CN106614628A - Bactericidal composition - Google Patents
Bactericidal composition Download PDFInfo
- Publication number
- CN106614628A CN106614628A CN201611119503.6A CN201611119503A CN106614628A CN 106614628 A CN106614628 A CN 106614628A CN 201611119503 A CN201611119503 A CN 201611119503A CN 106614628 A CN106614628 A CN 106614628A
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- China
- Prior art keywords
- flutianil
- dimethirimol
- ethirimol
- bupirimate
- bactericidal composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 159000000003 magnesium salts Chemical class 0.000 description 1
- 229920000609 methyl cellulose Polymers 0.000 description 1
- BSDQITJYKQHXQR-UHFFFAOYSA-N methyl prop-2-eneperoxoate Chemical class COOC(=O)C=C BSDQITJYKQHXQR-UHFFFAOYSA-N 0.000 description 1
- 239000001923 methylcellulose Substances 0.000 description 1
- 238000003801 milling Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 229910052901 montmorillonite Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 235000021017 pears Nutrition 0.000 description 1
- 239000005011 phenolic resin Substances 0.000 description 1
- 230000008635 plant growth Effects 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229920000136 polysorbate Polymers 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 229940068968 polysorbate 80 Drugs 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 229940088417 precipitated calcium carbonate Drugs 0.000 description 1
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 description 1
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 239000011265 semifinished product Substances 0.000 description 1
- 239000000779 smoke Substances 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 150000003548 thiazolidines Chemical class 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 235000020234 walnut Nutrition 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/74—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,3
- A01N43/78—1,3-Thiazoles; Hydrogenated 1,3-thiazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a bactericidal composition, whose effective component is composed of A and B, wherein the A is flutianil, the B is any one of ethirimol, bupirimate, and dimethirimol, and the mass ratio of A to B is 1:50 to 50:1. The synergistic effect of the composition is prominent. The control effect of the bactericidal composition is good. The bactericidal composition is suitable for controlling various diseases of vegetables and fruits, especially powdery mildew.
Description
Technical field
The present invention relates to a kind of bactericidal composition, more particularly to a kind of Bactericidal composite with flutianil as main component
The application of thing and its preventing and treating corps diseases, belongs to technical field of pesticide.
Background technology
Powdery mildew is the plant disease caused by the Erysiphaceae (Erysiphacesae) in fungi.For example：By standing grain white powder
The Cereal powdery mildew that bacterium (Ery-siphe graminis) causes；By Siberian cocklebur monofilament shell (Sphaerotheca fuliginea)
The powdery mildew of the various plants such as the melon, beans, the crudefiber crop that cause；The Portugal caused by grape snag shell (Uncinula necator)
Grape powdery mildew；Mulberry, pears, persimmon, walnut, chestnut, lichee, papaya caused by hazel ball pin shell (Phyllactinia corylea) etc.
The powdery mildew of more than 80 kinds of trees；The powdery mildew of the Flowers of Rosa caused by rose monofilament shell (Sphaerotheca pannosa)
Deng.
In the preventing and treating of powdery mildew, the sterilizations such as benzimidazole, triazole type, methoxy acrylate class are relied primarily at present
Agent.Because Long-Time Service has generated the different degrees of resistance to the action of a drug, prevention effect is reduced these medicaments.In addition, triazole type medicament
There is inhibitory action to plant growth when dosage is big, easily cause poisoning.
Flutianil be thiazolidines bactericide, molecular formula：C19H14F4N20S2, molecular weight 426.5.The medicament is by suppression
The mycelial growth of pathogen processed and take effect.Flutianil is in extremely low concentration (10mg/L) to diseases such as the powdery mildews of gourd, fruit and vegetable
The tall and erect effect of evil tool.
, used as a kind of new type bactericide, current production and use cost is higher, and individually makes for a long time for flutianil
With also there is very big resistance risk.
The content of the invention
It is an object of the invention to provide a kind of synergistic effect is substantially, low cost good to powdery mildew prevention effect, resistance risk
Low bactericidal composition.
It is a further object of the present invention to provide the application of the bactericidal composition.
Inventor has been surprisingly found that flutianil and ethirimol or second by substantial amounts of indoor biometricses and field control effectiveness test
Phonetic sulfocarbolate or dimethirimol after mixture, have significant synergistic effect to diseases such as powdery mildews in certain proportion.
The mechanism of action of the ethirimol, bupirimate and dimethirimol is adenosine deaminase inhibitors.
