CN103181390B - Pesticide composition containing diaryl ketone compound - Google Patents
Pesticide composition containing diaryl ketone compound Download PDFInfo
- Publication number
- CN103181390B CN103181390B CN201110461812.2A CN201110461812A CN103181390B CN 103181390 B CN103181390 B CN 103181390B CN 201110461812 A CN201110461812 A CN 201110461812A CN 103181390 B CN103181390 B CN 103181390B
- Authority
- CN
- China
- Prior art keywords
- pyriofenone
- powdery mildew
- dimethirimol
- bupirimate
- cucumber
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000000203 mixture Substances 0.000 title claims abstract description 59
- -1 diaryl ketone compound Chemical class 0.000 title abstract description 30
- 239000000575 pesticide Substances 0.000 title abstract description 14
- 241000221785 Erysiphales Species 0.000 claims abstract description 43
- CJHXCRMKMMBYJQ-UHFFFAOYSA-N dimethirimol Chemical compound CCCCC1=C(C)NC(N(C)C)=NC1=O CJHXCRMKMMBYJQ-UHFFFAOYSA-N 0.000 claims abstract description 38
- 235000012055 fruits and vegetables Nutrition 0.000 claims abstract 2
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 claims description 67
- 239000005742 Bupirimate Substances 0.000 claims description 37
- DSKJPMWIHSOYEA-UHFFFAOYSA-N bupirimate Chemical compound CCCCC1=C(C)N=C(NCC)N=C1OS(=O)(=O)N(C)C DSKJPMWIHSOYEA-UHFFFAOYSA-N 0.000 claims description 37
- 230000000844 anti-bacterial effect Effects 0.000 claims description 23
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- 238000009736 wetting Methods 0.000 claims description 11
- 239000004480 active ingredient Substances 0.000 claims description 8
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- 239000004562 water dispersible granule Substances 0.000 claims description 8
- 238000009472 formulation Methods 0.000 claims description 5
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- 239000005829 Pyriofenone Substances 0.000 abstract description 52
- NMVCBWZLCXANER-UHFFFAOYSA-N pyriofenone Chemical compound COC1=C(OC)C(OC)=CC(C)=C1C(=O)C1=C(C)C(Cl)=CN=C1OC NMVCBWZLCXANER-UHFFFAOYSA-N 0.000 abstract description 52
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Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a pesticide composition containing a diaryl ketone compound, which consists of, as effective components, (A) Pyriofenone and (B) ethirimol or ethirimol sulfonate or dimethirimol. The weight ratio of A to B is 1:50 to 50:1. The pesticide composition has obvious synergism and high control effect, is suitable for controlling various diseases and pests in fruits and vegetables, and is particularly suitable for controlling powdery mildew.
Description
Technical field
The present invention relates to a kind of bactericidal composition, relate in particular to a kind of bactericidal composition and application take diaryl ketone compound and the phonetic phenol of second or bupirimate or dimethirimol as main component.
Background technology
Powdery mildew is the plant disease being caused by the Erysiphaceae in fungi (Erysiphacesae).For example: the Cereal powdery mildew being caused by standing grain powdery mildew (Ery-siphe graminis); The powdery mildew of the various plants such as melon, the beans that caused by Siberian cocklebur monofilament shell (Sphaerotheca fuliginea), crudefiber crop; The grape powdery mildew being caused by grape snag shell (Uncinula necator); The powdery mildew of more than the 80 kind of trees such as the mulberry that caused by hazel ball pin shell (Phyllactinia corylea), pears, persimmon, walnut, chestnut, lichee, papaya papaw; The powdery mildew of the Flowers of Rosa being caused by rose monofilament shell (Sphaerotheca pannosa) etc.
In the control of powdery mildew, the main bactericide such as benzimidazole, triazole type, methoxy acrylate class that rely at present.These medicaments are because long-term use has produced pesticide resistance in various degree, and control efficiency reduces.In addition, the growth to crop in the time that using dosage is large of triazole type medicament has inhibitory action, easily causes poisoning.
Pyriofenone is diaryl ketone series bactericidal agent, molecular formula C
18h
20clNO
5, structural formula is:
Pyriofenone can effectively prevent and treat cereal, the powdery mildew of grape and vegetables.
But the production that Pyriofenone is current and use cost are all higher, and long-term use separately also has very large resistance risk.
Summary of the invention
The object of this invention is to provide a kind of synergistic effect obvious, to the bactericidal composition that powdery mildew control efficiency is good, cost is low, resistance risk is low.
Another object of the present invention is to provide the application of this bactericidal composition.
