[go: up one dir, main page]

CL2008000306A1 - Dispositivo para administrar medicamentos que comprende un cuerpo con una matriz de una silicona y un medicamento oftalmico, el cuerpo que tiene una superficie externa, un revestimiento de parileno en una parte de la superficie externa del cuerpo; y - Google Patents

Dispositivo para administrar medicamentos que comprende un cuerpo con una matriz de una silicona y un medicamento oftalmico, el cuerpo que tiene una superficie externa, un revestimiento de parileno en una parte de la superficie externa del cuerpo; y

Info

Publication number
CL2008000306A1
CL2008000306A1 CL200800306A CL2008000306A CL2008000306A1 CL 2008000306 A1 CL2008000306 A1 CL 2008000306A1 CL 200800306 A CL200800306 A CL 200800306A CL 2008000306 A CL2008000306 A CL 2008000306A CL 2008000306 A1 CL2008000306 A1 CL 2008000306A1
Authority
CL
Chile
Prior art keywords
external surface
parilen
covering
medicinal product
silicone matrix
Prior art date
Application number
CL200800306A
Other languages
English (en)
Inventor
Theron R Smith Ii Lar Rodstrom
Original Assignee
Alcon Res Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Res Ltd filed Critical Alcon Res Ltd
Publication of CL2008000306A1 publication Critical patent/CL2008000306A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • A61K9/0051Ocular inserts, ocular implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007Methods or devices for eye surgery
    • A61F9/00781Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Prostheses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
CL200800306A 2007-01-31 2008-01-31 Dispositivo para administrar medicamentos que comprende un cuerpo con una matriz de una silicona y un medicamento oftalmico, el cuerpo que tiene una superficie externa, un revestimiento de parileno en una parte de la superficie externa del cuerpo; y CL2008000306A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US89859907P 2007-01-31 2007-01-31

Publications (1)

Publication Number Publication Date
CL2008000306A1 true CL2008000306A1 (es) 2008-09-05

Family

ID=39313204

Family Applications (1)

Application Number Title Priority Date Filing Date
CL200800306A CL2008000306A1 (es) 2007-01-31 2008-01-31 Dispositivo para administrar medicamentos que comprende un cuerpo con una matriz de una silicona y un medicamento oftalmico, el cuerpo que tiene una superficie externa, un revestimiento de parileno en una parte de la superficie externa del cuerpo; y

Country Status (24)

Country Link
US (1) US8753666B2 (es)
EP (1) EP2114531B1 (es)
JP (1) JP2010517630A (es)
KR (1) KR20090104099A (es)
CN (1) CN101600476B (es)
AR (1) AR065235A1 (es)
AU (1) AU2008210541B2 (es)
BR (1) BRPI0807340A2 (es)
CA (1) CA2674913A1 (es)
CL (1) CL2008000306A1 (es)
CY (1) CY1113075T1 (es)
DK (1) DK2114531T3 (es)
ES (1) ES2390991T3 (es)
HK (1) HK1133218A1 (es)
HR (1) HRP20120608T1 (es)
MX (1) MX2009007394A (es)
PL (1) PL2114531T3 (es)
PT (1) PT2114531E (es)
RU (1) RU2459646C2 (es)
SI (1) SI2114531T1 (es)
TW (1) TW200838485A (es)
UY (1) UY30883A1 (es)
WO (1) WO2008094989A2 (es)
ZA (1) ZA200904713B (es)

