CN101502481A - Spot-eliminating skin care product and preparation method thereof - Google Patents
Spot-eliminating skin care product and preparation method thereof Download PDFInfo
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- CN101502481A CN101502481A CNA2009100374511A CN200910037451A CN101502481A CN 101502481 A CN101502481 A CN 101502481A CN A2009100374511 A CNA2009100374511 A CN A2009100374511A CN 200910037451 A CN200910037451 A CN 200910037451A CN 101502481 A CN101502481 A CN 101502481A
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Abstract
The invention relates to a spot-removing skin care product and a preparation method thereof. The spot-removing skin care product comprises the following raw materials: glycerin, stearic acid, glyceryl stearate, mineral oil, tocopherol, arbutin, angelica, atractylodes rhizome and bletilla striata root extract, lavender essential oil, spermol, trolamine and a preservative. The method comprises the following steps: the raw materials are melted in a melting tank, insulated and blended evenly in a vacuum homogeneous emulsion tank, cooled and stirred to obtain the semi-finished products; the semi-finished products are inspected, discharged and filled to prepare the finished products. The spot-removing skin care product of the invention contains diverse active ingredients having the functions of whitening, spot-removing and healing and effectively inhibits tyrosinase activity, thereby comprehensively inhibiting formation of melanin, accelerating metabolism, healing damaged skin, comprehensively caring skin, improving the metabolism function of skin cell and ensuring fast spot-removing effect, good effect and no toxic side effects on human bodies.
Description
Technical field
The present invention relates to a kind of spot-eliminating skin care product and preparation method thereof.
Background technology
Mottle forms the reason complexity, ultraviolet radiation, and the endocrine disturbance, bad life habits all can cause generating too much melanin granule, forms mottle.Some speckle dispelling methods as
Chemistry strips off method or cries " changing the skin therapy " is one of speckle dispelling method that once was widely adopted.It mainly is with chemical drugss such as benzoic acid, salicylic acid, trichloroacetic acid, fruit acid, flower acid corrosion skin surface, strips off horny layer by force, reaches the speckle dispelling purpose.Though this method treatment time weak point, instant effect, cost is low, use is simple.But big to skin damage, side effect is serious, is abandoned by the people gradually.
The chemical bleaching method.Added some chemical bleaching agent mostly in the cosmetics of common those " mill cream " " refreshing water " and so on the market, as hydrogen peroxide, ammoniated mercury etc., also having some is prescriptions of forming with high concentration, potent hormone and hydroquinone.The preparation of human hydroquinone monophenyl ether is also arranged, and the hydroquinone monophenyl ether is the same with ATPA, all belongs to melanocyte toxic agent (cytotoxintomelanocyte).These melanocyte toxic agent are used for skin, can cause melanocyte death, and nonvolatil decolouring speckle takes place.In cosmetics, add these and be limited or disabled material, be undoubtedly extremely harmful.
Melanic generation is directly proportional with the activity of Tyrosinase, and the activity of Tyrosinase is high more, and the melanin of generation is just many more.Except common interior using Ve and the Vc, most Tyrosinase activities inhibitor are as playing a role in the effective ingredient adding cosmetics.Some spot-eliminating beauty treatment products on the market, though can eliminate or desalinate existing melanin, the composition of whitening wherein can not effectively be deep into the skin internal layer thereby can not effectively suppress melanic generation, mottle can occur once again after a period of time.
Summary of the invention
The object of the invention is to provide both a kind of spot-eliminating skin care product, and it can activate epiderm skin cell metabolism activity, repair impaired skin, also can effectively dispel senile plaque, freckle, cyasma and other cutaneous pigmentations.
Another purpose of the present invention is to provide the production method of this spot-eliminating skin care product.
The percentage by weight of the raw material of described spot-eliminating skin care product consists of: glycerol 9-11%, stearic acid 5-6%, glyceryl stearate 3-5%, Dormant oils 1.5-2.5%, tocopherol 1.5-2.5%, arbutin 1-2%, Radix Angelicae Sinensis (ANGELICAPOLYMORPHA SINENSIS) root extract 1-1.5%, the Rhizoma Atractylodis Macrocephalae (ATRACTYLOIDES MACROCEPHALA) root extract 1-1.5%, Herba Lysimachiae foenum-graeci quintessence oil 1-1.5%, spermol 0.8-1.2%, the Pseudobulbus Bletillae (Rhizoma Bletillae) (BLFTILLA STRIATA) root extract 1-1.5%, triethanolamine 0.7-1.0%, antiseptic 0.1-0.2%, all the other content are water.
