DE19680509T1 - (-)-(3R)-3-Methyl-4-(4-(4-(4pyridyl)piperazin-1-yl)phenoxybuttersäure als Zellaadhäsionsinhibitor - Google Patents

(-)-(3R)-3-Methyl-4-(4-(4-(4pyridyl)piperazin-1-yl)phenoxybuttersäure als Zellaadhäsionsinhibitor

Info

Publication number: DE19680509T1
Authority: DE; Germany
Prior art keywords: 4pyridyl; piperazin; methyl; cell adhesion; adhesion inhibitor
Prior art date: 1995-06-01
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

DE19680509T

Other languages

German (de)

English (en)

Inventor

Stuart Dennett Mills

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Syngenta Ltd

Original Assignee

Zeneca Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-06-01

Filing date

1996-05-28

Publication date

1997-12-04

1995-06-01 Priority claimed from US08/457,538 external-priority patent/US5652242A/en

1995-09-07 Priority claimed from GBGB9518188.9A external-priority patent/GB9518188D0/en

1996-05-28 Application filed by Zeneca Ltd filed Critical Zeneca Ltd

1997-12-04 Publication of DE19680509T1 publication Critical patent/DE19680509T1/de

Status Withdrawn legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Hematology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DE19680509T 1995-06-01 1996-05-28 (-)-(3R)-3-Methyl-4-(4-(4-(4pyridyl)piperazin-1-yl)phenoxybuttersäure als Zellaadhäsionsinhibitor Withdrawn DE19680509T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US08/457,538 US5652242A (en)	1993-03-29	1995-06-01	Heterocyclic derivatives
GBGB9518188.9A GB9518188D0 (en)	1995-09-07	1995-09-07	Optically active derivative
PCT/GB1996/001260 WO1996038416A1 (en)	1995-06-01	1996-05-28	(-)-(3r)-3-methyl-4-{4-[4-(4-pyridyl)piperazin-1-yl]phenoxy} butyric acid as cellular adhesion inhibitor

Publications (1)

Publication Number	Publication Date
DE19680509T1 true DE19680509T1 (de)	1997-12-04

Family

ID=26307696

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE19680509T Withdrawn DE19680509T1 (de)	1995-06-01	1996-05-28	(-)-(3R)-3-Methyl-4-(4-(4-(4pyridyl)piperazin-1-yl)phenoxybuttersäure als Zellaadhäsionsinhibitor

Country Status (31)

Country	Link
EP (1)	EP0796247A1 (sv)
JP (1)	JP2885941B2 (sv)
KR (1)	KR100245957B1 (sv)
AT (1)	AT406675B (sv)
AU (1)	AU710105B2 (sv)
BE (1)	BE1009520A5 (sv)
BR (1)	BR9606409A (sv)
CA (1)	CA2194397A1 (sv)
CH (1)	CH691808A5 (sv)
CZ (1)	CZ26997A3 (sv)
DE (1)	DE19680509T1 (sv)
DK (1)	DK10697A (sv)
ES (1)	ES2137886B1 (sv)
FI (1)	FI970393L (sv)
GB (1)	GB2304340B (sv)
GR (1)	GR1002702B (sv)
HU (1)	HUP9700274A3 (sv)
IE (1)	IE960405A1 (sv)
IL (1)	IL118477A0 (sv)
IT (1)	IT1290839B1 (sv)
LU (1)	LU90008B1 (sv)
MC (1)	MC2418A1 (sv)
MX (1)	MX9700379A (sv)
NL (1)	NL1003243C2 (sv)
NO (1)	NO307460B1 (sv)
NZ (1)	NZ308597A (sv)
PL (1)	PL318440A1 (sv)
SE (1)	SE510812C2 (sv)
SK (1)	SK13097A3 (sv)
TR (1)	TR199700020T1 (sv)
WO (1)	WO1996038416A1 (sv)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0100158A3 (en) *	1982-07-28	1985-03-27	The Upjohn Company	(3-pyridinyl)heteroalkarylalkanols, alkanoic acids and esters
GB8609630D0 (en) *	1986-04-19	1986-05-21	Pfizer Ltd	Anti-arrhythmia agents
AU692439B2 (en) *	1993-03-29	1998-06-11	Zeneca Limited	Heterocyclic compounds as platelet aggregation inhibitors
PT825184E (pt) *	1993-03-29	2001-11-30	Astrazeneca Ab	Derivados heterociclicos como inibidores de agregacao de plaquetas

