DE3852221D1 - Tierische Zelle mit darin eingeführtem antigenem Protein. - Google Patents
Tierische Zelle mit darin eingeführtem antigenem Protein.Info
- Publication number
- DE3852221D1 DE3852221D1 DE3852221T DE3852221T DE3852221D1 DE 3852221 D1 DE3852221 D1 DE 3852221D1 DE 3852221 T DE3852221 T DE 3852221T DE 3852221 T DE3852221 T DE 3852221T DE 3852221 D1 DE3852221 D1 DE 3852221D1
- Authority
- DE
- Germany
- Prior art keywords
- cells
- modified
- aids
- virus
- erythrocytes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 210000004102 animal cell Anatomy 0.000 title 1
- 230000000890 antigenic effect Effects 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 210000004027 cell Anatomy 0.000 abstract 6
- 210000003743 erythrocyte Anatomy 0.000 abstract 3
- 208000030507 AIDS Diseases 0.000 abstract 2
- 210000000805 cytoplasm Anatomy 0.000 abstract 2
- 108010041397 CD4 Antigens Proteins 0.000 abstract 1
- 241000725303 Human immunodeficiency virus Species 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 210000000170 cell membrane Anatomy 0.000 abstract 1
- 229940127089 cytotoxic agent Drugs 0.000 abstract 1
- 239000002254 cytotoxic agent Substances 0.000 abstract 1
- 231100000599 cytotoxic agent Toxicity 0.000 abstract 1
- 239000002502 liposome Substances 0.000 abstract 1
- 210000004698 lymphocyte Anatomy 0.000 abstract 1
- 210000000865 mononuclear phagocyte system Anatomy 0.000 abstract 1
- 238000011176 pooling Methods 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/18—Erythrocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/168—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5063—Compounds of unknown constitution, e.g. material from plants or animals
- A61K9/5068—Cell membranes or bacterial membranes enclosing drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/5432—Liposomes or microcapsules
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/554—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being a biological cell or cell fragment, e.g. bacteria, yeast cells
- G01N33/555—Red blood cell
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
- G01N33/56988—HIV or HTLV
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Urology & Nephrology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Nanotechnology (AREA)
- Biophysics (AREA)
- Botany (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Developmental Biology & Embryology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Crystallography & Structural Chemistry (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6828887A | 1987-06-30 | 1987-06-30 | |
US19744588A | 1988-05-27 | 1988-05-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3852221D1 true DE3852221D1 (de) | 1995-01-12 |
DE3852221T2 DE3852221T2 (de) | 1995-04-06 |
Family
ID=26748809
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3852221T Expired - Fee Related DE3852221T2 (de) | 1987-06-30 | 1988-06-14 | Tierische Zelle mit darin eingeführtem antigenem Protein. |
Country Status (9)
Country | Link |
---|---|
US (1) | US5677176A (de) |
EP (1) | EP0298280B1 (de) |
JP (2) | JP2728166B2 (de) |
AT (1) | ATE114476T1 (de) |
AU (2) | AU1821988A (de) |
CA (1) | CA1327332C (de) |
DE (1) | DE3852221T2 (de) |
ES (1) | ES2067457T3 (de) |
IL (1) | IL86650A0 (de) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5310654A (en) * | 1985-07-31 | 1994-05-10 | The Board Of Trustees Of The Leland Stanford Junior University | Method for determining virulence of Yersinia |
US5236835A (en) * | 1988-10-05 | 1993-08-17 | Hapgood, C.V. | Electro insertion of proteins into red cell membranes |
CA1327174C (en) * | 1988-10-05 | 1994-02-22 | Youssef Mouneimne | Electro-insertion of proteins into animal cell membranes |
KR910700291A (ko) * | 1988-12-22 | 1991-03-14 | 리챠드 지. 워터맨 | 헤테로사이클릭 중합체의 개선된 합성방법 |
JP3414395B2 (ja) * | 1990-10-19 | 2003-06-09 | ユニバーシティー オブ フロリダ | 人工的に製造したウィルスのエンベロープ |
US5252348A (en) * | 1990-10-19 | 1993-10-12 | Univ. Of Florida Research Foundation, Inc. | Artificial viral envelopes |
US5753258A (en) * | 1990-10-19 | 1998-05-19 | University Of Florida | Artificial viral envelopes |
PL296382A1 (en) * | 1991-02-02 | 1993-11-02 | Nika Health Products Ltd Li Li | Artificial membrane beads containing functionally active peptides responsible for fusion as a drug administering system |