The above-mentioned spot-eliminating skin care product of the present invention is by step preparation down;
A is with the water of described weight proportion, and glycerol adds the fusion jar, is heated to 85-95 ℃, filters to change in the vacuum emulsifying jar;
B is the stearic acid of described weight proportion, glyceryl stearate, and Dormant oils, tocopherol, spermol, antiseptic add another fusion jar, are heated to 85-95 ℃, filter to change in the described vacuum emulsifying of the A jar;
Raw material in the C vacuum emulsifying jar, 85-95 ℃ of insulated and stirred are after 15-25 minutes, cooling and stirring adds arbutin, Radix Angelicae Sinensis (ANGELICA POLYMORPHA SINENSIS) root to room temperature, the Rhizoma Atractylodis Macrocephalae (ATRACTYLOIDESMACROCEPHALA) root, the extract of the Pseudobulbus Bletillae (Rhizoma Bletillae) (BLETILLA STRIATA) root, Herba Lysimachiae foenum-graeci quintessence oil stirs, through discharging after the assay was approved, get described spot-eliminating skin care product product.
Spot-eliminating skin care product of the present invention is by from the plain material of numerous black removals, optimum organization, be picked as Radix Angelicae Sinensis (ANGELICA POLYMORPHA SINENSIS) root, the Rhizoma Atractylodis Macrocephalae (ATRACTYLOIDES MACROCEPHALA) root, the extract of the Pseudobulbus Bletillae (Rhizoma Bletillae) (BLETILLA STRIATA) root, multiple skincare substances plasmogamy system with other forms again, described plant essence spot-eliminating skin care product contains multiple whitening and speckle dispelling and repairing activity composition, effective restraint of tyrosinase activity, thereby suppress melanin forms comprehensively, and can quicken metabolism, repair impaired skin, allow the sedimentary pigment of epidermis be benefited and come off, to remove senile plaque with cutin, freckle, cyasma and other cutaneous pigmentations.The effect of each kind of plant of the present invention is (1) Radix Angelicae Sinensis (ANGELICA POLYMORPHA SINENSIS) root extract, can expand peripheral blood vessel, increase blood circulation amount etc., the restraint of tyrosinase activity, thereby can suppress melanic formation, treatment chloasma, freckle isochrome disposition dermatosis are produced effects well, have defying age and beautification function, without any side effects; (2) Rhizoma Atractylodis Macrocephalae (ATRACTYLOIDESMACROCEPHALA) root extract is warm in nature, and sweet in the mouth, hardship have the effect of slow down aging; (3) Pseudobulbus Bletillae (Rhizoma Bletillae) (BLETILLA STRIATA) root extract, the beauty treatment speckle removing, fat-reducing also can be treated dermatosiss such as acne, tinea corporis, furuncle and phyma, cicatrix; (4) Herba Lysimachiae foenum-graeci quintessence oil promotes cell regeneration, wound healing, anti-inflammation and sterilization.
The present invention is a compound preparation, and skin is carried out comprehensive maintenance, improves the metabolic function of Skin Cell, and the speckle dispelling instant effect is effective, and human body is had no side effect.
The specific embodiment
Spot-eliminating skin care product of the present invention, its raw material is formed and is acted on as follows:
Embodiment one
The described spot-eliminating skin care product of present embodiment, it is prepared from by following raw materials by weight percent:
Glycerol (Glycerol) 10%, stearic acid (Octadecanoic acid) 5.5%, glyceryl stearate (Glycerol stearate) 4%, Dormant oils (Mineral oil, claim dimethicone again, purchase great Sheng Science and Technology Ltd. in Guangdong) 2%, tocopherol (Vitamin E) 2%, arbutin (Arbutin, chemical name is right-hydroxy benzenes-β-D-glucopyanoside) 1.5%, Radix Angelicae Sinensis (ANGELICA POLYMORPHA SINENSIS) root extract 1.5%, the Rhizoma Atractylodis Macrocephalae (ATRACTYLOIDES MACROCEPHALA) root extract 1.5%, the Pseudobulbus Bletillae (Rhizoma Bletillae) (BLETILLA STRIATA) root extract 1, Herba Lysimachiae foenum-graeci quintessence oil (lavender oil) 1.2%, spermol (Cetyl alcohol) 1%, triethanolamine (Triethanolamine) 0.8%, ethyl hydroxybenzoate (Ethylparaben) 0.15%, all the other weight portions complement to 100% by water.
