CY1117957T1 - Συμπληρωμενο omv εμβολιο εναντι μηνιγγιοκοκκου - Google Patents
Συμπληρωμενο omv εμβολιο εναντι μηνιγγιοκοκκουInfo
- Publication number
- CY1117957T1 CY1117957T1 CY20161100845T CY161100845T CY1117957T1 CY 1117957 T1 CY1117957 T1 CY 1117957T1 CY 20161100845 T CY20161100845 T CY 20161100845T CY 161100845 T CY161100845 T CY 161100845T CY 1117957 T1 CY1117957 T1 CY 1117957T1
- Authority
- CY
- Cyprus
- Prior art keywords
- omv
- miningokok
- vacancy
- full
- component
- Prior art date
Links
- 230000002163 immunogen Effects 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 241000588653 Neisseria Species 0.000 abstract 1
- 241000588677 Neisseria meningitidis serogroup B Species 0.000 abstract 1
- 101710194807 Protective antigen Proteins 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 244000052769 pathogen Species 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6068—Other bacterial proteins, e.g. OMP
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Biotechnology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Abstract
Σύνθεση περιλαμβάνουσα (a) φλύκταινες εξωτερικής μεμβράνης Neisseria meningitidis οροομάδας Β (OMVs) και (b) ανοσογονικό συστατικό που επιλέγεται από άλλες πρωτεΐνες Neisseria, ή ανοσογονικά θραύσματα αυτών. Το συστατικό (b) κατά προτίμηση περιλαμβάνει πρωτεΐνη από διαφορετικό NmB στέλεχος από αυτό από το οποίο λαμβάνεται το OMV συστατικό (a). Τα OMVs κατά προτίμηση λαμβάνονται με εκχύλιση δεοξυχολικού. Προαιρετικώς, η σύνθεση μπορεί επίσης να περιλαμβάνει προστατευτικό αντιγόνο έναντι άλλων παθογόνων.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0001067A GB0001067D0 (en) | 2000-01-17 | 2000-01-17 | Supplemented norwegian vaccine |
GBGB0005699.4A GB0005699D0 (en) | 2000-03-09 | 2000-03-09 | Supplemented OMV vaccines |
EP07013453.1A EP1897555B1 (en) | 2000-01-17 | 2001-01-17 | Supplemented OMV vaccine against meningococcus |
EP01942562A EP1248647B1 (en) | 2000-01-17 | 2001-01-17 | Outer membrane vesicle (omv) vaccine comprising n. meningitidis serogroup b outer membrane proteins |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1117957T1 true CY1117957T1 (el) | 2017-05-17 |
Family
ID=26243421
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20101101003T CY1111056T1 (el) | 2000-01-17 | 2010-11-04 | Εμβολιο κυστιδιου εξωτερικης μεμβρανης (omv) που περιλαμβανει πρωτεϊνες εξωτερικης μεμβρανης απο ν. meningitidis οροομαδας β |
CY20141100751T CY1115842T1 (el) | 2000-01-17 | 2014-09-17 | Συμπληρωμενο ομv εμβολιο κατα μηνιγγιtiδοκοκκου |
CY20161100845T CY1117957T1 (el) | 2000-01-17 | 2016-08-29 | Συμπληρωμενο omv εμβολιο εναντι μηνιγγιοκοκκου |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20101101003T CY1111056T1 (el) | 2000-01-17 | 2010-11-04 | Εμβολιο κυστιδιου εξωτερικης μεμβρανης (omv) που περιλαμβανει πρωτεϊνες εξωτερικης μεμβρανης απο ν. meningitidis οροομαδας β |
CY20141100751T CY1115842T1 (el) | 2000-01-17 | 2014-09-17 | Συμπληρωμενο ομv εμβολιο κατα μηνιγγιtiδοκοκκου |
Country Status (17)
Country | Link |
---|---|
US (4) | US8273360B2 (el) |
EP (6) | EP2281570A3 (el) |
JP (6) | JP2003520248A (el) |
CN (2) | CN102172398A (el) |
AT (1) | ATE476988T1 (el) |
AU (2) | AU784518B2 (el) |
BR (2) | BR0107679A (el) |
CA (2) | CA2871789C (el) |
CY (3) | CY1111056T1 (el) |
DE (1) | DE60142772D1 (el) |
DK (3) | DK1897555T3 (el) |
ES (2) | ES2588917T3 (el) |
MX (1) | MXPA02006962A (el) |
NZ (1) | NZ520466A (el) |
PT (3) | PT1248647E (el) |
RU (1) | RU2279889C2 (el) |
WO (1) | WO2001052885A1 (el) |
Families Citing this family (118)
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AU1463097A (en) | 1996-01-04 | 1997-08-01 | Rican Limited | Helicobacter pylori bacterioferritin |
EP1860192A1 (en) | 1996-09-17 | 2007-11-28 | Novartis Vaccines and Diagnostics, Inc. | Compositions and methods for treating intracellular diseases |
CA2650642A1 (en) | 1998-05-01 | 1999-11-11 | Chiron Corporation | Neisseria meningitidis antigens and compositions |
US20070026021A1 (en) * | 1998-05-01 | 2007-02-01 | Chiron S.R.I. | Neisseria meningitidis antigens and compositions |
GB9823978D0 (en) * | 1998-11-02 | 1998-12-30 | Microbiological Res Authority | Multicomponent meningococcal vaccine |
US10967045B2 (en) * | 1998-11-02 | 2021-04-06 | Secretary of State for Health and Social Care | Multicomponent meningococcal vaccine |
