CN107753357A - Toning lotion containing stem cell secretion factors - Google Patents
Toning lotion containing stem cell secretion factors Download PDFInfo
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- CN107753357A CN107753357A CN201711299098.5A CN201711299098A CN107753357A CN 107753357 A CN107753357 A CN 107753357A CN 201711299098 A CN201711299098 A CN 201711299098A CN 107753357 A CN107753357 A CN 107753357A
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- Prior art keywords
- toner
- skin
- parts
- stem cell
- tetrapeptide
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- 210000000130 stem cell Anatomy 0.000 title claims abstract description 28
- 230000028327 secretion Effects 0.000 title claims abstract description 27
- 239000006210 lotion Substances 0.000 title abstract 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 20
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims abstract description 13
- 229920002674 hyaluronan Polymers 0.000 claims abstract description 12
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 claims abstract description 12
- 239000008367 deionised water Substances 0.000 claims abstract description 9
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 9
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims abstract description 7
- 229960003160 hyaluronic acid Drugs 0.000 claims abstract description 7
- 229960003080 taurine Drugs 0.000 claims abstract description 6
- 125000000913 palmityl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 19
- 239000007788 liquid Substances 0.000 claims description 16
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 claims description 13
- 235000005340 Asparagus officinalis Nutrition 0.000 claims description 11
- 239000000284 extract Substances 0.000 claims description 10
- 241000196324 Embryophyta Species 0.000 claims description 9
- 238000000605 extraction Methods 0.000 claims description 9
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 8
- QTEWJFPLRGWOOU-IHRRRGAJSA-N (2s)-2-[[(2s)-2-[[(2s)-2-(3-aminopropanoylamino)-3-(1h-imidazol-5-yl)propanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1h-imidazol-5-yl)propanoic acid Chemical compound C([C@H](NC(=O)CCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC=1NC=NC=1)C(O)=O)C1=CN=CN1 QTEWJFPLRGWOOU-IHRRRGAJSA-N 0.000 claims description 7
- 230000002421 anti-septic effect Effects 0.000 claims description 7
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 6
- -1 palmityl tetrapeptide -7 Chemical compound 0.000 claims description 6
- 235000017166 Bambusa arundinacea Nutrition 0.000 claims description 5
- 235000017491 Bambusa tulda Nutrition 0.000 claims description 5
- 235000001287 Guettarda speciosa Nutrition 0.000 claims description 5
- 235000015334 Phyllostachys viridis Nutrition 0.000 claims description 5
- 239000011425 bamboo Substances 0.000 claims description 5
- 244000061520 Angelica archangelica Species 0.000 claims description 4
- 229930003427 Vitamin E Natural products 0.000 claims description 4
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 4
- 229940046009 vitamin E Drugs 0.000 claims description 4
- 235000019165 vitamin E Nutrition 0.000 claims description 4
- 239000011709 vitamin E Substances 0.000 claims description 4
- CHHHXKFHOYLYRE-UHFFFAOYSA-M 2,4-Hexadienoic acid, potassium salt (1:1), (2E,4E)- Chemical compound [K+].CC=CC=CC([O-])=O CHHHXKFHOYLYRE-UHFFFAOYSA-M 0.000 claims description 3
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims description 3
- UWJJYHHHVWZFEP-UHFFFAOYSA-N pentane-1,1-diol Chemical compound CCCCC(O)O UWJJYHHHVWZFEP-UHFFFAOYSA-N 0.000 claims description 3
- 229940069338 potassium sorbate Drugs 0.000 claims description 3
- 235000010241 potassium sorbate Nutrition 0.000 claims description 3
- 239000004302 potassium sorbate Substances 0.000 claims description 3
- 125000002252 acyl group Chemical group 0.000 claims description 2
- 244000003416 Asparagus officinalis Species 0.000 claims 3
- 244000082204 Phyllostachys viridis Species 0.000 claims 1
- 230000037303 wrinkles Effects 0.000 abstract description 20
- 230000001815 facial effect Effects 0.000 abstract description 9
- 230000008439 repair process Effects 0.000 abstract description 8
