CY2431B1 - Novel phenanthridines substituted in the 6 position. - Google Patents
Novel phenanthridines substituted in the 6 position.Info
- Publication number
- CY2431B1 CY2431B1 CY0400018A CY0400018A CY2431B1 CY 2431 B1 CY2431 B1 CY 2431B1 CY 0400018 A CY0400018 A CY 0400018A CY 0400018 A CY0400018 A CY 0400018A CY 2431 B1 CY2431 B1 CY 2431B1
- Authority
- CY
- Cyprus
- Prior art keywords
- novel
- substituted
- phenanthridines substituted
- novel phenanthridines
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/10—Aza-phenanthrenes
- C07D221/12—Phenanthridines
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19611922 | 1996-03-26 | ||
| EP96105038 | 1996-03-29 | ||
| DE1996113091 DE19613091A1 (de) | 1996-04-02 | 1996-04-02 | 6-Phenylphenanthridine |
| EP96105311 | 1996-04-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY2431B1 true CY2431B1 (en) | 2004-11-12 |
Family
ID=27438318
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY0400018A CY2431B1 (en) | 1996-03-26 | 2004-03-12 | Novel phenanthridines substituted in the 6 position. |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0889886B1 (pt) |
| JP (1) | JP4141501B2 (pt) |
| AT (1) | ATE224386T1 (pt) |
| AU (1) | AU718752B2 (pt) |
| CA (1) | CA2250569C (pt) |
| CY (1) | CY2431B1 (pt) |
| DE (1) | DE59708265D1 (pt) |
| DK (1) | DK0889886T5 (pt) |
| ES (1) | ES2184077T3 (pt) |
| PT (1) | PT889886E (pt) |
| SI (1) | SI0889886T1 (pt) |
| WO (1) | WO1997035854A1 (pt) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EE04054B1 (et) * | 1997-07-25 | 2003-06-16 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Tetrasoolderivaadid, nende kasutamine ravimite valmistamiseks ja neid sisaldav ravim |
| DK1000035T3 (da) * | 1997-07-25 | 2003-03-17 | Altana Pharma Ag | Substituerede 6-phenylphenanthridiner |
| AR015966A1 (es) * | 1997-10-17 | 2001-05-30 | Smithkline Beecham Corp | Uso de un compuesto inhibidor de pde4 para la preparacion de un medicamento util para el tratamiento de prurito |
| IT1296985B1 (it) | 1997-12-19 | 1999-08-03 | Zambon Spa | Derivati benzazinici inibitori della fosfodiesterasi 4 |
| WO2000042034A1 (en) * | 1999-01-15 | 2000-07-20 | Byk Gulden | Phenanthridine-n-oxides with pde-iv inhibiting activity |
| CZ300366B6 (cs) * | 1999-01-15 | 2009-05-06 | Nycomed Gmbh | Fenylfenanthridinová sloucenina, farmaceutický prostredek s jejím obsahem a její použití |
| ES2242594T3 (es) * | 1999-01-15 | 2005-11-16 | Altana Pharma Ag | N-oxidos de fenantridinas con una acitvidad inhidora de pde-iv. |
| WO2000042019A1 (en) * | 1999-01-15 | 2000-07-20 | Byk Gulden Lomberg Chemische Fabrik Gmbh | 6-arylphenanthridines with pde-iv inhibiting activity |
| DE60033918D1 (de) * | 1999-01-15 | 2007-04-26 | Altana Pharma Ag | Polysubstituted 6-phenylphenanthridines mit pde-iv hemmender wirkung |
| DE60043318D1 (de) | 1999-08-21 | 2010-01-14 | Nycomed Gmbh | Synergistische kombination von pumafentrine und salmeterol |
| JP2003519686A (ja) * | 2000-01-11 | 2003-06-24 | アルタナ ファルマ アクチエンゲゼルシャフト | フェナントリジン−ｎ−オキシド |
| AU2001269126A1 (en) * | 2000-07-14 | 2002-01-30 | Byk Gulden Lomberg Chemische Fabrik G.M.B.H. | Phenanthridine n-oxides |
| WO2002006238A1 (en) * | 2000-07-14 | 2002-01-24 | Altana Pharma Ag | Cycloalkyl - or cycloalkylmethyl-substituted 6-phenylphenanthridines |
| AU2001281965A1 (en) * | 2000-07-14 | 2002-01-30 | Byk Gulden Lomberg Chemische Fabrik G.M.B.H. | Novel 6-phenylphenanthridines |
| AU8393501A (en) | 2000-07-14 | 2002-01-30 | Byk Gulden Lomberg Chem Fab | Novel 6-heteroarylphenanthridines |
| US7329676B2 (en) | 2002-08-29 | 2008-02-12 | Nycomed Gmbh | 2-hydroxy-6-phenylphenanthridines as PDE-4 inhibitors |
| DE60311662T2 (de) | 2002-08-29 | 2007-10-25 | Altana Pharma Ag | 3-hydroxy-6-phenylphenanthridine als pde-4 inhibitoren |