The ethirimol
English name：ethirimol
Chemical name：5- butyl -2- ethylamino -4- hydroxyl -6- methylpyrimidines
Molecular formula：C11H19N3O
It is mainly used in preventing and treating cereal crop powdery mildew, can also prevents and treats ground family crop powdery mildew.
The bupirimate English name：bupirimate
Chemical name：5- butyl -2- ethylamino -6- methylpyrimidine -4- base dimethylamino sulphonic acid esters
Molecular formula：C13H24N4O3S
It is mainly used in preventing and treating various powdery mildews, such as apple, grape, cucumber, strawberry, rose, beet powdery mildew.
The dimethirimol：English name：dimethirimol
Chemical name：5- normal-butyl -2- dimethylamino -6- methylpyrimidine 4- alcohol
Molecular formula：C11H19N3O
It is mainly used in preventing and treating melon, tobacco, tomato, the powdery mildew of ornamental plant.
Ethirimol, bupirimate, dimethirimol are bactericide well known in the art, can pass through various commercial channel
Obtain.
To overcome the deficiencies in the prior art, such solution is the technical scheme is that：A kind of bactericidal composition, contains
Effective constituents A and B, A are flutianil, and B is any one in ethirimol, bupirimate and dimethirimol, A
It is the ︰ 1 of 1 ︰ 50～50 with the mass ratio of B, preferred mass ratio is 1:30～30:1.
Said composition can be processed into any formulation for agriculturally allowing, and preferable formulation has missible oil, microemulsion, water and milk
Agent, suspending agent, suspension emulsion, wettable powder or water dispersible granules.
In the bactericidal composition of the present invention, effective constituents A is 5%～85% with the mass accumulation percentage composition of B, and remaining is
Auxiliary agent and filler or diluent.
The formulation of above-mentioned bactericidal composition also contributes to drug effect including auxiliary agent in addition to including effective constituents A and B with other
The material of performance.Missible oil includes organic solvent, cosolvent and emulsifying agent；Microemulsion includes organic solvent, emulsifying agent and water；Water and milk
Agent includes organic solvent, dispersant, emulsifying agent and water；Suspending agent includes water, dispersant, thickener, antifreezing agent and wetting agent；Can
WP includes wetting agent, dispersant and filler；Water dispersible granules include dispersant, disintegrant, filler and wetting agent.More than
All it is to commonly use in pesticidal preparations or allow the various composition for using, is not particularly limited, concrete composition and consumption will according to formula
Ask and determined by simple experiment.For example：
Organic solvent may be selected isopropanol, dimethylbenzene, N,N-dimethylformamide, ring ethyl ketone, toluene, dimethyl sulfoxide (DMSO),
Methyl alcohol, ethanol, trimethyl cyclic ethylene ketone, NOP, 1-METHYLPYRROLIDONE, propyl alcohol, butanol, ethylene glycol, diethyl
One or more in glycol, EGME, butyl ether, ethyl acetate, vegetable oil.
Cosolvent may be selected the one kind or many in 1-METHYLPYRROLIDONE, dimethylformamide, ethanol, the third ethanol, acetone
Kind.
Dispersant may be selected sodium lignin sulfonate, calcium lignosulfonate, pull open powder, calcium dodecyl benzene sulfonate, polycarboxylic acids
Salt, alkyl benzene sulfonate calcium salt, APES, aliphatic amine polyoxyethylene ether, polyoxyethylene carboxylate, glycerin fatty
One or more in acid ester polyoxyethylene ether.
Emulsifying agent may be selected agricultural emulsifier NO.600 (phenyl phenol polyoxyethyl ether), agriculture breast 1601, and (phenethyl phenol polyoxyethanyl gathers
Propenyl ether), agriculture breast 500 (alkyl benzene calcium sulfonate), OP series phosphate (thermally coupled distillation columns), No. 600
Phosphate (phenyl phenol polyoxyethanyl ether phosphate), styrene polyoxyethylene rice ammonium sulfate, alkyl biphenyl ether disulfonic acid magnesium salts,
Triethanolamine salt, agriculture breast 400 (benzyl xylenol polyoxyethyl ether), Nongru-700 number (alkyl phenolic resin polyoxyethyl ether),
Agriculture breast 36 (phenethyl phenol formaldehyde resin polyoxyethyl ether), agriculture breast 1600 (phenethyl phenol polyoxyethanyl polypropylene-base ether),
Ethylene oxide-propylene oxide block copolymer, OP series (NPE), No. 33 (alkylaryl polyoxies third of agriculture breast
Alkene APEO), agriculture breast 34 (alkylaryl polyoxyethylene poly-oxygen propylene aether), Span series (sorbitol anhydride monostearate
Ester), TWEEN Series (sorbitan fatty acid ester APEO), AEO series (fat alcohol alcohol APEO) in one kind
Or it is various.