- 230000032683 aging Effects 0.000 abstract description 6
- 239000013589 supplement Substances 0.000 abstract description 5
- 230000036039 immunity Effects 0.000 abstract description 4
- 208000028990 Skin injury Diseases 0.000 abstract description 3
- ROTFCACGLKOUGI-JYJNAYRXSA-N (2s)-2-[[(2s)-2-[[(2s)-2-(3-acetamidopropanoylamino)-3-(1h-imidazol-5-yl)propanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1h-imidazol-5-yl)propanoic acid Chemical compound C([C@H](NC(=O)CCNC(=O)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC=1NC=NC=1)C(O)=O)C1=CN=CN1 ROTFCACGLKOUGI-JYJNAYRXSA-N 0.000 abstract description 2
- 210000003491 skin Anatomy 0.000 abstract 2
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 abstract 2
- IHRKJQSLKLYWBQ-QKDODKLFSA-N (2s)-2-[[(2s)-1-[(2s)-5-amino-2-[[2-(hexadecanoylamino)acetyl]amino]-5-oxopentanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid Chemical compound CCCCCCCCCCCCCCCC(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(O)=O IHRKJQSLKLYWBQ-QKDODKLFSA-N 0.000 abstract 1
- LODWEXDBRZBADB-XEVVZDEMSA-N (2s)-6-amino-2-[[(2s)-2-[[(2s)-6-amino-2-(hexadecanoylamino)hexanoyl]amino]-3-methylbutanoyl]amino]hexanoic acid Chemical compound CCCCCCCCCCCCCCCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(O)=O LODWEXDBRZBADB-XEVVZDEMSA-N 0.000 abstract 1
- 241001116389 Aloe Species 0.000 abstract 1
- 235000011399 aloe vera Nutrition 0.000 abstract 1
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 abstract 1
- 229940094946 palmitoyl tetrapeptide-7 Drugs 0.000 abstract 1
- 229940094912 palmitoyl tripeptide-5 Drugs 0.000 abstract 1
- 210000004927 skin cell Anatomy 0.000 abstract 1
- 229940032094 squalane Drugs 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 20
- 241000234427 Asparagus Species 0.000 description 8
- 102000008186 Collagen Human genes 0.000 description 6
- 108010035532 Collagen Proteins 0.000 description 6
- 229920001436 collagen Polymers 0.000 description 6
- 230000006378 damage Effects 0.000 description 6
- 230000000474 nursing effect Effects 0.000 description 6
- 230000003712 anti-aging effect Effects 0.000 description 5
- 238000004140 cleaning Methods 0.000 description 5
- 239000002537 cosmetic Substances 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 241001330002 Bambuseae Species 0.000 description 4
- 235000016709 nutrition Nutrition 0.000 description 4
- 108090000765 processed proteins & peptides Proteins 0.000 description 4
- 230000003716 rejuvenation Effects 0.000 description 4
- 230000037331 wrinkle reduction Effects 0.000 description 4
- 239000002253 acid Substances 0.000 description 3
- 150000001413 amino acids Chemical class 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 230000002708 enhancing effect Effects 0.000 description 3
- 230000035764 nutrition Effects 0.000 description 3
- 230000001151 other effect Effects 0.000 description 3
- 238000011084 recovery Methods 0.000 description 3
- 229930003231 vitamin Natural products 0.000 description 3
- 235000013343 vitamin Nutrition 0.000 description 3
- 239000011782 vitamin Substances 0.000 description 3
- 229940088594 vitamin Drugs 0.000 description 3
- 150000003722 vitamin derivatives Chemical class 0.000 description 3
- 230000002087 whitening effect Effects 0.000 description 3
- 206010020649 Hyperkeratosis Diseases 0.000 description 2
- 208000001126 Keratosis Diseases 0.000 description 2
- 208000003351 Melanosis Diseases 0.000 description 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 2
- 239000005864 Sulphur Substances 0.000 description 2
- 230000003796 beauty Effects 0.000 description 2
- 235000013399 edible fruits Nutrition 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 238000002649 immunization Methods 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000003020 moisturizing effect Effects 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 230000037380 skin damage Effects 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 238000003786 synthesis reaction Methods 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 239000011573 trace mineral Substances 0.000 description 2
- 235000013619 trace mineral Nutrition 0.000 description 2
- 241000125175 Angelica Species 0.000 description 1
