CY1118750T1 - Καινοφανη συντηγμενα παραγωγα πυριμιδινης για την αναστολη της δρασης της τυροσινικης κινασης - Google Patents
Καινοφανη συντηγμενα παραγωγα πυριμιδινης για την αναστολη της δρασης της τυροσινικης κινασηςInfo
- Publication number
- CY1118750T1 CY1118750T1 CY20171100349T CY171100349T CY1118750T1 CY 1118750 T1 CY1118750 T1 CY 1118750T1 CY 20171100349 T CY20171100349 T CY 20171100349T CY 171100349 T CY171100349 T CY 171100349T CY 1118750 T1 CY1118750 T1 CY 1118750T1
- Authority
- CY
- Cyprus
- Prior art keywords
- pyrimidine
- tyrosin
- producers
- suspend
- chinese
- Prior art date
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
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- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
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Abstract
Η παρούσα εφεύρεση αφορά καινοφανές συντηγμένο παράγωγο πυριμιδίνης που έχει ανασταλτική δράση για τις τυροσινικές κινάσες, καθώς και φαρμακευτική σύνθεση για την πρόληψη ή την αντιμετώπιση καρκίνων, νεοπλασιών, φλεγμονωδών νοσημάτων, αυτοάνοσων παθήσεων ή ανοσολογικώς διαμεσολαβούμενων νόσων που το περιέχει ως δραστικό συστατικό.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20100059686 | 2010-06-23 | ||
PCT/KR2011/004482 WO2011162515A2 (en) | 2010-06-23 | 2011-06-20 | Novel fused pyrimidine derivatives for inhd3ition of tyrosine kinase activity |
Publications (1)
Publication Number | Publication Date |
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CY1118750T1 true CY1118750T1 (el) | 2017-07-12 |
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