Inventor is by a large amount of indoor biometrics and field control effectiveness test, surprisingly finds that Pyriofenone and the phonetic phenol of second or bupirimate or dimethirimol in certain proportion after mixture, have significant synergistic effect to diseases such as powdery mildews.
The mechanism of action of the phonetic phenol of described second, bupirimate and dimethirimol is adenosine deaminase inhibitors.
The phonetic phenol of described second
English name: ethirimol
Chemical name: 5-butyl-2-ethylamino-4-hydroxyl-6-methylpyrimidine
Molecular formula: C
11h
19n
3o
Be mainly used in preventing and treating cereal crop powdery mildew, also can prevent and treat ground family crop powdery mildew.
Described bupirimate English name: bupirimate
Chemical name: 5-butyl-2-ethylamino-6-methylpyrimidine-4-base dimethylamino sulphonic acid ester
Molecular formula: C
13h
24n
4o
3s
Be mainly used in preventing and treating various powdery mildews, as apple, grape, cucumber, strawberry, rose, beet powdery mildew.
Described dimethirimol: English name: dimethirimol
Chemical name: 5-normal-butyl-2-dimethylamino-6-methylpyrimidine 4-alcohol
Molecular formula: C
11h
19n
3o
Be mainly used in preventing and treating the powdery mildew of melon, tobacco, tomato, ornamental plants.
The phonetic phenol of second, bupirimate, dimethirimol are bactericide well known in the art, can obtain by various commercial channel.
For overcoming the deficiencies in the prior art, technical scheme of the present invention is to solve like this: a kind of bactericidal composition, contain active ingredient (A) Pyriofenone and (B) the phonetic phenol of second or bupirimate or dimethirimol, A and B mass ratio are 1: 50～50: 1, and preferred proportion is 1: 30～30: 1.
Said composition can be processed into the upper any formulation allowing of agricultural, and formulation has missible oil, microemulsion, aqueous emulsion, suspending agent, wetting powder, water dispersible granules preferably.
In bactericidal composition of the present invention, the mass accumulation percentage composition of A and B is 5%～85%, and all the other are auxiliary agent and filler or thinner.
The formulation of above-mentioned bactericidal composition, except comprising effective constituents A and B, also comprises auxiliary agent and other material that contributes to drug effect to bring into play.Missible oil comprises organic solvent, cosolvent and emulsifier; Microemulsion comprises organic solvent, emulsifier and water; Aqueous emulsion comprises organic solvent, dispersant, emulsifier and water; Suspending agent comprises water, dispersant, thickener, antifreezing agent and wetting agent; Wetting powder comprises wetting agent, dispersant and filler; Water dispersible granules comprises dispersant, disintegrant, filler and wetting agent.Below be all various compositions conventional in pesticidal preparations or that permission is used, be not particularly limited, concrete composition and consumption require to determine by simple experiment according to formula.For example:
Organic solvent can be selected one or more in isopropyl alcohol, dimethylbenzene, DMF, ring ethyl ketone, toluene, dimethyl sulfoxide (DMSO), methyl alcohol, ethanol, trimethyl cyclic ethylene ketone, NOP, 1-METHYLPYRROLIDONE, propyl alcohol, butanols, ethylene glycol, diethylene glycol, ethylene glycol monomethyl ether, butyl ether, ethyl acetate, vegetable oil.
Cosolvent can be selected one or more in 1-METHYLPYRROLIDONE, dimethyl formamide, ethanol, the third ethanol, acetone.
Dispersant can be selected sodium lignin sulfonate, calcium lignosulfonate, pulls open powder, one or more in calcium dodecyl benzene sulfonate, polycarboxylate, alkyl benzene sulfonate calcium salt, alkylphenol polyoxyethylene, aliphatic amine polyoxyethylene ether, polyoxyethylene carboxylate, fatty acid glyceride APEO.
Emulsifier can be selected agricultural emulsifier NO．600 (phenyl phenol polyoxy ethyl ether), No. 1601 (phenethyl phenol polyoxy ethyl polypropylene-base ether) of agriculture breast, No. 500 (alkyl benzene calcium sulfonate) of agriculture breast, OP series phosphate (polyoxyethylene nonylphenol ether phosphate), No. 600 phosphates (phenyl phenol polyoxy ethyl ether phosphate), styrene polyoxyethylene rice ammonium sulfate, alkyl biphenyl ether disulfonic acid magnesium salts, triethanolamine salt, No. 400 (benzyl xylenol polyoxy ethyl ether) of agriculture breast, Nongru-700 number (alkyl phenolic resin polyoxy ethyl ether), No. 36 (phenethyl fluosite polyoxy ethyl ether) of peaceful breast, No. 1600 (phenethyl phenol polyoxy ethyl polypropylene-base ether) of agriculture breast, ethylene oxide-propylene oxide block copolymer, OP series (polyoxyethylene nonylphenol ether). No. 33 (alkylaryl polyoxyethylene polyoxypropylene ether) of agriculture breast, No. 34 (alkylaryl polyoxyethylene poly-oxygen propylene aether) of agriculture breast, sapn series (sorbitan monostearate), tween series (sorbitan fatty acid ester APEO), one or more in AEO series (fat alcohol alcohol APEO).