Radix Angelicae Sinensis (ANGELICA POLYMORPHA SINENSIS) root extract, the Rhizoma Atractylodis Macrocephalae (ATRACTYLOIDES MACROCEPHALA) root extract is purchased in Jiangxi Lignum cinnamomi camphorae Chinese crude drug specialized market, and the Pseudobulbus Bletillae (Rhizoma Bletillae) (BLETILLA STRIATA) root extract is purchased in pool, Nanjing youth Pharmaceutical Technology Co., Ltd.
Preparation process is as follows:
A is with the water of described weight proportion, and glycerol adds the fusion jar, is heated to 90 ℃, filters to change in the vacuum emulsifying jar;
B is the stearic acid of described weight proportion, glyceryl stearate, and Dormant oils, tocopherol, spermol, antiseptic add another fusion jar, are heated to 90 ℃, filter to change in the described vacuum emulsifying of the A jar;
Raw material in the C vacuum emulsifying jar, 90 ℃ of insulated and stirred are after 20 minutes, and cooling and stirring adds the arbutin of described weight proportion to room temperature, the water-soluble extract of plant, Herba Lysimachiae foenum-graeci quintessence oil stirs, and semi-finished product are through discharging after the assay was approved, and fill gets finished product.
Embodiment two
The described spot-eliminating skin care product of present embodiment, it is prepared from by following raw materials by weight percent:
Glycerol 10%, stearic acid 5.5%, glyceryl stearate 4%, Dormant oils 2%, tocopherol 2%, arbutin 1.5%, Radix Angelicae Sinensis (ANGELICA POLYMORPHA SINENSIS) root extract 1.2%, the Rhizoma Atractylodis Macrocephalae (ATRACTYLOIDES MACROCEPHALA) root extract 1.2%, the Pseudobulbus Bletillae (Rhizoma Bletillae) (BLETILLA STRIATA) root extract 1.2, Herba Lysimachiae foenum-graeci quintessence oil 1.2%, spermol 1%, triethanolamine 0.8%, ethyl hydroxybenzoate 0.15%, all the other weight portions complement to 100% by water 68.25%.
Preparation process is as follows:
A is with the water of described weight portion, and glycerol adds the fusion jar, is heated to 90 ℃, filters to change in the vacuum emulsifying jar;
B is the stearic acid of described weight portion, glyceryl stearate, and Dormant oils, tocopherol, spermol, antiseptic add another fusion jar, are heated to 90 ℃, filter to change in the described vacuum emulsifying of the A jar;
Raw material in the C vacuum emulsifying jar, 90 ℃ of insulated and stirred are after 20 minutes, and cooling and stirring adds arbutin to room temperature, the water-soluble extract of plant, and Herba Lysimachiae foenum-graeci quintessence oil stirs, and semi-finished product are through discharging after the assay was approved, and fill gets finished product.
Embodiment 3: above-mentioned spot-eliminating skin care product treatment senile plaque 600 routine observation of curative effect
One, clinical data
600 routine senile plaque patients all are the random choose patient, male's 360 examples wherein, women's 240 examples; The course of disease: 2 years to 20 years, 120 examples in 2 to 5 years, 260 examples in 5 years to 15 years, 220 examples more than 15 years.
Two, diagnostic criteria
The skin merit mainly occurs on the skin at positions such as face, forehead, arm, back, cervical region, front and as seen differs in size; the pigment patch that shape differs; what usually can form be that patch shape, its color have is filbert, coffee-like, and what have is black or brownish black.
Three, curative effect determinate standard
1, specially good effect: after senile plaque is coated the plant spot-removing skin care item, after 10 days mottle skin obviously thin out, shoal, through after 2 courses of treatment (30 days each courses of treatment) treatment after, senile plaque disappears substantially and is specially good effect.
2, produce effects: after senile plaque is coated the plant spot-removing skin care item, after 10 days mottle skin obviously thin out, shoal, after (30 days each courses of treatment) treatment after 2 courses of treatment, senile plaque has to go down more than 80% and disappears and is produce effects.
