CN107028797A - Anti-acne essence and preparation method thereof - Google Patents
Anti-acne essence and preparation method thereof Download PDFInfo
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- CN107028797A CN107028797A CN201710435728.0A CN201710435728A CN107028797A CN 107028797 A CN107028797 A CN 107028797A CN 201710435728 A CN201710435728 A CN 201710435728A CN 107028797 A CN107028797 A CN 107028797A
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- 230000003255 anti-acne Effects 0.000 title claims abstract description 44
- 238000002360 preparation method Methods 0.000 title claims abstract description 11
- 239000011701 zinc Substances 0.000 claims abstract description 43
- 229910052725 zinc Inorganic materials 0.000 claims abstract description 43
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 36
- 229920002385 Sodium hyaluronate Polymers 0.000 claims abstract description 34
- 229940010747 sodium hyaluronate Drugs 0.000 claims abstract description 34
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims abstract description 34
- 229920001285 xanthan gum Polymers 0.000 claims abstract description 32
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims abstract description 30
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical class CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 claims abstract description 21
- 229940119170 jojoba wax Drugs 0.000 claims abstract description 19
- 235000011187 glycerol Nutrition 0.000 claims abstract description 18
- 235000019437 butane-1,3-diol Nutrition 0.000 claims abstract description 16
- 229930003427 Vitamin E Natural products 0.000 claims abstract description 15
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims abstract description 15
- 235000019165 vitamin E Nutrition 0.000 claims abstract description 15
- 229940046009 vitamin E Drugs 0.000 claims abstract description 15
- 239000011709 vitamin E Substances 0.000 claims abstract description 15
- 239000003755 preservative agent Substances 0.000 claims abstract description 8
- 230000002335 preservative effect Effects 0.000 claims abstract description 8
- 239000003002 pH adjusting agent Substances 0.000 claims abstract description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 64
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- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims description 17
- 229960005323 phenoxyethanol Drugs 0.000 claims description 17
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 claims description 16
- 239000011259 mixed solution Substances 0.000 claims description 16
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims description 15
- 229940058015 1,3-butylene glycol Drugs 0.000 claims description 10
- 239000012153 distilled water Substances 0.000 claims description 8
- 238000001223 reverse osmosis Methods 0.000 claims description 8
- 239000000243 solution Substances 0.000 claims description 8
- 238000003756 stirring Methods 0.000 claims description 8
- 239000012498 ultrapure water Substances 0.000 claims description 8
- 239000003795 chemical substances by application Substances 0.000 claims description 6
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims description 5
- -1 Metagin Ester Chemical class 0.000 claims description 4
- 230000003750 conditioning effect Effects 0.000 claims description 4
- AXPZIVKEZRHGAS-UHFFFAOYSA-N 3-benzyl-5-[(2-nitrophenoxy)methyl]oxolan-2-one Chemical compound [O-][N+](=O)C1=CC=CC=C1OCC1OC(=O)C(CC=2C=CC=CC=2)C1 AXPZIVKEZRHGAS-UHFFFAOYSA-N 0.000 claims description 3
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- GJCOSYZMQJWQCA-UHFFFAOYSA-N 9H-xanthene Chemical compound C1=CC=C2CC3=CC=CC=C3OC2=C1 GJCOSYZMQJWQCA-UHFFFAOYSA-N 0.000 description 3
- 208000002874 Acne Vulgaris Diseases 0.000 description 3
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- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 2
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- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0241—Containing particulates characterized by their shape and/or structure
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/27—Zinc; Compounds thereof
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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- A61K8/678—Tocopherol, i.e. vitamin E
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- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
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- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/413—Nanosized, i.e. having sizes below 100 nm
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- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
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- Dermatology (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Cosmetics (AREA)
Abstract
The present invention relates to anti-acne essence and preparation method thereof, the anti-acne essence is made up of the component of following percentage by weight：Xanthans：0.1% ~ 1%, water-soluble jojoba oil：0.5% ~ 3%, glycerine：1% ~ 10%, 1,3 butanediols：1% ~ 10%, watermiscible vitamin E：0.5% ~ 5%, Nano-Zinc：1% ~ 10%, Sodium Hyaluronate：0.1% ~ 1%, preservative：0.2% ~ 1.5%, pH adjusting agent：0.1% ~ 1%, essence：0.01% ~ 0.3%, Yi Jishui：Surplus；Each component sum is 100%.The anti-acne essence preparation technology of the present invention is simple, and prepared Nano-Zinc moisturizing anti-acne essence has preferable moistening effect and superior anti-acne effect, and product is gently non-stimulated, with good skin effect.
