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CN107303253A - It is a kind of to be used to be damaged renovation agent of skin and preparation method thereof - Google Patents

It is a kind of to be used to be damaged renovation agent of skin and preparation method thereof Download PDF

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Publication number
CN107303253A
CN107303253A CN201610251663.XA CN201610251663A CN107303253A CN 107303253 A CN107303253 A CN 107303253A CN 201610251663 A CN201610251663 A CN 201610251663A CN 107303253 A CN107303253 A CN 107303253A
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Prior art keywords
skin
water
extract
renovation agent
damaged
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Chinese (zh)
Inventor
方海
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Changsha Star Biotech Co Ltd
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Changsha Star Biotech Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/673Vitamin B group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/736Chitin; Chitosan; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/591Mixtures of compounds not provided for by any of the codes A61K2800/592 - A61K2800/596

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention discloses a kind of renovation agent for being used to be damaged skin, it is made up of the composition of following mass percent:Beta glucan 5 10;Propane diols 10 20;Golden yellow camomile extract 5 10;Purslane extract 5 10;Aloe extract 5 10;Chitosan 26;Panthenol 26;Sodium Hyaluronate 0.2 0.5;Oligopeptides 10.2 0.5;Allantoin 0.2 0.5;Water surplus.And the addition of composition is carried out by constantly cooling and thick liquid is stirred into, form the preparation method of renovation agent, so that the renovation agent modulated is to human body immunity of organisms, the threshold value repaired damaged cell, repair nerve end sheath in capillary, reduction skin, supplement and keep moisture of skin etc. solid type is multi-faceted to repair skin, skin is returned to health status.

Description

It is a kind of to be used to be damaged renovation agent of skin and preparation method thereof
Technical field
It is more particularly to a kind of to be used to be damaged repairing for skin the present invention relates to the field of skin-rehabilitating agent and preparation method thereof Multiple agent and preparation method thereof.
Background technology
Due to developing rapidly for China's economic in recent years, people's living standard increases rapidly, and goods and materials culture demand is also To huge raising, Cosmetic Market resulting in explosive growth.But also due to delayed, the supervision that state legal system is built Missing also result in international and domestic Cosmetic Market and occur in that larger lopsided development.Domestic skin care item city in 2015 according to statistics 300,000,000,000 RMB are up to, and the whitening share that segments market accounts for the 30% of whole skin care item market unexpectedly.Consumers in general are to U.S. The great demand of white product, the excessive pursuit along with consumer to fast onset product so that heavy metals exceeding standard in product swashs Element abuse phenomenon is protruded very much, and huge injury is caused to the vast white consumer that likes to be beautiful.Just because of the demand in market With the presence of the question of market, the skin expert and the top dermatologist in the several country of well-known universities and colleges in our the United Nations, warp After the experiment studied intensively with tens of thousands of times for many years, call on and studying a kind of renovation agent for being used to be damaged skin.
The content of the invention
The problem of the invention aims to solve to be previously mentioned in above-mentioned background technology, there is provided the system of high-purity zinc phosphide Preparation Method.
To achieve these goals, technical scheme is as follows:
A kind of renovation agent for being used to be damaged skin, is made up of the composition of following mass percent:
Beta glucan 5-10;
Propane diols 10-20;
Golden yellow camomile extract 5-10;
Purslane extract 5-10;
Aloe extract 5-10;
Chitosan 2-6;
Panthenol 2-6;
Sodium Hyaluronate 0.2-0.5;
The 0.2-0.5 of oligopeptides -1;
Allantoin 0.2-0.5;
Water surplus.
Further, it is made up of the composition of following mass percent:
Beta glucan 5-9;
Propane diols 10-18;
Golden yellow camomile extract 5-8;
Purslane extract 5-8;
Aloe extract 5-8;
Chitosan 3-6;
Panthenol 3-6;
Sodium Hyaluronate 0.3-0.5;
The 0.2-0.4 of oligopeptides -1:
Allantoin 0.2-0.4;
Water surplus.
Further, it is made up of the composition of following mass percent:
Beta glucan 5;
Propane diols 10;
Golden yellow camomile extract 5;
Purslane extract 5;
Aloe extract 5;
Chitosan 5;
Panthenol 3;
Sodium Hyaluronate 0.3;
Oligopeptides -1 0.2;
Allantoin 0.2;
Water surplus.