Families Citing this family (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050232972A1 (en) 2004-04-15 2005-10-20 Steven Odrich Drug delivery via punctal plug
JP2008504938A (ja) 2004-07-02 2008-02-21 レイザー,エリオット 治療媒体送出装置およびその送出装置を用いて治療媒体を眼に送り出す方法
US7887508B2 (en) 2006-03-14 2011-02-15 The University Of Southern California MEMS device and method for delivery of therapeutic agents
ES2717607T3 (es) 2006-03-31 2019-06-24 Mati Therapeutics Inc Estructuras de administración de fármacos y composiciones para el sistema nasolagrimal
JP5555162B2 (ja) * 2007-09-07 2014-07-23 キュー エル ティー インク. 治療薬剤の持続放出のための薬物コア
CN101861135A (zh) 2007-09-07 2010-10-13 Qlt栓塞输送公司 泪道植入物检测
WO2009032328A1 (en) 2007-09-07 2009-03-12 Qlt Plug Delivery, Inc Lacrimal implants and related methods
JP5542691B2 (ja) 2007-12-20 2014-07-09 ユニバーシティ オブ サザン カリフォルニア 治療薬を送達するための装置および方法
EP2266643B1 (en) 2008-01-03 2015-06-17 University Of Southern California Implantable drug-delivery devices, and apparatus and methods for refilling the devices
WO2009134371A2 (en) 2008-04-30 2009-11-05 Qlt Plug Delivery, Inc. Composite lacrimal insert and related methods
US9333297B2 (en) 2008-05-08 2016-05-10 Minipumps, Llc Drug-delivery pump with intelligent control
CN104353150A (zh) 2008-05-08 2015-02-18 迷你泵有限责任公司 可植入泵和用于可植入泵的插管
ES2603027T3 (es) 2008-05-08 2017-02-23 Minipumps, Llc Métodos de fabricación de bombas de administración de fármacos
CN104758999B (zh) * 2008-05-08 2018-08-07 迷你泵有限责任公司 可植入药物传送装置与用于填充该装置的设备和方法
CA2722971C (en) 2008-05-09 2019-05-07 Qlt Plug Delivery, Inc. Sustained release delivery of active agents to treat glaucoma and ocular hypertension
US20090318549A1 (en) * 2008-06-24 2009-12-24 Qlt Plug Delivery, Inc. Combination treatment of glaucoma
US20100104654A1 (en) * 2008-10-27 2010-04-29 Allergan, Inc. Prostaglandin and prostamide drug delivery systems and intraocular therapeutic uses thereof
EP2376019A1 (en) * 2008-12-19 2011-10-19 QLT, Inc. Substance delivering punctum implants and methods
AU2010206610A1 (en) * 2009-01-23 2011-08-11 Qlt Inc. Sustained released delivery of one or more agents
CA2757037C (en) 2009-01-29 2019-08-06 Forsight Vision4, Inc. Posterior segment drug delivery
US8623395B2 (en) 2010-01-29 2014-01-07 Forsight Vision4, Inc. Implantable therapeutic device
SG174133A1 (en) * 2009-02-23 2011-10-28 Quadra Logic Tech Inc Lacrimal implants and related methods
WO2010101758A1 (en) 2009-03-03 2010-09-10 Alcon Research, Ltd. Peri-corneal drug delivery device
US9421127B2 (en) 2009-03-31 2016-08-23 Johnson & Johnson Vision Care, Inc. Punctal plugs
TWI495459B (zh) * 2009-03-31 2015-08-11 Johnson & Johnson Vision Care 淚管塞(二)
US10206813B2 (en) 2009-05-18 2019-02-19 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
EP3785683B1 (en) 2009-05-18 2023-11-01 Dose Medical Corporation Drug eluting ocular implant
CA2764063C (en) 2009-06-03 2019-05-14 Forsight Labs, Llc Anterior segment drug delivery
US8709467B2 (en) 2009-06-26 2014-04-29 Cute Lovable Teddy Bear, Llc. Para-xylylene based microfilm elution devices
JP5758388B2 (ja) 2009-08-18 2015-08-05 ミニパンプス, エルエルシー 適応制御を有する電解質薬物送達ポンプ
US8469934B2 (en) * 2010-01-27 2013-06-25 Alcon Research, Ltd. Pulsatile peri-corneal drug delivery device