Antifreezing agent may be selected one or more in glycerine, urea, ethylene glycol, propane diols.
Wetting agent may be selected methyl naphthalene sulfonate formaldehyde condensate, lauryl sodium sulfate, Negel, alkylbenzene
One or more in sulfoacid calcium, tea seed cake, spaonin powder, silkworm excrement, spaonin powder, bay alcohol radical sodium sulphate, washing powder, pull open powder.
Disintegrant may be selected the one kind in ammonium sulfate, urea, bentonite, aluminium chloride, citric acid, succinic acid, sodium acid carbonate
Or it is various.
Thickener may be selected in xanthans, hydroxymethyl cellulose, methylcellulose, Magnesiumaluminumsilicate, polyvinyl alcohol it is a kind of or
It is various.
Filler may be selected White Carbon black, ridge soil, precipitated calcium carbonate, talcum, montmorillonite or convex-concave rod stone, float stone, brickbat, Hai Pao
One or more in stone or bentonite and non-adsorbent calcium soil or sand.
Product described in the invention can be provided in finished product preparation form, i.e., each material is blended in composition, combination
The composition of thing can also be provided with unit dose form, directly be mixed in proportion in bucket or tank using front, needed for being then diluted to
Concentration.
The bactericidal composition of the present invention is particularly suited for preventing and treating powdery mildew.The composition of the present invention can be by common method
Apply, such as cast, injection, spraying, dusting, distribution or smoke, its amount of application changes with weather condition or crop condition.
Compared with prior art, its advantage is the present invention：1st, substantially, preventive effect is notable compared with single dose for composition synergistic effect
Improve；2nd, after drug effect is improved, the effective ingredient consumption in field declines, and reduces production and use cost, reduces residues of pesticides
And environmental pollution；3rd, composition is made up of the active ingredient of different mechanism of action, and action site increases, and is conducive to overcoming and delays
The drug-fast generation of germ.
Specific embodiment
The pesticide active ingredient of different types of structure is compounded, is to solve cost in agricultural chemicals single dose application process at present
And a kind of effective means the problems such as resistance.After the pesticide active ingredient mixing of different types of structure, three kinds of works are typically exhibited
With type, i.e. summation action, synergistic effect and antagonism, but it is specially which kind of effect, it is impossible to predict, only by a large amount of examinations
Test and just can know that.Compound synergic is filled a prescription well, can improve actual prevention effect, reduces the usage amount of agricultural chemicals, contributes to delaying
The generation of resistance, is the important means of scientific prevention and cure pest and disease damage.
The present composition has obvious synergistic function, and not exclusively two kinds pharmacy effects to Powdery Mildew etc.
Simple addition, this can from following toxicity test experiment result in be clear that.
Biologicall test example 1：Composition is tested the Toxicity Determination of cucurbits powdery mildew bacterium
Subjects are cucumber powdery mildew's pathogen (Sphaerotheca fuliginea).
Test method：Reference《People's Republic of China (PRC) agricultural industry criteria NY/T 1156.11-2008》.Choose growth potential
Consistent potted plant two panels leaf period cucumber seedling, is sprayed with Potter spray towers under 50PSI pressure, per basin 5mL.Each medicament sets
Put 5 concentration gradients.Inoculum density is carried out after 24h for 3 × 105The cucumber powdery mildew's pathogen conidial suspension of individual spore/mL.
To spray the cucumber seedling of equivalent clear water as blank.Cucumber seedling is put in greenhouse after inoculation is cultivated.After 10d, according to cucumber
The morbidity grade scale investigation disease index of powdery mildew, and calculate prevention effect.
Powdery mildew of cucumber severity Scaling standard：
0 grade：Blade disease-free spot；
1 grade：Lesion area accounts for the area of whole blade below 5%；
3 grades：Lesion area accounts for the 6%～10% of the area of whole blade；
5 grades：Lesion area accounts for the 11%～25% of whole blade area；
7 grades：Lesion area accounts for the 25%～50% of whole blade area；
9 grades：Lesion area accounts for more than the 50% of whole blade area.
The expected effect (i.e. theoretical prevention effect, %) of mixture of active principles determined using Colby formula and with observation
To effect compare：
Colby formula：E=X+Y-X*Y/100
E：When active components A concentration is a in composition, compositions contemplated effect when active component B concentrations are b
Power.
X：Effect when active components A dosage is a.
Y：Effect when active component B dosages are b.
