
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GB9409131D0 (en) *	1994-05-09	1994-06-29	Erba Carlo Spa	Unsaturated taxane compounds
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JPH09507864A (ja) *	1994-11-04	1997-08-12	フアルマシア・エツセ・ピー・アー	タキサン誘導体
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FR2732342B1 (fr) *	1995-04-03	1997-04-30	Rhone Poulenc Rorer Sa	Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2742751B1 (fr) *	1995-12-22	1998-01-30	Rhone Poulenc Rorer Sa	Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
US5635531A (en) *	1996-07-08	1997-06-03	Bristol-Myers Squibb Company	3'-aminocarbonyloxy paclitaxels
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IL145635A0 (en) *	2000-02-02	2002-06-30	Univ Florida State Res Found	Taxane formulations having improved solubility
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CA2354478A1 (en) *	2001-07-31	2003-01-31	Florida State University Research Foundation, Inc.	C10 carbonate substituted taxanes
SG125888A1 (en) *	2001-08-01	2006-10-30	Univ Florida State Res Found	C10 carbonate substituted taxanes
JP2006513152A (ja) *	2002-10-09	2006-04-20	ファイトジェンライフサイエンシズインコーポレイテッド	新規タキサンならびにその使用および調製に関する方法
US8703982B2 (en)	2003-03-17	2014-04-22	Phyton Holdings Llc	Purification of taxanes
HN2005000054A (es)	2004-02-13	2009-02-18	Florida State University Foundation Inc	Taxanos sustituidos con esteres de ciclopentilo en c10
EP3345632A1 (en) *	2005-02-18	2018-07-11	Abraxis BioScience, LLC	Drugs with improved hydrophobicity for incorporation in medical devices
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WO2009019534A2 (en)	2006-10-12	2009-02-12	Bellus Health (International) Limited	Methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid
EP2789628A3 (en)	2007-05-29	2015-03-04	Angiochem Inc.	Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues
EP2183234A4 (en) *	2007-08-22	2012-02-29	Canada Inc 6570763	PROCESS FOR CONVERTING 9-DIHYDRO-13-ACETYLBACCATIN III IN DOCETAXEL OR PACLITAXEL
EP2080764B1 (en)	2008-01-18	2012-08-22	INDENA S.p.A.	Solid forms of ortataxel
JP2011517455A (ja)	2008-03-31	2011-06-09	フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド	Ｃ（１０）エチルエステルおよびｃ（１０）シクロプロピルエステル置換タキサン
KR101014438B1 (ko) *	2008-09-26	2011-02-14	동아제약주식회사	탁산 유도체의 제조방법
CN101648973B (zh) *	2009-09-03	2012-05-30	漆又毛	水溶性紫杉烷及制备方法
CA2803646A1 (en)	2010-07-02	2012-01-05	Angiochem Inc.	Short and d-amino acid-containing polypeptides for therapeutic conjugates and uses thereof
US8791279B2 (en) *	2010-12-13	2014-07-29	Yung Shin Pharm. Ind. Co., Ltd.	Process for preparing taxoids from baccatin derivatives using lewis acid catalyst
WO2013063504A1 (en)	2011-10-26	2013-05-02	H. Lee Moffitt Cancer Center & Research Institute, Inc.	Platinum compounds that inhibit constitutive stat3 signaling and induce cell cycle arrest and apoptosis of malignant cells
ES2826827T3 (es)	2015-06-15	2021-05-19	Angiochem Inc	Métodos para el tratamiento de carcinomatosis leptomeníngea
CN111138386A (zh) *	2019-12-30	2020-05-12	重庆市碚圣医药科技股份有限公司	一种多西他赛的半合成方法
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FR2696459B1 (fr)	1992-10-05	1994-11-25	Rhone Poulenc Rorer Sa	Procédé de préparation de dérivés du taxane.
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1993
- 1993-12-09 MX MX9307777A patent/MX9307777A/es not_active IP Right Cessation
- 1993-12-09 IL IL10795093A patent/IL107950A/en not_active IP Right Cessation
- 1993-12-13 SK SK788-95A patent/SK281897B6/sk unknown
- 1993-12-13 PL PL93309392A patent/PL185042B1/pl not_active IP Right Cessation
- 1993-12-13 CZ CZ19951437A patent/CZ291177B6/cs not_active IP Right Cessation
- 1993-12-13 AU AU57411/94A patent/AU687027B2/en not_active Ceased
- 1993-12-13 AT AT94903483T patent/ATE226576T1/de not_active IP Right Cessation
- 1993-12-13 KR KR1019950702435A patent/KR100317015B1/ko not_active Expired - Fee Related
- 1993-12-13 HU HU9501733A patent/HUT74447A/hu unknown
- 1993-12-13 DE DE69332438T patent/DE69332438T2/de not_active Expired - Fee Related
- 1993-12-13 CA CA002149021A patent/CA2149021A1/en not_active Abandoned
- 1993-12-13 NZ NZ259196A patent/NZ259196A/en unknown
- 1993-12-13 DK DK94903483T patent/DK0674630T3/da active
- 1993-12-13 JP JP51431294A patent/JP3441458B2/ja not_active Expired - Fee Related
- 1993-12-13 EP EP94903483A patent/EP0674630B1/en not_active Expired - Lifetime
- 1993-12-13 WO PCT/US1993/011827 patent/WO1994013655A1/en active IP Right Grant
- 1993-12-13 PT PT94903483T patent/PT674630E/pt unknown
- 1993-12-13 US US08/454,210 patent/US6911549B1/en not_active Expired - Fee Related
- 1993-12-13 RU RU95114377A patent/RU2125996C1/ru not_active IP Right Cessation
- 1993-12-13 ES ES94903483T patent/ES2187519T3/es not_active Expired - Lifetime
- 1993-12-15 MY MYPI93002715A patent/MY116473A/en unknown
- 1993-12-15 TW TW082110645A patent/TW389758B/zh not_active IP Right Cessation
- 1993-12-15 CN CN93121129A patent/CN1062561C/zh not_active Expired - Fee Related
1995
- 1995-06-14 NO NO19952351A patent/NO313801B1/no unknown
- 1995-06-14 FI FI952920A patent/FI111633B/fi not_active IP Right Cessation
1999
- 1999-11-25 CN CN99124350A patent/CN1261072A/zh active Pending
2003
- 2003-03-06 LV LVP-03-27A patent/LV13023B/en unknown