A kind of preparation method for being used to be damaged the renovation agent of skin, including the above-mentioned composition original matched according to mass percent Material, comprises the following steps:
A, take appropriate pure water be heated to 100 DEG C be incubated more than 30 minutes;
B, by the high-temperature-hot-water water cooling obtained through step a to 60-75 DEG C, the propane diols of formula ratio, transparent straight sour sodium are added Enter into 60-70 DEG C of hot water, stir, be allowed to dissolving complete:
C, 60-70 DEG C of the water obtained in step b is continued to be cooled to 50-55 DEG C, add the allantoin of formula ratio, stirring Dissolving is complete.
D, 50-55 DEG C of the water obtained in step c is continued to be cooled to 40-45 DEG C, add the golden yellow chamomile of formula ratio Extract, purslane extract, beta glucan, chitosan, panthenol, oligopeptides -1, aloe extract, are stirred and evenly mixed sticky to occurring Liquid;
E, the obtained thick liquids of step d are cooled to 30 DEG C or so dischargings;
F, the thick liquid that e is obtained is dispensed with vial after sealing preserve obtain required product.
The preparation method according to claim 4 for being used to be damaged the renovation agent of skin, it is characterised in that in step b, Sodium Hyaluronate is added in propane diols, and after being uniformly dissolved, in the water for adding 60-70 DEG C, stirred.
Optimum condition in this preparation technology is:Excellent 5 times for extract gross mass of the water of addition;The heating of pure water Excellent temperature is 100 DEG C, and excellent soaking time is 60min;The addition temperature of Sodium Hyaluronate is 70 DEG C, the water temperature during addition of extract Excellent is 45 DEG C, and excellent mixing time is 30min.
The prescription and function in agent prescription are repaired in the present invention
1. beta glucan
The polysaccharide that beta glucan active structure is made up of glucose unit, most of they are combined by β -1,3, this It is the mode of grape sugar chain connection.It can activated macrophage, neutrophils etc., therefore leukin can be improved, it is thin The content of born of the same parents' mitogen and distinct antibodies, stimulates the immune system of body comprehensively.So, body, which just has, is more ready to resistance Disease caused by microorganism.Beta glucan can make the ability of the lymphocyte generation cell factor (IL-1) of injured body extensive rapidly It is multiple normal, effectively adjust human body immune function.Many experiments show that beta glucan can promote the generation of internal IgM antibody, to carry The immunocompetence of high body fluid.The cell of this glucan activation can excite the non-specific defense mechanism of host, thus apply tumour, Infection disease attracts attention deeply with treatment trauma aspect is controlled.Extracted through specific step and without endotoxic β -1,3- glucans in the U.S. It is a kind of safe material that FDA, which has assert, can be added in normal food, and many reports show that oral yeast β -1, the 3- Portugals of mouse gather Sugar, can increase the phagocytosis of strong peritoneal cell antibacterial.In addition, glucan still has removing free radical, radioresistance, dissolving courage to consolidate Alcohol, infection caused by the effect of prevention hyperlipidemia and resistance filterable virus, fungi, bacterium etc..
It mainly has following remarkable efficacy:
A improves the ability of the infection such as body resistance virus, bacterium.
The Tiny ecosystem of the effective adjusting body digested roads of b, promotes the excretion of nuisance in the propagation and enteron aisle of internal beneficial bacterium.
C can reduce internal cholesterol level, it is possible to decrease internal low-density lipoprotein content, and increase HDL Content.
D is effectively improved impression of the distal tissues to insulin, reduces the requirement to insulin, promotes glucose to recover just Often, there is obvious suppress and prevention effect to diabetes.
E stimulates Skin Cell activity, strengthens the immunity protection function of skin itself, and efficient repairing sheath skin reduces skin wrinkle Line is produced, delay skin aging.
F strengthens animal to the resistivity of germ, promotes it to grow, and improves the production performance and efficiency of feed utilization of animal.
It was found that yeast dextran is primarily present in yeast cell wall, it is β (1 → 3) glucan, side that its main chain, which is combined, Chain is β (1 → 6) glucan, and this structure is different from the linear molecule structure of general carbohydrate, but a kind of unique triple ultra micros Helical structure.Its this special ultra micro helical molecule structure is the form that immunocompetence is most strong and is most easily absorbed by the body.