Antifreezing agent can be selected one or more in glycerine, urea, ethylene glycol, propane diols.
Wetting agent can select that methyl naphthalene sulfonate formaldehyde condensate, lauryl sodium sulfate, Negel, alkyl benzene calcium sulfonate, tea are withered, spaonin powder, silkworm excrement, soapberry powder, bay alcohol radical sodium sulphate, washing powder, pull open one or more in powder.
Disintegrant can be selected one or more in ammonium sulfate, urea, bentonite, aluminium chloride, citric acid, succinic acid, sodium bicarbonate.
Thickener can be selected in xanthans, CMC, methylcellulose, Magnesiumaluminumsilicate, polyvinyl alcohol one or more.
Filler can be selected one or more in White Carbon black, ridge soil, precipitated calcium carbonate, talcum, imvite or convex-concave rod stone, float stone, brickbat, sepiolite or bentonite and non-adsorptivity calcium soil or sand.
Product described in the invention can finished product preparation form provide, and in composition, each material mixes, and the composition of composition also can provide with single dose form, before use, directly in bucket or tank, directly mixes, and is then diluted to required concentration.
Bactericidal composition of the present invention can be used for preventing and treating on the crops such as cucumber, watermelon, pumpkin, muskmelon, joint melon, bottle gourd, balsam pear, sponge gourd, wax gourd, Hami melon, strawberry, capsicum, Chinese cabbage, eggplant, potato, grape by fungus-caused plant diseases such as imperfect fungus, sac fungi, basidiomycetes, be particularly useful for preventing and treating powdery mildew etc.Composition of the present invention can be used by common method, and as cast, injection, spraying, dusting, scatter or be fuming, its amount of application is with weather condition or crop state variation.
Compared with prior art, its advantage is in the present invention: 1, composition synergistic effect is obvious, and preventive effect significantly improves compared with single dose; 2, after drug effect improves, the effective ingredient consumption in field declines, and has reduced production and use cost, has reduced residue of pesticide and environmental pollution; 3, composition is made up of the active ingredient of different mechanism of action, and action site increases, and is conducive to overcome and delays the drug-fast generation of germ.
Embodiment
The pesticide active ingredient of different types of structure being carried out composite, is a kind of effective means that solves at present the problem such as cost and resistance in agricultural chemicals single dose application process.The pesticide active ingredient of different types of structure shows three kinds of type of action after mixing conventionally, i.e. summation action, synergistic effect and antagonism, but be specially which kind of effect, and unpredictable, only have by lot of experiments and just can know.Compound synergic is well filled a prescription, and can improve actual control efficiency, reduces the usage amount of agricultural chemicals, contributes to the generation of delaying drug resistance, is the important means of scientific prevention and cure damage by disease and insect.
The present composition has obvious synergistic function to Powdery Mildew etc., and is not only the simple addition of two kinds of pharmacy effects, and this can be clear that from the result of following toxicity test experiment very much.
Biologicall test example 1: the Toxicity Determination of composition to cucurbits powdery mildew bacterium
Subjects is powdery mildew of cucumber bacterium (Sphaerotheca fuliginea).
Test method: with reference to " the agricultural industry criteria NY/T1156.11-2008 of the People's Republic of China (PRC) ".Choose the consistent potted plant two leaf period cucumber seedlings of growth potential, 5 basins are selected in each processing, number for subsequent use.Under 50PSI pressure, spray with Potter spray tower, every basin 5mL.Test processing is referring to table 1 to table 6, and each medicament arranges 5 concentration gradients.After 24h, carrying out inoculum density is 3 × 10
5the powdery mildew of cucumber bacterium conidial suspension of individual spore/mL.Take the cucumber seedling that sprays equivalent clear water as blank.After inoculation, cucumber seedling being put into greenhouse cultivates.After 10d, according to the morbidity grade scale investigation disease index of powdery mildew of cucumber, and calculate control efficiency.
Powdery mildew of cucumber severity Scaling standard:
0 grade: blade is without scab;
1 grade: lesion area accounts for the area of whole blade below 5%;
3 grades: lesion area account for whole blade area 6%～10%;
5 grades: lesion area accounts for 11%～25% of whole blade area;
7 grades: lesion area accounts for 25%～50% of whole blade area;
9 grades: lesion area accounts for the more than 50% of whole blade area.