- 206010013786 Dry skin Diseases 0.000 description 1
- 102000016942 Elastin Human genes 0.000 description 1
- 108010014258 Elastin Proteins 0.000 description 1
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 description 1
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 description 1
- 201000001376 Familial Combined Hyperlipidemia Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 102000015696 Interleukins Human genes 0.000 description 1
- 108010063738 Interleukins Proteins 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 235000021314 Palmitic acid Nutrition 0.000 description 1
- 102000035195 Peptidases Human genes 0.000 description 1
- 108091005804 Peptidases Proteins 0.000 description 1
- 244000273256 Phragmites communis Species 0.000 description 1
- 235000014676 Phragmites communis Nutrition 0.000 description 1
- 206010063493 Premature ageing Diseases 0.000 description 1
- 208000032038 Premature aging Diseases 0.000 description 1
- 239000004365 Protease Substances 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- PYKYMHQGRFAEBM-UHFFFAOYSA-N anthraquinone Chemical class CCC(=O)c1c(O)c2C(=O)C3C(C=CC=C3O)C(=O)c2cc1CC(=O)OC PYKYMHQGRFAEBM-UHFFFAOYSA-N 0.000 description 1
- 150000004056 anthraquinones Chemical class 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 229940064004 antiseptic throat preparations Drugs 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000000975 bioactive effect Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 230000007969 cellular immunity Effects 0.000 description 1
- 230000019522 cellular metabolic process Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 210000003764 chromatophore Anatomy 0.000 description 1
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- 238000007796 conventional method Methods 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
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- 230000001934 delay Effects 0.000 description 1
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- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 230000037336 dry skin Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 229920002549 elastin Polymers 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000001339 epidermal cell Anatomy 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 229930003944 flavone Natural products 0.000 description 1
- 150000002213 flavones Chemical class 0.000 description 1
- 235000011949 flavones Nutrition 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 230000013595 glycosylation Effects 0.000 description 1
- 238000006206 glycosylation reaction Methods 0.000 description 1
- 239000003102 growth factor Substances 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
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- 238000001727 in vivo Methods 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 230000000116 mitigating effect Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 description 1
- IPCSVZSSVZVIGE-UHFFFAOYSA-N n-hexadecanoic acid Natural products CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 239000012466 permeate Substances 0.000 description 1
- 150000007965 phenolic acids Chemical class 0.000 description 1
- 239000000419 plant extract Substances 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000037394 skin elasticity Effects 0.000 description 1
- 230000005808 skin problem Effects 0.000 description 1
- 230000036558 skin tension Effects 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
- A61K8/466—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfonic acid derivatives; Salts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a toning lotion containing stem cell secretion factors, which comprises palmitoyl tetrapeptide-7, palmitoyl tripeptide-5, acetyl tetrapeptide-5, stem cell secretion factors, aloe juice, hyaluronic acid, taurine, squalane and deionized water. The toning lotion disclosed by the invention can clean the skin, quickly supplement the moisture of the skin, repair skin injury, remove wrinkles, improve the immunity of facial skin cells and delay aging.
Description
Technical field
The present invention relates to cosmetic technical field, more particularly, to a kind of toner containing stem cell secretion factor.