2. allantoin
Allantoin sterling is a kind of nontoxic, tasteless and nonirritant, without hypersensitive white crystal, and crystallization is single rib in water Cylinder or colorless crystalline powder.Hot water, hot alcohol and diluted sodium hydroxide solution can be dissolved in.It is slightly soluble in the water and alcohol of normal temperature, indissoluble In the organic solvent such as ether and chloroform;Its saturated aqueous solution (concentration is 0.6%) is in subacidity;PH is 5.5.It is 4-9 in pH value The aqueous solution in it is stable.Also stablize in nonaqueous solvents and dry air;Boiled in strong alkali solution and solar exposure under can Decompose.
A is in terms of medicine:Allantoin, which has, promotes cell growth, quickening wound healing, the physiological function such as cutin-softening albumen, is The good consolidant and antiulcer agents of skin trauma.Can be used as alleviating and treat xerodermia, scaling skin illness, skin Ulcer, digestive tract ulcer and inflammation, have good therapeutic effect to osteomyelitis, diabetes, hepatic sclerosis, acne.
B is in terms of cosmetics:Because allantoin is a kind of amphoteric compound, many kinds of substance formation double salt can be combined, is had Lucifuge, sterilization and anticorrosion, analgesic, antioxidation, can make skin keep moisture content, moisten and soft, are the cosmetics such as cosmetology Additive, be widely used in freckle cream, anti-acne toner, shampoo, perfumed soap, toothpaste, shaving lotion, conditioner, astringent, anti-sweat The additive of deodorization lotion etc..The cosmetics of addition allantoin have protective tissue, it is hydrophilic, absorb water and prevent moisture from distributing etc. and make With;Hair-cream, hair cream, the shampoo of allantoin are added, has protective effect to hair, hair not bifurcated, constantly hair can be made;Addition urine Lipstick, the face cream of Bursin can make skin, lip soft and high resilience, and have the gloss of beauty.Allantoin promotion organization grows, Cell metabolism, cutin-softening layer albumen.For example the softening angle of gentle Exfoliating Scrub lip film is moistened in the nursing of magic care magics The function of matter, moisturizing and increase gloss is exactly mainly the effect of allantoin.
3. chamomile
Chamomile is just considered as " god flower " from ancient times, with good Shu Min, the sensitive skin of maintenance, reduces thin red blood silk, subtracts Few rubescent, adjustment unequal effect of the colour of skin, but simultaneously not all chamomile can be used for beauty aspect at present.Chamomile is rich in flavones Active component, the composition has anti-oxidant, antiangiogenic, anti-inflammatory, anti-allergy and antiviral effect, passes through Issofree technologies can be extracted to chamomile active component and be applied to the high-end skin care item of anti-sensitive kinds.Beauty plus sweet smell are thought Cotton pads soak is used, rubescent skin can be quickly pacified.There is good soothing effect to the skin easily itched;Gently keep the skin wet, relax Slow skin.
4. Sodium Hyaluronate (sodium hyaluronate)
The straight chain polymer polysaccharide that sodium hyaluronate is made up of dissacharide units (glucuronic acid-N- second sulphur aminoglucose), is one Plant the material of naturally occurring in tissue.Sodium hyaluronate is largely present in the connective tissue of human body and skin corium, is a kind of transparent Colloid substance, with powerful moisture-keeping functions, 1 g of sodium hyaluronate can absorb 500C.C moisture, equivalent to 500 times of glycerine Water absorbing capacity.Universally present in the connective tissue of vertebrate, mucous tissue, the crystalline lens of eyeball and some in nature In the folder film of bacterium, the key player of matrix is played in the skin corium of human skin,
A is the biochemical drug with higher clinical value, is widely used in all kinds of ophthalmologic operations, such as Lens implantation, cornea Transplanting and resisting glaucoma operation etc..It can be additionally used in treatment of arthritis and accelerating wound healing.Use it in cosmetics, can play Unique protection skin effect, can keep skin moisturizing smooth, and fine and smooth tender, high resilience is protected with wrinkle resistant, crease-resistant, beauty Effect that is strong and recovering skin physiology function.
