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DE69325262D1 - Vinylen-azaindolderivate und verfahren zu ihrer herstellung - Google Patents

Vinylen-azaindolderivate und verfahren zu ihrer herstellung

Info

Publication number
DE69325262D1
DE69325262D1 DE69325262T DE69325262T DE69325262D1 DE 69325262 D1 DE69325262 D1 DE 69325262D1 DE 69325262 T DE69325262 T DE 69325262T DE 69325262 T DE69325262 T DE 69325262T DE 69325262 D1 DE69325262 D1 DE 69325262D1
Authority
DE
Germany
Prior art keywords
azaine
vinylene
derivatives
production
variables
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69325262T
Other languages
English (en)
Other versions
DE69325262T2 (de
Inventor
Franco Buzetti
Angelo Crugnola
Dario Ballinari
Felicita Greco
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Pharmacia and Upjohn SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia and Upjohn SpA filed Critical Pharmacia and Upjohn SpA
Publication of DE69325262D1 publication Critical patent/DE69325262D1/de
Application granted granted Critical
Publication of DE69325262T2 publication Critical patent/DE69325262T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69325262T 1992-12-23 1993-12-15 Vinylen-azaindolderivate und verfahren zu ihrer herstellung Expired - Fee Related DE69325262T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929226855A GB9226855D0 (en) 1992-12-23 1992-12-23 Vinylene-azaindole derivatives and process for their preparation
PCT/EP1993/003536 WO1994014808A1 (en) 1992-12-23 1993-12-15 Vinylene-azaindole derivatives and process for their preparation

Publications (2)

Publication Number Publication Date
DE69325262D1 true DE69325262D1 (de) 1999-07-15
DE69325262T2 DE69325262T2 (de) 2000-01-20

Family

ID=10727139

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69325262T Expired - Fee Related DE69325262T2 (de) 1992-12-23 1993-12-15 Vinylen-azaindolderivate und verfahren zu ihrer herstellung

Country Status (24)

Country Link
US (1) US5397787A (de)
EP (1) EP0626963B1 (de)
JP (1) JP3507497B2 (de)
KR (1) KR950700296A (de)
CN (1) CN1093707A (de)
AT (1) ATE181074T1 (de)
AU (1) AU670488B2 (de)
CA (1) CA2126228A1 (de)
DE (1) DE69325262T2 (de)
DK (1) DK0626963T3 (de)
ES (1) ES2134926T3 (de)
FI (1) FI943838A0 (de)
GB (1) GB9226855D0 (de)
GR (1) GR3030941T3 (de)
HU (1) HUT67431A (de)
IL (1) IL108087A (de)
MX (1) MX9400206A (de)
MY (1) MY109695A (de)
NZ (1) NZ259330A (de)
PL (1) PL304894A1 (de)
RU (1) RU94040390A (de)
TW (1) TW296383B (de)
WO (1) WO1994014808A1 (de)
ZA (1) ZA939578B (de)

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IL108087A0 (en) 1994-04-12
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US5397787A (en) 1995-03-14
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