Background technology
With the increasingly improvement of economy, living standard, skin nursing has turned into a part for people's daily life.Skin
Basic nursing mainly includes three clean skin, skin-active, skin care steps, is referred to as " daily nursing trilogy ".Toner is fast because of energy
Speed supplements the moisture of keratoderma and turns into the step of key one " taken over from the past and set a new course for the future " in trilogy.Toner is that a kind of liquid is made up
Product, the surface of skin is applied to, can be used for cleaning skin, keep the health of skin, be that the daily beauty and skin care of people must can not
Few articles for use.At the same time, the modern life and working environment easily trigger skin premature aging, cause skin quality to decline, go out
The aging phenomena such as existing low and deep, loose, wrinkle.Therefore, pursuit of the people to whitening, nti-freckle, anti-ageing and other effects class cosmetic product
Increasingly strengthening.
Kept the skin wet rapidly however, toner in the market is only capable of providing, there is certain moist function.Therefore
In order to obtain other such as whitening, nti-freckle, anti-ageing and other effects, consumer is in daily nursing, after using toner, it is also necessary to apply
Smear the various cosmetics with other effects, such as essence, emulsion, face cream.This cause daily cosmetic it is time-consuming compared with
Long, nursing procedure is various, and if nursing procedure mistake, also easily causes some effects not realize；Moreover, because needing to buy
The cosmetics of various difference in functionalitys, cost is very high, spends high.
Therefore, research and develop it is a with multi-functional toner with good market prospects.
The content of the invention
In view of this, it is an object of the invention to provide a kind of toner containing stem cell secretion factor, the toner to exist
While cleaning skin, rapid supplement skin moisture, moreover it is possible to repair skin damage, wrinkle reduction, improve skin of face cell
Immunity, anti-aging.
To achieve the above object, the invention provides a kind of toner containing stem cell secretion factor, including palmityl four
Peptide -7, palmityl tripeptides -5, acetyl group tetrapeptide -5, stem cell secretion factor, asparagus juice, hyaluronic acid, taurine, saualane and
Deionized water.
Preferably, based on 100 parts by weight, the toner includes following components：2-6 part palmityl tetrapeptides -7,3-5 part palm fibre
Palmitic acid acyl tripeptides -5,2-4 part acetyl group tetrapeptide -5,0.5-1.5 part stem cell secretion factor, 8-10 part asparagus juices, 0.5-3 parts are transparent
Matter acid, 0.5-1.5 part taurines, 0.5-1.2 parts saualane and deionized water surplus.
Preferably, based on 100 parts by weight, the toner includes following components：3-5 part palmityl tetrapeptides -7,3.5-4.5
Part palmityl tripeptides -5,2.5-3.5 part acetyl group tetrapeptide -5,0.8-1.2 part stem cell secretion factor, 8.5-9.5 part asparagus juices,
1.5-2 part hyaluronic acids, 0.8-1.2 part taurines, 0.8-1.0 parts and deionized water surplus.
Preferably, based on 100 parts by weight, the toner also includes 4-6 part plant extraction liquids.
Preferably, the plant extraction liquid is the extract solution of bamboo leaves selected from angelica extract, one kind in lucidum extracting liquid or
It is a variety of.
Preferably, based on 100 parts by weight, the toner also includes 0.5-1 part vitamin Es.
Preferably, in terms of 100 parts by weight, the toner also includes the antiseptic of 1.5-2.5 parts.
Preferably, the antiseptic is the one or more in potassium sorbate, pungent glycol, pentanediol.
According to the toner provided by the invention containing stem cell secretion factor, wherein contain asparagus juice, hyaluronic acid, ox sulphur
Acid, saualane, when cleaning skin, nutrition and the moisture of skin can be supplemented rapidly, recover the elasticity of skin, meanwhile, the change
Also containing palmityl tetrapeptide -7, palmityl tripeptides -5 and acetyl group tetrapeptide -5 in adornment water, it can repair the damage of face skin,
Facial wrinkles are dispelled, while coordinate stem cell secretion factor, while skin injury is repaired, additionally it is possible to improve the immune of skin
Power, enhancing skin, so as to support the generation of wrinkle, are really achieved the effect of skin rejuvenation to the tolerance and resistance of external environment
Fruit, delay the aging of face skin.
