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DE60017156D1 - Feste lipidformulierung enthaltend lipasehemmer und fettsäureester von polyolen - Google Patents

Feste lipidformulierung enthaltend lipasehemmer und fettsäureester von polyolen

Info

Publication number
DE60017156D1
DE60017156D1 DE60017156T DE60017156T DE60017156D1 DE 60017156 D1 DE60017156 D1 DE 60017156D1 DE 60017156 T DE60017156 T DE 60017156T DE 60017156 T DE60017156 T DE 60017156T DE 60017156 D1 DE60017156 D1 DE 60017156D1
Authority
DE
Germany
Prior art keywords
hemmer
polyols
fatty acid
acid esters
formulation containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60017156T
Other languages
English (en)
Other versions
DE60017156T2 (de
Inventor
Smidt Christiaan De
Paul Hadvary
Hans Lengsfeld
Marcel Schmid
Macfarland Small
Hans Steffen
Joseph Tardio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8238989&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60017156(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of DE60017156D1 publication Critical patent/DE60017156D1/de
Publication of DE60017156T2 publication Critical patent/DE60017156T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Obesity (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
DE60017156T 1999-09-13 2000-09-11 Feste lipidformulierung enthaltend lipasehemmer und fettsäureester von polyolen Expired - Lifetime DE60017156T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP99118179 1999-09-13
EP99118179 1999-09-13
PCT/EP2000/008857 WO2001019378A2 (en) 1999-09-13 2000-09-11 Solid lipid formulations comprising an inhibitor of lipases and a fatty acid ester of polyols

Publications (2)

Publication Number Publication Date
DE60017156D1 true DE60017156D1 (de) 2005-02-03
DE60017156T2 DE60017156T2 (de) 2006-01-05

Family

ID=8238989

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60017156T Expired - Lifetime DE60017156T2 (de) 1999-09-13 2000-09-11 Feste lipidformulierung enthaltend lipasehemmer und fettsäureester von polyolen

Country Status (36)