Also Published As

Publication number	Publication date
ATE226576T1 (de)	2002-11-15
LV13023B (en)	2003-12-20
JP3441458B2 (ja)	2003-09-02
CN1062561C (zh)	2001-02-28
CN1095377A (zh)	1994-11-23
IL107950A (en)	2001-04-30
RU2125996C1 (ru)	1999-02-10
EP0674630B1 (en)	2002-10-23
FI111633B (fi)	2003-08-29
DE69332438D1 (de)	2002-11-28
KR950704288A (ko)	1995-11-17
CZ291177B6 (cs)	2003-01-15
EP0674630A1 (en)	1995-10-04
NZ259196A (en)	1998-08-26
DE69332438T2 (de)	2003-06-18
JPH08506568A (ja)	1996-07-16
PL185042B1 (pl)	2003-02-28
KR100317015B1 (ko)	2002-06-22
MX9307777A (es)	1994-07-29
PT674630E (pt)	2003-03-31
CN1261072A (zh)	2000-07-26
TW389758B (en)	2000-05-11
PL309392A1 (en)	1995-10-02
CZ143795A3 (en)	1995-11-15
NO313801B1 (no)	2002-12-02
HUT74447A (en)	1996-12-30
CA2149021A1 (en)	1994-06-23
SK78895A3 (en)	1995-12-06
ES2187519T3 (es)	2003-06-16
AU687027B2 (en)	1998-02-19
RU95114377A (ru)	1997-06-10
WO1994013655A1 (en)	1994-06-23
NO952351D0 (no)	1995-06-14
IL107950A0 (en)	1994-04-12
AU5741194A (en)	1994-07-04
US6911549B1 (en)	2005-06-28
SK281897B6 (sk)	2001-09-11
FI952920A0 (fi)	1995-06-14
HU9501733D0 (en)	1995-08-28
FI952920L (fi)	1995-06-14
MY116473A (en)	2004-02-28
NO952351L (no)	1995-08-14

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