The additional aspect and advantage of the present invention will be set forth in part in the description, and will partly become from the following description
Obtain substantially, or recognized by the practice of the present invention.
Embodiment
In order to better illustrate the present invention, with reference to specific embodiment, the present invention will be further described.It is appreciated that
, these specific embodiments are exemplary, are only used for explaining the present invention, and are not considered as limiting the invention.
Embodiments of the invention provide a kind of toner containing stem cell secretion factor, and the toner includes palmityl four
Peptide -7, palmityl tripeptides -5, acetyl group tetrapeptide -5, stem cell secretion factor, asparagus juice, hyaluronic acid, taurine, saualane and
Deionized water.
In the formula of toner provided by the invention, asparagus juice rich in polysaccharide, amino acid and vitamin etc. it is water-soluble into
Point, the water absorbing properties of keratoderma can be remarkably reinforced, is a kind of natural moisture preserving agent and skin-nourishing agent, skin can be supplemented rapidly
The moisture and nutritional ingredient lost in skin, promote the recovery of collagen function, prevent the formation of wrinkle of skin.Hyaluronic acid energy
Enough skin is helped to draw substantial amounts of moisture, can be with moment deep moisturizing, increase skin elasticity and tension force, and can aid in extensive
The normal oil-water balance of multiple skin, improve drying machine relaxation skin.There is taurine extraordinary skin-active to act on, and can strengthen skin
Skin can provide the lasting moisture-retaining capacity of skin to the transdermal absorption factors of various nutrients；Taurine also has and improved simultaneously
Skin immunity, resist the effect of external environment is attacked.Saualane has the effect of skin care, and has preferable parent to skin
And property, can speed up other in formula, perhaps composition permeates into skin.Therefore, toner provided by the invention is in daily shield
During reason, cleaning skin, skin level, and permanent moisturizing can be supplemented rapidly, increase the elasticity and degree of compacting of skin.
Meanwhile also contain palmityl tetrapeptide -7, palmityl tripeptides -5, acetyl group in the formula of toner provided by the invention
Tetrapeptide -5, stem cell secretion factor.
Wherein, palmityl tetrapeptide -7 be it is a kind of victory peptide is synthesized by four Amino acid profiles, can delay and suppress excessive
The generation of interleukin, damage, have significant anti-so as to suppress some unnecessary inappropriate inflammatory reactions and glycosylation
Edema, smooth away wrinkles, the effect of anti-inflammatory, tolerance of the skin to external environment can be strengthened.Meanwhile it can also stimulate skin
The synthesis and development of collagen (I type, II type, IV type) and elastin laminin, reach and compact and plentiful skin in skin skin corium
Effect.Palmityl tripeptides -5 can promote the synthesis of collagen (I type, II type familial combined hyperlipidemia) by increasing stroma cell activity
With the generation of extracellular matrix protein, strengthen connective tissue, promote cytoactive, while protect collagen not by matrix metal
Proteases for decomposing, both act synergistically, and effective wrinkle reduction, improve skin quality, allow skin to seem more aobvious young and high resilience.
Collagen is cross-linked with each other used in saccharification, its be produce wrinkle the reason for one of, acetyl tetrapeptide -5 can suppress saccharification,
So as to reduce being cross-linked with each other for collagen, the effect of reaching mitigation and resist wrinkle, the elasticity and smoothness of skin are improved.
Stem cell secretion factor contains the extremely strong growth factor of a large amount of physiological actions, can activate in vivo in a dormant state
Various stem cells, supplement various fresh cells for body, substitute aging and impaired cell, and then repair skin damage
Wound, wrinkle reduction, makes skin reach the state of overall rejuvenation.Meanwhile stem cell secretion factor is also containing being improved immunity
The factor, leucocyte can be stimulated to regenerate, improve cutaneous immunisation power, and then improve tolerance and resistance of the skin to adverse circumstances
Power, it is significantly reduced the generation of skin problem.