B. purposes can be used in the products such as cream, frost, honey, milk, facial mask, the shampoo of cosmetics, to keep skin, hair Moisture, skin care, hair increase gloss, and can prevent the generation of chapped skin and wrinkle.
Moisturizing is the first step of skin care, and the moisture content of healthy skin should maintain 15~20% or so, sodium hyaluronate Moistening effect be 16 times of collagen, water retention value, up to 1000cc/g, is the optimal moisturizer generally acknowledged in current document, Because sodium hyaluronate can make skin maintain health status for a long time, therefore it is referred to as " optimal moisturizing factor ".
C keeps elasticity of skin:Oral sodium hyaluronate is absorbed after moisture so that elastic fibers and collagen are in full of moistening Environment in, the collagen for the collagen synthesis itself of external supplement provides suitable environment, improves collagen Therefore utilization rate, skin be provided with elasticity.The effect of sodium hyaluronate also just embodies out.
D water conservations, water lock ability:The most important effect of sodium hyaluronate is exactly water conservation, water lock.Oral sodium hyaluronate can be pinned largely Hydrone, can not only keep the moisture in skin, moreover it is possible to catch the moisture of external environment, allow skin to be maintained at wet for a long time In the state of profit, strengthen the water holding capacity of skin.
5. aloe
Material needed for aloe contains 75 kinds of elements, with human body cell almost fits like a glove, and has obvious health value, quilt People's honor is referred to as " magical plant ", " first-aid kit for domestic use ".
A anti-agings:Mucus (mucm is exactly protein) in aloe, is with arboran A Baloe The polysaccharides such as mannanaloetin are nucleus, and mucus class material is to prevent cell senescence and treat the important of chronic allergic Composition.Mucoitin is present in muscle and gastrointestinal mucosa of human body etc., allows tissue high resilience, if liquid element is not enough, muscle and Mucous membrane will lose elasticity and stiff aging.The cell of human body is constituted, if mucoitin is not enough, cell will be gradually weak, Lose defence germ, the ability of virus.In addition, mucoitin also has strong body, strong essence effect.
B promotes healing:Hindering mouse back of the body aloe to artificial plane has promotion healing effect, and the rabbit aloe of artificial conjunctiva oedema can be contracted Short curative day.Aloe juice preparation has protective effect to skin trauma, burn and x line local irradiations.
C cardiac stimulants are invigorated blood circulation:Isocitric acid calcium in aloe etc. has cardiac stimulant, stimulates circulation, softens pipe-stem arteries, reduction Cholesterol level, the effect for expanding capillary.Make blood circulation unimpeded, reduce cholesterol value, mitigate heart burden, make blood pressure Keep normal, remove " toxin " in blood.
D is immune and regenerates:Aloin A, wound hormone and glycan peptide sweet dew (Ke-2) etc. have viral infection resisting, promote wound Mouthful healing restore effect, have anti-inflammation and sterilization, heat absorption detumescence, softening skin, keep cell viability function, curdlan be cured Wound acid joint also has healing plane wound activity.
E beautifying face and moistering lotions:The polysaccharide and multivitamin contained in aloe has good nutrition to human body skin, moistens, brightens Effect.Aloe barbadensis Miller is the Fresh leaf of aloe of the direct beauty of optimum, i.e. aloe barbadensis Miller, it have make skin contraction, softness, Moisturizing, anti-inflammatory, the performance of bleaching.Also release hardening, angling, improve the effect of scar.Can not only prevent small wrinkle, pouch, Cutis laxa, moreover it is possible to keep skin wet, tender and lovely.At the same time it can also treat scytitis, to acne, freckle, acne and Scald, knife wound, insect bite etc. also have good curative effect.It is similarly effective to hair, hair can be made to keep moistening smooth, pre-Anti-hair loss
6. chitosan
Chitosan (chitosan) is also known as chitosan, is youngster's fourth matter (chitin) warp being widely present by nature Cross what deacetylation was obtained, chemical name is Chitosan (1-4) -2- amino-B-D glucose.Chitosan and its derivative Thing has preferable antibacterial activity, can suppress the growth and breeding of some fungies, bacterium and virus.Thought that it could by the end of 2013 The mechanism of energy has three:One is due to the polycation of chitosan, it is easy to the negatively charged group effect of fungal cell surface, from And change the mobility and permeability of pathogen cell membrane:Two be the duplication and transcription for disturbing DNA, and three be to block pathogen generation Thank.