When the actual prevention effect observed exceedes expected preventive effect, explanation mixture has synergistic effect.
Toxicity test result is referring to table 1 to table 3.
The flutianil of table 1 compounds the pot experiment measurement result to cucumber powdery mildew's pathogen with ethirimol
The flutianil of table 2 compounds the pot experiment measurement result to cucumber powdery mildew's pathogen with bupirimate
The flutianil of table 3 compounds the pot experiment measurement result to cucumber powdery mildew's pathogen with dimethirimol
Result of the test shows, flutianil and ethirimol or bupirimate or dimethirimol are in certain proportion scope
Interior compounding prevents and treats powdery mildew of cucumber, with synergistic effect.
In order that the objects, technical solutions and advantages of the present invention become more apparent, present invention preparation reality in detail below
Example is illustrated, but the present invention is limited to absolutely not these examples.Described below is only the present invention preferably embodiment, only to solve
The present invention is released, therefore the restriction to the scope of the claims of the present invention can not be interpreted as.It should be pointed out that all essences in the present invention
Any modification, equivalent and improvement made within god and principle etc., should be included within the scope of the present invention.Cause
This, the protection domain of patent of the present invention should be defined by claims.
Missible oil embodiment
Pesticide active ingredient, emulsifying agent, solvent are mixed in proportion, is mixed in modulation kettle, until completely dissolved,
Remaining solvent is slowly added into again, uniform oil phase is obtained after being sufficiently stirred for, make missible oil product.
Embodiment 1,51%flutianil 〃 ethirimol missible oil
Flutianil 50%, ethirimol 1%, agriculture breast No. 500 2% (emulsifying agent), dimethylbenzene (solvent) are supplemented to
100%.
Embodiment 2,31%flutianil 〃 ethirimol missible oil
Flutianil 30%, ethirimol 1%, POLYSORBATE 80 3% (emulsifying agent), toluene (solvent) are supplemented to 100%.It is real
Apply example 3,51%flutianil 〃 bupirimate missible oil
Flutianil 50%, bupirimate 1%, agricultural emulsifier NO.600 2% (emulsifying agent), dimethylbenzene (solvent) are supplemented
To 100%.
Embodiment 4,31%flutianil 〃 bupirimate missible oil
Flutianil 30%, bupirimate 1%, agriculture breast No. 1,600 3% (emulsifying agent), toluene (solvent) are supplemented to
100%.
Embodiment 5,51%flutianil 〃 dimethirimol missible oil
Flutianil 50%, dimethirimol 1%, agriculture breast No. 500 2% (emulsifying agent), dimethylbenzene (solvent) are supplemented to
100%.
Embodiment 6,31%flutianil 〃 dimethirimol missible oil
Flutianil 30%, dimethirimol 1%, agriculture breast No. 1,601 3% (emulsifying agent), toluene (solvent) are supplemented to
100%.
Microemulsion, aqueous emulsion embodiment
By each group distribution ratio, active component is dissolved in solvent and cosolvent, adds surfactant, be well mixed system
Obtain oil phase.Water-soluble component and water are mixed to prepare into water phase, then oil phase are added in water phase or water is added in oil phase, side edged
Stirring, is obtained microemulsion or aqueous emulsion.
Embodiment 7,5%flutianil 〃 ethirimol microemulsions
Flutianil 2.5%, ethirimol 2.5%, cyclohexanol (solvent) 10%, agriculture breast No. 500 8% (emulsifying agent), agricultures
Breast No. 600 5% (emulsifying agent), agriculture breast No. 1,600 5% (emulsifying agent), sldium lauryl sulfate 2% (wetting agent), ethylene glycol 5% are (anti-
Freeze agent), water be supplemented to 100%
Embodiment 8,11%flutianil 〃 ethirimol emulsion in water
Flutiani l0%, ethirimol 1%, DMF (solvent) 5%, toluene 8% (solvent), glycerine (antifreezing agent) 5%, benzene
Ethyl phenol polyethenoxy ether (emulsifying agent) 10%, calcium dodecyl benzene sulfonate (wetting agent) 5%, water is supplemented to 100%
Embodiment 9,5%flutianil 〃 bupirimate microemulsions