Therefore, toner provided by the invention can repair the damage of face skin, dispel facial wrinkles, repair skin
While damage, additionally it is possible to improve the immunity of skin, enhancing skin wrinkles to the tolerance and resistance of external environment so as to support
The generation of line, the effect of skin rejuvenation is really achieved, delays the aging of face skin
It is understood that palmityl tetrapeptide -7 in the present invention, palmityl tripeptides -5, acetyl group tetrapeptide -5, stem cell
Secretion factor can be prepared using method commonly used in the art, and this is not described in detail the present invention.
In some embodiments of the invention, based on 100 parts by weight, the toner includes following components：2-6 part palms
Acyl tetrapeptide -7,3-5 part palmityl tripeptides -5,2-4 part acetyl group tetrapeptide -5,0.5-1.5 part stem cell secretion factor, 8-10 part reeds
Luxuriant growth juice, 0.5-3 part hyaluronic acids, 0.5-1.5 part taurines, 0.5-1.2 parts saualane and deionized water surplus.Preferably, exist
In other embodiments of the present invention, based on 100 parts by weight, the toner includes following components：3-5 part palmityls tetrapeptide-
7,3.5-4.5 part palmityl tripeptides -5,2.5-3.5 part acetyl group tetrapeptide -5,0.8-1.2 part stem cell secretion factors, 8.5-9.5
Part asparagus juice, 1.5-2 part hyaluronic acids, 0.8-1.2 part taurines, 0.8-1.0 parts and deionized water surplus.
In some embodiments of the invention, the toner can also contain plant extraction liquid, and plant extraction liquid contains
Nutrient needed for various skins, skin-nourishing can be supplemented.In some embodiments of the invention, it is described based on 100 parts by weight
Toner also includes 4-6 part plant extraction liquids.
It is understood that the present invention is not particularly limited to the species of plant extraction liquid, it can be various this areas
Conventional plant extraction liquid, as long as skin-nourishing can be supplemented.In some embodiments of the invention, the plant extract
Liquid is the one or more in angelica extract, extract solution of bamboo leaves, lucidum extracting liquid.
Angelica extract has oxidation resistant effect, can supplement body nutrition and trace element, improves skin color, increases
Add whitening skin, transparent effect.It is more containing substantial amounts of flavones, phenolic acid, anthraquinone analog compound, bioactivity in extract solution of bamboo leaves
The trace element such as peptide, extraordinary amino acid and manganese, zinc, has good skin-softening beauty effect, can recover skin younger state, promotees
Enter skin smooth exquisiteness.There are abundant bioactive ingredients in lucidum extracting liquid, it has the effect of obvious anti-aging,
And cutaneous immunisation ability can be adjusted, regulation skin metabolism balance, free radical in skin is eliminated, keeps skin activity.
It can also be appreciated that the material such as the angelica extract in the present invention, extract solution of bamboo leaves, lucidum extracting liquid
To be prepared using method commonly used in the art, this is not described in detail the present invention.
In some embodiments of the invention, vitamin E can also be added with toner provided by the invention.Vitamin
E has softening skin cuticula, accelerates epidermal cell metabolism, desalination tegumentary chromatophore and reduction lipid peroxy reaction
Obvious effect.And vitamin E additionally aids the skin that makes to relax becomes smooth, pale, speedy recovery to health state.In the present invention
Some embodiments in, based on 100 parts by weight, the toner includes 0.5-1 part vitamin Es.
In some embodiments of the invention, in terms of 100 parts by weight, can also contain in toner provided by the invention
The antiseptic of 0.5-2.5 parts.It is understood that the present invention is not particularly limited to the species of antiseptic, can be this area
Conventional various antiseptics, for example, the one or more in potassium sorbate, pungent glycol, pentanediol etc..
According to the toner provided by the invention containing stem cell secretion factor, the conventional method in this area can be used to prepare
And obtain, the application is no longer repeated this.