Country Link
US (1) US6703369B1 (de)
EP (1) EP1216048B1 (de)
JP (1) JP4217017B2 (de)
KR (1) KR100523879B1 (de)
CN (1) CN1197554C (de)
AR (1) AR025609A1 (de)
AT (1) ATE285783T1 (de)
AU (1) AU769016B2 (de)
BR (1) BRPI0013940B1 (de)
CA (1) CA2383036C (de)
CO (1) CO5210857A1 (de)
CZ (1) CZ301844B6 (de)
DE (1) DE60017156T2 (de)
EG (1) EG24225A (de)
ES (1) ES2233444T3 (de)
GC (1) GC0000259A (de)
HK (1) HK1049798B (de)
HR (1) HRP20020206B1 (de)
HU (1) HU229037B1 (de)
IL (2) IL148570A0 (de)
JO (1) JO2300B1 (de)
MA (1) MA26817A1 (de)
ME (1) ME00675B (de)
MX (1) MXPA02002662A (de)
MY (1) MY127430A (de)
NO (1) NO328889B1 (de)
NZ (1) NZ517396A (de)
PE (1) PE20010661A1 (de)
PL (1) PL199869B1 (de)
PT (1) PT1216048E (de)
RS (1) RS50373B (de)
RU (1) RU2248218C2 (de)
SI (1) SI1216048T1 (de)
TR (1) TR200200605T2 (de)
WO (1) WO2001019378A2 (de)
ZA (1) ZA200201249B (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR025609A1 (es) * 1999-09-13 2002-12-04 Hoffmann La Roche Formulaciones lipidas solidas
SI1307264T1 (en) 2000-07-28 2005-02-28 F. Hoffmann-La Roche Ag New pharmaceutical composition
US6730319B2 (en) 2001-06-06 2004-05-04 Hoffmann-La Roche Inc. Pharmaceutical compositions having depressed melting points
US20030027786A1 (en) * 2001-06-06 2003-02-06 Karsten Maeder Lipase inhibiting composition
DE10251963A1 (de) * 2002-11-08 2004-05-19 Lts Lohmann Therapie-Systeme Ag Transmucosale pharmazeutische Darreichungsform
US8372430B2 (en) 2002-12-17 2013-02-12 The Procter & Gamble Company Compositions, methods, and kits useful for the alleviation of gastrointestinal effects
WO2004078164A1 (en) * 2003-03-04 2004-09-16 Nostrum Pharmaceuticals, Inc. Control release formulation containing a hydrophobic material as the sustained release agent
FI20045076L (fi) * 2004-03-15 2005-09-16 Bioferme Oy Funktionaalinen elintarvike
WO2006046623A1 (ja) * 2004-10-25 2006-05-04 Japan Tobacco Inc. 溶解性及び安定性の改善された固形製剤及びその製造方法
KR100669497B1 (ko) * 2005-08-17 2007-01-16 보람제약주식회사 안정성과 용출률이 뛰어난 약리학적 조성물 및 그 제조방법
US20070148245A1 (en) * 2005-12-22 2007-06-28 Ilan Zalit Compressed solid dosage forms with drugs of low solubility and process for making the same
EP1808163A1 (de) * 2005-12-22 2007-07-18 Teva Pharmaceutical Industries Ltd. Komprimierte feste Verabreichungsformen enthaltend Wirkstoffe mit niedriger Löslichkeit und Verfahren zur Herstellung derselben
CA2626234A1 (en) * 2005-12-22 2007-06-28 Teva Pharmaceutical Industries Ltd. Compressed solid dosage forms with drugs of low solubility and process for making the same
KR101252635B1 (ko) 2006-04-20 2013-04-10 (주)아모레퍼시픽 리파아제 저해제 및 친유성 오일흡수제를 포함하는 약학조성물 및 이로부터 제조된 경구 투여용 제제
KR100903504B1 (ko) * 2007-05-18 2009-06-17 강태용 비라칸사스 열매 추출물질을 포함하는 기능식품 및 체중 감소제
JP2010536798A (ja) * 2007-08-17 2010-12-02 テバ ファーマシューティカル インダストリーズ リミティド 難溶性薬物の生体利用率を制御するための方法及び組成物
ES2350798T3 (es) * 2007-09-12 2011-01-27 Mader S.R.L. Composiciones farmacéuticas para uso oral para tratar a pacientes afectados por la obesidad.
PL216542B1 (pl) 2008-03-20 2014-04-30 Zakłady Farmaceutyczne POLPHARMA Spółka Akcyjna Sposób wytwarzania stabilnej kompozycji orlistatu w postaci kapsułkowanego proszku
US8309107B2 (en) 2008-10-06 2012-11-13 Banner Pharmacaps, Inc. Stable solutions of orlistat for pharmaceutical dosage forms
BRPI0901602B8 (pt) 2009-04-03 2021-05-25 Ems S/A formulação farmacêuticas
UA107369C2 (en) 2010-02-01 2014-12-25 Lab Bago S A Pharmaceutical composition with anti-obesity activity comprising a premixture of pure orlistat and preparation process
EP2486805A1 (de) * 2011-02-11 2012-08-15 Puratos N.V. Bei Raumtemperatur aufschlagbare Emulsion
PL2671455T3 (pl) * 2011-04-14 2017-10-31 J Oil Mills Inc Frakcjonowany olej palmowy oraz kompozycja oleju i produkt spożywczy ją zawierający
CN102552168B (zh) * 2012-01-31 2013-08-07 杭州华东医药集团生物工程研究所有限公司 一种含有奥利司他的药物组合物及其制备方法
GB2501535A (en) 2012-04-26 2013-10-30 Sony Corp Chrominance Processing in High Efficiency Video Codecs
MX382986B (es) * 2012-05-31 2025-03-13 Repros Therapeutics Inc El uso de una cápsula mucoadherente que comprende pululano y cdb-2914 para el tratamiento de un trastorno dependiente de la progesterona
WO2015063039A1 (en) * 2013-10-28 2015-05-07 Nestec S.A. Monoacylglycerols for use in conjunction with a lipase inhibitor and/or diets low in fat and/or calories
CN115105476B (zh) * 2021-03-23 2023-11-14 山东新时代药业有限公司 一种奥利司他冻干口服制剂及其制备工艺

