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DE60027578D1 - Verfahren zum Nachweis von Bioanalyten mittels metallische Nanohüllen - Google Patents

Verfahren zum Nachweis von Bioanalyten mittels metallische Nanohüllen

Info

Publication number
DE60027578D1
DE60027578D1 DE60027578T DE60027578T DE60027578D1 DE 60027578 D1 DE60027578 D1 DE 60027578D1 DE 60027578 T DE60027578 T DE 60027578T DE 60027578 T DE60027578 T DE 60027578T DE 60027578 D1 DE60027578 D1 DE 60027578D1
Authority
DE
Germany
Prior art keywords
core
nanoshells
particles
shell
metal shell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60027578T
Other languages
English (en)
Other versions
DE60027578T2 (de
Inventor
L West
L Halas
J Oldenburg
D Averitt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
William Marsh Rice University
Original Assignee
William Marsh Rice University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by William Marsh Rice University filed Critical William Marsh Rice University
Publication of DE60027578D1 publication Critical patent/DE60027578D1/de
Application granted granted Critical
Publication of DE60027578T2 publication Critical patent/DE60027578T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/587—Nanoparticles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G01N21/658—Raman scattering enhancement Raman, e.g. surface plasmons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/588—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with semiconductor nanocrystal label, e.g. quantum dots
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2002/00—Crystal-structural characteristics
    • C01P2002/80—Crystal-structural characteristics defined by measured data other than those specified in group C01P2002/70
    • C01P2002/82—Crystal-structural characteristics defined by measured data other than those specified in group C01P2002/70 by IR- or Raman-data
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2002/00—Crystal-structural characteristics
    • C01P2002/80—Crystal-structural characteristics defined by measured data other than those specified in group C01P2002/70
    • C01P2002/84—Crystal-structural characteristics defined by measured data other than those specified in group C01P2002/70 by UV- or VIS- data
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/01—Particle morphology depicted by an image
    • C01P2004/04—Particle morphology depicted by an image obtained by TEM, STEM, STM or AFM
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/10—Particle morphology extending in one dimension, e.g. needle-like
    • C01P2004/12—Particle morphology extending in one dimension, e.g. needle-like with a cylindrical shape
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/30—Particle morphology extending in three dimensions
    • C01P2004/32—Spheres
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/30—Particle morphology extending in three dimensions
    • C01P2004/38—Particle morphology extending in three dimensions cube-like
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/54—Particles characterised by their aspect ratio, i.e. the ratio of sizes in the longest to the shortest dimension
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/60—Particles characterised by their size
    • C01P2004/61—Micrometer sized, i.e. from 1-100 micrometer
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/60—Particles characterised by their size
    • C01P2004/62—Submicrometer sized, i.e. from 0.1-1 micrometer
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2004/00—Particle morphology
    • C01P2004/60—Particles characterised by their size
    • C01P2004/64—Nanometer sized, i.e. from 1-100 nanometer

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Nanotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Materials Engineering (AREA)
  • Composite Materials (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
DE60027578T 1999-07-16 2000-07-14 Verfahren zum Nachweis von Bioanalyten unter Verwendung metallischer Nanohüllen Expired - Lifetime DE60027578T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14413699P 1999-07-16 1999-07-16
US144136P 1999-07-16
PCT/US2000/019375 WO2001006257A1 (en) 1999-07-16 2000-07-14 Metal nanoshells for biosensing applications

Publications (2)

Publication Number Publication Date
DE60027578D1 true DE60027578D1 (de) 2006-06-01
DE60027578T2 DE60027578T2 (de) 2007-01-25

Family

ID=22507232

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60027578T Expired - Lifetime DE60027578T2 (de) 1999-07-16 2000-07-14 Verfahren zum Nachweis von Bioanalyten unter Verwendung metallischer Nanohüllen

Country Status (6)