According to the toner provided by the invention containing stem cell secretion factor, wherein contain asparagus juice, hyaluronic acid, ox sulphur
Acid, saualane, when cleaning skin, nutrition and the moisture of skin can be supplemented rapidly, recover the elasticity of skin, meanwhile, the change
Also containing palmityl tetrapeptide -7, palmityl tripeptides -5 and acetyl group tetrapeptide -5 in adornment water, it can repair the damage of face skin,
Facial wrinkles are dispelled, while coordinate stem cell secretion factor, while skin injury is repaired, additionally it is possible to improve the immune of skin
Power, enhancing skin, so as to support the generation of wrinkle, are really achieved the effect of skin rejuvenation to the tolerance and resistance of external environment
Fruit, delay the aging of face skin.
The invention is further illustrated by the following examples, but the embodiment is merely to illustrate the present invention rather than limitation
The present invention.
Formula as described in table 1 prepares toner, then carries out using effect test and carries out effect statistics.
Table 1
The method of using effect test：
60 female volunteers are selected, age distribution is 35-50 year, is randomly divided into six groups, every group 10 of A, B, C, D, E, F
People.Wherein A groups every morning is used every morning using the toner once prepared by formula 1 in the above-mentioned table 1 of the present invention, B groups
The toners once prepared by formula 2 in the above-mentioned table 1 of the present invention, use every morning of C groups are once formulated in above-mentioned table 1 of the invention
3 toners prepared, D groups every morning use the toners of the preparations of formula 4 in once above-mentioned table 1 of the invention, E groups every mornings
Using the toner that in once above-mentioned table 1 of the invention prepared by formula 5, F group every mornings use once conventional toner, difference
Face skin wrinkle situation is detected after being used continuously 8 weeks.
Table 2
| A groups | After 8 weeks, skin water profit gloss, facial wrinkles are reduced. |
| B groups | After 8 weeks, skin water profit gloss, facial wrinkles are reduced. |
| C groups | After 8 weeks, skin water profit gloss, facial wrinkles are reduced. |
| D groups | After 8 weeks, skin water profit gloss, facial wrinkles are reduced. |
| E groups | After 8 weeks, skin water profit gloss, facial wrinkles are reduced. |
| F groups | After 8 weeks, dry skin is low and deep, and wrinkle increase is obvious. |
Can be seen that the toner provided by the invention containing stem cell secretion factor from the using effect in upper table can mend
Skin moisture is filled, recovery water moistens the skin that compacts, while can also repair the damage of face skin, wrinkle reduction, resists the production of wrinkle
It is raw, so as to real anti-aging.
Although an embodiment of the present invention has been shown and described, it will be understood by those skilled in the art that：Not
In the case of departing from the principle and objective of the present invention a variety of change, modification, replacement and modification can be carried out to these embodiments, this
The scope of invention is limited by claim and its equivalent.
Claims (8)
1. a kind of toner containing stem cell secretion factor, it is characterised in that the toner includes palmityl tetrapeptide -7, palm
Acyl tripeptides -5, acetyl group tetrapeptide -5, stem cell secretion factor, asparagus juice, hyaluronic acid, taurine, saualane and deionized water.
2. toner as claimed in claim 1, it is characterised in that based on 100 parts by weight, the toner is included with the following group
Point：2-6 part palmityl tetrapeptide -7,3-5 part palmityl tripeptides -5,2-4 part acetyl group tetrapeptide -5,0.5-1.5 part stem cell secretions
The factor, 8-10 part asparagus juices, 0.5-3 part hyaluronic acids, 0.5-1.5 part taurines, more than 0.5-1.2 parts saualane and deionized water
Amount.
3. toner as claimed in claim 2, it is characterised in that based on 100 parts by weight, the toner is included with the following group
Point：3-5 part palmityl tetrapeptide -7,3.5-4.5 part palmityl tripeptides -5,2.5-3.5 part acetyl group tetrapeptide -5,0.8-1.2 parts are done
Cell-secretion factor, 8.5-9.5 part asparagus juices, 1.5-2 part hyaluronic acids, 0.8-1.2 part taurines, 0.8-1.0 parts and go from
Sub- water surplus.