Flutianil 2.5%, bupirimate 2.5%, toluene 8% (solvent), agriculture breast No. 500 8% (emulsifying agent),
Agricultural emulsifier NO.600 5% (emulsifying agent), agriculture breast No. 1,600 5% (emulsifying agent), sldium lauryl sulfate 2% (wetting agent), ethylene glycol 5%
(antifreezing agent), water are supplemented to 100%
Embodiment 10,11%flutianil 〃 bupirimate aqueous emulsions
Flutianil 10%, bupirimate 1%, DMF (solvent) 5%, cyclohexanol (solvent) 10%, glycerine are (anti-
Freeze agent) 5%, phenethyl phenol polyethenoxy ether (emulsifying agent) 10%, calcium dodecyl benzene sulfonate (wetting agent) 5%, water be supplemented to
100%
Embodiment 11,5%flutianil 〃 dimethirimol microemulsions
Flutianil 2.5%, dimethirimol 2.5%, toluene 8% (solvent), agriculture breast No. 500 8% (emulsifying agent), agriculture breasts
No. 600 5% (emulsifying agent), agriculture breast No. 1,600 5% (emulsifying agent), sldium lauryl sulfate 2% (wetting agent), ethylene glycol 5% are (antifreeze
Agent), water be supplemented to 100%
Embodiment 12,11%flutianil 〃 dimethirimol aqueous emulsions
Flutianil0%, dimethirimol 1%, DMF (solvent) 5%, cyclohexanol (solvent) 10%, glycerine (antifreezing agent)
5%th, phenethyl phenol polyethenoxy ether (emulsifying agent) 10%, calcium dodecyl benzene sulfonate (wetting agent) 5%, water is supplemented to 100%
Suspension emulsion embodiment
The each components such as active ingredient, dispersant, wetting agent, defoamer, thickener and water is equal in the ratio mixing of formula
It is even, semi-finished product are obtained Jing after sand milling or high speed shear, the filtration that is mixed with water is mended after analysis and obtains final product suspending agent.
First solid active ingredient is obtained into stable dense suspension.Using high-shear mixer, by liquid active ingredient breast
Liquid phase is added in suspension, and suspension emulsion is obtained.
Embodiment 13,31%flutianil 〃 ethirimol suspending agents
Flutianil 1%, ethirimol 30%, sodium lignin sulfonate (dispersant) 5%, APES 8%
(wetting agent), propane diols 2% (antifreezing agent), xanthans 1% (thickener), organosilicon 2% (defoamer), water are supplemented to 100%
Embodiment 14,51%flutianil 〃 ethirimol suspending agents
Flutianil 1%, ethirimol 50%, calcium lignosulfonate (dispersant) 5%, APES 8%
(wetting agent), propane diols 2% (antifreezing agent), xanthans 1% (thickener), organosilicon 2% (defoamer), water are supplemented to 100%
Embodiment 15,31%flutianil 〃 bupirimate suspending agents
Flutianil 1%, bupirimate 30%, calcium lignosulfonate (dispersant) 6%, alkylphenol-polyethenoxy
Ether 6% (wetting agent), propane diols 2% (antifreezing agent), xanthans 1% (thickener), organosilicon 2% (defoamer), water are supplemented to
100%
Embodiment 16,51%flutianil 〃 bupirimate suspension emulsions
Flutianil 1%, bupirimate 50%, sodium lignin sulfonate (dispersant) 5%, alkylphenol-polyethenoxy
Ether 6% (wetting agent), propane diols 2% (antifreezing agent), xanthans 1% (thickener), organosilicon 2% (defoamer), water are supplemented to
100%
Embodiment 17,31%flutianil 〃 dimethirimol suspending agents
Flutianil 1%, dimethirimol 30%, calcium lignosulfonate (dispersant) 8%, APES
8% (wetting agent), propane diols 2% (antifreezing agent), xanthans 1% (thickener), organosilicon 2% (defoamer), water are supplemented to
100%
Embodiment 18,51%flutianil 〃 dimethirimol suspending agents
Flutianil 1%, dimethirimol 50%, sodium lignin sulfonate (dispersant) 7%, APES
8% (wetting agent), propane diols 2% (antifreezing agent), xanthans 1% (thickener), organosilicon 2% (defoamer), water are supplemented to
100%
Water dispersible granules embodiment
Pesticide activity component, auxiliary agent and filler are mixed in proportion, Jing air-flow crushings, then add the water of 15-20%, Jing to pinch
Close, granulate, being dried, screening is obtained water dispersible granules product.Capital equipment：Mixer, airslide disintegrating mill, kneader, extruding are made
Grain machine, drying equipment (drying room or fluid bed).