3, effective: after senile plaque is coated the plant spot-removing skin care item, after 10 days mottle skin obviously thin out, shoal, after (30 days each courses of treatment) treatment after 2 courses of treatment, senile plaque has and moves back light more than 50% and alleviate to effectively.
4, invalid: after senile plaque was coated the plant spot-removing skin care item, speckle was without any variation, and after 2 course of therapy, senile plaque does not still have thin out and the person of going down is invalid.
Four, using method
1, use the warm water cleaning pars affecta skin, hot compress is 3 to 5 minutes then, coats embodiment 1 or embodiment 2 described spot-eliminating skin care products, pats with have gentle hands then and beats pars affecta skin to rubescent heating, massages 100 times again, and then smears once.Every day, each once about two courses of treatment (60 days), can make senile plaque die away sooner or later.Take vitamin E and vitamin A as cooperation, effect is better.
Five, clinical observation on the therapeutic effect
Routine results confirm by treatment senile plaque 600: the plant spot-removing skin care item can thoroughly be treated senile plaque, smear the plant spot-removing skin care item after 10 days, all patients, and mottle all has shoaling in various degree, thin out, effective percentage 100%.After a course of treatment, the high part mottle that plays skin flattens substantially, and mottle shoals, thin out, and through the treatment of second course of treatment, senile plaque disappears substantially.Through the treatment of two courses of treatment, its senile plaque is thin out, shoal or disappear, and 419 examples at affected part in the specially good effect that senile plaque occurs, produce effects person's 156 examples, effective 25 examples.Illustrate that the plant spot-removing skin care item have the effect of dispeling senile plaque, simultaneously, visited the long-term effect of patient's 25 examples for the treatment of more than a year, there are 23 examples to keep therapeutic effect in 25 examples, do not treating the senile plaque that director makes new advances, 2 example recurrences are arranged, but color shoals obviously, illustrate that the plant spot-removing skin care item have secular effect.
Embodiment 4: above-mentioned spot-eliminating skin care product treatment chloasma 1000 routine observation of curative effect
One, clinical data
100 routine patient with chloasma all are the out-patient, male's 100 examples wherein, women's 900 examples; 30 days to 2 years 150 examples of the course of disease, 2 to 5 years 556 examples, 5 to 10 years 294 examples; Occupation: teacher's 31 examples, workman's 299 examples, government functionary's 47 examples, service man's 456 examples, shop assistant's 111 examples, student's 56 examples.
Two, diagnostic criteria
1, skin lesion mainly occurs on face, the skin and as seen differs in size, the pigment patch that shape differs, and it is filbert, coffee-like that its color is, and the black of being or sepia are arranged.
2, the pigment patch presents symmetry branch near near the eyes, and is forehead, cheekbone portion, buccal, nose and mouthful week, superficial.
3, the mutual fusion that has of mottle forms the butterfly aliform, clear border, and smooth surface does not have symptoms such as taking off clouds.
4, mottle in summer color burn after sunshine, winter is of light color.
Three, curative effect determinate standard
1, specially good effect: after chloasma faciei was coated the plant spot-removing skin care item, mottle shoaled in a week, thin out, and through (30 days per courses of treatment) after two courses of treatment, brown patch disappears substantially and is specially good effect.
2, produce effects: after facial brown patch was coated the plant spot-removing skin care item, mottle shoaled in a week, thin out, and through (30 days per courses of treatment) after two courses of treatment, 80% brown patch goes down and part disappears is produce effects.
3, effective:: after facial brown patch was coated the plant spot-removing skin care item, mottle shoaled in a week, thin out, and through (30 days per courses of treatment) after two courses of treatment, 50% brown patch goes down and alleviates to effectively.
4, invalid:: after facial brown patch was coated the plant spot-removing skin care item, through (30 days per courses of treatment) after two courses of treatment, brown patch did not have thin out or the person of going down is invalid.
Four, using method
Press the speckle dispelling routine, after washing one's face, embrocate embodiment 1 or 2 described plant spot-removing skin care item, massage is facial 5 to 8 minutes gently, and essence is fully absorbed, and every day, each used once sooner or later.
Five, clinical effectiveness is observed
The result who treats 1000 examples by clinical observation on the therapeutic effect confirms that the plant spot-removing skin care item can effectively be treated chloasma, smear a week after, except that two examples were invalid, other all patients' mottle all had shoaling in various degree, thin out, effective percentage is 99.8%.Through the treatment of two courses of treatment, two examples are invalid, specially good effect 600 examples, produce effects 377 examples, effective 23 examples.Long-term effect is observed has 201 examples that in various degree recurrence is arranged, but color is starkly lower than original color.