The expection effect (being theoretical control efficiency, %) of mixture of active principles use Colby formula determine and with the effect comparison of observing:
Co1by formula: E=X+Y-X*Y/100
E: when active components A working concentration in composition is a, compositions contemplated effect when active component B working concentration is b.
X: effect when active components A using dosage is a.
Y: effect when active component B using dosage is b.
In the time that exceeding expection preventive effect, the actual control efficiency of observing illustrates that mixture has synergistic effect.
Toxicity test result referring to table 1 to table 6.
The pot experiment measurement result to powdery mildew of cucumber such as the phonetic phenol of table 1 second
Table 2Pyriofenone and the composite pot experiment measurement result to powdery mildew of cucumber of the phonetic phenol of second
The pot experiment measurement result to powdery mildew of cucumber such as table 3 bupirimate
Table 4Pyriofenone and the composite pot experiment measurement result to powdery mildew of cucumber of bupirimate
The pot experiment measurement result to powdery mildew of cucumber such as table 5 dimethirimol
Table 6Pyriofenone and the composite pot experiment measurement result to powdery mildew of cucumber of dimethirimol
Result of the test shows, the phonetic phenol of Pyriofenone and second or bupirimate or dimethirimol be the composite powdery mildew of cucumber of preventing and treating within the specific limits, has synergistic effect.
In order to make object of the present invention, technical scheme and advantage clearer, the present invention describes by following concrete formulation examples, but the present invention is limited to absolutely not these examples.The following stated is only the good embodiment of the present invention, only in order to explain the present invention, can not therefore be interpreted as the restriction to the scope of the claims of the present invention.It should be pointed out that all any modifications of making within the spirit and principles in the present invention, be equal to replacement and improvement etc., within all should being included in protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.
Missible oil embodiment
Pesticide active ingredient, emulsifier, solvent are mixed in proportion, and mix and blend in modulation kettle, until completely dissolved, then adds remaining solvent lentamente, after fully stirring, obtains uniform oil phase, makes missible oil product.
Embodiment 1, the phonetic phenol missible oil of 25.5%Pyriofenone second
Pyriofenone25%, the phonetic phenol 0.5% of second, agriculture breast No. 500 2% (emulsifier), dimethylbenzene (solvent) are supplemented to 100%.
Embodiment 2, the phonetic phenol missible oil of 15.5%Pyriofenone second
Pyriofenone15%, the phonetic phenol 0.5% of second, POLYSORBATE 80 3% (emulsifier), toluene (solvent) are supplemented to 100%.
Embodiment 3,25.5%Pyriofenone bupirimate missible oil
Pyriofenone25%, bupirimate 0.5%, agricultural emulsifier NO．600 2% (emulsifier), dimethylbenzene (solvent) are supplemented to 100%.
Embodiment 4,15.5%Pyriofenone bupirimate missible oil
Pyriofenone15%, bupirimate 0.5%, agriculture breast No. 1,600 3% (emulsifier), toluene (solvent) are supplemented to 100%.
Embodiment 5,25.5%Pyriofenone dimethirimol missible oil
Pyriofenone25%, dimethirimol 0.5%, agriculture breast No. 500 2% (emulsifier), dimethylbenzene (solvent) are supplemented to 100%.
Embodiment 6,15.5%Pyriofenone dimethirimol missible oil
Pyriofenone15%, dimethirimol 0.5%, agriculture breast No. 1,601 3% (emulsifier), toluene (solvent) are supplemented to 100%.
Microemulsion, aqueous emulsion embodiment
By each component proportion, solubilization of active ingredient, in solvent and cosolvent, is added to surfactant, mix and make oil phase.Water-soluble component and water are mixed and makes water, then oil phase is added in water or water adds in oil phase, limit edged stirs, and makes microemulsion or aqueous emulsion.
Embodiment 7, the phonetic phenol microemulsion of 5%Pyriofenone second
Pyriofenone2.5%, the phonetic phenol 2.5% of second, cyclohexanol (solvent) 10%, agriculture breast No. 500 8% (emulsifier), agricultural emulsifier NO．600s 5% (emulsifier), agriculture breast No. 1,600 5% (emulsifier), sldium lauryl sulfate 2% (wetting agent), ethylene glycol 5% (antifreezing agent), water are supplemented to 100%.
Embodiment 8,15%Pyriofenone ethirimol emulsion in water
Pyriofenone5%, the phonetic phenol 10% of second, DMF (solvent) 5%, toluene 8% (solvent), glycerine (antifreezing agent) 5%, phenethyl phenol polyethenoxy ether (emulsifier) 10%, calcium dodecyl benzene sulfonate (wetting agent) 5%, water are supplemented to 100%.