Description
Technical field
The present invention relates to a kind of Essence and preparation method thereof, belong to cosmetic field；More particularly, it relates to one
Plant anti-acne essence containing Nano-Zinc and preparation method thereof.
Background technology
With the quickening pace of modern life, work and the increase of life stress, along with environmental pollution and food security are asked
Topic takes place frequently, and the incidence of disease of whelk rises year by year.Whelk is a kind of common chronic pilosebaceous inflammations disease, good hair
In vigorous positions of sebum secretion such as face, shirtfront and upper backs, course of disease length, easily recurrence often show as Whiteheads, blackhead powder
Thorn or inflamed papules, serious has useless fellow, tubercle, tumour or scar.If inflammation substantially, can more cause pain or touch pain,
And with seborrhea, or even there is tangerine peel face.Whelk incidence in youth of both sexes crowd is high, and it not only has a strong impact on
Face it is attractive in appearance, and influence people social and psychology, make patient occur it is not self-confident, awkward, lose, anxiety, anxiety, irritability and
The negative emotions such as depression, so as to influence quality of life.
The cosmetics internal structure that traditional handicraft is obtained is micelle shape or micellelike, its a diameter of micron, to Cutaneous permeation
Ability is very weak, is difficult to be absorbed by epidermal cell.And skin outermost layer has hydrophobicity cuticula, thus water-soluble substances and big point
Sub- material is quite difficult by the absorption of epidermal absorption and pilosebaceous follicle.
The content of the invention
To overcome traditional handicraft cosmetics defect as described above, developed the invention provides a kind of use nanometer technology
Cosmetics, it can be suitable by composition specially treated most powerful in cosmetics into this extremely small structure of nanoscale
Profit penetrates to the skin internal layer, plays skin care with getting twice the result with half the effort, treats skin effect, the cosmetic defect obtained to traditional handicraft is carried out very
Good improvement.
In an aspect, the invention provides a kind of anti-acne essence, it is made up of the component of following percentage by weight：It is yellow
Virgin rubber：0.1% ~ 1%, water-soluble jojoba oil：0.5% ~ 3%, glycerine：1% ~ 10%, 1,3 butylene glycol：1% ~ 10%, water soluble vitamin is given birth to
Plain E：0.5% ~ 5%, Nano-Zinc：1% ~ 10%, Sodium Hyaluronate：0.1% ~ 1%, preservative：0.2% ~ 1.5%, pH adjusting agent：0.1%~
1%th, essence：0.01% ~ 0.3%, Yi Jishui：Surplus；Each component sum is 100%.
In a preferred embodiment, the preservative is methyl hydroxybenzoate 0.1% ~ 0.5% and Phenoxyethanol 0.1% ~ 1%.
In a preferred embodiment, the PH conditioning agents are triethanolamine.
In a preferred embodiment, anti-acne essence of the invention is made up of the component of following percentage by weight：Xanthan
Glue：0.25%th, water-soluble jojoba oil：1%th, glycerine：4%th, 1,3 butylene glycol：4%th, watermiscible vitamin E：1%th, Nano-Zinc：
2.7%th, Sodium Hyaluronate：0.1%th, methyl hydroxybenzoate：0.1%th, Phenoxyethanol：0.1%th, triethanolamine：0.15%th, essence：0.03%、
And water：86.57%.
In a preferred embodiment, anti-acne essence of the invention is made up of the component of following percentage by weight：Xanthan
Glue：0.9%th, water-soluble jojoba oil：3%th, glycerine：1%th, 1,3 butylene glycol：8%th, watermiscible vitamin E：4.7%th, Nano-Zinc：
1.5%th, Sodium Hyaluronate：1%th, methyl hydroxybenzoate：0.5%th, Phenoxyethanol：0.8%th, triethanolamine：0.86%th, essence：0.26%th, with
And water：77.48%.