US9259351B2 (en) 2010-03-29 2016-02-16 Johnson & Johnson Vision Care, Inc. Punctal plugs
US9259352B2 (en) * 2010-03-29 2016-02-16 Johnson & Johnson Vision Care, Inc. Punctal plugs
BR112012025581A2 (pt) * 2010-04-06 2019-09-24 Allergan Inc implantes de reservatório de liberação sustentada para distribuição de fármaco intracameral
US10617557B2 (en) 2010-08-05 2020-04-14 Forsight Vision4, Inc. Combined drug delivery methods and apparatus
JP6063382B2 (ja) 2010-08-05 2017-01-18 フォーサイト・ビジョン フォー・インコーポレーテッド 治療薬を眼の埋め込み体へと注入するためのシステム
HUE057267T2 (hu) 2010-08-05 2022-05-28 Forsight Vision4 Inc Berendezés szem kezelésére
US8591484B2 (en) 2010-09-15 2013-11-26 AlphaMed, Inc. Lacrimal punctum measurement and occlusion
US20140031769A1 (en) 2010-11-19 2014-01-30 Forsight Vision4, Inc. Therapeutic agent formulations for implanted devices
US10286146B2 (en) 2011-03-14 2019-05-14 Minipumps, Llc Implantable drug pumps and refill devices therefor
US9603997B2 (en) 2011-03-14 2017-03-28 Minipumps, Llc Implantable drug pumps and refill devices therefor
US9919099B2 (en) 2011-03-14 2018-03-20 Minipumps, Llc Implantable drug pumps and refill devices therefor
WO2012149278A1 (en) 2011-04-29 2012-11-01 Allergan, Inc. Sustained release latanoprost implant
EP2726016B1 (en) 2011-06-28 2023-07-19 ForSight Vision4, Inc. An apparatus for collecting a sample of fluid from a reservoir chamber of a therapeutic device for the eye
US20130018360A1 (en) * 2011-07-13 2013-01-17 Marissa Dockendorf Method for delivering ophthalmic drugs
EP2739252A4 (en) * 2011-08-05 2015-08-12 Forsight Vision4 Inc SMALL MOLECULE ADMINISTRATION USING AN IMPLANTABLE THERAPEUTIC DEVICE
US9974685B2 (en) 2011-08-29 2018-05-22 Mati Therapeutics Drug delivery system and methods of treating open angle glaucoma and ocular hypertension
ES2611807T3 (es) 2011-08-29 2017-05-10 Mati Therapeutics Inc. Administración por liberación sostenida de agentes activos para tratar glaucoma e hipertensión ocular
KR102071083B1 (ko) 2011-09-14 2020-01-29 포사이트 비젼5, 인크. 안내 삽입물 장치 및 방법
PL2755600T3 (pl) 2011-09-16 2021-09-20 Forsight Vision4, Inc. Urządzenie do wymiany płynów
US8911227B2 (en) * 2012-01-11 2014-12-16 Johnson & Johnson Vision Care, Inc. Device for injection molding silicone rubber
US10010448B2 (en) 2012-02-03 2018-07-03 Forsight Vision4, Inc. Insertion and removal methods and apparatus for therapeutic devices
FR2986703B1 (fr) * 2012-02-09 2015-01-16 Horus Pharma Dispositif de conditionnement et de distribution d'un produit a usage ophtalmique
EP2844224B1 (en) 2012-05-03 2018-04-11 Mati Therapeutics Inc. Drug delivery system for treating open angle glaucoma and ocular hypertension
RU2520834C2 (ru) * 2012-09-11 2014-06-27 Федеральное Государственное Бюджетное Образовательное Учреждение Высшего Профессионального Образования "Дагестанский Государственный Технический Университет" (Дгту) Способ профилактики и лечения синдрома сухих глаз
DK2911623T3 (da) 2012-10-26 2019-10-28 Forsight Vision5 Inc Oftalmisk system til langvarig frigivelse af lægemiddel til øjet
CA2897197C (en) 2013-01-15 2022-06-07 The Regents Of The University Of Colorado, A Body Corporate Lacrimal system drug delivery device