4. toner as claimed in claim 2, it is characterised in that based on 100 parts by weight, the toner also includes 4-6 parts
Plant extraction liquid.
5. toner as claimed in claim 4, it is characterised in that the plant extraction liquid is selected from angelica extract, the leaf of bamboo
Extract solution, the one or more in lucidum extracting liquid.
6. toner as claimed in claim 2, it is characterised in that based on 100 parts by weight, the toner also includes 0.5-1
Part vitamin E.
7. toner as claimed in claim 2, it is characterised in that in terms of 100 parts by weight, the toner also includes 1.5-
2.5 parts of antiseptic.
8. toner as claimed in claim 7, it is characterised in that the antiseptic is in potassium sorbate, pungent glycol, pentanediol
One or more.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201711299098.5A CN107753357A (en) | 2017-12-08 | 2017-12-08 | Toning lotion containing stem cell secretion factors |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201711299098.5A CN107753357A (en) | 2017-12-08 | 2017-12-08 | Toning lotion containing stem cell secretion factors |
Publications (1)
| Publication Number | Publication Date |
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| CN107753357A true CN107753357A (en) | 2018-03-06 |
Family
ID=61277820
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| Application Number | Title | Priority Date | Filing Date |
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| CN201711299098.5A Withdrawn CN107753357A (en) | 2017-12-08 | 2017-12-08 | Toning lotion containing stem cell secretion factors |
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| CN (1) | CN107753357A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109172859A (en) * | 2018-09-06 | 2019-01-11 | 上海长海医院 | Human stem cell source excretion bluk recombination exogenous hyaluronic acid is preparing the application in skin wound defect repair drug or material |
| CN110075035A (en) * | 2019-06-10 | 2019-08-02 | 上海龙禧投资有限公司 | A kind of hair restorer of the part containing hair stroma cell activator |
| CN110664989A (en) * | 2018-07-18 | 2020-01-10 | 广州市尚昇生物科技有限公司 | Striae gravidarum removing composition containing polypeptide and preparation method and application thereof |
| CN112638355A (en) * | 2018-08-29 | 2021-04-09 | 株式会社资生堂 | Cosmetic and cleaning product |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102068391A (en) * | 2010-12-30 | 2011-05-25 | 广州赛莱拉化妆品科技有限公司 | Application of human steam cell growth factors in cosmetics |
| CN104000744A (en) * | 2014-06-12 | 2014-08-27 | 金玲 | Hairdressing liquid capable of improving metabolism of skin and delaying senescence and production method of hairdressing liquid capable of improving metabolism of skin and delaying senescence |
-
2017
- 2017-12-08 CN CN201711299098.5A patent/CN107753357A/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102068391A (en) * | 2010-12-30 | 2011-05-25 | 广州赛莱拉化妆品科技有限公司 | Application of human steam cell growth factors in cosmetics |
| CN104000744A (en) * | 2014-06-12 | 2014-08-27 | 金玲 | Hairdressing liquid capable of improving metabolism of skin and delaying senescence and production method of hairdressing liquid capable of improving metabolism of skin and delaying senescence |
Non-Patent Citations (1)
| Title |
|---|
| 钟星等: "胜肽在化妆品中的应用和最新进展", 《日用化学品科学》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110664989A (en) * | 2018-07-18 | 2020-01-10 | 广州市尚昇生物科技有限公司 | Striae gravidarum removing composition containing polypeptide and preparation method and application thereof |
| CN112638355A (en) * | 2018-08-29 | 2021-04-09 | 株式会社资生堂 | Cosmetic and cleaning product |
| CN109172859A (en) * | 2018-09-06 | 2019-01-11 | 上海长海医院 | Human stem cell source excretion bluk recombination exogenous hyaluronic acid is preparing the application in skin wound defect repair drug or material |
| CN110075035A (en) * | 2019-06-10 | 2019-08-02 | 上海龙禧投资有限公司 | A kind of hair restorer of the part containing hair stroma cell activator |
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Application publication date: 20180306 |