In a preferred embodiment, anti-acne essence of the invention is made up of the component of following percentage by weight：Xanthan
Glue：0.5%th, water-soluble jojoba oil：0.8%th, glycerine：9.6%th, 1,3 butylene glycol：1.5%th, watermiscible vitamin E：2.3%th, nanometer
Zinc：9%th, Sodium Hyaluronate：0.6%th, methyl hydroxybenzoate：0.3%th, Phenoxyethanol：0.46%th, triethanolamine：0.45%th, essence：
0.17%th, Yi Jishui：74.32%.
In a preferred embodiment, the water is light water, high purity water, distilled water, reverse osmosis water or small-micelle water；
Preferably high purity water, distilled water, reverse osmosis water or small-micelle water；More preferably small-micelle water.
In another aspect, the invention provides a kind of preparation method of anti-acne essence, comprise the following steps：
Sodium Hyaluronate dissolves：Sodium Hyaluronate is weighed, plus Part I is water-swellable until it is completely dissolved；
Xanthans dissolves：Xanthans is weighed, plus Part II water is completely dissolved it；
Nano-Zinc is tentatively mixed：By water-soluble jojoba oil, glycerine, 1,3-BDO, watermiscible vitamin E, Nano-Zinc, anti-corrosion
Agent, pH adjusting agent are added in the water of remainder, at room temperature, are well mixed；
Mixing：The solution that Sodium Hyaluronate dissolving step and xanthans dissolving step are obtained is added to the preliminary mixing step of Nano-Zinc
Suddenly in the mixed solution obtained, stir；
Add essence：Essence is added in the mixed solution obtained to blend step, stirred, the anti-acne elite is obtained
Liquid.
In a preferred embodiment, the preservative is methyl hydroxybenzoate and Phenoxyethanol；The PH conditioning agents are three
Monoethanolamine.
In a preferred embodiment, mixing speed is 600-1000rpm；Preferably 600-800rpm；More preferably
700-800rpm。
Wherein, the water can be light water, high purity water, distilled water, reverse osmosis water or the small molecule such as running water
Group's water；Preferably high purity water, distilled water, reverse osmosis water or small-micelle water；More preferably small-micelle water.Small-micelle water has
There are high osmosis, high diffusibility and highly dissoluble, more moisture and nutrition can be brought into cell, while by waste and poisonous substance
Preferably discharge.Because small-micelle water more easily can be absorbed and be utilized by internal cell, so its biology utilization rate
It is more much higher than light water, the information transmission between efficiency and function, enhancing cell and the surrounding tissue of metabolism can be strengthened,
The transmission supply of nutrition of whole body material is obviously improved, transport capacity of whole body oxygen etc. is improved.
Nano-Zinc is a kind of multi-functional new inorganic material.Due to the granular of crystal grain, its Electronic Structure and
Crystal structure changes, and generates skin effect, bulk effect, quantum size effect and macroscopic view that macro object does not have
The features such as tunnel-effect and the high grade of transparency, polymolecularity.The outstanding feature of Nano-Zinc is that product pellet is nanoscale, simultaneously
Double grading with nano material and conventional oxidation zinc.Nanometer Zinc material heat endurance is good, can adsorb, suppresses and kill thin
Bacterium, the features such as with good anti-bacterial effect, timeliness length, safe, reasonable price, in oral anxious toxicity, skin irritatin, sensitiveness
Confirmed in experiment, with tight security and antimicrobial long-acting ability.
Nanometer zinc particles used in the present invention and preparation method thereof, will here by reference referring to CN104014814A
Entire contents are incorporated herein.The toner of the present invention, as active component, can be substituted existing using Nano-Zinc as described above
There is the active component in anti-acne toner in technology, and in the case of without being cooperated with other anti-acne active components,
Can just play that effect is more preferable and the effect of more comprehensive anti-acne, acne-removing significantly, it is quick, persistently, safety；And and skin
With good compatibility, it can be absorbed by the skin rapidly, it is safe, gentle, do not cause stimulation, allergy etc. to be reacted, skin does not have yet
Burden.Nano-Zinc active component in toner of the present invention can suppress the microbial growths such as bacterium, fungi, slow down even
Eliminate inflammation and complication caused by small pox.