US9968603B2 (en) 2013-03-14 2018-05-15 Forsight Vision4, Inc. Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant
US20160022695A1 (en) * 2013-03-27 2016-01-28 Forsight Vision5, Inc. Bimatoprost Ocular Silicone Inserts and Methods of Use Thereof
US9526654B2 (en) 2013-03-28 2016-12-27 Forsight Vision4, Inc. Ophthalmic implant for delivering therapeutic substances
WO2015057554A1 (en) * 2013-10-15 2015-04-23 Forsight Vision5, Inc. Formulations and methods for increasing or reducing mucus
JP6655610B2 (ja) 2014-05-29 2020-02-26 グローコス コーポレーション 制御された薬物送達機能を備えるインプラント及びそれを使用する方法
RU2557423C1 (ru) * 2014-06-25 2015-07-20 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт глазных болезней" (ФГБНУ "НИИ глазных болезней") Способ лечения частичного дакриостеноза
US10258503B2 (en) 2014-07-15 2019-04-16 Forsight Vision4, Inc. Ocular implant delivery device and method
SG11201700943TA (en) 2014-08-08 2017-03-30 Forsight Vision4 Inc Stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods of preparation thereof
EP3217924A4 (en) 2014-11-10 2018-07-11 Forsight Vision4, Inc. Expandable drug delivery devices and method of use
WO2016083891A1 (en) * 2014-11-25 2016-06-02 Eyal Sheetrit Compositions and methods for delivering a bio-active agent or bio-active agents
EP3283004A4 (en) 2015-04-13 2018-12-05 Forsight Vision5, Inc. Ocular insert composition of semi-crystalline or crystalline pharmaceutically active agent
CN106264777A (zh) * 2015-06-08 2017-01-04 三鼎生物科技股份有限公司 辅助排泪管
WO2017040853A1 (en) 2015-09-02 2017-03-09 Glaukos Corporation Drug delivery implants with bi-directional delivery capacity
WO2017053751A1 (en) * 2015-09-24 2017-03-30 California Institute Of Technology Implantable device for retaining live cells and providing nutrients thereto
US11564833B2 (en) 2015-09-25 2023-01-31 Glaukos Corporation Punctal implants with controlled drug delivery features and methods of using same
AU2016355345A1 (en) 2015-11-20 2018-05-31 Forsight Vision4, Inc. Porous structures for extended release drug delivery devices
US11857461B2 (en) 2015-11-23 2024-01-02 The Regents Of The University Of Colorado, A Body Corporate Lacrimal system for drug delivery
JP7009384B2 (ja) 2016-04-05 2022-01-25 フォーサイト・ビジョン フォー・インコーポレーテッド 移植可能な眼薬送達デバイス
CA3022830A1 (en) 2016-04-20 2017-10-26 Harold Alexander Heitzmann Bioresorbable ocular drug delivery device
WO2017201255A1 (en) 2016-05-20 2017-11-23 The Regents Of The University Of Colorado, A Body Corporate Lacrimal drug delivery device
CN106667656A (zh) * 2016-06-30 2017-05-17 广州聚明生物科技有限公司 生物可降解泪道栓及其制备方法和应用
CA3065474A1 (en) * 2017-05-30 2018-12-06 Eximore Ltd. Compositions and methods for treating dry eye syndrome delivering antibiotic macrolide
CA3082891A1 (en) 2017-11-21 2019-05-31 Forsight Vision4, Inc. Fluid exchange apparatus for expandable port delivery system and methods of use
US20220125637A1 (en) * 2019-01-18 2022-04-28 Avisi Technologies, Inc. Method and device for treating eye disease
KR102414314B1 (ko) * 2019-02-27 2022-06-30 사회복지법인 삼성생명공익재단 코팅층을 포함하는 안질환용 임플란트
CN111643269B (zh) * 2020-05-14 2024-09-13 海思盖德(苏州)生物医学科技有限公司 一种植入体的多次植入装置及植入方法
USD1033637S1 (en) 2022-01-24 2024-07-02 Forsight Vision4, Inc. Fluid exchange device

