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DE60009929D1 - Glucopyranosyloxypyrazol-derivate, diese enthaltende arzneimittel und zwischenprodukte zu deren herstellung - Google Patents

Glucopyranosyloxypyrazol-derivate, diese enthaltende arzneimittel und zwischenprodukte zu deren herstellung

Info

Publication number
DE60009929D1
DE60009929D1 DE60009929T DE60009929T DE60009929D1 DE 60009929 D1 DE60009929 D1 DE 60009929D1 DE 60009929 T DE60009929 T DE 60009929T DE 60009929 T DE60009929 T DE 60009929T DE 60009929 D1 DE60009929 D1 DE 60009929D1
Authority
DE
Germany
Prior art keywords
group
lower alkyl
products
production
glucopyranosyloxypyrazole derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60009929T
Other languages
English (en)
Other versions
DE60009929T2 (de
Inventor
Hideki Fujikura
Toshihiro Nishimura
Kenji Katsuno
Masahiro Hiratochi
Akira Iyobe
Minoru Fujioka
Masayuki Isaji
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kissei Pharmaceutical Co Ltd
Original Assignee
Kissei Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=17153879&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60009929(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kissei Pharmaceutical Co Ltd filed Critical Kissei Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE60009929D1 publication Critical patent/DE60009929D1/de
Publication of DE60009929T2 publication Critical patent/DE60009929T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18—One oxygen or sulfur atom
    • C07D231/20—One oxygen atom attached in position 3 or 5
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Obesity (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE60009929T 1999-08-31 2000-08-24 Glucopyranosyloxypyrazol-derivate, diese enthaltende arzneimittel und zwischenprodukte zu deren herstellung Expired - Lifetime DE60009929T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP24680099 1999-08-31
JP24680099 1999-08-31
PCT/JP2000/005678 WO2001016147A1 (fr) 1999-08-31 2000-08-24 Derives de glucopyranosyloxypyrazole, compositions medicinales renfermant lesdits derives et produits intermediaires obtenus au cours de leur production

Publications (2)

Publication Number Publication Date
DE60009929D1 true DE60009929D1 (de) 2004-05-19
DE60009929T2 DE60009929T2 (de) 2005-03-31

Family

ID=17153879

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60009929T Expired - Lifetime DE60009929T2 (de) 1999-08-31 2000-08-24 Glucopyranosyloxypyrazol-derivate, diese enthaltende arzneimittel und zwischenprodukte zu deren herstellung

Country Status (29)

Country Link
US (4) US6972283B2 (de)
EP (1) EP1213296B1 (de)
JP (1) JP3989730B2 (de)
KR (1) KR100591585B1 (de)
CN (1) CN1145635C (de)
AT (1) ATE264337T1 (de)
AU (1) AU782330B2 (de)
BG (1) BG65388B1 (de)
BR (1) BRPI0013667B8 (de)
CA (1) CA2382480C (de)
CZ (1) CZ303372B6 (de)
DE (1) DE60009929T2 (de)
DK (1) DK1213296T3 (de)
ES (1) ES2216937T3 (de)
HK (1) HK1050369A1 (de)
HU (1) HU229581B1 (de)
IL (2) IL148384A0 (de)
MX (1) MXPA02002271A (de)
NO (1) NO322703B1 (de)
NZ (1) NZ517439A (de)
PL (1) PL203124B1 (de)
PT (1) PT1213296E (de)
RU (1) RU2232767C2 (de)
SK (1) SK286600B6 (de)
TR (1) TR200201082T2 (de)
TW (1) TW579378B (de)
UA (1) UA71994C2 (de)
WO (1) WO2001016147A1 (de)
ZA (1) ZA200201991B (de)

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JP4591781B2 (ja) * 2000-11-02 2010-12-01 味の素株式会社 新規ピラゾール誘導体及びそれらを含有する糖尿病治療薬
ATE455785T1 (de) * 2000-11-02 2010-02-15 Ajinomoto Kk Neue pyrazolderivate und diese enthaltende mittel gegen diabetes
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KR100882179B1 (ko) * 2001-06-20 2009-02-06 깃세이 야쿠힌 고교 가부시키가이샤 함질소 복소환 유도체, 그것을 함유하는 의약 조성물, 그의약 용도 및 그 제조 중간체
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