Embodiment 19,85%flutianil 〃 ethirimol water dispersible granules
Flutianil50%, ethirimol 35%, neopelex 2% (wetting agent), sodium lignin sulfonate 4%
(dispersant), ammonium sulfate 2% (disintegrant), kaolin (filler) to 100%
Embodiment 20,85%flutianil 〃 bupirimate water dispersible granules
Flutianil50%, bupirimate 35%, neopelex 2% (wetting agent), lignin sulfonic acid
Sodium 5% (dispersant), ammonium sulfate 3% (disintegrant), White Carbon black (filler) to 100%
Embodiment 21,85%flutianil 〃 dimethirimol water dispersible granules
Flutianil45%, dimethirimol 40%, neopelex 2% (wetting agent), sodium lignin sulfonate
6% (dispersant), ammonium sulfate 2% (disintegrant), talcum powder (filler) to 100%
Wettable powder embodiment
Pesticide activity component, auxiliary agent, filler are mixed in proportion Jing after air-flow crushing and remixes prepared wettable powder.It is main
Want equipment：Mixer, airslide disintegrating mill.
Embodiment 22,50%flutianil 〃 ethirimol wettable powders
Flutianil15%, ethirimol 35%, bay alcohol radical sodium sulphate 4% (wetting agent), mersolates 7% (point
Powder), white carbon 8% (filler), kaolin (filler) to 100%
Embodiment 23,11%flutianil 〃 ethirimol wettable powders
Flutianil 1%, ethirimol 10%, bay alcohol radical sodium sulphate 4% (wetting agent), mersolates 7% (point
Powder), white carbon 8% (filler), talcum powder (filler) to 100%
Embodiment 24,50%flutianil 〃 bupirimate wettable powders
Flutianil10%, bupirimate 40%, bay alcohol radical sodium sulphate 4% (wetting agent), mersolates
7% (dispersant), white carbon 8% (filler), diatomite (filler) to 100%
Embodiment 25,11%flutianil 〃 bupirimate wettable powders
Flutianil 1%, bupirimate 10%, bay alcohol radical sodium sulphate 4% (wetting agent), mersolates
7% (dispersant), white carbon 8% (filler), kaolin (filler) to 100%
Embodiment 26,50%flutianil 〃 dimethirimol wettable powders
Flutianil5%, dimethirimol 45%, bay alcohol radical sodium sulphate 4% (wetting agent), mersolates 7%
(dispersant), white carbon 8% (filler), diatomite (filler) to 100%,
Embodiment 27,11%flutianil 〃 dimethirimol wettable powders
Flutianil 1%, dimethirimol 10%, bay alcohol radical sodium sulphate 4% (wetting agent), mersolates 7%
(dispersant), white carbon 8% (filler), talcum powder (filler) to 100%,
Field information example 1：Flutianil compounds the field control effectiveness test to powdery mildew of cucumber with ethirimol
Test site Guangdong Zengcheng.Test medicine and consumption are shown in Table 4, often process 4 cells and repeat, each plot area 20
Square metre.First time dispenser is carried out in disease early period of origination, even spraying is sprayed onto till blade drips, and with clear water sky is processed as
White control.Second medicine is applied after 7 days.The incidence of 7 days investigation powderys mildew of cucumber before first time medicine and after second medicine.Often
Using 5 points of samplings, per is investigated two plants to cell, and per plant is investigated all blades, with the percentage that lesion area accounts for whole leaf area
To be classified record.Calculate each process disease index and prevention effect.
Grade scale：
0 grade：Disease-free spot；
1 grade：Lesion area accounts for less than the 5% of whole leaf area；
3 grades：Lesion area accounts for the 6%-15% of whole leaf area；
5 grades：Lesion area accounts for the 16%-25% of whole leaf area；
7 grades：Lesion area accounts for the 26%-50% of whole leaf area；
9 grades：Lesion area accounts for more than the 50% of whole leaf area.
Drug effect computational methods：
As can be seen from Table 4：Flutianil, ethirimol single dose are respectively 76.5% and to the preventive effect of powdery mildew of cucumber
74.8%, and embodiment of the present invention bactericidal composition is significantly increased in preventive effect, minimum preventive effect is 85.8%, up to
90.3%.The result of field test fully shows have significantly to powdery mildew of cucumber after flutianil and ethirimol compounding
Synergistic function, in the case where effective ingredient consumption is compared with single dose reduction, prevention effect is greatly improved.Therefore, of the present invention group
The beneficial effect that compound has reduces cost, delaying drug resistance, reduces spraying times and residues of pesticides.
