MX2023009728A - Vacuna recombinante meningococica b. - Google Patents
Vacuna recombinante meningococica b.Info
- Publication number
- MX2023009728A MX2023009728A MX2023009728A MX2023009728A MX2023009728A MX 2023009728 A MX2023009728 A MX 2023009728A MX 2023009728 A MX2023009728 A MX 2023009728A MX 2023009728 A MX2023009728 A MX 2023009728A MX 2023009728 A MX2023009728 A MX 2023009728A
- Authority
- MX
- Mexico
- Prior art keywords
- protein
- meningococcal
- fhbp
- antigens
- present disclosure
- Prior art date
Links
- 108010008038 Synthetic Vaccines Proteins 0.000 title 1
- 229940124551 recombinant vaccine Drugs 0.000 title 1
- 101710186862 Factor H binding protein Proteins 0.000 abstract 3
- 239000000427 antigen Substances 0.000 abstract 3
- 102000036639 antigens Human genes 0.000 abstract 3
- 108091007433 antigens Proteins 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 230000002163 immunogen Effects 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 241000588653 Neisseria Species 0.000 abstract 1
- 241000588677 Neisseria meningitidis serogroup B Species 0.000 abstract 1
- 101710171321 Neuraminyllactose-binding hemagglutinin Proteins 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/36—Neisseria
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
La presente descripción se refiere a una composición inmunógena que comprende una combinación de antígenos meningocócicos que comprende al menos una proteína de unión al factor H proteína A (fHBP), al menos una proteína fHBP B, al menos una proteína adhesina A de Neisseria (NadA), y al menos una vesícula de membrana externa extraída con detergente (dOMV). Los antígenos meningocócicos pueden ser de Neisseria meningitidis del serogrupo B. La combinación de antígenos proporcionaba una amplia cobertura de cepas bacterianas. Además, la presente descripción se refiere al uso de la composición inmunógena en métodos para producir una respuesta inmunitaria.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP21305211 | 2021-02-19 | ||
US202163172885P | 2021-04-09 | 2021-04-09 | |
PCT/US2022/016894 WO2022178196A1 (en) | 2021-02-19 | 2022-02-18 | Meningococcal b recombinant vaccine |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2023009728A true MX2023009728A (es) | 2023-08-30 |
Family
ID=80595537
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2023009728A MX2023009728A (es) | 2021-02-19 | 2022-02-18 | Vacuna recombinante meningococica b. |
Country Status (11)
Country | Link |
---|---|
US (2) | US12053516B2 (es) |
EP (1) | EP4294432A1 (es) |
JP (1) | JP2024507828A (es) |
KR (1) | KR20230147075A (es) |
AU (1) | AU2022223712A1 (es) |
CA (1) | CA3211240A1 (es) |
CO (1) | CO2023010612A2 (es) |
IL (1) | IL305313A (es) |
MX (1) | MX2023009728A (es) |
TW (1) | TW202245836A (es) |
WO (1) | WO2022178196A1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11771652B2 (en) | 2020-11-06 | 2023-10-03 | Sanofi | Lipid nanoparticles for delivering mRNA vaccines |
WO2025126019A1 (en) * | 2023-12-13 | 2025-06-19 | Pfizer Inc. | Rna molecules |
