US4879236A
(en)
*
|
1984-05-16 |
1989-11-07 |
The Texas A&M University System |
Method for producing a recombinant baculovirus expression vector
|
JPS619288A
(ja)
*
|
1984-06-21 |
1986-01-16 |
Dai Ichi Seiyaku Co Ltd |
ペプチド類の製法
|
IL80529A0
(en)
*
|
1985-11-14 |
1987-02-27 |
Daiichi Seiyaku Co |
Method of producing peptides
|
AU599348B2
(en)
*
|
1985-12-18 |
1990-07-19 |
Microgenesys, Inc. |
Method for producing selected polypeptides in virally infected insect cells and polypeptides isolated therefrom
|
IL83003A
(en)
|
1986-07-01 |
1995-07-31 |
Genetics Inst |
Factors that soak bone formation
|
GR871029B
(en)
|
1986-07-14 |
1987-11-02 |
Genetics Inst |
Novel osteoinductive factors
|
EP0260090A3
(en)
*
|
1986-09-08 |
1988-07-27 |
David H.L. Bishop |
Expression of hepatitis b viral antigens from recombinant baculovirus vectors
|
US5071748A
(en)
*
|
1986-09-09 |
1991-12-10 |
Genetics Institute, Inc. |
Mixed baculovirus compositions and uses thereof
|
ES2008204A6
(es)
*
|
1986-09-09 |
1989-07-16 |
Genetics Inst |
Metodos para producir cuerpos de inclusion polihedrica de composicion mezclada (pib),para coinfectar insectos huespedes y para producir proteinas heterologas en insectos.
|
US5041379A
(en)
*
|
1987-03-16 |
1991-08-20 |
American Biogenetic Science, Inc. |
Heliothis expression systems
|
US5024947A
(en)
*
|
1987-07-24 |
1991-06-18 |
Cetus Corporation |
Serum free media for the growth on insect cells and expression of products thereby
|
US5578468A
(en)
*
|
1987-08-10 |
1996-11-26 |
Duke University |
Site-specific RNA cleavage
|
US5443964A
(en)
*
|
1987-08-10 |
1995-08-22 |
Duke University |
Poxvirus insertion/expression vector
|
GB8810808D0
(en)
*
|
1988-05-06 |
1988-06-08 |
Wellcome Found |
Vectors
|
JP2511494B2
(ja)
*
|
1988-05-12 |
1996-06-26 |
善治 松浦 |
日本脳炎ウイルス表面抗原蛋白質の製造法
|
JPH0221955A
(ja)
*
|
1988-07-07 |
1990-01-24 |
Nippon Steel Corp |
流体噴射ノズル
|
SE8802939D0
(sv)
*
|
1988-08-19 |
1988-08-19 |
Kabigen Ab |
A method for the production and isolation of a fusion protein in eukaryotic cells
|
US5811523A
(en)
|
1988-11-10 |
1998-09-22 |
Trinchieri; Giorgio |
Antibodies to natural killer stimulatory factor
|
AU4647889A
(en)
*
|
1988-11-18 |
1990-06-12 |
Cetus Corporation |
Insect signal peptide mediated secretion of recombinant proteins
|
US5244805A
(en)
*
|
1989-05-17 |
1993-09-14 |
University Of Georgia Research Foundation, Inc. |
Baculovirus expression vectors
|
AU674500B2
(en)
|
1991-11-04 |
1997-01-02 |
Genetics Institute, Llc |
Recombinant bone morphogenetic protein heterodimers, compositions and methods of use
|
DK0698094T3
(da)
|
1993-05-12 |
2004-05-03 |