Embodiment 9,5%Pyriofenone bupirimate microemulsion
Pyriofenone2%, bupirimate 3%, toluene 8% (solvent), agriculture breast No. 500 8% (emulsifier), agricultural emulsifier NO．600s 5% (emulsifier), agriculture breast No. 1,600 5% (emulsifier), sldium lauryl sulfate 2% (wetting agent), ethylene glycol 5% (antifreezing agent), water are supplemented to 100%.
Embodiment 10,15%Pyriofenone bupirimate aqueous emulsion
Pyriofenone10%, bupirimate 5%, DMF (solvent) 5%, cyclohexanol (solvent) 10%, glycerine (antifreezing agent) 5%, phenethyl phenol polyethenoxy ether (emulsifier) 10%, calcium dodecyl benzene sulfonate (wetting agent) 5%, water are supplemented to 100%.
Embodiment 11,5%Pyriofenone dimethirimol microemulsion
Pyriofenone1%, dimethirimol 4%, toluene 8% (solvent), agriculture breast No. 500 8% (emulsifier), agricultural emulsifier NO．600s 5% (emulsifier), agriculture breast No. 1,600 5% (emulsifier), sldium lauryl sulfate 2% (wetting agent), ethylene glycol 5% (antifreezing agent), water are supplemented to 100%.
Embodiment 12,15%Pyriofenone dimethirimol aqueous emulsion
Pyriofenone7%, dimethirimol 8%, DMF (solvent) 5%, cyclohexanol (solvent) 10%, glycerine (antifreezing agent) 5%, phenethyl phenol polyethenoxy ether (emulsifier) 10%, calcium dodecyl benzene sulfonate (wetting agent) 5%, water are supplemented to 100%.
Suspending agent embodiment
Each components such as active ingredient, dispersant, wetting agent, defoamer, thickener and water are mixed in the ratio of formula, after sand milling or high speed shear, obtain semi-finished product, after analysis, add water and mix filtration and obtain suspending agent.
Embodiment 13, the phonetic phenol suspending agent of 31%Pyriofenone second
Pyriofenone1%, the phonetic phenol 30% of second, sodium lignin sulfonate (dispersant) 5%, alkylphenol polyoxyethylene 8% (wetting agent), propane diols 2% (antifreezing agent), xanthans 1% (thickener), organosilicon 2% (defoamer), water are supplemented to 100%.
Embodiment 14, the phonetic phenol suspending agent of 51%Pyriofenone second
Pyriofenone1%, the phonetic phenol 50% of second, calcium lignosulfonate (dispersant) 5%, alkylphenol polyoxyethylene 8% (wetting agent), propane diols 2% (antifreezing agent), xanthans 1% (thickener), organosilicon 2% (defoamer), water are supplemented to 100%.
Embodiment 15,31%Pyriofenone bupirimate suspending agent
Pyriofenone1%, bupirimate 30%, calcium lignosulfonate (dispersant) 6%, alkylphenol polyoxyethylene 6% (wetting agent), propane diols 2% (antifreezing agent), xanthans 1% (thickener), organosilicon 2% (defoamer), water are supplemented to 100%.
Embodiment 16,51%Pyriofenone bupirimate suspending agent
Pyriofenone1%, bupirimate 50%, sodium lignin sulfonate (dispersant) 5%, alkylphenol polyoxyethylene 6% (wetting agent), propane diols 2% (antifreezing agent), xanthans 1% (thickener), organosilicon 2% (defoamer), water are supplemented to 100%.
Embodiment 17,31%Pyriofenone dimethirimol suspending agent
Pyriofenone1%, dimethirimol 30%, calcium lignosulfonate (dispersant) 8%, alkylphenol polyoxyethylene 8% (wetting agent), propane diols 2% (antifreezing agent), xanthans 1% (thickener), organosilicon 2% (defoamer), water are supplemented to 100%.
Embodiment 18,51%Pyriofenone dimethirimol suspending agent
Pyriofenone1%, dimethirimol 50%, sodium lignin sulfonate (dispersant) 7%, alkylphenol polyoxyethylene 8% (wetting agent), propane diols 2% (antifreezing agent), xanthans 1% (thickener), organosilicon 2% (defoamer), water are supplemented to 100%.
Water dispersible granules embodiment
Pesticide activity component, auxiliary agent and filler are mixed in proportion, through air-flow crushing, then add the water of 15-20%, make water dispersible granules product through kneading, granulation, dry, screening.Capital equipment: mixer, airslide disintegrating mill, kneader, Squeezinggranulator, drying equipment (drying room or fluid bed).