1996
- 1996-05-28 ES ES009750006A patent/ES2137886B1/es not_active Expired - Fee Related
- 1996-05-28 JP JP8536281A patent/JP2885941B2/ja not_active Expired - Fee Related
- 1996-05-28 MX MX9700379A patent/MX9700379A/es unknown
- 1996-05-28 PL PL96318440A patent/PL318440A1/xx unknown
- 1996-05-28 AU AU58272/96A patent/AU710105B2/en not_active Ceased
- 1996-05-28 CH CH00224/97A patent/CH691808A5/de not_active IP Right Cessation
- 1996-05-28 TR TR97/00020T patent/TR199700020T1/xx unknown
- 1996-05-28 AT AT0900596A patent/AT406675B/de active
- 1996-05-28 DE DE19680509T patent/DE19680509T1/de not_active Withdrawn
- 1996-05-28 KR KR1019970700532A patent/KR100245957B1/ko not_active IP Right Cessation
- 1996-05-28 BR BR9606409A patent/BR9606409A/pt not_active Application Discontinuation
- 1996-05-28 CZ CZ97269A patent/CZ26997A3/cs unknown
- 1996-05-28 HU HU9700274A patent/HUP9700274A3/hu unknown
- 1996-05-28 WO PCT/GB1996/001260 patent/WO1996038416A1/en not_active IP Right Cessation
- 1996-05-28 CA CA002194397A patent/CA2194397A1/en not_active Abandoned
- 1996-05-28 GR GR960100176A patent/GR1002702B/el not_active IP Right Cessation
- 1996-05-28 SK SK130-97A patent/SK13097A3/sk unknown
- 1996-05-28 GB GB9627127A patent/GB2304340B/en not_active Expired - Fee Related
- 1996-05-28 EP EP96919906A patent/EP0796247A1/en not_active Withdrawn
- 1996-05-28 NZ NZ308597A patent/NZ308597A/en unknown
- 1996-05-29 MC MC2347A patent/MC2418A1/xx unknown
- 1996-05-30 IL IL11847796A patent/IL118477A0/xx unknown
- 1996-05-31 NL NL1003243A patent/NL1003243C2/xx not_active IP Right Cessation
- 1996-05-31 IE IE960405A patent/IE960405A1/en not_active IP Right Cessation
- 1996-05-31 BE BE9600491A patent/BE1009520A5/fr not_active IP Right Cessation
- 1996-05-31 IT IT96MI001113A patent/IT1290839B1/it active IP Right Grant
1997
- 1997-01-22 LU LU90008A patent/LU90008B1/fr active
- 1997-01-24 SE SE9700203A patent/SE510812C2/sv not_active IP Right Cessation
- 1997-01-30 FI FI970393A patent/FI970393L/sv unknown
- 1997-01-30 DK DK010697A patent/DK10697A/da not_active Application Discontinuation
- 1997-01-31 NO NO970437A patent/NO307460B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
FI970393A0 (sv)	1997-01-30
BR9606409A (pt)	1997-09-30
AU5827296A (en)	1996-12-18
ES2137886B1 (es)	2000-08-16
SE510812C2 (sv)	1999-06-28
FI970393L (sv)	1997-01-30
IL118477A0 (en)	1996-09-12
GB9627127D0 (en)	1997-02-19
SE9700203D0 (sv)	1997-01-24
JPH09512836A (ja)	1997-12-22
NO307460B1 (no)	2000-04-10
CA2194397A1 (en)	1996-12-05
ITMI961113A1 (it)	1997-12-01
IE960405A1 (en)	1996-12-11
WO1996038416A1 (en)	1996-12-05
AT406675B (de)	2000-07-25
EP0796247A1 (en)	1997-09-24
DK10697A (da)	1997-04-01
HU9700274D0 (en)	1997-04-28
CZ26997A3 (en)	1997-08-13
MC2418A1 (fr)	1997-05-23
NZ308597A (en)	1998-11-25
AU710105B2 (en)	1999-09-16
MX9700379A (es)	1997-04-30
GB2304340A (en)	1997-03-19
GB2304340B (en)	1998-07-29
IT1290839B1 (it)	1998-12-14
NO970437L (no)	1997-02-20
JP2885941B2 (ja)	1999-04-26
ES2137886A1 (es)	1999-12-16
SK13097A3 (en)	1997-08-06
SE9700203L (sv)	1997-01-24
LU90008B1 (fr)	1997-04-16
BE1009520A5 (fr)	1997-04-01
CH691808A5 (de)	2001-10-31
HUP9700274A3 (en)	2000-02-28
HUP9700274A2 (hu)	1999-06-28
KR100245957B1 (ko)	2000-04-01
ATA900596A (de)	1999-12-15
PL318440A1 (en)	1997-06-09
TR199700020T1 (tr)	1997-04-22
NO970437D0 (no)	1997-01-31
GR1002702B (el)	1997-05-22
NL1003243C2 (nl)	1996-12-04
KR970704689A (ko)	1997-09-06
ITMI961113A0 (it)	1996-05-31