Watermiscible vitamin E in Essence of the present invention can effectively antagonize free radical, suppress lipid peroxide generation, dispel
Chloasma；Suppress the activity of tyrosinase, so as to reduce melanin generation；It can also eliminate by external worlds such as ultraviolet, air pollutions
The excessive oxygen radical that factor is caused, plays and delays the effects such as light aging, prevention sunburn and suppression sunburn generation；Simultaneously
With oxidation resistant effect, promote sex hormone secretion.
Water-soluble jojoba oil in Essence of the present invention will not cause allergy and acne, and the component of it and sebum is approached,
With fairly good skin-friendly, Peppermint Extract can be helped；In addition, water-soluble jojoba oil also contains abundant vitamin, and phase
The pliability being a good, can be soft and nourishes skin, has effects that to nourish softening skin, while having free from worldly cares anti-oxidant
Property.Add 1,3 butylene glycol, glycerine and further enhance moisturizing, moisturizing effect；1,3 butylene glycol can increase Nano-Zinc simultaneously
Dissolubility.
Sodium Hyaluronate in Essence of the present invention can play the protection skin effect of uniqueness, can keep skin moisturizing light
It is sliding, fine and smooth tender, high resilience, the effect with wrinkle resistant, crease-resistant, beauty and health care and recovery skin physiology function.
Preservative in Essence of the present invention uses methyl hydroxybenzoate and Phenoxyethanol compounding use, can effectively improve
The antiseptic property of toner, extends pot-life of toner etc..
The Essence of the present invention is ultraviolet from Bergamot Mint Extract, dissolution angular embolization, suppression bacterial multiplication, reparation scar, resistance
Pigmentation, promotion anti-acne composition percutaneous absorbtion, promotion whelk wound after line, anti-inflammatory, antiallergy, anti-oxidant, moisturizing, anti-inflammatory
In terms of mouth healing, comprehensive and significant anti-acne effect is played, skin is recovered normally fine and smooth soft and smooth.After deactivation, whelk etc.
Symptom is uneasy to recur, and acne-removing is notable, quick, lasting, safety.The elite liquid preparing process of the present invention is simple, prepared
Anti-acne essence has preferable moistening effect and superior anti-acne effect, and product is gently non-stimulated, is imitated with good skin care
Really.
Embodiment
Embodiments of the invention will be hereafter further described, wherein, each embodiment is only that the present invention is exemplary
Embodiment, it is not intended to constitute limiting the scope of the invention.Those skilled in the art can according to explanation above with
And following description of the embodiments makes a variety of different improvement and deformation, it is without departing from spirit and substance of the present invention.
Accordingly, the scope of the present invention is intended merely to be defined by every claim scope claimed.
Embodiment 1：
Preparing for the anti-acne essence of the present embodiment is as follows：
Sodium Hyaluronate dissolves：0.1% Sodium Hyaluronate is weighed, it is water-swellable until it is completely dissolved with 10%；
Xanthans dissolves：0.25% xanthans is weighed, it is completely dissolved with 10% water；
Nano-Zinc is tentatively mixed：By 1% water-soluble jojoba oil, 4% glycerine, 4%1,3- butanediols, 1% watermiscible vitamin E,
2.7% Nano-Zinc, 0.1% methyl hydroxybenzoate, 0.1% Phenoxyethanol, 0.15% triethanolamine are added in 66.57% water, in room temperature
Under, it is well mixed in agitator, mixing speed is 600-1000rpm, preferably 800rpm；
Mixing：The solution that Sodium Hyaluronate dissolving step and xanthans dissolving step are obtained is added separately to Nano-Zinc and tentatively mixed
Close in the mixed solution that step is obtained, stir；
Add essence：0.03% essence is added in the mixed solution obtained to blend step, stirred, you can obtain this reality
Apply the anti-acne essence of example.