Country Link
EP (1) EP1210600B1 (de)
JP (2) JP2003504642A (de)
AT (1) ATE324587T1 (de)
CA (1) CA2377722A1 (de)
DE (1) DE60027578T2 (de)
WO (1) WO2001006257A1 (de)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001236798B2 (en) 2000-02-08 2004-11-04 Rice University Optically-active nanoparticles for use in therapeutic and diagnostic methods
US6707548B2 (en) 2001-02-08 2004-03-16 Array Bioscience Corporation Systems and methods for filter based spectrographic analysis
CN1982868A (zh) * 2001-03-09 2007-06-20 福冈隆夫 分散复合体及其制造方法
GB0112238D0 (en) * 2001-05-18 2001-07-11 Medical Biosystems Ltd Sequencing method
US7238472B2 (en) * 2001-05-25 2007-07-03 Nanosphere, Inc. Non-alloying core shell nanoparticles
US7147687B2 (en) 2001-05-25 2006-12-12 Nanosphere, Inc. Non-alloying core shell nanoparticles
DE10131173C2 (de) * 2001-06-29 2003-12-04 Itn Nanovation Gmbh Verfahren zur Herstellung von Kern-Hülle-Teilchen und deren Verwendung
AU2003247722A1 (en) * 2002-06-28 2004-01-19 Purdue Research Foundation Magnetic nanomaterials and methods for detection of biological materials
ES2431520T3 (es) 2003-01-25 2013-11-26 Seno Medical Instruments, Inc. Procedimiento de formación de imágenes optoacústicas de contraste elevado utilizando nanopartículas no esféricas
CA2557348A1 (en) * 2003-02-25 2004-09-10 Xmx Corporation Encapsulated nanoparticles for the absorption of electromagnetic energy
WO2005023535A2 (en) * 2003-02-25 2005-03-17 Xmx Corporation Encapsulated nanoparticles for the absorption of electromagnetic energy in ultraviolet range
CN1514243A (zh) * 2003-04-30 2004-07-21 成都夸常科技有限公司 对目标物进行定性和/或定量分析的方法、装置和标记物及检测试剂盒
EP1624306A4 (de) * 2003-04-30 2008-12-24 Chengdu Kuachang Medical Ind L Zur trennung oder analyse verwendete nanostrukturen enthaltende vorrichtung sowie herstellung und anwendung davon
IL156626A (en) 2003-06-24 2009-12-24 Yeda Res & Dev System for selective cell destruction
JP2005195441A (ja) 2004-01-07 2005-07-21 Fuji Photo Film Co Ltd ラマン分光方法および装置並びにラマン分光用デバイス
JP5502279B2 (ja) * 2004-10-28 2014-05-28 エコー セラピューティクス， インコーポレイテッド ヒドロゲルを使用した検体のサンプリングおよび分析のためのシステムおよび方法
US7599066B2 (en) * 2005-06-01 2009-10-06 Canon Kabushiki Kaisha Localized plasmon resonance sensor
WO2007050555A2 (en) * 2005-10-24 2007-05-03 Wait W Bradley Resonant nanostructures and methods of use
EP1977242B1 (de) * 2006-01-27 2016-08-03 Becton Dickinson and Company Querfluss-immuntest mit eingekapselter erkennungsmodalität
JP5099369B2 (ja) * 2006-05-01 2012-12-19 富士レビオ株式会社 金属コーティングにてカプセル化された非金属蛍光粒子
KR20100061603A (ko) * 2008-11-29 2010-06-08 한국전자통신연구원 바이오 물질 감지용 나노 입자 및 이를 이용한 바이오 센서
TWI552369B (zh) * 2009-09-25 2016-10-01 伊穆諾萊特公司 用以改良太陽能電池效能或其它能量轉換之上、下轉換系統
ES2359411B1 (es) * 2009-10-19 2012-04-03 Universidad De Zaragoza Método de autenticación de objetos.
CN102811943B (zh) * 2009-12-11 2015-08-19 韩国化学研究院 以位于粒子间的结合部的拉曼活性分子标记的二聚体核壳纳米结构、其用途及制备方法
WO2011091307A1 (en) * 2010-01-23 2011-07-28 University Of Connecticut Affinity hydrogels for controlled protein release
ES2618869T3 (es) * 2010-03-22 2017-06-22 Sicpa Holding Sa Una nanoetiqueta de SERS de longitud de onda selectiva
US9061056B2 (en) 2010-08-27 2015-06-23 Sienna Labs, Inc. Compositions and methods for targeted thermomodulation
US9572880B2 (en) 2010-08-27 2017-02-21 Sienna Biopharmaceuticals, Inc. Ultrasound delivery of nanoparticles
US10994992B2 (en) 2011-01-20 2021-05-04 Technion Research & Development Foundation Limited Method and system for manipulating a cell
WO2012149026A2 (en) * 2011-04-25 2012-11-01 The Research Foundation Of State University Of New York Spectral modification
US9150413B2 (en) * 2011-05-13 2015-10-06 Imec Waveguide-integrated plasmonic resonator for integrated SERS measurements