WO2000050075A2 (en) * | 1999-02-26 | 2000-08-31 | Chiron S.P.A. | Enhancement of bactericidal activity of neisseria antigens with oligonucleotides containing cg motifs |
AU4309600A (en) | 1999-04-30 | 2000-11-17 | Chiron S.R.L. | Conserved neisserial antigens |
BR0010721A (pt) | 1999-05-19 | 2002-06-11 | Chiron Spa | Composições de neisserias combinadas |
CA2389321A1 (en) | 1999-10-29 | 2001-05-03 | Chiron S.P.A. | Neisserial antigenic peptides |
GB9928196D0 (en) | 1999-11-29 | 2000-01-26 | Chiron Spa | Combinations of B, C and other antigens |
BR0107679A (pt) * | 2000-01-17 | 2004-07-06 | Chiron Spa | Vacina de vesìcula de membrana externa (omv) compreendendo proteìnas de membrana externa do grupo sérico b de neisseria meningitidis |
RU2304617C2 (ru) | 2000-02-28 | 2007-08-20 | Новартис Вэксинс Энд Диагностикс С.Р.Л. | Гибридная экспрессия белков neisseria |
EP1322328B1 (en) | 2000-07-27 | 2014-08-20 | Children's Hospital & Research Center at Oakland | Vaccines for broad spectrum protection against diseases caused by neisseria meningitidis |
GB0103170D0 (en) * | 2001-02-08 | 2001-03-28 | Smithkline Beecham Biolog | Vaccine composition |
MX357775B (es) | 2000-10-27 | 2018-07-20 | J Craig Venter Inst Inc | Acidos nucleicos y proteinas de los grupos a y b de estreptococos. |
GB0107658D0 (en) | 2001-03-27 | 2001-05-16 | Chiron Spa | Streptococcus pneumoniae |
GB0107661D0 (en) | 2001-03-27 | 2001-05-16 | Chiron Spa | Staphylococcus aureus |
GB0115176D0 (en) | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
GB0118249D0 (en) | 2001-07-26 | 2001-09-19 | Chiron Spa | Histidine vaccines |
CA2452836C (en) | 2001-07-27 | 2012-11-27 | Chiron Srl | Meningococcus adhesins nada, app and orf 40 |
GB0121591D0 (en) | 2001-09-06 | 2001-10-24 | Chiron Spa | Hybrid and tandem expression of neisserial proteins |
MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
JP4413617B2 (ja) | 2001-12-12 | 2010-02-10 | カイロン ソチエタ ア レスポンサビリタ リミタータ | Chlamydiatrachomatisに対する免疫化 |
GB0130123D0 (en) | 2001-12-17 | 2002-02-06 | Microbiological Res Agency | Outer membrane vesicle vaccine and its preparation |
AU2003269864A1 (en) * | 2002-08-02 | 2004-02-25 | Glaxosmithkline Biologicals Sa | Vaccine composition comprising lipooligosaccharide with reduced phase variability |
RU2359696C2 (ru) * | 2002-08-02 | 2009-06-27 | ГлаксоСмитКлайн Байолоджикалз с.а. | Вакцинная композиция, содержащая трансферрин-связывающий белок и hsf из грамотрицательных бактерий |
GB0220194D0 (en) | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
SI2353608T1 (sl) | 2002-10-11 | 2020-12-31 | Glaxosmithkline Biologicals Sa | Polipeptidna cepiva za široko zaščito proti hipervirulentnim meningokoknim linijam |
CA2503871C (en) | 2002-11-01 | 2012-12-11 | Glaxosmithkline Biologicals S.A. | An immunogenic composition for generating an immune response against polio virus |
CA2506318C (en) | 2002-11-15 | 2011-07-12 | Chiron Srl | Unexpected surface proteins in neisseria meningitidis |
GB0227346D0 (en) * | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
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CN1798548B (zh) | 2003-06-02 | 2010-05-05 | 诺华疫苗和诊断公司 | 基于含吸附类毒素和含多糖抗原微粒体的免疫原性组合物 |
GB0323103D0 (en) | 2003-10-02 | 2003-11-05 | Chiron Srl | De-acetylated saccharides |
GB0406013D0 (en) | 2004-03-17 | 2004-04-21 | Chiron Srl | Analysis of saccharide vaccines without interference |
GB0408977D0 (en) | 2004-04-22 | 2004-05-26 | Chiron Srl | Immunising against meningococcal serogroup Y using proteins |
EP1740217B1 (en) * | 2004-04-30 | 2011-06-15 | Novartis Vaccines and Diagnostics S.r.l. | Meningococcal conjugate vaccination |
GB0411387D0 (en) | 2004-05-21 | 2004-06-23 | Chiron Srl | Analysis of saccharide length |
GB0413868D0 (en) | 2004-06-21 | 2004-07-21 | Chiron Srl | Dimensional anlaysis of saccharide conjugates |
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EP1765313A2 (en) | 2004-06-24 | 2007-03-28 | Novartis Vaccines and Diagnostics, Inc. | Compounds for immunopotentiation |
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GB0700562D0 (en) | 2007-01-11 | 2007-02-21 | Novartis Vaccines & Diagnostic | Modified Saccharides |
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BRPI0821240B8 (pt) | 2007-12-21 | 2022-10-04 | Novartis Ag | formas mutantes de estreptolisina o |
CA2716212A1 (en) * | 2008-02-21 | 2009-08-27 | Novartis Ag | Meningococcal fhbp polypeptides |
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