It is composition used in current senior medicine adornment that chitosan, which is acted on skin care item, used in pulsed light, radio frequency, dot matrix, fruit The postoperative natural antibiotics that play a part of of the medical cosmetologies such as acid come antiallergic sense and anti-inflammatory generation, quick to repair substrate fire damage, Quick healing of wound, repairs epidermal barrier, and the skin care item of chitosan wherein also have the effect for being metabolized heavy metal.
With the function such as good moisture absorption, moisturizing, conditioning, antibacterial:Suitable for skin cream, shower lotion, mildy wash, mousse, High-grade cream, emulsion, colloid cosmetics etc..
7. oligopeptides -1
A kind of classification of polypeptide, molecular weight section is general below 1000 dalton, also referred to as small peptide, oligopeptides, oligopeptide, or Referred to as small active peptides, are typically made up of 2--6 amino acid, and what is exceeded is known as polypeptide, and amino acid is more than more than 50 Polypeptide is referred to as protein.Difference with other peptides is to be not required to digestion in human body, you can directly absorbed.Oligopeptides can be divided into again:It is few Peptide -1, oligopeptides -3, oligopeptides -5 etc., oligopeptides -6 are also known as hexapeptide or Argireline.
Oligopeptides -1, also known as epithelical cell growth factor, are a kind of active material in human body, the work being made up of 53 amino Property polypeptide, by stimulate EGFR tyrosine phosphorylation, reach repairing hyperplasia skin surface cell, according to Say and excellent curative effect is possessed to injured, impaired epidermis skin.Its maximum feature is can to promote the Proliferation, Differentiation of cell, so that Aging and dead cell are replaced with newborn cell.EGF can also stop blooding, and with skin and mucous membrane wound healing is accelerated, disappear Inflammation analgesia, prevents effect of ulcer.EGF stability is fabulous, and flowing of scattering is difficult at normal temperatures, can be with various enzymes in human body Form good coordinating effect.Initial EGF is mainly employed for medical domain, be primarily to facilitate the reparation of impaired epidermis with Regeneration, such as treatment burn, scald.
EGF pore refinings, crease-resistant effect are very notable, and reason is that EGF can promote various kinds of cell in epidermal cell tissue Growth division, makes epidermal cell become full, recover younger state, it can also promote collagen growth ability, repairs old Change the collagen elastomer of fracture, so being described as " the beautiful factor " by numerous scientists.But early stage EGF yield is few, often Gram nearly 2,000,000 dollars of price, greatly limit applications of the EGF in beauty treatment fields.1992, U.S. James's drug study room will EGF is added in cosmetics, starts the biological beauty frontier that removing wrinkle and resisting aging is carried out with EGF, indicates biological gene beauty The arrival in epoch.
EGF can promote human body skin quickly to update, it is well known that woman's age is smaller, and skin is better, more pale tender and lovely, Its root original is exactly that the age is smaller, and EGF contents are higher in skin, and skin renewal speed is faster, and such skin is just tender and lovely, but with EGF content also progressively declines in the increase at age, skin, after 25 years old, declines faster, such skin is with regard to aging, coarse, heavy Shallow lake color spot, therefore EGF content, determine whether skin is tender and lovely, so EGF is also referred to as the beautiful factor by people.
8. panthenol
Panthenol, also known as dexpanthenol, dexpanthenol yellow to water white transparency thick liquid.Dexpanthenol can promote Human body protein, fat, the metabolism of carbohydrate, protection skin and mucous membrane, improve chroma of hair and gloss, prophylactic generation.
Contribute to wound healing:Antibody resistance infectious disease can be manufactured;Treat postoperative shock;Prevent fatigue;Alleviate a variety of The toxic side effect of antibiotic.