Family Cites Families (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3949750A (en) 1974-10-07 1976-04-13 Freeman Jerre M Punctum plug and method for treating keratoconjunctivitis sicca (dry eye) and other ophthalmic aliments using same
US3992518A (en) * 1974-10-24 1976-11-16 G. D. Searle & Co. Method for making a microsealed delivery device
US4053580A (en) * 1975-01-01 1977-10-11 G. D. Searle & Co. Microsealed pharmaceutical delivery device
FR2534580A1 (fr) 1982-10-13 1984-04-20 Synthelabo Derives de phenyl-1 piperidino-2 propanol, leur preparation, et medicaments qui les contiennent
US5053030A (en) * 1984-11-07 1991-10-01 Herrick Robert S Intracanalicular implant for horizontal canalicular blockade treatment of the eye
US5049142A (en) 1984-11-07 1991-09-17 Herrick Robert S Intracanalicular implant for horizontal canalicular blockade treatment of the eye
US4660546A (en) 1984-11-07 1987-04-28 Robert S. Herrick Method for treating for deficiency of tears
US5151444B1 (en) * 1987-09-18 1999-07-06 R Tech Ueno Ltd Ocular hypotensive agents
US4923699A (en) * 1988-06-03 1990-05-08 Kaufman Herbert E Eye treatment suspension
US4915684A (en) 1988-06-21 1990-04-10 Mackeen Donald L Method and apparatus for modulating the flow of lacrimal fluid through a punctum and associated canaliculus
US5296504A (en) 1988-09-06 1994-03-22 Kabi Pharmacia Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
ATE420857T1 (de) 1988-09-06 2009-01-15 Pfizer Health Ab Prostaglandin-derivate zur behandlung von glaukom und ocularer hypertension
SU1671295A1 (ru) * 1988-10-24 1991-08-23 Туркменский государственный медицинский институт Устройство дл регулировани внутриглазного давлени при глаукоме
US4959048A (en) 1989-01-17 1990-09-25 Helix Medical, Inc. Lacrimal duct occluder
US5067491A (en) * 1989-12-08 1991-11-26 Becton, Dickinson And Company Barrier coating on blood contacting devices
US5171270A (en) 1990-03-29 1992-12-15 Herrick Robert S Canalicular implant having a collapsible flared section and method
US5163959A (en) 1990-03-29 1992-11-17 Herrick Robert S Method for treating an eye with a canalicular implant having a collapsible flared section
US5378475A (en) 1991-02-21 1995-01-03 University Of Kentucky Research Foundation Sustained release drug delivery devices
US5283063A (en) 1992-01-31 1994-02-01 Eagle Vision Punctum plug method and apparatus
DK0561073T3 (da) 1992-03-19 2001-11-12 R Tech Ueno Ltd Behandling af øjenhypertension
US5469867A (en) 1992-09-02 1995-11-28 Landec Corporation Cast-in place thermoplastic channel occluder
US5352708A (en) 1992-09-21 1994-10-04 Allergan, Inc. Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
US5922773A (en) 1992-12-04 1999-07-13 The Children's Medical Center Corp. Glaucoma treatment
US5417651A (en) 1993-07-01 1995-05-23 Guena; Nicolas Punctum plug and monocanalicular probe for lacrimal pathology
US5510383A (en) 1993-08-03 1996-04-23 Alcon Laboratories, Inc. Use of cloprostenol, fluprostenol and their salts and esters to treat glaucoma and ocular hypertension
WO1995005161A1 (en) 1993-08-13 1995-02-23 Vitaphore Corporation Hydrogel-based microsphere drug delivery systems
US5423777A (en) 1993-10-27 1995-06-13 Tajiri; Akira Punctum plug
JP3486758B2 (ja) 1994-06-24 2004-01-13 株式会社高研 注入可能な涙小管閉鎖剤
US5723005A (en) 1995-06-07 1998-03-03 Herrick Family Limited Partnership Punctum plug having a collapsible flared section and method
US6149684A (en) 1995-06-07 2000-11-21 Herrick; Robert S. Punctum plug having a thin elongated lip and a distal starting tip and method of using
US5773019A (en) 1995-09-27 1998-06-30 The University Of Kentucky Research Foundation Implantable controlled release device to deliver drugs directly to an internal portion of the body
US5741292A (en) 1995-10-26 1998-04-21 Eagle Vision Punctum dilating and plug inserting instrument with push-button plug release
JP3792775B2 (ja) 1996-04-08 2006-07-05 有限会社エム・エル・シー 涙道挿管器具
JPH1033584A (ja) 1996-07-26 1998-02-10 M L C:Kk 涙道挿管器具
US6016806A (en) 1997-03-27 2000-01-25 Eaglevision, Inc Punctum plug
US6027470A (en) 1998-06-10 2000-02-22 Eagle Vision, Inc. Punctum plug and method for inserting the same into the punctual opening
US6041785A (en) 1997-03-27 2000-03-28 Eaglevision, Inc. Punctum plug