Embodiment 19,85%Pyriofenone ethirimol water dispersible granules
Pyriofenone50%, the phonetic phenol 35% of second, neopelex 2% (wetting agent), sodium lignin sulfonate 4% (dispersant), ammonium sulfate 2% (disintegrant), kaolin (filler) are to 100%.
Embodiment 20,85%Pyriofenone bupirimate water dispersible granules
Pyriofenone30%, bupirimate 55%, neopelex 2% (wetting agent), sodium lignin sulfonate 5% (dispersant), ammonium sulfate 3% (disintegrant), White Carbon black (filler) are to 100%.
Embodiment 21,85%Pyriofenone dimethirimol water dispersible granules
Pyriofenone45%, dimethirimol 40%, neopelex 2% (wetting agent), sodium lignin sulfonate 6% (dispersant), ammonium sulfate 2% (disintegrant), talcum powder (filler) are to 100%.
Wetting powder embodiment
Pesticide activity component, auxiliary agent, filler are mixed in proportion after air-flow crushing and mix and make wetting powder again.Capital equipment: mixer, airslide disintegrating mill.
Embodiment 22, the phonetic phenol wetting powder of 50%Pyriofenone second
Pyriofenone15%, the phonetic phenol 35% of second, bay alcohol radical sodium sulphate 4% (wetting agent), mersolates 7% (dispersant), white carbon 8% (filler), kaolin (filler) are to 100%.
Embodiment 23, the phonetic phenol wetting powder of 35%Pyriofenone second
Pyriofenone25%, the phonetic phenol 10% of second, bay alcohol radical sodium sulphate 4% (wetting agent), mersolates 7% (dispersant), white carbon 8% (filler), talcum powder (filler) are to 100%.
Embodiment 24,50%Pyriofenone bupirimate wetting powder
Pyriofenone10%, bupirimate 40%, bay alcohol radical sodium sulphate 4% (wetting agent), mersolates 7% (dispersant), white carbon 8% (filler), diatomite (filler) are to 100%.
Embodiment 25,35%Pyriofenone bupirimate wetting powder
Pyriofenone30%, bupirimate 5%, bay alcohol radical sodium sulphate 4% (wetting agent), mersolates 7% (dispersant), white carbon 8% (filler), kaolin (filler) are to 100%.
Embodiment 26,50%Pyriofenone dimethirimol wetting powder
Pyriofenone5%, dimethirimol 45%, bay alcohol radical sodium sulphate 4% (wetting agent), mersolates 7% (dispersant), white carbon 8% (filler), diatomite (filler) are to 100%.
Embodiment 27,35%Pyriofenone dimethirimol wetting powder
Pyriofenone15%, dimethirimol 20%, bay alcohol radical sodium sulphate 4% (wetting agent), mersolates 7% (dispersant), white carbon 8% (filler), talcum powder (filler) are to 100%.
The composite field control effectiveness test to powdery mildew of cucumber of field application examples 1:Pyriofenone and the phonetic phenol of second
Test site Guangdong Zhong Shan.Test medicine and consumption are in table 7, and repeat 4 communities of every processing, 20 square metres of each community areas.Carry out dispenser for the first time at disease initial stage of origination, even spraying, till being sprayed onto blade and dripping, is treated to blank with clear water.After 7 days, execute medicine for the second time.Before the medicine for the first time and for the second time incidence of 7 days investigation powderys mildew of cucumber after medicine.Every community adopts 5 samplings, every some investigation two strains, and all blades are investigated in every strain, and the percentage that accounts for whole leaf area with lesion area carrys out classification record.Calculate each processing disease index and control efficiency.
Grade scale:
0 grade: without scab;
1 grade: lesion area accounts for below 5% of whole leaf area;
3 grades: lesion area accounts for the 6%-15% of whole leaf area;
5 grades: lesion area accounts for the 16%-25% of whole leaf area;
7 grades: lesion area accounts for the 26%-50% of whole leaf area;
9 grades: lesion area accounts for the more than 50% of whole leaf area.
Drug effect computational methods:
As can be seen from Table 7: Pyriofenone, the phonetic phenol single dose of second are respectively 76.1%, 73.9% to the preventive effect of powdery mildew of cucumber, and embodiment of the present invention bactericidal composition is all significantly increased in preventive effect, and minimum preventive effect is 85.1%, has been up to 89.1%.The result of field trial fully shows, the phonetic phenol of Pyriofenone and second is composite has significant synergistic function afterwards to powdery mildew of cucumber, and in the situation that mu effective ingredient consumption reduces compared with single dose, control efficiency significantly improves.Therefore, the present composition have reduce costs, the beneficial effect of delaying drug resistance, minimizing spraying times and residue of pesticide.