Inst Genetics Llc |
BMP-11-sammensætninger
|
US6027919A
(en)
|
1993-12-07 |
2000-02-22 |
Genetics Institute, Inc. |
BMP-12 and BMP-13 proteins and DNA encoding them
|
CA2179394A1
(en)
*
|
1993-12-23 |
1995-06-29 |
Kostas Iatrou |
Methods of expressing proteins in insect cells and methods of killing insects
|
US5629167A
(en)
|
1994-04-19 |
1997-05-13 |
Biocine S.P.A. |
Detection of antibodies against Chlamydia trachomatis pgp3 antigen in patient sera by enzyme-linked immunosorbent assay
|
US6544523B1
(en)
|
1996-11-13 |
2003-04-08 |
Chiron Corporation |
Mutant forms of Fas ligand and uses thereof
|
US6165748A
(en)
|
1997-07-11 |
2000-12-26 |
Genetics Institute, Inc. |
Frazzled nucleotide sequences and expression products
|
ATE421527T1
(de)
|
1997-08-27 |
2009-02-15 |
Novartis Vaccines & Diagnostic |
Molekular-mimetika von meningokokkus b epitopen
|
CN1263854C
(zh)
|
1997-11-06 |
2006-07-12 |
启龙股份公司 |
奈瑟球菌抗原
|
DE69941567D1
(de)
|
1998-01-14 |
2009-12-03 |
Novartis Vaccines & Diagnostic |
Antigene aus neisseria meningitidis
|
GB9808932D0
(en)
|
1998-04-27 |
1998-06-24 |
Chiron Spa |
Polyepitope carrier protein
|
EP2261340B1
(en)
|
1998-05-01 |
2017-03-08 |
GlaxoSmithKline Biologicals SA |
Neisseria meningitidis antigens and compositions
|
EP1953229A3
(en)
|
1998-10-15 |
2008-12-24 |
Novartis Vaccines and Diagnostics, Inc. |
Metastatic breast and colon cancer regulated genes
|
WO2001027150A2
(en)
|
1999-10-14 |
2001-04-19 |
Clontech Laboratories Inc. |
Anthozoa derived chromo/fluoroproteins and methods for using the same
|
DK1141331T3
(da)
|
1998-12-16 |
2009-01-05 |
Novartis Vaccines & Diagnostic |
Human cyclinafhængig kinase (hPNQALRE)
|
NZ530640A
(en)
|
1999-04-30 |
2006-06-30 |
Chiron S |
Conserved neisserial antigens
|
GB9911683D0
(en)
|
1999-05-19 |
1999-07-21 |
Chiron Spa |
Antigenic peptides
|
GB9916529D0
(en)
|
1999-07-14 |
1999-09-15 |
Chiron Spa |
Antigenic peptides
|
CA2863668A1
(en)
|
1999-10-29 |
2001-05-03 |
Novartis Vaccines And Diagnostics S.R.L. |
Neisserial antigenic peptides
|
ES2311016T3
(es)
|
2000-01-10 |
2009-02-01 |
Novartis Vaccines And Diagnostics, Inc. |
Genes expresados diferencialmente en cancer de mama.
|
CN1416352B
(zh)
|
2000-01-17 |
2011-05-25 |
启龙股份公司 |
含有脑膜炎奈瑟球菌b血清群外膜蛋白质的外膜囊(omv)疫苗
|
US6689599B1
(en)
|
2000-10-20 |
2004-02-10 |
Genetics Institute, Llc |
Aggrecanase molecules
|
EP2277896A1
(en)
|
2000-10-27 |
2011-01-26 |
Novartis Vaccines and Diagnostics S.r.l. |
Nucleic acids and proteins from streptococcus groups A & B
|
TW200526779A
(en)
|
2001-02-08 |
2005-08-16 |
Wyeth Corp |
Modified and stabilized GDF propeptides and uses thereof
|
GB0107658D0
