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CY1119454T1 - Αντισωματα εναντι cd38 για τη θεραπεια του πολλαπλου μυελωματος - Google Patents

Αντισωματα εναντι cd38 για τη θεραπεια του πολλαπλου μυελωματος

Info

Publication number
CY1119454T1
CY1119454T1 CY20171101072T CY171101072T CY1119454T1 CY 1119454 T1 CY1119454 T1 CY 1119454T1 CY 20171101072 T CY20171101072 T CY 20171101072T CY 171101072 T CY171101072 T CY 171101072T CY 1119454 T1 CY1119454 T1 CY 1119454T1
Authority
CY
Cyprus
Prior art keywords
treatment
antibodies against
multiple myeloma
human
disclosed
Prior art date
Application number
CY20171101072T
Other languages
English (en)
Inventor
Yvo Graus
Paul Parren
Jan Van De Winkel
Michel De Weers
Judith Oprins
Martine Van Vugt
Original Assignee
Genmab A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36617365&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1119454(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genmab A/S filed Critical Genmab A/S
Publication of CY1119454T1 publication Critical patent/CY1119454T1/el

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    • C—CHEMISTRY; METALLURGY
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • G—PHYSICS
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
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    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/99—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • C12Y204/99002—Monosialoganglioside sialyltransferase (2.4.99.2)
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    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
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    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/91—Transferases (2.)
    • G01N2333/91091—Glycosyltransferases (2.4)
    • G01N2333/91148—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)

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Abstract

Αποκαλύπτονται απομονωθέντα ανθρώπινα μονοκλωνικά αντισώματα, τα οποία δεσμεύονται με ανθρώπινο CD38, καθώς και σχετικές βασιζόμενες σε αντίσωμα συνθέσεις και μόρια. Αποκαλύπτονται επίσης φαρμακευτικές συνθέσεις που περιλαμβάνουν τα ανθρώπινα αντισώματα, καθώς και θεραπευτικές και διαγνωστικές μέθοδοι για χρήση των ανθρώπινων αντισωμάτων.
CY20171101072T 2005-03-23 2017-10-12 Αντισωματα εναντι cd38 για τη θεραπεια του πολλαπλου μυελωματος CY1119454T1 (el)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA200500429 2005-03-23
US66757905P 2005-04-01 2005-04-01
US69616305P 2005-07-01 2005-07-01
US72856105P 2005-10-20 2005-10-20
EP06722861.9A EP1866338B1 (en) 2005-03-23 2006-03-23 Antibodies against cd38 for treatment of multiple myeloma

Publications (1)

Publication Number Publication Date
CY1119454T1 true CY1119454T1 (el) 2018-03-07

Family

ID=36617365

Family Applications (3)

Application Number Title Priority Date Filing Date
CY20161101321T CY1118369T1 (el) 2005-03-23 2016-12-20 Αντισωματα εναντι cd38 για την θεραπεια πολλαπλου μυελωματος
CY20171101072T CY1119454T1 (el) 2005-03-23 2017-10-12 Αντισωματα εναντι cd38 για τη θεραπεια του πολλαπλου μυελωματος
CY2017044C CY2017044I2 (el) 2005-03-23 2017-12-20 Αντισωματα εναντι cd38 για τη θεραπεια του πολλαπλου μυελωματος

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CY20161101321T CY1118369T1 (el) 2005-03-23 2016-12-20 Αντισωματα εναντι cd38 για την θεραπεια πολλαπλου μυελωματος

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US (5) US7829673B2 (el)
EP (6) EP3312196B1 (el)
JP (12) JP5225069B2 (el)
KR (1) KR101433381B1 (el)
CN (4) CN107033243B (el)
AU (1) AU2006226733C9 (el)
BR (1) BRPI0608927B1 (el)
CA (1) CA2602375C (el)
CY (3) CY1118369T1 (el)
DK (1) DK2567976T3 (el)
EA (2) EA037929B1 (el)
ES (1) ES2716874T3 (el)
FR (1) FR18C1003I2 (el)
HR (2) HRP20161766T1 (el)
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PL (1) PL2567976T3 (el)
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SG (1) SG10201912554TA (el)
SI (1) SI2567976T1 (el)
WO (1) WO2006099875A1 (el)
ZA (1) ZA200709003B (el)

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CN1642983A (zh) 2002-01-25 2005-07-20 G2治疗有限公司 抗C5aR抗体及其应用
US9200061B2 (en) 2004-02-06 2015-12-01 Morpho Sys AG Generation and profiling of fully human HuCAL gold®-derived therapeutic antibodies specific for human CD3i
US8263746B2 (en) * 2004-02-06 2012-09-11 Morphosys Ag Anti-CD38 human antibodies and uses thereof
NZ586780A (en) 2005-03-23 2012-02-24 Genmab As Antibodies against CD38 for treatment of multiple myeloma
TWI428444B (zh) 2005-10-12 2014-03-01 Morphosys Ag 由全長人類ＨｕＣＡＬ ＧＯＬＤ-衍生之對人類ＣＤ３８有特異性之治療抗體之產生及鑑定
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