Table 7Pyriofenone and the composite field test results to powdery mildew of cucumber of the phonetic phenol of second
The composite field control effectiveness test to grape powdery mildew of field application examples 2:Pyriofenone and the phonetic phenol of second
Test site Hengyang, Hunan Province.Test medicine and consumption are in table 8, and repeat 4 communities of every processing, 20 square metres of each community areas.Carry out dispenser for the first time at disease initial stage of origination, even spraying, till being sprayed onto blade and dripping, is treated to blank with clear water.After 7 days, execute medicine for the second time.Before the medicine for the first time and for the second time incidence of 7 days investigation grape powdery mildews after medicine.Every community adopts 5 samplings, every some investigation two strains, and all blades are investigated in every strain, and the percentage that accounts for whole leaf area with lesion area carrys out classification record.Calculate each processing disease index and control efficiency.
Grade scale and drug effect computational methods are with field application examples 1.
As can be seen from Table 8: Pyriofenone, the phonetic phenol single dose of second are respectively 78.2%, 76.1% to the preventive effect of grape powdery mildew, and embodiment of the present invention bactericidal composition is all significantly increased in preventive effect, and minimum preventive effect is 86.2%, has been up to 90.9%.The result of field trial fully shows, the phonetic phenol of Pyriofenone and second is composite has significant synergistic function afterwards to grape powdery mildew, and in the situation that mu effective ingredient consumption reduces compared with single dose, control efficiency obviously improves.Therefore, the present composition have reduce costs, the beneficial effect of delaying drug resistance, minimizing spraying times and residue of pesticide.
Table 8Pyriofenone and the composite field test results to grape powdery mildew of the phonetic phenol of second
The composite field control effectiveness test to powdery mildew of cucumber of field application examples 3:Pyriofenone and bupirimate
Yangjiang, test site Guangdong.Test medicine and consumption are in table 9, and repeat 4 communities of every processing, 20 square metres of each community areas.Carry out dispenser for the first time at disease initial stage of origination, even spraying, till being sprayed onto blade and dripping, is treated to blank with clear water.After 7 days, execute medicine for the second time.Before the medicine for the first time and for the second time incidence of 7 days investigation powderys mildew of cucumber after medicine.Every community adopts 5 samplings, every some investigation two strains, and all blades are investigated in every strain, and the percentage that accounts for whole leaf area with lesion area carrys out classification record.Calculate each processing disease index and control efficiency.
Grade scale:
0 grade: without scab;
1 grade: lesion area accounts for below 5% of whole leaf area;
3 grades: lesion area accounts for the 6%-15% of whole leaf area;
5 grades: lesion area accounts for the 16%-25% of whole leaf area;
7 grades: lesion area accounts for the 26%-50% of whole leaf area;
9 grades: lesion area accounts for the more than 50% of whole leaf area.
Drug effect computational methods:
As can be seen from Table 9: Pyriofenone, bupirimate single dose are respectively 76.4%, 74.5% to the preventive effect of powdery mildew of cucumber, and embodiment of the present invention bactericidal composition is all significantly increased in preventive effect, minimum preventive effect is 85.5%, has been up to 89.8%.The result of field trial fully shows, Pyriofenone and bupirimate are composite has significant synergistic function afterwards to powdery mildew of cucumber, and in the situation that mu effective ingredient consumption reduces compared with single dose, control efficiency significantly improves.Therefore, the present composition have reduce costs, the beneficial effect of delaying drug resistance, minimizing spraying times and residue of pesticide.
Table 9Pyriofenone and the composite field test results to powdery mildew of cucumber of bupirimate
The composite field control effectiveness test to grape powdery mildew of field application examples 4:Pyriofenone and bupirimate
Test site yueyang, hunan.Test medicine and consumption are in table 10, and repeat 4 communities of every processing, 20 square metres of each community areas.Carry out dispenser for the first time at disease initial stage of origination, even spraying, till being sprayed onto blade and dripping, is treated to blank with clear water.After 7 days, execute medicine for the second time.Before the medicine for the first time and for the second time incidence of 7 days investigation grape powdery mildews after medicine.Every community adopts 5 samplings, every some investigation two strains, and all blades are investigated in every strain, and the percentage that accounts for whole leaf area with lesion area carrys out classification record.Calculate each processing disease index and control efficiency.
Grade scale and drug effect computational methods are with field application examples 1.
