CN108478596A - A kind of novel antibacterial anti-inflammatory acne eliminating cream and preparation method thereof - Google Patents

Abstract

The invention discloses a kind of novel antibacterial anti-inflammatory acne eliminating creams, including following each component：Hexadecanol, octadecyl alcolol, dimethicone, glycerin monostearate, lauryl sodium sulfate, glycerine, jojoba oil and Nano-Zinc.The dosage of Nano-Zinc is 0.2 4wt%.Water-soluble nano zinc is introduced into acne eliminating cream by the present invention, and numerous studies show that Nano-Zinc has anti-inflammatory, wrinkle resistant, protection and convergence function to skin; clinically often as the external used medicine of skin; significant effect, and without product dependence, without side effects such as allergic reactions, have a extensive future.

Description

Novel antibacterial, anti-inflammatory and acne-removing cream and preparation method thereof

technical field

The invention relates to the field of medicine for skin diseases, in particular to a novel antibacterial, anti-inflammatory and acne-removing cream and a preparation method thereof.

Background technique

Most people will suffer from acne, acne, acne and other skin diseases during the growth and development period. The main reason is that the inflammation of the skin is caused by inflammation. Agents that effectively inhibit microorganisms mean that inflammation can be effectively controlled. At present, there are many types and methods of acne removal on the market, such as VA ointment, clindamycin gel, dexamethasone cream, traditional Chinese medicine or plant essential oil, etc., but there will be problems such as drug dependence, skin tissue damage, and long treatment time .

Contents of the invention

The technical problem to be solved by the present invention is to overcome the defect of obvious side effects of long-term use of acne-removing products in the prior art, and provide a novel antibacterial, anti-inflammatory and acne-removing cream.

In order to solve the problems of the technologies described above, the present invention provides the following technical solutions:

A new type of antibacterial, anti-inflammatory and acne-removing cream, comprising the following components:

Cetyl Alcohol, Stearyl Alcohol, Simethicone, Glyceryl Monostearate, Sodium Lauryl Sulfate, Glycerin, Jojoba Oil and Nano Zinc. Preferably, the dosage of nano-zinc is 0.2-4wt%.

The preferred components meet the following proportions: cetyl alcohol 2-8g, stearyl alcohol 2-8g, sodium lauryl sulfate 1-5g, simethicone 10-30ml, glyceryl monostearate 5 -10g, glycerin 8-20ml, jojoba oil 1-5ml and nano zinc 0.2-4wt%.

Further, the dosage form of the medicine is cream. How to use: After washing your face with clean water or facial cleanser, take an appropriate amount of anti-acne cream to the affected area according to the size of the inflammation, and massage gently for 1 minute until the anti-acne cream is fully absorbed by the skin.

The preparation method of the novel antibacterial, anti-inflammatory and acne-removing cream comprises the following steps:

(1) Weigh the components of the oil phase: cetyl alcohol, stearyl alcohol, sodium lauryl sulfate and simethicone, and heat them in a water bath at 80°C to fully dissolve them;

(2) Weigh the components of the water phase: add glycerin, jojoba oil and nano-zinc to 80°C, heat in a water bath at 80°C to fully dissolve;

(3) Add the solution prepared in step (2) to step (1), stir well at a speed of 280-350 rpm/min, emulsify in a water bath at 80°C for 30 minutes, stop the water bath, and cool to room temperature.

Jojoba oil has the functions of moisturizing, preventing wrinkles and softening the skin; nano-zinc has a good antibacterial effect and is a hot spot in the research of antibacterial materials. As a new type of zinc source, it not only has good biocompatibility, but also has relatively Good biological activity and immune regulation ability and other characteristics. It is the first time that water-soluble nano-zinc is used in the preparation of acne cream. As an inorganic antibacterial material, it has excellent safety, durability, slow-release and chemical stability, and is easy to use. It has gained more and more important attention. application.

The beneficial effects achieved by the present invention are:

The present invention introduces water-soluble nano-zinc into the acne cream. A large number of studies have shown that nano-zinc has anti-inflammatory, anti-wrinkle, protective and astringent functions on the skin. It is often used as an external drug for the skin in clinical practice. The effect is remarkable and there is no product dependence. Sex, no allergic reactions and other side effects, broad application prospects.

Detailed ways

Preferred embodiments of the present invention are described below, and it should be understood that the preferred embodiments described here are only used to illustrate and explain the present invention, and are not intended to limit the present invention.

Example 1

A new type of antibacterial, anti-inflammatory and acne-removing cream, each component meets the following ratio: cetyl alcohol 2g, stearyl alcohol 2g, sodium lauryl sulfate 1g, simethicone oil 10ml, glyceryl monostearate 5g, Glycerin 8ml, jojoba oil 1ml and nanometer zinc 0.2wt% and water 80.8mL.

