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CY1117957T1 - Συμπληρωμενο omv εμβολιο εναντι μηνιγγιοκοκκου - Google Patents

Συμπληρωμενο omv εμβολιο εναντι μηνιγγιοκοκκου

Info

Publication number
CY1117957T1
CY1117957T1 CY20161100845T CY161100845T CY1117957T1 CY 1117957 T1 CY1117957 T1 CY 1117957T1 CY 20161100845 T CY20161100845 T CY 20161100845T CY 161100845 T CY161100845 T CY 161100845T CY 1117957 T1 CY1117957 T1 CY 1117957T1
Authority
CY
Cyprus
Prior art keywords
omv
miningokok
vacancy
full
component
Prior art date
Application number
CY20161100845T
Other languages
English (en)
Inventor
Mariagrazia Pizza
Rino Rappuoli
Marzia Giuliani
Original Assignee
Glaxosmithkline Biologicals Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0001067A external-priority patent/GB0001067D0/en
Priority claimed from GBGB0005699.4A external-priority patent/GB0005699D0/en
Application filed by Glaxosmithkline Biologicals Sa filed Critical Glaxosmithkline Biologicals Sa
Publication of CY1117957T1 publication Critical patent/CY1117957T1/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/095Neisseria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6068Other bacterial proteins, e.g. OMP
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Biotechnology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)

Abstract

Σύνθεση περιλαμβάνουσα (a) φλύκταινες εξωτερικής μεμβράνης Neisseria meningitidis οροομάδας Β (OMVs) και (b) ανοσογονικό συστατικό που επιλέγεται από άλλες πρωτεΐνες Neisseria, ή ανοσογονικά θραύσματα αυτών. Το συστατικό (b) κατά προτίμηση περιλαμβάνει πρωτεΐνη από διαφορετικό NmB στέλεχος από αυτό από το οποίο λαμβάνεται το OMV συστατικό (a). Τα OMVs κατά προτίμηση λαμβάνονται με εκχύλιση δεοξυχολικού. Προαιρετικώς, η σύνθεση μπορεί επίσης να περιλαμβάνει προστατευτικό αντιγόνο έναντι άλλων παθογόνων.
CY20161100845T 2000-01-17 2016-08-29 Συμπληρωμενο omv εμβολιο εναντι μηνιγγιοκοκκου CY1117957T1 (el)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0001067A GB0001067D0 (en) 2000-01-17 2000-01-17 Supplemented norwegian vaccine
GBGB0005699.4A GB0005699D0 (en) 2000-03-09 2000-03-09 Supplemented OMV vaccines
EP07013453.1A EP1897555B1 (en) 2000-01-17 2001-01-17 Supplemented OMV vaccine against meningococcus
EP01942562A EP1248647B1 (en) 2000-01-17 2001-01-17 Outer membrane vesicle (omv) vaccine comprising n. meningitidis serogroup b outer membrane proteins

Publications (1)

Publication Number Publication Date
CY1117957T1 true CY1117957T1 (el) 2017-05-17

Family

ID=26243421

Family Applications (3)

Application Number Title Priority Date Filing Date
CY20101101003T CY1111056T1 (el) 2000-01-17 2010-11-04 Εμβολιο κυστιδιου εξωτερικης μεμβρανης (omv) που περιλαμβανει πρωτεϊνες εξωτερικης μεμβρανης απο ν. meningitidis οροομαδας β
CY20141100751T CY1115842T1 (el) 2000-01-17 2014-09-17 Συμπληρωμενο ομv εμβολιο κατα μηνιγγιtiδοκοκκου
CY20161100845T CY1117957T1 (el) 2000-01-17 2016-08-29 Συμπληρωμενο omv εμβολιο εναντι μηνιγγιοκοκκου

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CY20101101003T CY1111056T1 (el) 2000-01-17 2010-11-04 Εμβολιο κυστιδιου εξωτερικης μεμβρανης (omv) που περιλαμβανει πρωτεϊνες εξωτερικης μεμβρανης απο ν. meningitidis οροομαδας β
CY20141100751T CY1115842T1 (el) 2000-01-17 2014-09-17 Συμπληρωμενο ομv εμβολιο κατα μηνιγγιtiδοκοκκου

Country Status (17)

Country Link
US (4) US8273360B2 (el)
EP (6) EP2281570A3 (el)
JP (6) JP2003520248A (el)
CN (2) CN102172398A (el)
AT (1) ATE476988T1 (el)
AU (2) AU784518B2 (el)
BR (2) BR0107679A (el)
CA (2) CA2871789C (el)
CY (3) CY1111056T1 (el)
DE (1) DE60142772D1 (el)
DK (3) DK1897555T3 (el)
ES (2) ES2588917T3 (el)
MX (1) MXPA02006962A (el)
NZ (1) NZ520466A (el)
PT (3) PT1248647E (el)
RU (1) RU2279889C2 (el)
WO (1) WO2001052885A1 (el)

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EP1248647A1 (en) 2002-10-16
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DE60142772D1 (de) 2010-09-23
AU2875401A (en) 2001-07-31
RU2279889C2 (ru) 2006-07-20
AU784518B2 (en) 2006-04-27
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