Provitamin B-5 is a kind of permeability NMF, tool deep moisturizing effect, can pass through skin, keep hair and skin Moisture in skin;Energy nutrition hair and skin, make skin lubrication, resist drying, cracking, and hair is bright, not easy entanglement.Provitamin B-5 is a kind of excellent skin and hair-protecting agent, can stimulate the division growth of cell, and the hyperplasia of augmentor fiber sprout cell has The function of repairing skin tissue, tool anti-inflammatory and the effect for the superficial wound that heals are assisted, and other composition (surfaces in formula can be mitigated Activating agent etc.) stimulating and the damage to hair to skin.Have uvioresistant, sun-proof effect.It is widely used in face and body On the Essence, face cream and the emulsion that use, lipstick and hair product, such as shampoo, hair conditioner, Rinsing hair-strengthening agent, mousse and spray Mist hair mousse.
9. purslane
Li Shizhen (1518-1593 A.D.)《Compendium of Materia Medica》It is early on the books.Purslane has the effect of the clearing heat and detoxicating Xiaoyan San stasis of blood, and to treat The diseases such as bacillary dysentery, enteritis and infantile erysipelas, effect is especially pronounced, that is to say, that it is natural antibiotic.Also have outside first with Lower effect:
A beauty, antiobesity action, anti-aging:Purslane also contains a large amount of vitamin Es, vitamin C, carrotene and glutathione Etc. the active ingredient of anti-aging.Chinese scholar He Shengwen etc. shows that purslane can improve rabbit body antioxygen by zoopery Change ability, reduces Serum MDA (MDA) content, the important function with anti-aging.
B eliminates pigmented spots:In addition, vitamin C has certain elimination pigmented spots effect, and vitamin E can be with protective wire grain The phosphatide of body, there is anti-radical action, is cosmetic good merchantable brand.
C medicine for curing poliosis:Purslane is higher (21 microgram/100 gram) containing copper, and copper ion is tyrosinase in vivo Important component, shortage can cause melanin generation reduction, cause white hair to increase.So, epidermis can be increased by often eating purslane The density of middle black cell and the activity of relevant enzyme, make white hair blackening.
D purslanes can control skin disease:Purslane enters the heart channel of Hang-Shaoyin, can with clearing away the heart-fire, enter lung channel, lung heat can be dissipated.《In Yellow Emperor, a legendary ruler Through》Say:All sufferings sores, come under the heart.And lung governing skin and hair.That is various carbuncle swells, ulcer, wet tinea, all have with internal heat and lung heat Close.Purslane both clearing away the heart-fire, dissipate lung heat again, and its toxin expelling effect both walks blood system, skin, internal and external application, so for upper are walked again Skin problem described in face is all effective in cure.Conditioning skin disease, can take orally and be worked along both lines with external application, fresh purslane is mashed Apply in affected part, or bathed with dry product is to boil water, be all well and good method.
Skin refers to tissue of the body surface bag outside muscle, is the maximum organ of human body, mainly carries protection body Body, perspire, feel the functions such as cold and hot and pressure.Skin covers whole body, and it makes various in vivo organize with organ from physical, machine Tool, invasion and attack chemically with pathogenic microorganism.The skin of people and higher mammal by epidermis, corium (mesoderm), subcutaneous group Knit up of three layers.
Damaged skin refers to a kind of state for causing skin injury due to external environment or external force, so as to occur as soon as example Such as red blood silk, sensitive skin, rubescent various situations of itching.The present invention is formed by being modulated according to a certain percentage to above composition Renovation agent to human body immunity of organisms, the threshold value repaired damaged cell, repair the last sheath of nerve in capillary, reduction skin, Supplement and keep moisture of skin etc. solid type is multi-faceted to repair skin, skin is returned to health status.
Embodiment
Technical scheme in the embodiment of the present invention is clearly and completely described, it is clear that described embodiment is only It is a part of embodiment of the invention, rather than whole embodiments.Based on the embodiment in the present invention, ordinary skill people The every other embodiment that member is obtained under the premise of creative work is not made, belongs to the scope of protection of the invention.
Embodiment 1
A kind of renovation agent for being used to be damaged skin, is made up of the composition of following mass percent:
Beta glucan 5;
Propane diols 10;
Golden yellow camomile extract 5;
Purslane extract 5;
Aloe extract 5;
Chitosan 5;
Panthenol 3;
Sodium Hyaluronate 0.3;
Oligopeptides -1 0.2;
Allantoin 0.2;
Water surplus.
