DE60027564D1 - Tek-antagonisten - Google Patents
Tek-antagonistenInfo
- Publication number
- DE60027564D1 DE60027564D1 DE60027564T DE60027564T DE60027564D1 DE 60027564 D1 DE60027564 D1 DE 60027564D1 DE 60027564 T DE60027564 T DE 60027564T DE 60027564 T DE60027564 T DE 60027564T DE 60027564 D1 DE60027564 D1 DE 60027564D1
- Authority
- DE
- Germany
- Prior art keywords
- tek antagonists
- methods
- tek
- antagonists
- angiogenesis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13788999P | 1999-06-07 | 1999-06-07 | |
US137889P | 1999-06-07 | ||
PCT/US2000/015706 WO2000075323A1 (en) | 1999-06-07 | 2000-06-07 | Tek antagonists |
Publications (3)
Publication Number | Publication Date |
---|---|
DE60027564D1 true DE60027564D1 (de) | 2006-06-01 |
DE60027564T2 DE60027564T2 (de) | 2007-05-10 |
DE60027564T3 DE60027564T3 (de) | 2009-07-23 |
Family
ID=22479496
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60027564T Expired - Lifetime DE60027564T3 (de) | 1999-06-07 | 2000-06-07 | Tek-antagonisten |
Country Status (14)
Country | Link |
---|---|
US (2) | US6413932B1 (de) |
EP (1) | EP1187918B9 (de) |
JP (1) | JP4587626B2 (de) |
AT (1) | ATE324444T1 (de) |
AU (1) | AU783960B2 (de) |
CA (1) | CA2374851A1 (de) |
CY (1) | CY1105078T1 (de) |
DE (1) | DE60027564T3 (de) |
DK (1) | DK1187918T4 (de) |
ES (1) | ES2262518T5 (de) |
IL (2) | IL146482A0 (de) |
NZ (1) | NZ516258A (de) |
PT (1) | PT1187918E (de) |
WO (1) | WO2000075323A1 (de) |
Families Citing this family (105)
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ES2523837T3 (es) | 2003-07-18 | 2014-12-01 | Amgen Inc. | Agentes de unión específica al factor de crecimiento de hepatocitos |
EP1745073A2 (de) * | 2004-05-14 | 2007-01-24 | Receptor Biologix, Inc. | Isoformen eines zelloberflächenrezeptors und verfahren zu deren identifizierung und anwendung |
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AR059066A1 (es) | 2006-01-27 | 2008-03-12 | Amgen Inc | Combinaciones del inhibidor de la angiopoyetina -2 (ang2) y el inhibidor del factor de crecimiento endotelial vascular (vegf) |
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PE20121506A1 (es) | 2006-07-14 | 2012-11-26 | Amgen Inc | Compuestos triazolopiridinas como inhibidores de c-met |
AU2008219166B2 (en) | 2007-02-16 | 2013-05-16 | Amgen Inc. | Nitrogen-containing heterocyclyl ketones and their use as c-Met inhibitors |
PL2188313T3 (pl) | 2007-08-21 | 2018-04-30 | Amgen, Inc. | Białka wiążące ludzki antygen c-fms |
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US8557243B2 (en) | 2008-01-03 | 2013-10-15 | The Scripps Research Institute | EFGR antibodies comprising modular recognition domains |
US8454960B2 (en) | 2008-01-03 | 2013-06-04 | The Scripps Research Institute | Multispecific antibody targeting and multivalency through modular recognition domains |
US8557242B2 (en) | 2008-01-03 | 2013-10-15 | The Scripps Research Institute | ERBB2 antibodies comprising modular recognition domains |
US8574577B2 (en) | 2008-01-03 | 2013-11-05 | The Scripps Research Institute | VEGF antibodies comprising modular recognition domains |
AU2009209251B8 (en) | 2008-01-28 | 2015-03-26 | Medimmune Limited | Stabilized Angiopoietin-2 antibodies and uses thereof |
JO2913B1 (en) | 2008-02-20 | 2015-09-15 | امجين إنك, | Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses |
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CN103857699B (zh) | 2011-05-24 | 2016-08-31 | 泽恩格尼亚股份有限公司 | 多价和单价多特异性复合物及其用途 |
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US10316105B2 (en) | 2011-08-19 | 2019-06-11 | Regeneron Pharmaceuticals, Inc. | Anti-TIE2 antibodies and uses thereof |