Embodiment 1 and 2 described spot-eliminating skin care products confirm that through on probation impaired skin is repaired in the formation that these skin care item can activate epiderm skin cell metabolism activity, slow down melanocyte, dispels the epidermis pigmentation, the desalination mottle; Can replenish skin energy, maintenance skin again, make skin shine bright white light coloured silk from inside to outside.Can effectively dispel senile plaque, freckle, cyasma and other cutaneous pigmentations.
Above-listed detailed description is at the specifying of possible embodiments of the present invention, and this embodiment is not in order to limiting claim of the present invention, and the equivalence that all the present invention of disengaging do is implemented or change, all should be contained in the claim of this case.
Claims (5)
1, a kind of spot-eliminating skin care product is characterized in that, the percentage by weight of its raw material consists of: glycerol 9-11%, stearic acid 5-6%, glyceryl stearate 3-5%, Dormant oils 1.5-2.5%, tocopherol 1.5-2.5%, arbutin 1-2%, angelica root extract 1-1.5%, Rhizoma Atractylodis Macrocephalae root extract 1-1.5%, Herba Lysimachiae foenum-graeci quintessence oil 1-1.5%, spermol 0.8-1.2%, Pseudobulbus Bletillae (Rhizoma Bletillae) root extract 1-1.5%, triethanolamine 0.7-1.0%, antiseptic 0.1-0.2%, all the other content are water.
2, spot-eliminating skin care product according to claim 1 is characterized in that, the percentage by weight of its raw material consists of: glycerol 10%, stearic acid 5.5%, glyceryl stearate 4%, Dormant oils 2%, tocopherol 2%, arbutin 1.5%, angelica root extract 1.2%, Rhizoma Atractylodis Macrocephalae root extract 1.2%, Herba Lysimachiae foenum-graeci quintessence oil 1.2%, spermol 1%, Pseudobulbus Bletillae (Rhizoma Bletillae) root extract 1.2%, triethanolamine 0.8%, antiseptic 0.15%, all the other content are water.
3, spot-eliminating skin care product according to claim 1 and 2 is characterized in that, described antiseptic is an ethyl hydroxybenzoate.
4, the described spot-eliminating skin care product of a kind of preparation claim 1 is characterized in that, may further comprise the steps;
A is with the water of described weight proportion, and glycerol adds the fusion jar, is heated to 85-95 ℃, filters to change in the vacuum emulsifying jar;
B is the stearic acid of described weight proportion, glyceryl stearate, and Dormant oils, tocopherol, spermol, antiseptic add another fusion jar, are heated to 85-95 ℃, filter to change in the described vacuum emulsifying of the A jar;
Raw material in the C vacuum emulsifying jar, 85-95 ℃ of insulated and stirred are after 15-25 minutes, cooling and stirring adds the arbutin of described weight proportion, angelica root to room temperature, Rhizoma Atractylodis Macrocephalae root, the extract of Pseudobulbus Bletillae (Rhizoma Bletillae) root, Herba Lysimachiae foenum-graeci quintessence oil stirs, through discharging after the assay was approved, fill gets described spot-eliminating skin care product.
5. preparation method according to claim 4 is characterized in that, described antiseptic is an ethyl hydroxybenzoate.