Specific method step is as follows:
A, take appropriate pure water be heated to 100 DEG C be incubated 60 minutes;
B, by the high-temperature-hot-water water cooling obtained through step a to 70 DEG C, by the propane diols of formula ratio, transparent straight sour sodium add to In 70 DEG C of hot water, stir, be allowed to dissolving complete;
C, obtained in step b 70 DEG C of water is continued to be cooled to 55 DEG C, add the allantoin of formula ratio, stirring and dissolving is complete Entirely.
D, obtained in step c 55 DEG C of water is continued to be cooled to 45 DEG C, add formula ratio golden yellow camomile extract, Purslane extract, beta glucan, chitosan, panthenol, oligopeptides -1, aloe extract, are stirred and evenly mixed to there is thick liquid;
E, the obtained thick liquids of step d are cooled to 30 DEG C or so dischargings;
F, the thick liquid that e is obtained is dispensed with vial after sealing preserve obtain required product.
In the present invention, Sodium Hyaluronate is added in propane diols, and after being uniformly dissolved, in the water for adding 60-70 DEG C, stirring Uniformly.
Embodiment 2
A kind of renovation agent for being used to be damaged skin, is made up of the composition of following mass percent:
Beta glucan 6;
Propane diols 15;
Golden yellow camomile extract 7;
Purslane extract 7;
Aloe extract 7;
Chitosan 4;
Panthenol 4;
Sodium Hyaluronate 0.3;
Oligopeptides -1 0.2;
Allantoin 0.2;
Water surplus.
Specific method step is as follows:
A, take appropriate pure water be heated to 100 DEG C be incubated 50 minutes;
B, by the high-temperature-hot-water water cooling obtained through step a to 65 DEG C, by the propane diols of formula ratio, transparent straight sour sodium add to In 65 DEG C of hot water, stir, be allowed to melt complete;
C, obtained in step b 65 DEG C of water is continued to be cooled to 50 DEG C, add the allantoin of formula ratio, stirring and dissolving is complete Entirely.
D, obtained in step c 50 DEG C of water is continued to be cooled to 45 DEG C, add formula ratio golden yellow camomile extract, Purslane extract, beta glucan, chitosan, panthenol, oligopeptides -1, aloe extract, are stirred and evenly mixed to there is thick liquid;
E, the obtained thick liquids of step d are cooled to 30 DEG C or so dischargings;
F, the thick liquid that c is obtained is dispensed with vial after sealing preserve obtain required product.
In the present invention, Sodium Hyaluronate is added in propane diols, and after being uniformly dissolved, in the water for adding 60-70 DEG C, stirring Uniformly.
Presently preferred embodiments of the present invention is the foregoing is only, is not intended to limit the invention, all protection models in the present invention Interior made any modification, equivalent substitution etc. are enclosed, be should be included in the scope of the protection.

Claims (5)

1. a kind of renovation agent for being used to be damaged skin, it is characterised in that be made up of the composition of following mass percent:
Beta glucan 5-10;
Propane diols 10-20;
Golden yellow camomile extract 5-10;
Purslane extract 5-10;
Aloe extract 5-10;
Chitosan 2-6;
Panthenol 2-6;
Sodium Hyaluronate 0.2-0.5;
The 0.2-0.5 of oligopeptides -1;
Allantoin 0.2-0.5;
Water surplus.
2. according to claim 1 be used to be damaged the renovation agent of skin, it is characterised in that by following mass percent into It is grouped into:
Beta glucan 5-9;
Propane diols 10-18;
Golden yellow camomile extract 5-8;
Purslane extract 5-8;
Aloe extract 5-8;
Chitosan 3-6;
Panthenol 3-6;
Sodium Hyaluronate 0.3-0.5;
The 0.2-0.4 of oligopeptides -1;
Allantoin 0.2-0.4;
Water surplus.
3. according to claim 2 be used to be damaged the renovation agent of skin, it is characterised in that by following mass percent into It is grouped into:
Beta glucan 5;
Propane diols 10;
Golden yellow camomile extract 5;
Purslane extract 5;
Aloe extract 5;
Chitosan 5;
Panthenol 3;
Sodium Hyaluronate 0.3;
Oligopeptides -1 0.2;
Allantoin 0.2;
Water surplus.