Embodiment 2：
Preparing for the anti-acne essence of the present embodiment is as follows：
Sodium Hyaluronate dissolves：1% Sodium Hyaluronate is weighed, it is water-swellable until it is completely dissolved with 15%；
Xanthans dissolves：0.9% xanthans is weighed, it is completely dissolved with 17% water；
Nano-Zinc is tentatively mixed：By 3% water-soluble jojoba oil, 1% glycerine, 8%1,3- butanediols, 4.7% watermiscible vitamin E,
1.5% Nano-Zinc, 0.5% methyl hydroxybenzoate, 0.8% Phenoxyethanol, 0.86% triethanolamine are added in 45.48% water, in room temperature
Under, it is well mixed in agitator, mixing speed is 600rpm；
Mixing：The solution that Sodium Hyaluronate dissolving step and xanthans dissolving step are obtained is added separately to Nano-Zinc and tentatively mixed
Close in the mixed solution that step is obtained, stir；
Add essence：0.26% essence is added in the mixed solution obtained to blend step, stirred, the present embodiment is obtained
Anti-acne essence.
Embodiment 3：
Preparing for the anti-acne essence of the present embodiment is as follows：
Sodium Hyaluronate dissolves：0.6% Sodium Hyaluronate is weighed, it is water-swellable until it is completely dissolved with 13%；
Xanthans dissolves：0.5% xanthans is weighed, it is completely dissolved with 15% water；
Nano-Zinc is tentatively mixed：By 0.8% water-soluble jojoba oil, 9.6% glycerine, 1.5%1,3- butanediols, 2.3% water soluble vitamin
Raw element E, 9% Nano-Zinc, 0.3% methyl hydroxybenzoate, 0.46% Phenoxyethanol, 0.45% triethanolamine are added in 46.32% water,
At room temperature, it is well mixed in agitator, mixing speed is 1000rpm；
Mixing：The solution that Sodium Hyaluronate dissolving step and xanthans dissolving step are obtained is added separately to Nano-Zinc and tentatively mixed
Close in the mixed solution that step is obtained, stir；
Add essence：0.17% essence is added in the mixed solution obtained to blend step, stirred, the present embodiment is obtained
Anti-acne essence.
Embodiment 4
Preparing for the anti-acne essence of the present embodiment is as follows：
Sodium Hyaluronate dissolves：0.5% Sodium Hyaluronate is weighed, it is water-swellable until it is completely dissolved with 10% subset；
Xanthans dissolves：0.3% xanthans is weighed, it is completely dissolved with 10% small-micelle water；
Nano-Zinc is tentatively mixed：By 2% water-soluble jojoba oil, 5% glycerine, 5%1,3- butanediols, 2% watermiscible vitamin E, 3%
Nano-Zinc, 0.2% methyl hydroxybenzoate, 0.2% Phenoxyethanol, 0.2% triethanolamine are added in 61.55% small-micelle water,
At room temperature, it is well mixed in agitator, mixing speed is 800rpm；
Mixing：The solution that Sodium Hyaluronate dissolving step and xanthans dissolving step are obtained is added separately to Nano-Zinc and tentatively mixed
Close in the mixed solution that step is obtained, stir；
Add essence：0.05% essence is added in the mixed solution obtained to blend step, stirred, you can obtain this reality
Apply the anti-acne essence of example.
Embodiment 5：
Preparing for the anti-acne essence of the present invention is as follows：
Sodium Hyaluronate dissolves：Weigh 0.9% Sodium Hyaluronate, with 15% subset it is water-swellable until its be completely dissolved；
Xanthans dissolves：1% xanthans is weighed, it is completely dissolved with 17% small-micelle water；
Nano-Zinc is tentatively mixed：By 3% water-soluble jojoba oil, 5% glycerine, 9%1,3- butanediols, the life of 4.8% water soluble vitamin
Plain E, 5% Nano-Zinc, 0.3% methyl hydroxybenzoate, 0.7% Phenoxyethanol, 0.9% triethanolamine are added to 37.15% small molecule
In group's water, at room temperature, it is well mixed in agitator, mixing speed is 600rpm；
Mixing：The solution that Sodium Hyaluronate dissolving step and xanthans dissolving step are obtained is added separately to Nano-Zinc and tentatively mixed
Close in the mixed solution that step is obtained, stir；
Add essence：0.25% essence is added in the mixed solution obtained to blend step, stirred, the present embodiment is obtained
Anti-acne essence.
