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DE69708284D1 - Wässrige suspension von 9-hydroxyrisperidon-fettsäureester - Google Patents

Wässrige suspension von 9-hydroxyrisperidon-fettsäureester

Info

Publication number
DE69708284D1
DE69708284D1 DE69708284T DE69708284T DE69708284D1 DE 69708284 D1 DE69708284 D1 DE 69708284D1 DE 69708284 T DE69708284 T DE 69708284T DE 69708284 T DE69708284 T DE 69708284T DE 69708284 D1 DE69708284 D1 DE 69708284D1
Authority
DE
Germany
Prior art keywords
fatty acid
acid ester
aqueous suspension
hydroxyrisperidone fatty
hydroxyrisperidone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69708284T
Other languages
English (en)
Other versions
DE69708284T2 (de
Inventor
Marc Karel Jozef Francois
Roger Carolus August Embrechts
Herman Karel Borghijs
Johan Monbaliu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8224016&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69708284(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Application granted granted Critical
Publication of DE69708284D1 publication Critical patent/DE69708284D1/de
Publication of DE69708284T2 publication Critical patent/DE69708284T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE69708284T 1996-05-20 1997-05-12 Wässrige suspension von 9-hydroxyrisperidon-fettsäureester Expired - Lifetime DE69708284T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96201429 1996-05-20
PCT/EP1997/002504 WO1997044039A1 (en) 1996-05-20 1997-05-12 Aqueous suspensions of 9-hydroxyrisperidone fatty acid esters

Publications (2)

Publication Number Publication Date
DE69708284D1 true DE69708284D1 (de) 2001-12-20
DE69708284T2 DE69708284T2 (de) 2002-07-25

Family

ID=8224016

Family Applications (2)

Application Number Title Priority Date Filing Date
DE201112100027 Pending DE122011100027I1 (de) 1996-05-20 1997-05-12 Wassrige suspension von 9-hydroxyrisperidon-fettsaureester.
DE69708284T Expired - Lifetime DE69708284T2 (de) 1996-05-20 1997-05-12 Wässrige suspension von 9-hydroxyrisperidon-fettsäureester

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE201112100027 Pending DE122011100027I1 (de) 1996-05-20 1997-05-12 Wassrige suspension von 9-hydroxyrisperidon-fettsaureester.

Country Status (38)

Country Link
US (1) US6077843A (de)
EP (1) EP0904081B1 (de)
JP (1) JP3274687B2 (de)
KR (1) KR100358373B1 (de)
CN (1) CN1093762C (de)
AR (1) AR007194A1 (de)
AT (1) ATE208619T1 (de)
AU (1) AU715572B2 (de)
BG (1) BG62684B1 (de)
BR (1) BR9706824B8 (de)
CA (1) CA2236691C (de)
CY (2) CY2270B1 (de)
CZ (1) CZ291284B6 (de)
DE (2) DE122011100027I1 (de)
DK (1) DK0904081T3 (de)
EA (1) EA000536B1 (de)
EE (1) EE03594B1 (de)
ES (1) ES2167745T3 (de)
FR (1) FR11C0035I2 (de)
HK (1) HK1017852A1 (de)
HR (1) HRP970276B1 (de)
HU (2) HU224025B1 (de)
ID (1) ID16927A (de)
IL (1) IL124551A (de)
LU (1) LU91842I2 (de)
MX (1) MX9804816A (de)
MY (1) MY126302A (de)
NO (2) NO315931B1 (de)
NZ (1) NZ330369A (de)
PL (1) PL188309B1 (de)
PT (1) PT904081E (de)
SI (1) SI0904081T1 (de)
SK (1) SK284013B6 (de)
TR (1) TR199800923T2 (de)
TW (1) TW487572B (de)
UA (1) UA61898C2 (de)
WO (1) WO1997044039A1 (de)
ZA (1) ZA974331B (de)

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US7666445B2 (en) * 2000-10-20 2010-02-23 The Trustees Of The University Of Pennsylvania Polymer-based surgically implantable haloperidol delivery systems and methods for their production and use
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US8221778B2 (en) 2005-01-12 2012-07-17 The Trustees Of The University Of Pennsylvania Drug-containing implants and methods of use thereof
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Also Published As

Publication number Publication date
SK284013B6 (sk) 2004-08-03
HRP970276B1 (en) 2002-04-30
HU224025B1 (hu) 2005-05-30
JP3274687B2 (ja) 2002-04-15
NZ330369A (en) 2000-04-28
HK1017852A1 (en) 1999-12-03
EP0904081B1 (de) 2001-11-14
CN1206347A (zh) 1999-01-27
ID16927A (id) 1997-11-20
LU91842I2 (fr) 2011-09-20
TW487572B (en) 2002-05-21
HRP970276A2 (en) 1998-04-30
BG102443A (en) 1999-06-30
FR11C0035I2 (fr) 2013-08-16
PL327995A1 (en) 1999-01-04
CY2011011I2 (el) 2016-12-14
NO2011015I1 (no) 2011-09-19
NO981984D0 (no) 1998-04-30
BR9706824B8 (pt) 2015-02-18
EE9800136A (et) 1998-10-15
KR100358373B1 (ko) 2003-02-11
EP0904081A1 (de) 1999-03-31
HUS1100013I1 (hu) 2017-03-28
DE122011100027I1 (de) 2011-11-17
CY2270B1 (en) 2003-07-04
SK62098A3 (en) 2000-04-10
TR199800923T2 (xx) 1999-09-21
BR9706824A (pt) 1999-03-23
IL124551A0 (en) 1998-12-06
CA2236691C (en) 2007-01-02
MX9804816A (es) 1998-10-31
WO1997044039A1 (en) 1997-11-27
NO981984L (no) 1998-11-19
EE03594B1 (et) 2002-02-15
SI0904081T1 (en) 2002-04-30
AR007194A1 (es) 1999-10-13
CN1093762C (zh) 2002-11-06
MY126302A (en) 2006-09-29
CZ140198A3 (cs) 1999-04-14
CZ291284B6 (cs) 2003-01-15
FR11C0035I1 (de) 2011-07-10
CY2011011I1 (el) 2016-12-14
EA199800531A1 (ru) 1998-12-24
CA2236691A1 (en) 1997-11-27
ES2167745T3 (es) 2002-05-16
US6077843A (en) 2000-06-20
AU715572B2 (en) 2000-02-03
ZA974331B (en) 1998-11-19
ATE208619T1 (de) 2001-11-15
DE69708284T2 (de) 2002-07-25
IL124551A (en) 2001-08-26
PT904081E (pt) 2002-04-29
AU2955997A (en) 1997-12-09
DK0904081T3 (da) 2002-02-25
HUP9901319A2 (hu) 1999-08-30
HUP9901319A3 (en) 1999-11-29
EA000536B1 (ru) 1999-10-28
BG62684B1 (bg) 2000-05-31
PL188309B1 (pl) 2005-01-31
KR19990067603A (ko) 1999-08-25
JP2000513718A (ja) 2000-10-17
NO315931B1 (no) 2003-11-17
NO2011015I2 (no) 2013-03-11
UA61898C2 (en) 2003-12-15

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