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1247547A (en) * 1983-06-22 1988-12-28 Paul Hadvary Leucine derivatives
FR2710264B1 (fr) * 1993-09-21 1995-12-08 Rocher Yves Biolog Vegetale Utilisation pour le traitement des peaux mixtes d'une quantité efficace de substances actives.
WO1998024607A1 (en) * 1996-12-04 1998-06-11 Pincott James S Process and apparatus for making crumb rubber from scrap tyres
ZA98753B (en) 1997-02-05 1998-08-05 Hoffmann La Roche Use of gastrointestinal lipase inhibitors
US6004996A (en) 1997-02-05 1999-12-21 Hoffman-La Roche Inc. Tetrahydrolipstatin containing compositions
US6267952B1 (en) 1998-01-09 2001-07-31 Geltex Pharmaceuticals, Inc. Lipase inhibiting polymers
DE69916288T2 (de) * 1998-08-14 2005-03-24 F. Hoffmann-La Roche Ag Lipasehemmer und chitosan enthaltende arzneimittel
PT1105122E (pt) 1998-08-14 2005-08-31 Hoffmann La Roche Composicoes farmaceuticas que contem inibidores de lipase
AR025609A1 (es) * 1999-09-13 2002-12-04 Hoffmann La Roche Formulaciones lipidas solidas

Also Published As

Publication number Publication date
RU2002107450A (ru) 2004-01-10
CO5210857A1 (es) 2002-10-30
MXPA02002662A (es) 2002-07-30
PT1216048E (pt) 2005-04-29
BR0013940A (pt) 2002-05-14
TR200200605T2 (tr) 2002-08-21
PE20010661A1 (es) 2001-06-25
ES2233444T3 (es) 2005-06-16
MEP90908A (en) 2011-12-20
MA26817A1 (fr) 2004-12-20
DE60017156T2 (de) 2006-01-05
JO2300B1 (en) 2005-09-12
IL148570A0 (en) 2002-09-12
CZ20021277A3 (cs) 2003-04-16
GC0000259A (en) 2006-11-01
CN1197554C (zh) 2005-04-20
CA2383036A1 (en) 2001-03-22
NZ517396A (en) 2003-10-31
AU7517700A (en) 2001-04-17
HRP20020206B1 (en) 2011-02-28
HK1049798A1 (en) 2003-05-30
EP1216048B1 (de) 2004-12-29
PL356154A1 (en) 2004-06-14
JP2003509373A (ja) 2003-03-11
IL148570A (en) 2007-03-08
KR20020060177A (ko) 2002-07-16
YU13602A (sh) 2006-01-16
HUP0202762A2 (hu) 2003-01-28
CA2383036C (en) 2006-01-10
MY127430A (en) 2006-11-30
RU2248218C2 (ru) 2005-03-20
WO2001019378A2 (en) 2001-03-22
CZ301844B6 (cs) 2010-07-07
KR100523879B1 (ko) 2005-10-26
ME00675B (me) 2011-12-20
CN1373659A (zh) 2002-10-09
AR025609A1 (es) 2002-12-04
NO20021205D0 (no) 2002-03-12
EP1216048A2 (de) 2002-06-26
PL199869B1 (pl) 2008-11-28
ATE285783T1 (de) 2005-01-15
JP4217017B2 (ja) 2009-01-28
BRPI0013940B1 (pt) 2016-06-21
ZA200201249B (en) 2003-07-30
HUP0202762A3 (en) 2005-04-28
HRP20020206A2 (en) 2004-04-30
NO328889B1 (no) 2010-06-07
WO2001019378A3 (en) 2001-05-10
AU769016B2 (en) 2004-01-15
NO20021205L (no) 2002-03-12
SI1216048T1 (en) 2005-06-30
RS50373B (sr) 2009-11-10
HK1049798B (zh) 2005-08-05
HU229037B1 (en) 2013-07-29
US6703369B1 (en) 2004-03-09
EG24225A (en) 2008-11-10

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Legal Events

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8364 No opposition during term of opposition