(en)
|
2001-03-27 |
2001-05-16 |
Chiron Spa |
Streptococcus pneumoniae
|
GB0107661D0
(en)
|
2001-03-27 |
2001-05-16 |
Chiron Spa |
Staphylococcus aureus
|
AU2002305151A1
(en)
|
2001-04-06 |
2002-10-21 |
Georgetown University |
Gene scc-112 and diagnostic and therapeutic uses thereof
|
AU2002258728A1
(en)
|
2001-04-06 |
2002-10-21 |
Georgetown University |
Gene brcc-3 and diagnostic and therapeutic uses thereof
|
WO2002081639A2
(en)
|
2001-04-06 |
2002-10-17 |
Georgetown University |
Gene brcc2 and diagnostic and therapeutic uses thereof
|
US7125701B2
(en)
|
2001-07-27 |
2006-10-24 |
Wyeth |
Aggrecanase molecules
|
EP2335724A1
(en)
|
2001-12-12 |
2011-06-22 |
Novartis Vaccines and Diagnostics S.r.l. |
Immunisation against chlamydia trachomatis
|
EP1456223B1
(en)
|
2001-12-19 |
2009-08-12 |
The University Of Chicago |
Rapidly maturing fluorescent proteins and methods for using the same
|
PL371525A1
(en)
|
2002-01-31 |
2005-06-27 |
Wyeth |
Aggrecanase molecules
|
EP1472364A4
(en)
|
2002-02-05 |
2005-12-28 |
Wyeth Corp |
TRUNK AGGRECANASE MOLECULES
|
US7244565B2
(en)
|
2002-04-10 |
2007-07-17 |
Georgetown University |
Gene shinc-3 and diagnostic and therapeutic uses thereof
|
US7138512B2
(en)
|
2002-04-10 |
2006-11-21 |
Georgetown University |
Gene SHINC-2 and diagnostic and therapeutic uses thereof
|
AU2003239865A1
(en)
|
2002-05-24 |
2003-12-12 |
Restoragen Inc. |
Method for universal enzymatic production of bioactive peptides
|
WO2003099854A2
(en)
|
2002-05-24 |
2003-12-04 |
Nps Allelix Corp. |
Method for enzymatic production of glp-2(1-33) and glp-2-(1-34) peptides
|
EP1562982B1
(en)
|
2002-11-15 |
2010-05-05 |
Novartis Vaccines and Diagnostics S.r.l. |
Unexpected surface proteins in neisseria meningitidis
|
GB0308198D0
(en)
|
2003-04-09 |
2003-05-14 |
Chiron Srl |
ADP-ribosylating bacterial toxin
|
CN101897974B
(zh)
|
2003-09-12 |
2013-09-25 |
惠氏公司 |
用于递送成骨蛋白的注射型磷酸钙固体小棒剂和糊剂
|
WO2005067368A2
(en)
|
2003-11-21 |
2005-07-28 |
Nps Allelix Corp. |
Production of glucagon like peptide 2 and analogs
|
CA2553035A1
(en)
|
2004-02-02 |
2005-08-18 |
Ambrx, Inc. |
Modified human growth hormone polypeptides and their uses
|
JP4792390B2
(ja)
|
2004-03-29 |
2011-10-12 |
株式会社ガルファーマ |
新規ガレクチン9改変体タンパク質及びその用途
|
WO2005100387A1
(en)
|
2004-04-07 |
2005-10-27 |
The University Of Chicago |
Monomeric red fluorescent proteins
|
EP1771205B1
(en)
|
2004-06-18 |
2016-10-26 |
Ambrx, Inc. |
Novel antigen-binding polypeptides and their uses
|
MX2007007590A
(es)
|
2004-12-22 |
2007-12-10 |
Ambrx Inc |
Composiciones que contienen, metodos que involucran y usos de aminoacidos no naturales y polipeptidos.