4. a kind of preparation method for being used to be damaged the renovation agent of skin, including as in claim 1-3 any one according to matter Measure the component materials of percentage proportioning, it is characterised in that comprise the following steps:
A, take appropriate pure water be heated to 100 DEG C be incubated more than 30 minutes;
B, by the high-temperature-hot-water water cooling obtained through step a to 60-75 DEG C, by the propane diols of formula ratio, transparent straight sour sodium add to In 60-70 DEG C of hot water, stir, be allowed to dissolving complete;
C, 60-70 DEG C of the water obtained in step b is continued to be cooled to 50-55 DEG C, add the allantoin of formula ratio, stirring and dissolving Completely.
D, 50-55 DEG C of the water obtained in step c is continued to be cooled to 40-45 DEG C, the golden yellow chamomile for adding formula ratio is extracted Thing, purslane extract, beta glucan, chitosan, panthenol, oligopeptides -1, aloe extract, are stirred and evenly mixed to there is viscous fluid Body;
E, the obtained thick liquids of step d are cooled to 30 DEG C or so dischargings;
F, the thick liquid that e is obtained is dispensed with vial after sealing preserve obtain required product.
5. the preparation method according to claim 4 for being used to be damaged the renovation agent of skin, it is characterised in that in step b, will Sodium Hyaluronate is added in propane diols, and after being uniformly dissolved, in the water for adding 60-70 DEG C, is stirred.
CN201610251663.XA 2016-04-22 2016-04-22 It is a kind of to be used to be damaged renovation agent of skin and preparation method thereof Pending CN107303253A (en)

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Application Number Priority Date Filing Date Title
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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110393690A (en) * 2019-08-07 2019-11-01 义乌市安彤医药科技有限公司 A kind of maintenance essence and preparation method thereof slowing down skin saccharification
CN111643716A (en) * 2020-05-26 2020-09-11 海南芬森医疗器械有限公司 Scar nursing dressing and preparation method thereof
CN111743832A (en) * 2020-06-29 2020-10-09 绍兴星晨生物科技有限公司 Anti-allergy restoration chamomile compound mask and preparation method thereof
CN111789800A (en) * 2020-08-14 2020-10-20 郑州凯莉莱生物科技有限公司 Aloe composite repair factor and preparation method thereof
CN111920742A (en) * 2020-09-18 2020-11-13 微著生物科技(东营)有限责任公司 Chitosan multi-effect repair mask and preparation method thereof
CN114028310A (en) * 2021-12-09 2022-02-11 大连双迪科技股份有限公司 After-sun repair gel and preparation method thereof
CN115054559A (en) * 2022-06-27 2022-09-16 辽宁咏梅生物科技有限公司 Preparation method of skin repair solution for relieving strange marks of mask
CN115252883A (en) * 2022-03-04 2022-11-01 久益康恒基(广东)健康产业科技有限公司 Composite liquid dressing formula for rapidly repairing and sterilizing body surface injury

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110393690A (en) * 2019-08-07 2019-11-01 义乌市安彤医药科技有限公司 A kind of maintenance essence and preparation method thereof slowing down skin saccharification
CN111643716A (en) * 2020-05-26 2020-09-11 海南芬森医疗器械有限公司 Scar nursing dressing and preparation method thereof
CN111643716B (en) * 2020-05-26 2022-02-15 海南芬森医疗器械有限公司 Scar nursing dressing and preparation method thereof
CN111743832A (en) * 2020-06-29 2020-10-09 绍兴星晨生物科技有限公司 Anti-allergy restoration chamomile compound mask and preparation method thereof
CN111789800A (en) * 2020-08-14 2020-10-20 郑州凯莉莱生物科技有限公司 Aloe composite repair factor and preparation method thereof
CN111920742A (en) * 2020-09-18 2020-11-13 微著生物科技(东营)有限责任公司 Chitosan multi-effect repair mask and preparation method thereof
CN114028310A (en) * 2021-12-09 2022-02-11 大连双迪科技股份有限公司 After-sun repair gel and preparation method thereof
CN115252883A (en) * 2022-03-04 2022-11-01 久益康恒基(广东)健康产业科技有限公司 Composite liquid dressing formula for rapidly repairing and sterilizing body surface injury
CN115054559A (en) * 2022-06-27 2022-09-16 辽宁咏梅生物科技有限公司 Preparation method of skin repair solution for relieving strange marks of mask

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