Publication	Publication Date	Title
NO980097L (no)	1998-03-11	Celleadhesjonsinhibitorer
ID23668A (id)	2000-05-11	Turunan asam ariloksiarilsulfonilamino hidroksamat
ID21140A (id)	1999-04-29	Metode produksi asam akrilat
DE59601770D1 (de)	1999-06-02	Substituierte quaterrylentetracarbonsäurediimide
DE69522690D1 (de)	2001-10-18	alpha-ketogultarsäure dehydrogenasegen
ATE211131T1 (de)	2002-01-15	Arylsulfonylaminohydroxamsäurederivate
FI973087L (sv)	1997-09-22	Inhibitorer för celladhesion
DE60012883D1 (de)	2004-09-16	2,3,4,5-tetrahydro-1h-[1,4]benzodiazepin-3-hydroxamsäure als matrix metalloproteinaseinhibitoren
ID20807A (id)	1999-03-11	Asam sulfonilaminokarboksilat
DE60041256D1 (de)	2009-02-12	Mono-substituierte 3-propyl-gamma-aminobuttersäure
DE69616892D1 (de)	2001-12-20	Adhäsivbandabgabevorrichtung
DE60011568D1 (de)	2004-07-22	Derivativen von monosacchariden als zelladhäsionshemmer
DE59606674D1 (de)	2001-05-03	Hydroximsäurederivate, verfahren zu ihrer herstellung und ihre verwendung als schädlingsbekämpfungsmittel und fungizide
DE19680509T1 (de)	1997-12-04	(-)-(3R)-3-Methyl-4-(4-(4-(4pyridyl)piperazin-1-yl)phenoxybuttersäure als Zellaadhäsionsinhibitor
EP0671406A3 (en)	1995-11-08	Beta-glycolipid sulphate derivatives as cell adhesion inhibitors.
NO980994D0 (no)	1998-03-06	Substituerte fosfinsyreforbindelser og deres anvendelse som farmasöytika
EE200000239A (et)	2001-08-15	Uued metüleenbisfosfoonhappe derivaadid
KR970006550U (ko)	1997-02-21	모자이크화된 온돌용 판
DE69616661D1 (de)	2001-12-13	Optisch-aktives Monophosphino-Carbonsäurederivat
ITPG950012V0 (it)	1995-04-26	Contromarca (fox room)
DE69612427D1 (de)	2001-05-17	Klebebandabgabegerät
ITPG950005V0 (it)	1995-02-22	Contromarca (fox-room)
BR7500645U (pt)	1996-01-02	Disposição construtiva aplicada a óculos
KR970009974U (ko)	1997-03-29	도어체커플레이트
KR970007085U (ko)	1997-02-21	음악 정보 확인 방법

Legal Events

Date	Code	Title	Description
1998-01-15	8181	Inventor (new situation)	Free format text: MILLS, STUART, MACCLESFIELD, CHESHIRE, GB
1998-04-23	8180	Miscellaneous part 1	Free format text: DIE BEZEICHNUNG IST ZU AENDERN IN: (-)-(3R)-3-METHYL-4-(4-(4-(4-PYRIDYL)PIPERAZIN-1-YL)PHENOXY)BUTTERSAEURE ALS ZELLADHAESIONSINHIBITOR
2003-03-13	8139	Disposal/non-payment of the annual fee