Family Cites Families (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4695624A (en) | 1984-05-10 | 1987-09-22 | Merck & Co., Inc. | Covalently-modified polyanionic bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers, and methods of preparing such polysaccharides and conjugates and of confirming covalency |
GB8815795D0 (en) | 1988-07-02 | 1988-08-10 | Bkl Extrusions Ltd | Glazing bead |
CA2017507C (en) | 1989-05-25 | 1996-11-12 | Gary Van Nest | Adjuvant formulation comprising a submicron oil droplet emulsion |
PT761231E (pt) | 1992-06-25 | 2000-06-30 | Smithkline Beecham Biolog | Composicao de vacina contendo adjuvantes |
US5776468A (en) | 1993-03-23 | 1998-07-07 | Smithkline Beecham Biologicals (S.A.) | Vaccine compositions containing 3-0 deacylated monophosphoryl lipid A |
GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
US5494808A (en) | 1994-09-15 | 1996-02-27 | Merck & Co., Inc. | Defined medium OMPC fermentation process |
GB9513261D0 (en) | 1995-06-29 | 1995-09-06 | Smithkline Beecham Biolog | Vaccines |
CA2301575C (en) | 1997-05-20 | 2003-12-23 | Ottawa Civic Hospital Loeb Research Institute | Vectors and methods for immunization or therapeutic protocols |
GB9712347D0 (en) | 1997-06-14 | 1997-08-13 | Smithkline Beecham Biolog | Vaccine |
ES2298316T3 (es) | 1997-09-05 | 2008-05-16 | Glaxosmithkline Biologicals S.A. | Emulsiones de aceite en agua que contienen saponinas. |
US6303114B1 (en) | 1998-03-05 | 2001-10-16 | The Medical College Of Ohio | IL-12 enhancement of immune responses to T-independent antigens |
EP1069910A1 (en) | 1998-04-09 | 2001-01-24 | GlaxoSmithKline Biologicals S.A. | Adjuvant compositions |
GB9817052D0 (en) | 1998-08-05 | 1998-09-30 | Smithkline Beecham Biolog | Vaccine |
DE122007000087I1 (de) | 1998-10-16 | 2008-03-27 | Glaxosmithkline Biolog Sa | Adjuvanzsysteme und impfstoffe |
DE60038166T2 (de) | 1999-03-19 | 2009-03-12 | Glaxosmithkline Biologicals S.A., Rixensart | Impfstoff gegen bakterielle antigene |
CZ303515B6 (cs) | 1999-04-19 | 2012-11-07 | Smithkline Beecham Biologicals S. A. | Adjuvantní prostredek |
CZ20021045A3 (cs) | 1999-09-24 | 2002-08-14 | Smithkline Beecham Biologicals S. A. | Pomocný prostředek |
HUP0202885A3 (en) | 1999-09-24 | 2004-07-28 | Smithkline Beecham Biolog | Vaccines |
RU2304617C2 (ru) | 2000-02-28 | 2007-08-20 | Новартис Вэксинс Энд Диагностикс С.Р.Л. | Гибридная экспрессия белков neisseria |
CA2435681C (en) | 2001-01-23 | 2011-06-21 | Aventis Pasteur | Multivalent meningococcal polysaccharide-protein conjugate vaccine |
GB0121591D0 (en) | 2001-09-06 | 2001-10-24 | Chiron Spa | Hybrid and tandem expression of neisserial proteins |
MX339524B (es) * | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
AU2009221180B2 (en) | 2008-03-05 | 2014-02-13 | Sanofi Pasteur | Process for stabilizing an adjuvant containing vaccine composition |
GB0819633D0 (en) | 2008-10-25 | 2008-12-03 | Isis Innovation | Composition |
CA2779816A1 (en) | 2009-10-27 | 2011-05-05 | Novartis Ag | Modified meningococcal fhbp polypeptides |
AU2016273825A1 (en) * | 2009-10-27 | 2017-01-05 | Novartis Ag | Modified meningococcal fHBP polypeptides |
CN103002910A (zh) * | 2010-03-10 | 2013-03-27 | 葛兰素史密丝克莱恩生物有限公司 | 疫苗组合物 |