|
SG160437A1
(en)
|
2004-12-22 |
2010-04-29 |
Ambrx Inc |
Modified human growth hormone
|
DK1865940T3
(da)
|
2005-03-21 |
2013-03-04 |
Virobay Inc |
Alfaketoamidforbindelser som cysteinproteasehæmmere
|
WO2006124667A2
(en)
|
2005-05-12 |
2006-11-23 |
Zymogenetics, Inc. |
Compositions and methods for modulating immune responses
|
WO2007053732A2
(en)
|
2005-11-01 |
2007-05-10 |
Mayo Foundation For Medical Education And Research |
Promoter polymorphisms of the blys gene and use in diagnostic methods
|
CA2626522A1
(en)
|
2005-11-16 |
2007-05-24 |
Ambrx, Inc. |
Methods and compositions comprising non-natural amino acids
|
PT2054431E
(pt)
|
2006-06-09 |
2011-11-03 |
Novartis Ag |
Confórmeros de adesinas bacterianas
|
DK2615108T3
(da)
|
2006-09-08 |
2017-01-30 |
Ambrx Inc |
Modificeret humant plasmapolypeptid eller fc scaffolds og deres anvendelser
|
US7985783B2
(en)
|
2006-09-21 |
2011-07-26 |
The Regents Of The University Of California |
Aldehyde tags, uses thereof in site-specific protein modification
|
CA2682147C
(en)
|
2007-03-30 |
2017-08-08 |
Ambrx, Inc. |
Modified fgf-21 polypeptides and their uses
|
ES2908934T3
(es)
|
2007-10-04 |
2022-05-04 |
Zymogenetics Inc |
ZB7H6 miembro de la familia B7 y composiciones y métodos relacionados
|
WO2009059305A2
(en)
|
2007-11-01 |
2009-05-07 |
The University Of Chicago |
Red fluorescent proteins with enhanced bacterial expression, increased brightness and reduced aggregation
|
DK2217265T3
(da)
|
2007-11-20 |
2017-07-03 |
Ambrx Inc |
Modificerede insulinpolypeptider og anvendelse deraf
|
US8003325B2
(en)
|
2007-11-30 |
2011-08-23 |
Mayo Foundation For Medical Education And Research |
Polymorphisms of the BLyS gene and use in diagnostic methods
|
MX2010008632A
(es)
|
2008-02-08 |
2010-08-30 |
Ambrx Inc |
Leptina-polipeptidos modificados y sus usos.
|
EA019968B1
(ru)
|
2008-07-23 |
2014-07-30 |
Амбркс, Инк. |
Модифицированные бычьи полипептиды g-csf и их применение
|
ES2660000T3
(es)
|
2008-09-26 |
2018-03-20 |
Ambrx, Inc. |
Vacunas y microorganismos dependientes de la replicación de aminoácidos no naturales
|
CA2737026C
(en)
|
2008-09-26 |
2019-12-24 |
Ambrx, Inc. |
Modified animal erythropoietin polypeptides and their uses
|
EP2292781A1
(en)
|
2009-08-17 |
2011-03-09 |
Genethon |
Baculovirus-based production of biopharmaceuticals free of contaminating baculoviral virions
|
EP2333074A1
(en)
|
2009-12-14 |
2011-06-15 |
Robert Steinfeld |
Substances and methods for the treatment of lysosmal storage diseases
|
PE20121799A1
(es)
|
2009-12-21 |
2013-01-02 |
Ambrx Inc |
Polipeptidos de somatotropina porcina modificados y sus usos
|
US20120283171A1
(en)
|
2009-12-21 |
2012-11-08 |
Ambrx, Inc. |
Modified bovine somatotropin polypeptides and their uses
|
SI3572091T1
(sl)
|
2010-08-17 |
2024-07-31 |
Ambrx, Inc., |
Modificirani polipeptidi relaksina in njihova uporaba
|
US9567386B2
(en)
|
2010-08-17 |
2017-02-14 |
Ambrx, Inc. |
Therapeutic uses of modified relaxin polypeptides
|
AR083006A1
(es)
|
2010-09-23 |
2013-01-23 |
Lilly Co Eli |
Formulaciones para el factor estimulante de colonias de granulocitos (g-csf) bovino y variantes de las mismas
|
IN2014CN00688A
(da)
|
2011-07-27 |
2015-04-03 |
Genethon |
|
CA3178384A1
(en)
|
2013-09-12 |
2015-03-19 |
Biomarin Pharmaceutical Inc. |
Adeno-associated virus factor viii vectors
|
BR112017008157A2
(pt)
|
2014-10-24 |
2017-12-19 |
Bristol Myers Squibb Co |
polipeptídeos de fgf-21 modificados e usos dos mesmos
|
IL297353A
(en)
|
2015-09-24 |
2022-12-01 |
Biomarin Pharm Inc |
Adeno-associated virus factor 8 vectors, associated virus particles, and medicinal formulations comprising the same
|
AU2016354561B2
(en)
|
2015-11-12 |
2021-12-02 |
Research Institute At Nationwide Children's Hospital |
Methods of treating muscular dystrophy
|
AU2017301600B2
(en)
|
2016-07-26 |
2022-08-04 |
Biomarin Pharmaceutical Inc. |
Novel adeno-associated virus capsid proteins
|
AU2018219283B2
(en)
|
2017-02-08 |
2022-05-19 |
Bristol-Myers Squibb Company |
Modified relaxin polypeptides comprising a pharmacokinetic enhancer and uses thereof
|
EP3688014A4
(en)
|
2017-09-29 |
2020-09-16 |
Massachusetts Eye and Ear Infirmary |
PRODUCTION OF ADENO-ASSOCIATED VIRUSES IN INSECT CELLS
|
MX2020011937A
(es)
|
2018-05-09 |
2021-01-29 |
Biomarin Pharm Inc |
Metodos de tratamiento de fenilcetonuria.