The flutianil of table 4 compounds the field test results to powdery mildew of cucumber with ethirimol
Field information example 2：Flutianil compounds the field control effectiveness test to uncinula necator with ethirimol
Test site Yunan border areas.Test medicine and consumption are shown in Table 5, often process 4 cells and repeat, each plot area 20
Square metre.First time dispenser is carried out in disease early period of origination, even spraying is sprayed onto till blade drips, and with clear water sky is processed as
White control.Second medicine is applied after 7 days.The incidence of 7 days investigation uncinula necators before first time medicine and after second medicine.Often
Using 5 points of samplings, per is investigated two plants to cell, and per plant is investigated all blades, with the percentage that lesion area accounts for whole leaf area
To be classified record.Calculate each process disease index and prevention effect.
Grade scale and drug effect computational methods are with Field information example 1.
As can be seen from Table 5：Flutianil, ethirimol single dose are respectively 79.5% and to the preventive effect of uncinula necator
74.9%, and embodiment of the present invention bactericidal composition is significantly increased in preventive effect, minimum preventive effect is 87.6%, up to
92.8%.The result of field test fully shows have significantly to uncinula necator after flutianil and ethirimol compounding
Synergistic function, in the case where effective ingredient consumption is compared with single dose reduction, prevention effect is significantly improved.Therefore, of the present invention group
The beneficial effect that compound has reduces cost, delaying drug resistance, reduces spraying times and residues of pesticides.
The flutianil of table 5 compounds the field test results to uncinula necator with ethirimol
Field information example 3：Flutianil compounds the field control effectiveness test to powdery mildew of cucumber with bupirimate
Test site Zhanjiang.Test medicine and consumption are shown in Table 6, often process 4 cells and repeat, each plot area 20
Square metre.First time dispenser is carried out in disease early period of origination, even spraying is sprayed onto till blade drips, and with clear water sky is processed as
White control.Second medicine is applied after 7 days.The incidence of 7 days investigation powderys mildew of cucumber before first time medicine and after second medicine.Often
Using 5 points of samplings, per is investigated two plants to cell, and per plant is investigated all blades, with the percentage that lesion area accounts for whole leaf area
To be classified record.Calculate each process disease index and prevention effect.
Grade scale and drug effect computational methods are with Field information example 1.
As can be seen from Table 6：Flutianil, bupirimate single dose are respectively to the preventive effect of powdery mildew of cucumber
79.2% and 75.6%, and embodiment of the present invention bactericidal composition is significantly increased in preventive effect, minimum preventive effect is 88.4%,
It has been up to 91.5%.The result of field test fully shows that flutianil is white to cucumber after compounding with bupirimate
Powder disease has significant synergistic function, and in the case where effective ingredient consumption is compared with single dose reduction, prevention effect is greatly improved.
Therefore, the beneficial effect that the present composition has reduces cost, delaying drug resistance, reduces spraying times and residues of pesticides.
The flutianil of table 6 compounds the field test results to powdery mildew of cucumber with bupirimate
Field information example 4：Flutianil compounds the field control effectiveness test to uncinula necator with bupirimate
Test site Hunan Shaoyang.Test medicine and consumption are shown in Table 7, often process 4 cells and repeat, each plot area 20
Square metre.First time dispenser is carried out in disease early period of origination, even spraying is sprayed onto till blade drips, and with clear water sky is processed as
White control.Second medicine is applied after 7 days.The incidence of 7 days investigation uncinula necators before first time medicine and after second medicine.Often
Using 5 points of samplings, per is investigated two plants to cell, and per plant is investigated all blades, with the percentage that lesion area accounts for whole leaf area
To be classified record.Calculate each process disease index and prevention effect.
Grade scale and drug effect computational methods are with Field information example 1.
As can be seen from Table 7：Flutianil, bupirimate single dose are respectively to the preventive effect of uncinula necator
74.1% and 71.9%, and embodiment of the present invention bactericidal composition is significantly increased in preventive effect, minimum preventive effect is 82.7%,
It has been up to 86.9%.The result of field test fully shows that flutianil is white to grape after compounding with bupirimate
Powder disease has significant synergistic function, and in the case where effective ingredient consumption is compared with single dose reduction, prevention effect is significantly improved.
Therefore, the beneficial effect that the present composition has reduces cost, delaying drug resistance, reduces spraying times and residues of pesticides.
The flutianil of table 7 compounds the field test results to uncinula necator with bupirimate
Field information example 5：Flutianil compounds the field control effectiveness test to powdery mildew of cucumber with dimethirimol
Test site Zhaoqing Guangdong.Test medicine and consumption are shown in Table 8, often process 4 cells and repeat, each plot area 20
Square metre.First time dispenser is carried out in disease early period of origination, even spraying is sprayed onto till blade drips, and with clear water sky is processed as
White control.Second medicine is applied after 7 days.The incidence of 7 days investigation powderys mildew of cucumber before first time medicine and after second medicine.Often
Using 5 points of samplings, per is investigated two plants to cell, and per plant is investigated all blades, with the percentage that lesion area accounts for whole leaf area
To be classified record.Calculate each process disease index and prevention effect.