As can be seen from Table 10: Pyriofenone, bupirimate single dose are respectively 79.5%, 77.1% to the preventive effect of grape powdery mildew, and embodiment of the present invention bactericidal composition is all significantly increased in preventive effect, minimum preventive effect is 87.2%, has been up to 91.8%.The result of field trial fully shows, Pyriofenone and bupirimate are composite has significant synergistic function afterwards to grape powdery mildew, and in the situation that mu effective ingredient consumption reduces compared with single dose, control efficiency obviously improves.Therefore, the present composition have reduce costs, the beneficial effect of delaying drug resistance, minimizing spraying times and residue of pesticide.
Table 10Pyriofenone and the composite field test results to grape powdery mildew of bupirimate
The composite field control effectiveness test to powdery mildew of cucumber of field application examples 5:Pyriofenone and dimethirimol
Test site Foshan.Test medicine and consumption are in table 11, and repeat 4 communities of every processing, 20 square metres of each community areas.Carry out dispenser for the first time at disease initial stage of origination, even spraying, till being sprayed onto blade and dripping, is treated to blank with clear water.After 7 days, execute medicine for the second time.Before the medicine for the first time and for the second time incidence of 7 days investigation powderys mildew of cucumber after medicine.Every community adopts 5 samplings, every some investigation two strains, and all blades are investigated in every strain, and the percentage that accounts for whole leaf area with lesion area carrys out classification record.Calculate each processing disease index and control efficiency.
Grade scale:
0 grade: without scab;
1 grade: lesion area accounts for below 5% of whole leaf area;
3 grades: lesion area accounts for the 6%-15% of whole leaf area;
5 grades: lesion area accounts for the 16%-25% of whole leaf area;
7 grades: lesion area accounts for the 26%-50% of whole leaf area;
9 grades: lesion area accounts for the more than 50% of whole leaf area.
Drug effect computational methods:
As can be seen from Table 11: Pyriofenone, dimethirimol single dose are respectively 76.5%, 74.9% to the preventive effect of powdery mildew of cucumber, and embodiment of the present invention bactericidal composition is all significantly increased in preventive effect, minimum preventive effect is 85.8%, has been up to 90.6%.The result of field trial fully shows, Pyriofenone and dimethirimol are composite has significant synergistic function afterwards to powdery mildew of cucumber, and in the situation that mu effective ingredient consumption reduces compared with single dose, control efficiency significantly improves.Therefore, the present composition have reduce costs, the beneficial effect of delaying drug resistance, minimizing spraying times and residue of pesticide.
Table 11Pyriofenone and the composite field test results to powdery mildew of cucumber of dimethirimol
The composite field control effectiveness test to grape powdery mildew of field application examples 6:Pyriofenone and dimethirimol
Test site yiyang, hunan.Test medicine and consumption are in table 12, and repeat 4 communities of every processing, 20 square metres of each community areas.Carry out dispenser for the first time at disease initial stage of origination, even spraying, till being sprayed onto blade and dripping, is treated to blank with clear water.After 7 days, execute medicine for the second time.Before the medicine for the first time and for the second time incidence of 7 days investigation grape powdery mildews after medicine.Every community adopts 5 samplings, every some investigation two strains, and all blades are investigated in every strain, and the percentage that accounts for whole leaf area with lesion area carrys out classification record.Calculate each processing disease index and control efficiency.
Grade scale and drug effect computational methods are with field application examples 1.
As can be seen from Table 12: Pyriofenone, dimethirimol single dose are respectively 80.9%, 78.2% to the preventive effect of grape powdery mildew, and embodiment of the present invention bactericidal composition is all significantly increased in preventive effect, minimum preventive effect is 88.5%, has been up to 92.8%.The result of field trial fully shows, Pyriofenone and dimethirimol are composite has significant synergistic function afterwards to grape powdery mildew, and in the situation that mu effective ingredient consumption reduces compared with single dose, control efficiency obviously improves.Therefore, the present composition have reduce costs, the beneficial effect of delaying drug resistance, minimizing spraying times and residue of pesticide.
Table 12Pyriofenone and the composite field test results to grape powdery mildew of dimethirimol
Claims (5)
1. a bactericidal composition, is characterized in that: contain active ingredient (A) Py ri ofenone and (B) the phonetic phenol of second or bupirimate or dimethirimol, the mass ratio of A and B is 1: 50～50: 1.
2. bactericidal composition according to claim 1, is characterized in that: A and B mass ratio are 1: 30～30: 1.
3. bactericidal composition according to claim 1 and 2, is characterized in that: in composition, A and B mass accumulation percentage composition are 5%～85%.
4. bactericidal composition according to claim 3, is characterized in that: the formulation of bactericidal composition is missible oil, microemulsion, aqueous emulsion, suspending agent, wetting powder or water dispersible granules.
5. the application of bactericidal composition claimed in claim 1 in gourd, fruit and vegetable controlling powdery mildew.
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