|
TW202005978A
(zh)
|
2018-05-14 |
2020-02-01 |
美商拜奧馬林製藥公司 |
新穎肝靶向腺相關病毒載體
|
TW202016298A
(zh)
|
2018-05-14 |
2020-05-01 |
美商拜奧馬林製藥公司 |
Aav 載體於幼年受試者中之穩定表現
|
WO2020232044A1
(en)
|
2019-05-14 |
2020-11-19 |
Biomarin Pharmaceutical Inc. |
Methods of redosing gene therapy vectors
|
US20220308022A1
(en)
|
2019-09-27 |
2022-09-29 |
Biomarin Pharmaceutical Inc. |
Characterization of gene therapy viral particles using size exclusion chromatography and multi-angle light scattering technologies
|
AU2020384294A1
(en)
|
2019-11-14 |
2022-06-02 |
Biomarin Pharmaceutical Inc. |
Treatment of hereditary angioedema with liver-specific gene therapy vectors
|
US20230075854A1
(en)
|
2020-02-10 |
2023-03-09 |
Biomarin Pharmaceutical Inc. |
Virus-free cell cultures
|
WO2021183895A1
(en)
|
2020-03-13 |
2021-09-16 |
Biomarin Pharmaceutical Inc. |
Treatment of fabry disease with aav gene therapy vectors
|
AR122409A1
(es)
|
2020-04-03 |
2022-09-07 |
Biomarin Pharm Inc |
Tratamiento de la fenilcetonuria con aav y formulaciones terapéuticas
|
WO2021236908A2
(en)
|
2020-05-20 |
2021-11-25 |
Biomarin Pharmaceutical Inc. |
Use of regulatory proteins for the production of adeno-associated virus
|
US20230407328A1
(en)
|
2020-11-02 |
2023-12-21 |
Biomarin Pharmaceutical Inc. |
Process for enriching adeno-associated virus
|
EP4408481A2
(en)
|
2021-10-01 |
2024-08-07 |
BioMarin Pharmaceutical Inc. |
Treatment of hereditary angioedema with aav gene therapy vectors and therapeutic formulations
|
WO2024064863A2
(en)
|
2022-09-22 |
2024-03-28 |
Biomarin Pharmaceutical Inc. |
Treatment of arrhythmogenic cardiomyopathy with aav gene therapy vectors
|
WO2024064856A1
(en)
|
2022-09-22 |
2024-03-28 |
Biomarin Pharmaceutical Inc. |
Treatment of cardiomyopathy with aav gene therapy vectors
|
WO2024151568A1
(en)
|
2023-01-09 |
2024-07-18 |
Biomarin Pharmaceutical Inc. |
Epigenetic modifiers improve aav gene therapy durability
|
WO2024238591A2
(en)
|
2023-05-15 |
2024-11-21 |
Biomarin Pharmaceutical Inc. |
Methods of treating anti-aav seropositive hemophilia patients
|