JP5762225B2 (ja) * 2011-09-08 2015-08-12 新留　康郎 銀シェル金ナノロッドを用いる分析方法
IL305614B2 (en) 2012-10-11 2024-09-01 Nanocomposix Inc Silver nanoplate compositions and methods
CN103808706A (zh) * 2012-11-06 2014-05-21 厦门大学 一种含针孔的壳层纳米粒子拉曼光谱检测增强剂及应用该增强剂进行拉曼光谱检测的方法
DE102013008104A1 (de) * 2013-05-14 2014-11-20 Laser-Laboratorium Göttingen e.V. SERS-Substrat
DE102013106432A1 (de) * 2013-06-20 2014-12-24 Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG Optische Indikator-Einheit und Vorrichtung und Verfahren zur Bestimmung einer physikalisch-chemischen Eigenschaft eines Prozessmediums in einer prozesstechnischen Anlage
US10359366B2 (en) 2013-08-23 2019-07-23 Ukon Craft Science Ltd. Substrate for surface enhanced Raman scattering spectroscopy and devices using same
WO2016051666A1 (ja) * 2014-09-30 2016-04-07 富士フイルム株式会社 炭酸ガスセンシング用の光電場増強デバイス
US11111396B2 (en) * 2014-10-17 2021-09-07 C3 Nano, Inc. Transparent films with control of light hue using nanoscale colorants
KR102127146B1 (ko) * 2017-08-08 2020-06-26 사회복지법인 삼성생명공익재단 플라즈모닉 효과를 이용한 질병의 진단에 필요한 정보 제공 방법 및 질병 진단용 슬라이드
CN110554018A (zh) * 2018-05-31 2019-12-10 上海市刑事科学技术研究院 检测水溶液中4-溴甲卡西酮的表面增强拉曼材料及其制备方法
JP7079923B2 (ja) * 2018-07-18 2022-06-03 公立大学法人名古屋市立大学 Ｓｅｒｓ測定用材料及びその製造方法
CN111375759B (zh) * 2018-12-28 2021-10-01 同方威视技术股份有限公司 一种拉曼纳米增强材料及其制备方法和应用
CN110849863B (zh) * 2019-10-15 2020-11-24 中国人民解放军第二军医大学 一种检测适配体与配体小分子结合过程中构象改变的方法
CN114942240B (zh) * 2022-05-30 2022-12-13 武汉太赫光学科技有限公司 上转换拉曼传感器及应用
CN115266680B (zh) * 2022-08-30 2024-07-16 中国计量大学 一种桑椹汁中胭脂红的定量检测方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5935779A (en) * 1988-11-03 1999-08-10 Igen International Inc. Methods for improved particle electrochemiluminescence assay
US5962218A (en) * 1988-11-03 1999-10-05 Igen International Inc. Methods and apparatus for improved luminescence assays
US5779976A (en) * 1988-11-03 1998-07-14 Igen International, Inc. Apparatus for improved luminescence assays
US5023139A (en) * 1989-04-04 1991-06-11 Research Corporation Technologies, Inc. Nonlinear optical materials
US5376556A (en) * 1989-10-27 1994-12-27 Abbott Laboratories Surface-enhanced Raman spectroscopy immunoassay
IL100866A (en) * 1991-02-06 1995-10-31 Igen Inc Luminescence test method and device based on magnetic tiny particles, containing many magnets
USH1447H (en) * 1992-11-20 1995-06-06 E. I. Du Pont De Nemours And Company Coated silica shells
JPH07146295A (ja) * 1993-11-19 1995-06-06 Kyoto Daiichi Kagaku:Kk ラマン分光測定による免疫分析方法及び装置
JP2965502B2 (ja) * 1996-02-20 1999-10-18 株式会社京都第一科学 表面増強ラマン散乱測定による分析方法
EP1818417B1 (de) * 1996-07-29 2014-02-12 Nanosphere, Inc. Nanopartikel mit angehängten Oligonukleotiden und ihre Verwendungen
US5898004A (en) * 1996-11-06 1999-04-27 University Of Pittsburgh Of The Commonwealth System Of Higher Education Polymerized crystalline colloidal array sensors
US5939021A (en) * 1997-01-23 1999-08-17 Hansen; W. Peter Homogeneous binding assay
US6344272B1 (en) * 1997-03-12 2002-02-05 Wm. Marsh Rice University Metal nanoshells
US5990479A (en) * 1997-11-25 1999-11-23 Regents Of The University Of California Organo Luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes
CA2379357C (en) * 1999-07-16 2011-03-22 Wm. Marsh Rice University Temperature-sensitive polymer/nanoshell composites for photothermally modulated drug delivery

Also Published As

Publication number Publication date
ATE324587T1 (de) 2006-05-15
WO2001006257A8 (en) 2001-11-29
EP1210600A4 (de) 2003-05-21
WO2001006257A1 (en) 2001-01-25
CA2377722A1 (en) 2001-01-25
EP1210600A1 (de) 2002-06-05
JP2003504642A (ja) 2003-02-04
JP2010230679A (ja) 2010-10-14
DE60027578T2 (de) 2007-01-25
EP1210600B1 (de) 2006-04-26

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