Embodiment 6：
Preparing for the anti-acne essence of the present invention is as follows：
Sodium Hyaluronate dissolves：Weigh 0.7% Sodium Hyaluronate, with 14% subset it is water-swellable until its be completely dissolved；
Xanthans dissolves：0.5% xanthans is weighed, it is completely dissolved with 15% small-micelle water；
Nano-Zinc is tentatively mixed：By 0.8% water-soluble jojoba oil, 9.6% glycerine, 1% 1,3-BDO, 2.3% water
Soluble vitamin E, 9% Nano-Zinc, 0.3% methyl hydroxybenzoate, 0.4% Phenoxyethanol, 0.45% triethanolamine are added to
In 45.78% small-micelle water, at room temperature, it is well mixed in agitator, mixing speed is 1000rpm；
Mixing：The solution that Sodium Hyaluronate dissolving step and xanthans dissolving step are obtained is added separately to Nano-Zinc and tentatively mixed
Close in the mixed solution that step is obtained, stir；
Add essence：0.17% essence is added in the mixed solution obtained to blend step, stirred, the present embodiment is obtained
Anti-acne essence.
Wherein, water involved in embodiment 1-6 can be for example, the light water of running water etc., high purity water, distilled water,
Reverse osmosis water, small-micelle water etc.；Preferably high purity water, distilled water, reverse osmosis water；More preferably small-micelle water.
Claims (10)
1. a kind of anti-acne essence, it is characterised in that be made up of the component of following percentage by weight：Xanthans：0.1% ~ 1%, water
Dissolubility jojoba oil：0.5% ~ 3%, glycerine：1% ~ 10%, 1,3 butylene glycol：1% ~ 10%, watermiscible vitamin E：0.5% ~ 5%, nanometer
Zinc：1% ~ 10%, Sodium Hyaluronate：0.1% ~ 1%, preservative：0.2% ~ 1.5%, pH adjusting agent：0.1% ~ 1%, essence：0.01%~
0.3%th, Yi Jishui：Surplus；Each component sum is 100%.
2. anti-acne essence according to claim 1, it is characterised in that the preservative be methyl hydroxybenzoate 0.1% ~
0.5% and Phenoxyethanol 0.1% ~ 1%.
3. anti-acne essence according to claim 1 or 2, it is characterised in that the PH conditioning agents are triethanolamine.
4. the anti-acne essence according to any one of claims 1 to 3, it is characterised in that by the group of following percentage by weight
Divide and constitute：Xanthans：0.25%th, water-soluble jojoba oil：1%th, glycerine：4%th, 1,3 butylene glycol：4%th, watermiscible vitamin E：1%、
Nano-Zinc：2.7%th, Sodium Hyaluronate：0.1%th, methyl hydroxybenzoate：0.1%th, Phenoxyethanol：0.1%th, triethanolamine：0.15%th, it is fragrant
Essence：0.03%th, Yi Jishui：86.57%.
5. the anti-acne essence according to any one of claims 1 to 3, it is characterised in that by the group of following percentage by weight
Divide and constitute：Xanthans：0.9%th, water-soluble jojoba oil：3%th, glycerine：1%th, 1,3 butylene glycol：8%th, watermiscible vitamin E：
4.7%th, Nano-Zinc：1.5%th, Sodium Hyaluronate：1%th, methyl hydroxybenzoate：0.5%th, Phenoxyethanol：0.8%th, triethanolamine：0.86%、
Essence：0.26%th, Yi Jishui：77.48%.
6. the anti-acne essence according to any one of claims 1 to 3, it is characterised in that by the group of following percentage by weight
Divide and constitute：Xanthans：0.5%th, water-soluble jojoba oil：0.8%th, glycerine：9.6%th, 1,3 butylene glycol：1.5%th, water soluble vitamin
E：2.3%th, Nano-Zinc：9%th, Sodium Hyaluronate：0.6%th, methyl hydroxybenzoate：0.3%th, Phenoxyethanol：0.46%th, triethanolamine：
0.45%th, essence：0.17%th, Yi Jishui：74.32%.