ES2109260T3 (es) * | 1991-06-14 | 1998-01-16 | Europ Communities | Eritrocitos transformados, procedimiento para prepararlos y su utilizacion en composiciones farmaceuticas. |
GB9219562D0 (en) | 1992-03-11 | 1992-10-28 | Prendergast Kennet F | Anti-viral peptides |
DE69329145D1 (de) * | 1992-03-11 | 2000-09-07 | Kenneth Francis Prendergast | Anti-virale Fusionspeptide |
AU5014393A (en) * | 1992-08-13 | 1994-03-15 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | The use of cd4 plasma membrane vesicles (pmv) as a therapeutic agent for aids |
CA2144767A1 (en) * | 1992-09-22 | 1994-03-31 | Guerard W. Byrne | Delivery of proteins by intermembrane transfer for preaccommodation of xenogeneic organ transplants and other purposes |
US5840328A (en) * | 1994-01-11 | 1998-11-24 | The Liposome Company, Inc. | Treatment using arachidonic acid metabolite and particulate formulations |
HUT76331A (en) * | 1994-07-15 | 1997-08-28 | Lepetit Spa | Dinucleoside-5',5'-pyrophosphates |
US5591448A (en) * | 1994-11-21 | 1997-01-07 | Tepic; Slobodan | Anti-viral therapeutic composition |
US5834015A (en) * | 1996-09-11 | 1998-11-10 | Albany Medical College | Protein-lipid vesicles and autogenous vaccine comprising the same |
GB9721901D0 (en) | 1997-10-16 | 1997-12-17 | Univ Manchester | Particles |
AU1734600A (en) * | 1998-11-17 | 2000-06-05 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Identification of glycosphingolipids that promote hiv-1 entry into cells |
ATE272391T1 (de) | 1998-12-23 | 2004-08-15 | Idea Ag | Verbesserte formulierung zur topischen, nichtinvasiven anwendung in vivo |
SI1031346T1 (en) | 1999-01-27 | 2002-08-31 | Idea Ag | Noninvasive vaccination through the skin |
ES2173679T3 (es) | 1999-01-27 | 2002-10-16 | Idea Ag | Inmunizacion/transporte transnasal con vehiculos altamente adaptables. |
EP1921451A3 (de) * | 2001-05-22 | 2008-05-28 | Cygene, Inc. | Komplement-vermittelte Assays für In-vivo- und In-vitro-Verfahren |
WO2003034074A1 (en) * | 2001-10-16 | 2003-04-24 | Kiwi Ingenuity Limited | Sensitivity controls for blood serology prepared from modified cells |
US20050032113A1 (en) * | 2003-07-17 | 2005-02-10 | Mitsubishi Pharma Corporation | Membrane protein library for proteome analysis and method for preparing same |
CN102046151A (zh) * | 2008-03-26 | 2011-05-04 | 牛津大学 | 靶向内质网的脂质体 |
US20110070153A1 (en) * | 2008-08-13 | 2011-03-24 | Searete, Llc, A Limited Liability Corporation Of The State Of Delaware | Artificial cells |
US8211656B2 (en) | 2008-08-13 | 2012-07-03 | The Invention Science Fund I, Llc | Biological targeting compositions and methods of using the same |
US20100042072A1 (en) * | 2008-08-13 | 2010-02-18 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Biological targeting compositions and methods of using the same |
US20100040546A1 (en) * | 2008-08-13 | 2010-02-18 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Biological targeting compositions and methods of using the same |
WO2011044369A1 (en) | 2009-10-08 | 2011-04-14 | Otsuka Pharmaceutical Co., Ltd. | An immunoactivation blood perfusion filter for the treatment of malignant tumors |
AU2014348683B2 (en) | 2013-11-18 | 2020-11-05 | Rubius Therapeutics, Inc. | Synthetic membrane-receiver complexes |
KR20170005801A (ko) | 2014-04-01 | 2017-01-16 | 루비우스 테라퓨틱스, 아이엔씨. | 면역조절을 위한 방법 및 조성물 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA806506B (en) * | 1979-11-01 | 1981-09-30 | Bio Response Inc | A method for production of monoclonal antibodies |
DE3218121A1 (de) * | 1982-05-14 | 1983-11-17 | Leskovar, Peter, Dr.-Ing., 8000 München | Arzneimittel zur tumorbehandlung |
FR2564319A1 (fr) * | 1984-05-21 | 1985-11-22 | Inst Nat Sante Rech Med | Nouvelles compositions de liposomes dotees d'une action specifique vis-a-vis de la proliferation de cellules donnees |
US5236835A (en) * | 1988-10-05 | 1993-08-17 | Hapgood, C.V. | Electro insertion of proteins into red cell membranes |
-
1988
- 1988-06-07 IL IL86650A patent/IL86650A0/xx not_active IP Right Cessation
- 1988-06-14 AT AT88109455T patent/ATE114476T1/de not_active IP Right Cessation
- 1988-06-14 DE DE3852221T patent/DE3852221T2/de not_active Expired - Fee Related
- 1988-06-14 ES ES88109455T patent/ES2067457T3/es not_active Expired - Lifetime