Grade scale and drug effect computational methods are with Field information example 1.
As can be seen from Table 8：Flutianil, dimethirimol single dose are respectively 76.3% and to the preventive effect of powdery mildew of cucumber
73.9%, and embodiment of the present invention bactericidal composition is significantly increased in preventive effect, minimum preventive effect is 85.4%, up to
89.3%.The result of field test fully shows have significantly to powdery mildew of cucumber after flutianil and dimethirimol compounding
Synergistic function, effective ingredient consumption compared with single dose reduction in the case of, prevention effect is greatly improved.Therefore, the present invention
The beneficial effect that composition has reduces cost, delaying drug resistance, reduces spraying times and residues of pesticides.
The flutianil of table 8 compounds the field test results to powdery mildew of cucumber with dimethirimol
Field information example 6：Flutianil compounds the field control effectiveness test to uncinula necator with dimethirimol
Test site Zhejiang Dongyang.Test medicine and consumption are shown in Table 9, often process 4 cells and repeat, each plot area 20
Square metre.First time dispenser is carried out in disease early period of origination, even spraying is sprayed onto till blade drips, and with clear water sky is processed as
White control.Second medicine is applied after 7 days.The incidence of 7 days investigation uncinula necators before first time medicine and after second medicine.Often
Using 5 points of samplings, per is investigated two plants to cell, and per plant is investigated all blades, with the percentage that lesion area accounts for whole leaf area
To be classified record.Calculate each process disease index and prevention effect.
Grade scale and drug effect computational methods are with Field information example 1.
As can be seen from Table 9：Flutianil, dimethirimol single dose are respectively 79.9% and to the preventive effect of uncinula necator
77.4%, and embodiment of the present invention bactericidal composition is significantly increased in preventive effect, minimum preventive effect is 87.8%, up to
92.1%.The result of field test fully shows have significantly to uncinula necator after flutianil and dimethirimol compounding
Synergistic function, effective ingredient consumption compared with single dose reduction in the case of, prevention effect is significantly improved.Therefore, the present invention
The beneficial effect that composition has reduces cost, delaying drug resistance, reduces spraying times and residues of pesticides.
The flutianil of table 9 compounds the field test results to uncinula necator with dimethirimol
Claims (5)
1. a kind of bactericidal composition, it is characterised in that：Be flutianil containing effective constituents A and B, A, B be selected from ethirimol,
Any one in bupirimate and dimethirimol, the mass ratio of A and B is the ︰ 1 of 1 ︰ 50～50.
2. bactericidal composition according to claim 1, it is characterised in that：The mass ratio of effective constituents A and B be 1 ︰ 30～
30 ︰ 1.
3. bactericidal composition according to claim 1 and 2, it is characterised in that：The mass accumulation of active ingredient in composition
Percentage composition is 5%～85%.
4. bactericidal composition according to claim 3, it is characterised in that：Formulation is missible oil, microemulsion, aqueous emulsion, suspension
Agent, suspension emulsion, wettable powder or water dispersible granules.
5. application of the bactericidal composition described in claim 1 in preventing and treating gourd, fruit and vegetable powdery mildew.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109077056A (en) * | 2018-10-10 | 2018-12-25 | 山东省联合农药工业有限公司 | A kind of efficient bactericidal composite |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010029030A2 (en) * | 2008-09-12 | 2010-03-18 | Basf Se | Fungicidal mixtures |
| CN101984818A (en) * | 2010-08-06 | 2011-03-16 | 东莞市瑞德丰生物科技有限公司 | Germicide composition |
| WO2011056463A2 (en) * | 2009-11-04 | 2011-05-12 | E. I. Du Pont De Nemours And Company | Fungicidal mixtures |
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2016
- 2016-12-08 CN CN201611119503.6A patent/CN106614628A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010029030A2 (en) * | 2008-09-12 | 2010-03-18 | Basf Se | Fungicidal mixtures |
| WO2011056463A2 (en) * | 2009-11-04 | 2011-05-12 | E. I. Du Pont De Nemours And Company | Fungicidal mixtures |
| CN101984818A (en) * | 2010-08-06 | 2011-03-16 | 东莞市瑞德丰生物科技有限公司 | Germicide composition |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109077056A (en) * | 2018-10-10 | 2018-12-25 | 山东省联合农药工业有限公司 | A kind of efficient bactericidal composite |
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