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| CNA2009100374511A CN101502481A (en) | 2009-02-27 | 2009-02-27 | Spot-eliminating skin care product and preparation method thereof |
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| CNA2009100374511A CN101502481A (en) | 2009-02-27 | 2009-02-27 | Spot-eliminating skin care product and preparation method thereof |
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| CN102178638A (en) * | 2010-11-29 | 2011-09-14 | 吴克 | Bodybuilding cream |
| WO2011129765A1 (en) * | 2010-04-16 | 2011-10-20 | Davos Life Science Pte. Ltd. | Synergistic interaction of at least one vitamin e component and tyrosinase inhibitors for dermatological applications |
| CN103202792A (en) * | 2013-03-01 | 2013-07-17 | 郑州市嘉蓓丽贸易有限公司 | Skin care lotion containing wax gourd, honey and egg yolk |
| CN103690427A (en) * | 2013-12-12 | 2014-04-02 | 上海应用技术学院 | Application of lemon essential oil serving as tyrosinase inhibitor to freckle-removing cosmetics |
| CN104644529A (en) * | 2015-03-18 | 2015-05-27 | 谢妮妮 | Freckle-removing herbal composition, freckle-removing herbal extract and freckle-removing facial cleanser and preparation method thereof |
| CN106137937A (en) * | 2015-03-23 | 2016-11-23 | 天津药物研究院有限公司 | A kind of pharmaceutical composition for skin-whitening and preparation method thereof |
| CN106176463A (en) * | 2016-08-24 | 2016-12-07 | 刘艺鹏 | Spot removing skin softening emulsion containing the Fructus Kochiae |
| CN107375154A (en) * | 2017-09-15 | 2017-11-24 | 广州赛莱拉干细胞科技股份有限公司 | A kind of nti-freckle white composition and preparation method thereof only |
| CN107595756A (en) * | 2017-11-01 | 2018-01-19 | 蒋冰冰 | A kind of whitening is dispelled black compound |
| CN107898725A (en) * | 2017-12-19 | 2018-04-13 | 广东德新科技孵化器有限公司 | Non-stimulated Essence of a kind of nti-freckle and preparation method thereof |
| CN108743504A (en) * | 2018-07-26 | 2018-11-06 | 湖南慕她生物科技发展有限公司 | A kind of plant acid whitening freckle-removing cream and its production technology |
| CN110269830A (en) * | 2019-07-24 | 2019-09-24 | 杭州兰茜化妆品有限公司 | A kind of Bletilla glucomannan repair latex and its preparation and application |
| CN110433122A (en) * | 2019-09-11 | 2019-11-12 | 吉林省强参生物技术有限公司 | A kind of composition and its application in the skin care item for preparing light speckles, beautification and white |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2011129765A1 (en) * | 2010-04-16 | 2011-10-20 | Davos Life Science Pte. Ltd. | Synergistic interaction of at least one vitamin e component and tyrosinase inhibitors for dermatological applications |
| CN102178638A (en) * | 2010-11-29 | 2011-09-14 | 吴克 | Bodybuilding cream |
| CN103202792A (en) * | 2013-03-01 | 2013-07-17 | 郑州市嘉蓓丽贸易有限公司 | Skin care lotion containing wax gourd, honey and egg yolk |
| CN103202792B (en) * | 2013-03-01 | 2014-08-13 | 郑州市嘉蓓丽生物科技有限公司 | Skin care lotion containing wax gourd, honey and egg yolk |
| CN103690427A (en) * | 2013-12-12 | 2014-04-02 | 上海应用技术学院 | Application of lemon essential oil serving as tyrosinase inhibitor to freckle-removing cosmetics |
| CN104644529A (en) * | 2015-03-18 | 2015-05-27 | 谢妮妮 | Freckle-removing herbal composition, freckle-removing herbal extract and freckle-removing facial cleanser and preparation method thereof |
| CN106137937A (en) * | 2015-03-23 | 2016-11-23 | 天津药物研究院有限公司 | A kind of pharmaceutical composition for skin-whitening and preparation method thereof |
| CN106176463A (en) * | 2016-08-24 | 2016-12-07 | 刘艺鹏 | Spot removing skin softening emulsion containing the Fructus Kochiae |
| CN107375154A (en) * | 2017-09-15 | 2017-11-24 | 广州赛莱拉干细胞科技股份有限公司 | A kind of nti-freckle white composition and preparation method thereof only |
| CN107595756A (en) * | 2017-11-01 | 2018-01-19 | 蒋冰冰 | A kind of whitening is dispelled black compound |
| CN107898725A (en) * | 2017-12-19 | 2018-04-13 | 广东德新科技孵化器有限公司 | Non-stimulated Essence of a kind of nti-freckle and preparation method thereof |
| CN108743504A (en) * | 2018-07-26 | 2018-11-06 | 湖南慕她生物科技发展有限公司 | A kind of plant acid whitening freckle-removing cream and its production technology |
| CN110269830A (en) * | 2019-07-24 | 2019-09-24 | 杭州兰茜化妆品有限公司 | A kind of Bletilla glucomannan repair latex and its preparation and application |
| CN110433122A (en) * | 2019-09-11 | 2019-11-12 | 吉林省强参生物技术有限公司 | A kind of composition and its application in the skin care item for preparing light speckles, beautification and white |
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