- 1988-06-14 EP EP88109455A patent/EP0298280B1/de not_active Expired - Lifetime
- 1988-06-21 AU AU18219/88A patent/AU1821988A/en not_active Abandoned
- 1988-06-27 CA CA000570526A patent/CA1327332C/en not_active Expired - Fee Related
- 1988-06-30 JP JP63164103A patent/JP2728166B2/ja not_active Expired - Fee Related
-
1992
- 1992-07-02 AU AU19426/92A patent/AU662154B2/en not_active Ceased
-
1995
- 1995-03-15 US US08/404,372 patent/US5677176A/en not_active Expired - Fee Related
-
1997
- 1997-05-26 JP JP9134805A patent/JP2825804B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ES2067457T3 (es) | 1995-04-01 |
EP0298280B1 (de) | 1994-11-30 |
JPH01124382A (ja) | 1989-05-17 |
AU1821988A (en) | 1989-04-27 |
JPH1072368A (ja) | 1998-03-17 |
AU1942692A (en) | 1992-09-24 |
EP0298280A2 (de) | 1989-01-11 |
IL86650A0 (en) | 1988-11-30 |
AU662154B2 (en) | 1995-08-24 |
US5677176A (en) | 1997-10-14 |
ATE114476T1 (de) | 1994-12-15 |
JP2825804B2 (ja) | 1998-11-18 |
JP2728166B2 (ja) | 1998-03-18 |
DE3852221T2 (de) | 1995-04-06 |
CA1327332C (en) | 1994-03-01 |
EP0298280A3 (en) | 1990-05-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE3852221D1 (de) | Tierische Zelle mit darin eingeführtem antigenem Protein. | |
ES8503951A1 (es) | Un procedimiento para preparar un complejo inmunogenico que contiene proteinas o peptidos antigenicos | |
ES2091861T3 (es) | Proteinas antigenicas y vacunas que las contienen para la prevencion de la coccidiosis. | |
IL89701A0 (en) | Recombinant retroviruses,method for the production thereof and pharmaceutical composition containing the same | |
ES2099066T3 (es) | Antigenos a partir de adn sintetico derivado del virus de la inmunodeficiencia humana (hiv-1). | |
DE69033700D1 (de) | Il-11 aus säugetier | |
EP0158277A3 (de) | Implantierbare Zubereitungen von regulatorischen Peptiden mit gesteuerter Freisetzung und Verfahren zur ihrer Herstellung | |
SE8703225L (sv) | Monoklonala antikroppar och peptider anvendbara vid behandling och diagnostisering av hiv-infektioner | |
Wivel et al. | Structural organization of murine intracisternal A particles | |
GR3007031T3 (de) | ||
Sonozaki et al. | The macrophage disappearance reaction: II. Mediation by lymphocytes which lack complement receptors | |
EP0236977A3 (de) | Impfstoffe gegen Rindervirus-Diarrhoe und Schweine-Cholera | |
Hale et al. | Antigen-liposome modification of target cells as a method to alter their susceptibility to lysis by cytotoxic T lymphocytes. | |
RU94040393A (ru) | Синтетические пептиды для вакцины против краснухи | |
DK373489D0 (da) | Rekombinante hybrid-partikler med morphologiske egenskaber svarende til antigenet hbsag og omfattende en immunogen sekvens, der inducerer neutraliserende antistoffer rettet mod hiv-retrovirus eller som kan genkendes af saadanne antistoffer, samt vaccine paa basis af saadanne partikler | |
IT8621230A1 (it) | Policarbonati ramificati contenenti acidi alifatici policarbossilici o loro derivati e procedimento per la loro preparazione | |
AU2190288A (en) | Vector for the expression of proteins of the HIV-2 virus, one of the casual agents of AIDS, cell culture infected or transformed by this vector, proteins obtained, vaccine and antibodies obtained | |
Iwata et al. | Identification of human H‐Y antigen and its testis‐organizing function | |
Van Den Heuvel et al. | Isolation of a bovine plasma fibronectin-containing complex which inhibits the expression of bovine leukemia virus p24 | |
EP0283443A3 (en) | Process for extracting membrane antigens having immunogenic properties from human neoplastic cells and products thereby obtained | |
DK145988D0 (da) | Genteknologisk fremstillet 140 kd-antigen af plasmodium falciparum og dettes anvendelse | |
ES2011679A6 (es) | Procedimiento para la preparacion de polipeptidos sinteticos secuenc iales inmunologicamente activos. | |
Pearse | Structure of coated pits and vesicles | |
JH Humphrey | The Value of Immunological Concepts in Medicine: The Croonian Lecture 1981 | |
Callahan et al. | Rat Cell Surface Antigens: II. Isolation of a Minor Histocompatibility Antigen |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee | ||
8370 | Indication related to discontinuation of the patent is to be deleted | ||
8339 | Ceased/non-payment of the annual fee |