BR122021020829B8 (pt) | 2010-03-30 | 2022-12-27 | Children´S Hospital & Res Center At Oakland | Proteína de ligação ao fator h de ocorrência não natural (fhbp), composição, e célula hospedeira de neisseria meningitidis geneticamente modificada |
WO2011161653A1 (en) * | 2010-06-25 | 2011-12-29 | Novartis Ag | Combinations of meningococcal factor h binding proteins |
JP5976652B2 (ja) | 2010-09-10 | 2016-08-24 | ワイス・エルエルシー | 髄膜炎菌orf2086抗原の非脂質化変異体 |
JP6042816B2 (ja) | 2011-09-26 | 2016-12-14 | テルモ株式会社 | 液体注入具 |
KR101763625B1 (ko) | 2012-03-09 | 2017-08-01 | 화이자 인코포레이티드 | 수막염균 조성물 및 이의 사용 방법 |
AU2014296027A1 (en) | 2013-08-02 | 2016-02-04 | Children's Hospital & Research Center At Oakland | Non-naturally occurring factor H binding proteins (fHbp) and methods of use thereof |
SMT202000704T1 (it) | 2014-02-28 | 2021-01-05 | Glaxosmithkline Biologicals Sa | POLIPEPTIDI DI fHbp DI MENINGOCOCCO MODIFICATI |
EP3127572B1 (en) | 2014-03-31 | 2021-12-22 | Terumo Kabushiki Kaisha | Prefilled syringe |
BE1022641B1 (fr) | 2014-07-17 | 2016-06-23 | Glaxosmithkline Biologicals Sa | POLYPEPTIDES MENINGOCOCCIQUES fHbp MODIFIES |
BR112017001417B1 (pt) | 2014-07-23 | 2023-11-07 | Children's Hospital & Research Center At Oakland | Variantes da proteína de ligação ao fator h (fhbp), composição imunogênica e uso de uma fhbp variante referência cruzada |
EP3011990A1 (en) | 2014-10-21 | 2016-04-27 | Sulzer Mixpac AG | Dual-chamber syringe |
HRP20240433T1 (hr) | 2016-09-02 | 2024-07-05 | Sanofi Pasteur, Inc. | Cjepivo protiv neisseria meningitidis |
EP3607967A1 (en) | 2018-08-09 | 2020-02-12 | GlaxoSmithKline Biologicals S.A. | Modified meningococcal fhbp polypeptides |
CA3129425A1 (en) * | 2019-02-11 | 2020-08-20 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
-
2022
- 2022-02-18 IL IL305313A patent/IL305313A/en unknown
- 2022-02-18 MX MX2023009728A patent/MX2023009728A/es unknown
- 2022-02-18 JP JP2023550019A patent/JP2024507828A/ja active Pending
- 2022-02-18 CA CA3211240A patent/CA3211240A1/en active Pending
- 2022-02-18 KR KR1020237027927A patent/KR20230147075A/ko active Pending
- 2022-02-18 TW TW111105942A patent/TW202245836A/zh unknown
- 2022-02-18 AU AU2022223712A patent/AU2022223712A1/en active Pending
- 2022-02-18 WO PCT/US2022/016894 patent/WO2022178196A1/en active Application Filing
- 2022-02-18 US US17/674,932 patent/US12053516B2/en active Active
- 2022-02-18 EP EP22707000.0A patent/EP4294432A1/en active Pending
-
2023
- 2023-08-15 CO CONC2023/0010612A patent/CO2023010612A2/es unknown
-
2024
- 2024-06-18 US US18/746,742 patent/US20240415948A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
US20240415948A1 (en) | 2024-12-19 |
KR20230147075A (ko) | 2023-10-20 |
CA3211240A1 (en) | 2022-08-25 |
AU2022223712A9 (en) | 2024-02-22 |
US20220265805A1 (en) | 2022-08-25 |
TW202245836A (zh) | 2022-12-01 |
JP2024507828A (ja) | 2024-02-21 |
WO2022178196A1 (en) | 2022-08-25 |
EP4294432A1 (en) | 2023-12-27 |
US12053516B2 (en) | 2024-08-06 |
CO2023010612A2 (es) | 2023-09-08 |
IL305313A (en) | 2023-10-01 |
AU2022223712A1 (en) | 2023-10-05 |
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