The preparation method of the novel antibacterial, anti-inflammatory and acne-removing cream comprises the following steps:

(1) Weigh the components of the oil phase: cetyl alcohol, stearyl alcohol, sodium lauryl sulfate and simethicone, and heat them in a water bath at 80°C to fully dissolve them;

(2) Weigh the components of the water phase: add glycerin, jojoba oil and nano-zinc to 80°C, heat in a water bath at 80°C to fully dissolve;

(3) Add the solution prepared in step (2) to step (1), stir thoroughly at a speed of 300rpm/min, emulsify in a water bath at 80°C for 30min, stop the water bath, and cool to room temperature.

Example 2

A new type of antibacterial, anti-inflammatory and acne-removing cream, each component meets the following ratio: cetyl alcohol 8g, stearyl alcohol 8g, sodium lauryl sulfate 5g, simethicone oil 30ml, glyceryl monostearate 10g, Glycerin 20ml, jojoba oil 5ml and nanometer zinc 4wt% and water 41mL.

The preparation method of this embodiment is the same as that of Embodiment 1.

Example 3

A new type of antibacterial, anti-inflammatory and anti-acne cream, each component meets the following ratio: cetyl alcohol 6g, stearyl alcohol 5g, sodium lauryl sulfate 3g, simethicone oil 20ml, glyceryl monostearate 8g, Glycerin 16ml, jojoba oil 3ml and nanometer zinc 2wt% and water 60mL.

The preparation method of this embodiment is the same as that of Embodiment 1.

The anti-acne cream of embodiment 1-3 is carried out clinical verification to 100 people respectively, after cleansing face sooner or later, smear anti-acne cream of the present invention, 200 routine patients' diet and living habits during smearing anti-acne cream of the present invention and smear this The same before the invention of acne cream; experimental results: 98% cured, 100% effective.

Cure: All the acne and acne marks on the face disappeared; Effective: The acne on the face disappeared, but the acne marks remained faint; Ineffective: The acne or acne marks on the face remained basically unchanged.

Wu, male, 15 years old, has a large area of pimples on his face. The pimples have been growing for two or three years. After ten days of applying the acne cream of this invention, the acne on Zhang’s face has basically disappeared. Continue to apply this invention to remove acne One week after the cream, the pimples and pimples on Zhang's face completely disappeared, and the acne marks were obviously lightened.

Li, male, 30 years old, has a lot of acne on his face. After applying the acne cream of the invention for two weeks, most of the acne on Li’s face disappeared. After continuing to apply the acne cream of the invention for a week, the acne on Li’s face The acne basically disappeared, leaving only a light acne mark.

Huang, female, 26 years old, has a large area of pustules on her face. The pustules have been there for six years. After three weeks of applying the acne cream of this invention, the pustules on her face have basically faded away, and she continues to apply the acne cream of this invention One month later, the pustules on Huang's face disappeared, leaving only faint acne scars.

Finally, it should be noted that: the above is only a preferred embodiment of the present invention, and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the foregoing embodiments, for those skilled in the art, it still The technical solutions recorded in the foregoing embodiments may be modified, or some technical features thereof may be equivalently replaced. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present invention shall be included within the protection scope of the present invention.

Claims (5)

1. A novel antibacterial, anti-inflammatory and acne-removing cream, characterized in that it comprises the following components: Cetyl Alcohol, Stearyl Alcohol, Simethicone, Glyceryl Monostearate, Sodium Lauryl Sulfate, Glycerin, Jojoba Oil, Nanozinc and Water. 2. novel antibacterial, antiphlogistic and acne removing cream as claimed in claim 1, is characterized in that, the consumption of nano-zinc is 0.2-4wt%. 3. novel antibacterial antiphlogistic anti-acne cream as claimed in claim 2, is characterized in that, comprises cetyl alcohol 2-8g, stearyl alcohol 2-8g, sodium lauryl sulfate 1-5g, simethicone 10g -30ml, 5-10g of glyceryl monostearate, 8-20ml of glycerin, 1-5ml of jojoba oil, 0.2-4wt% of nanometer zinc and an appropriate amount of water. 4. Novel antibacterial, anti-inflammatory and acne-removing cream as described in any one of claims 1-3, characterized in that, the dosage form of the medicine is a cream. 5. The preparation method of novel antibacterial, anti-inflammatory and acne-removing cream as claimed in claim 1, is characterized in that, comprises the following steps: (1) Weigh the components of the oil phase: cetyl alcohol, stearyl alcohol, sodium lauryl sulfate and simethicone, and heat them in a water bath at 80°C to fully dissolve them; (2) Weigh the components of the water phase: add glycerin, jojoba oil and nano-zinc to 80°C, heat in a water bath at 80°C to fully dissolve; (3) Add the solution prepared in step (2) to step (1), stir well at a speed of 280-350 rpm/min, emulsify in a water bath at 80°C for 30 minutes, stop the water bath, and cool to room temperature.