7. the anti-acne essence according to any one of claim 1 to 6, it is characterised in that：The water is light water, high-purity
Water, distilled water, reverse osmosis water or small-micelle water；Preferably high purity water, distilled water, reverse osmosis water or small-micelle water；It is more excellent
Elect small-micelle water as.
8. the preparation method of a kind of anti-acne essence according to any one of claim 1 to 7, it is characterised in that including such as
Lower step：
Sodium Hyaluronate dissolves：Sodium Hyaluronate is weighed, plus Part I is water-swellable until it is completely dissolved；
Xanthans dissolves：Xanthans is weighed, plus Part II water is completely dissolved it；
Nano-Zinc is tentatively mixed：By water-soluble jojoba oil, glycerine, 1,3-BDO, watermiscible vitamin E, Nano-Zinc, anti-corrosion
Agent, pH adjusting agent are added in the water of remainder, at room temperature, are well mixed；
Mixing：The solution that Sodium Hyaluronate dissolving step and xanthans dissolving step are obtained is added to the preliminary mixing step of Nano-Zinc
Suddenly in the mixed solution obtained, stir；
Add essence：Essence is added in the mixed solution obtained to blend step, stirred, the anti-acne elite is obtained
Liquid.
9. the preparation method of anti-acne essence according to claim 8, it is characterised in that the preservative is Metagin
Ester and Phenoxyethanol；The PH conditioning agents are triethanolamine.
10. the preparation method of anti-acne essence according to claim 8 or claim 9, it is characterised in that mixing speed is 600-
1000rpm；Preferably 600-800rpm；More preferably 700-800rpm.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108186399A (en) * | 2018-02-14 | 2018-06-22 | 南京凯创协同纳米技术有限公司 | patch type facial mask and preparation method thereof |
| CN108420742A (en) * | 2018-05-15 | 2018-08-21 | 乌鲁木齐凯德道诚信息咨询服务有限公司 | A kind of cosmetic composition and preparation method thereof |
| CN108478596A (en) * | 2018-03-16 | 2018-09-04 | 江阴金泰克生物技术有限公司 | A kind of novel antibacterial anti-inflammatory acne eliminating cream and preparation method thereof |
| CN108852948A (en) * | 2018-09-19 | 2018-11-23 | 李燕 | A kind of Chinese medicine anti-acne essence and preparation method thereof |
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| CN105708718A (en) * | 2016-04-13 | 2016-06-29 | 广州丹奇日用化工厂有限公司 | Acne-removal cosmetic composition containing nano-zinc |
| CN106619380A (en) * | 2016-12-28 | 2017-05-10 | 广州市聚吉科绿色化学共性技术研究院有限公司 | Anti-acne essence |
| CN106726764A (en) * | 2016-12-25 | 2017-05-31 | 江西宜信堂医疗科技有限公司 | A kind of anti-acne essence and preparation method thereof |
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2017
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105708718A (en) * | 2016-04-13 | 2016-06-29 | 广州丹奇日用化工厂有限公司 | Acne-removal cosmetic composition containing nano-zinc |
| CN106726764A (en) * | 2016-12-25 | 2017-05-31 | 江西宜信堂医疗科技有限公司 | A kind of anti-acne essence and preparation method thereof |
| CN106619380A (en) * | 2016-12-28 | 2017-05-10 | 广州市聚吉科绿色化学共性技术研究院有限公司 | Anti-acne essence |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108186399A (en) * | 2018-02-14 | 2018-06-22 | 南京凯创协同纳米技术有限公司 | patch type facial mask and preparation method thereof |
| CN108478596A (en) * | 2018-03-16 | 2018-09-04 | 江阴金泰克生物技术有限公司 | A kind of novel antibacterial anti-inflammatory acne eliminating cream and preparation method thereof |
| CN108420742A (en) * | 2018-05-15 | 2018-08-21 | 乌鲁木齐凯德道诚信息咨询服务有限公司 | A kind of cosmetic composition and preparation method thereof |
| CN108852948A (en) * | 2018-09-19 | 2018-11-23 | 李燕 | A kind of Chinese medicine anti-acne essence and preparation method thereof |
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Application publication date: 20170811 |