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EP2968541A4 (de) | 2013-03-15 | 2017-02-08 | Zyngenia, Inc. | Multivalente und monovalente multispezifische komplexe und deren verwendungen |
TW201605896A (zh) | 2013-08-30 | 2016-02-16 | 安美基股份有限公司 | Gitr抗原結合蛋白 |
MX2018010851A (es) | 2016-03-08 | 2019-02-07 | Janssen Biotech Inc | Anticuerpos de gitr, métodos, y usos. |
RS62456B1 (sr) | 2016-12-22 | 2021-11-30 | Amgen Inc | Derivati benzizotiazola, izotiazolo[3,4-b]piridina, hinazolina, ftalazina, pirido[2,3-d]piridazina i pirido[2,3-d]pirimidina kao kras g12c inhibitori za tretman raka pluća, pankreasa ili debelog creva |
JOP20190272A1 (ar) | 2017-05-22 | 2019-11-21 | Amgen Inc | مثبطات kras g12c وطرق لاستخدامها |
MX2020002502A (es) | 2017-09-08 | 2020-07-20 | Amgen Inc | Inhibidores de kras g12c y metodos para utilizarlos. |
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JP7377679B2 (ja) | 2018-11-19 | 2023-11-10 | アムジエン・インコーポレーテツド | がん治療のためのkrasg12c阻害剤及び1種以上の薬学的に活性な追加の薬剤を含む併用療法 |
JP7454572B2 (ja) | 2018-11-19 | 2024-03-22 | アムジエン・インコーポレーテツド | Kras g12c阻害剤及びその使用方法 |
JP2022514268A (ja) | 2018-12-20 | 2022-02-10 | アムジエン・インコーポレーテツド | Kif18a阻害剤 |
ES2997190T3 (en) | 2018-12-20 | 2025-02-14 | Amgen Inc | Heteroaryl amides useful as kif18a inhibitors |
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-
2000
- 2000-06-07 DE DE60027564T patent/DE60027564T3/de not_active Expired - Lifetime
- 2000-06-07 WO PCT/US2000/015706 patent/WO2000075323A1/en active IP Right Grant
- 2000-06-07 ES ES00938207T patent/ES2262518T5/es not_active Expired - Lifetime
- 2000-06-07 IL IL14648200A patent/IL146482A0/xx unknown
- 2000-06-07 EP EP00938207A patent/EP1187918B9/de not_active Expired - Lifetime
- 2000-06-07 NZ NZ516258A patent/NZ516258A/xx not_active IP Right Cessation
- 2000-06-07 DK DK00938207T patent/DK1187918T4/da active
- 2000-06-07 JP JP2001502586A patent/JP4587626B2/ja not_active Expired - Fee Related
- 2000-06-07 AT AT00938207T patent/ATE324444T1/de not_active IP Right Cessation
- 2000-06-07 CA CA002374851A patent/CA2374851A1/en not_active Abandoned
- 2000-06-07 US US09/590,656 patent/US6413932B1/en not_active Expired - Fee Related
- 2000-06-07 PT PT00938207T patent/PT1187918E/pt unknown
- 2000-06-07 AU AU53282/00A patent/AU783960B2/en not_active Ceased
-
2001
- 2001-11-14 IL IL146482A patent/IL146482A/en not_active IP Right Cessation
-
2006
- 2006-05-02 US US11/416,613 patent/US20070025993A1/en not_active Abandoned
- 2006-07-07 CY CY20061100953T patent/CY1105078T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
JP2003501090A (ja) | 2003-01-14 |
IL146482A (en) | 2010-11-30 |
PT1187918E (pt) | 2006-08-31 |
WO2000075323A1 (en) | 2000-12-14 |
ES2262518T5 (es) | 2009-05-08 |
EP1187918B1 (de) | 2006-04-26 |
US20070025993A1 (en) | 2007-02-01 |
DE60027564T2 (de) | 2007-05-10 |
EP1187918B2 (de) | 2009-01-14 |
CA2374851A1 (en) | 2000-12-14 |
ES2262518T3 (es) | 2006-12-01 |
CY1105078T1 (el) | 2009-11-04 |
DE60027564T3 (de) | 2009-07-23 |
IL146482A0 (en) | 2002-07-25 |
JP4587626B2 (ja) | 2010-11-24 |
EP1187918A1 (de) | 2002-03-20 |
DK1187918T3 (da) | 2006-08-21 |
AU5328200A (en) | 2000-12-28 |
EP1187918B9 (de) | 2009-08-19 |
DK1187918T4 (da) | 2009-02-23 |
AU783960B2 (en) | 2006-01-05 |
US6413932B1 (en) | 2002-07-02 |
NZ516258A (en) | 2004-02-27 |
ATE324444T1 (de) | 2006-05-15 |
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Representative=s name: MEISSNER, BOLTE & PARTNER GBR, 80538 MUENCHEN |
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8366 | Restricted maintained after opposition proceedings |