| EP1624893A2 (en) | 2003-04-01 | 2006-02-15 | Applied Research Systems ARS Holding N.V. | Inhibitors of phosphodiesterases in infertility |
| EP1658271A1 (en) * | 2003-07-31 | 2006-05-24 | ALTANA Pharma AG | Novel 6-phenylphenanthridines |
| US20060189645A1 (en) * | 2003-07-31 | 2006-08-24 | Altana Pharma Ag | Novel 6-phenylphenantridines |
| JP4728259B2 (ja) | 2004-02-18 | 2011-07-20 | ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング | 効果的なホスホジエステラーゼ（ｐｄｅ）４インヒビターとしての新規のグアニジニル置換されたヒドロキシ−６−フェニルフェナントリジン |
| CA2557752C (en) | 2004-03-03 | 2012-10-02 | Altana Pharma Ag | Hydroxy-6-heteroaryl-phenanthridines and their use as pde4 inhibitors |
| BRPI0508361A (pt) * | 2004-03-09 | 2007-11-20 | Altana Pharma Ag | hidróxi-6-fenilfenantridinas substituìdas por isoamido |
| US20080161339A1 (en) * | 2004-03-10 | 2008-07-03 | Altana Pharma Ag | Novel Thio-Containing Hydroxy-6-Phenylphenanthridines and their Use as Pde4 Inhibitors |
| JP2007527898A (ja) * | 2004-03-10 | 2007-10-04 | アルタナ ファルマ アクチエンゲゼルシャフト | ジフルオロエトキシ置換された新規のヒドロキシ−６−フェニルフェナントリジン及びｐｄｅ４インヒビターとしてのそれらの使用 |
| US20080119505A1 (en) | 2005-02-01 | 2008-05-22 | Altana Pharma Ag | Novel 6-Pyridylphenanthridines |
| RS51345B (en) | 2005-03-02 | 2011-02-28 | Nycomed Gmbh | (2R, 4aR, 10bR) -6- (2,6-DIMETOXYPYRIDIN-3-IL) -9-ETOXY-8-METHOXY-1,2,3,4,4a, 10b-Hexahydrophenanthridin-2-OL, HCl SO |
| JP2008531654A (ja) * | 2005-03-02 | 2008-08-14 | ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング | 炎症性疾患の治療のためのＰＤＥ４インヒビターとしての６−ヘテロアリール−１，２，３，４，４ａ，１０ｂ−ヘキサヒドロフェナントリジン |
| BRPI0615102A2 (pt) * | 2005-08-30 | 2011-05-03 | Abbott Lab | composto, composições farmacêuticas como inibidores de dipeptidil peptidase-iv (dpp-iv), bem como uso |
| UY35543A (es) * | 2013-04-30 | 2014-11-28 | Bayer Cropscience Ag | N-(fenilcicloalquil)carboxamidas y n-(fenilcicloalquil)tiocarboxamidas nematicidas |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE786031A (fr) * | 1971-07-08 | 1973-01-08 | Rhone Poulenc Sa | Nouveaux derives de la phenanthridine, leur preparation et les compositions medicinales qui les contiennent |
| US4309545A (en) * | 1980-07-28 | 1982-01-05 | Pfizer Inc. | Oximino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof |
-
1997
- 1997-03-24 WO PCT/EP1997/001487 patent/WO1997035854A1/de active IP Right Grant
- 1997-03-24 SI SI9730427T patent/SI0889886T1/xx unknown
- 1997-03-24 ES ES97915422T patent/ES2184077T3/es not_active Expired - Lifetime
- 1997-03-24 EP EP97915422A patent/EP0889886B1/de not_active Expired - Lifetime
- 1997-03-24 DK DK97915422T patent/DK0889886T5/da active
- 1997-03-24 CA CA002250569A patent/CA2250569C/en not_active Expired - Fee Related
- 1997-03-24 AT AT97915422T patent/ATE224386T1/de not_active IP Right Cessation
- 1997-03-24 AU AU22910/97A patent/AU718752B2/en not_active Ceased
- 1997-03-24 PT PT97915422T patent/PT889886E/pt unknown
- 1997-03-24 DE DE59708265T patent/DE59708265D1/de not_active Expired - Lifetime
- 1997-03-24 JP JP53403097A patent/JP4141501B2/ja not_active Expired - Fee Related
-
2004
- 2004-03-12 CY CY0400018A patent/CY2431B1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK0889886T3 (da) | 2003-01-20 |
| WO1997035854A1 (de) | 1997-10-02 |
| CA2250569C (en) | 2005-05-10 |
| EP0889886A1 (de) | 1999-01-13 |
| JP2000507256A (ja) | 2000-06-13 |
| JP4141501B2 (ja) | 2008-08-27 |
| DK0889886T5 (da) | 2003-02-24 |
| ATE224386T1 (de) | 2002-10-15 |
| PT889886E (pt) | 2003-02-28 |
| EP0889886B1 (de) | 2002-09-18 |
| DE59708265D1 (de) | 2002-10-24 |
| AU2291097A (en) | 1997-10-17 |
| AU718752B2 (en) | 2000-04-20 |
| CA2250569A1 (en) | 1997-10-02 |
| ES2184077T3 (es) | 2003-04-01 |
| SI0889886T1 (en) | 2003-02-28 |
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