US5830171A (en) 1997-08-12 1998-11-03 Odyssey Medical, Inc. Punctal occluder
NL1008090C2 (nl) 1998-01-22 1999-07-26 Lubberman Bernardus H M Plug voor het afsluiten van een traanbuis.
US6290684B1 (en) 1998-03-02 2001-09-18 Herrick Family Limited Partnership Punctum plug having a collapsible expanded section and distal tip extending substantially perpendicular thereto and method of inserting same
US6196993B1 (en) 1998-04-20 2001-03-06 Eyelab Group, Llc Ophthalmic insert and method for sustained release of medication to the eye
US6306114B1 (en) 1998-06-16 2001-10-23 Eagle Vision, Inc. Valved canalicular plug for lacrimal duct occlusion
DE60020681T9 (de) 1999-02-23 2006-08-31 Angiotech International Ag Zusammensetzungen und verfahren zur verbesserung der integrität von angegriffenen körperpassagewegen und höhlen
US6234175B1 (en) 1999-03-23 2001-05-22 Medennium, Inc. Smart ocular plug design and method of insertion for punctal and intracanalicular implants
US6383192B1 (en) 1999-04-28 2002-05-07 Mlc Limited Company Apparatus for intubation of lacrimal duct
US6344047B1 (en) 2000-02-02 2002-02-05 Eagle Vision Instrument for inserting a punctum plug and method for manufacturing the instrument
JP2004505679A (ja) 2000-08-04 2004-02-26 メデニアム インコーポレーテッド 涙点および涙小管内インプラントのための眼用プラグ
ATE359762T1 (de) * 2001-01-09 2007-05-15 Microchips Inc Flexible mikrochip-vorrichtungen zur ophthalmologischen und anderen applikation
US6827738B2 (en) * 2001-01-30 2004-12-07 Timothy R. Willis Refractive intraocular implant lens and method
US6685626B2 (en) 2001-02-02 2004-02-03 Regeneration Technologies, Inc. Compositions, devices, methods, and kits for induction of adhesions
JP2002263124A (ja) 2001-03-12 2002-09-17 Masashige Nakayama 動物の眼病治療方法及びそれに用いる人工涙管
US6605108B2 (en) * 2001-04-13 2003-08-12 Eagle Vision, Inc. Monocanalicular stent
US20040022853A1 (en) 2001-04-26 2004-02-05 Control Delivery Systems, Inc. Polymer-based, sustained release drug delivery system
US7404825B2 (en) 2001-06-11 2008-07-29 Herrick Ii Robert S Implant capable of forming a differential image in an eye
DE10133870A1 (de) 2001-07-12 2003-02-06 Chris P Lohmann Ophthalmisches Mittel, Verwendung von EGF zur Behandlung von Dry Eye-Syndrom und Insert zur Verabreichung von EGF am Auge
US7204995B2 (en) 2002-01-31 2007-04-17 El-Sherif Dalia M Treatment and control of dry eye by use of biodegradable polymer capsules
US20040043067A1 (en) * 2002-06-19 2004-03-04 Salamone Joseph C. Fluorosiloxane matrix controlled diffusion drug delivery systems
PT1521573E (pt) 2002-07-15 2008-02-08 Alcon Inc Composições de implantes farmacêuticos lipofílicos não poliméricos para utilização intra-ocular
FR2844182B1 (fr) * 2002-09-11 2004-12-03 Humanoptics Ag Bouchon d'obturation d'un canalicule lacrymal
KR20050084599A (ko) 2002-09-26 2005-08-26 안지오테크 인터내셔날 아게 혈관주위 랩
SI1592407T1 (sl) 2003-01-24 2010-04-30 Psivida Inc Naprava s podaljšanim sproĹˇŽŤanjem in postopek za okularno dajanje inhibitorjev karboanhidraze
MXPA05007717A (es) 2003-01-24 2005-09-30 Control Delivery Sys Inc Liberacion controlada de agentes altamente solubles.
ATE476960T1 (de) 2003-05-02 2010-08-15 Surmodics Inc System zur kontrollierten freisetzung eines bioaktiven wirkstoffs im hinteren bereich des auges
WO2005046516A2 (en) * 2003-11-10 2005-05-26 Angiotech International Ag Medical implants and anti-scarring agents
US20050232972A1 (en) 2004-04-15 2005-10-20 Steven Odrich Drug delivery via punctal plug
US7799336B2 (en) * 2004-04-30 2010-09-21 Allergan, Inc. Hypotensive lipid-containing biodegradable intraocular implants and related methods
US8722097B2 (en) 2004-04-30 2014-05-13 Allergan, Inc. Oil-in-water method for making polymeric implants containing a hypotensive lipid
US7252006B2 (en) * 2004-06-07 2007-08-07 California Institute Of Technology Implantable mechanical pressure sensor and method of manufacturing the same
JP2008504938A (ja) 2004-07-02 2008-02-21 レイザー,エリオット 治療媒体送出装置およびその送出装置を用いて治療媒体を眼に送り出す方法
US7117870B2 (en) 2004-07-26 2006-10-10 Clarity Corporation Lacrimal insert having reservoir with controlled release of medication and method of manufacturing the same
US7575781B2 (en) * 2004-08-03 2009-08-18 Sur Modics, Inc. Method for depositing a polymeric coating on a substrate
US20080038317A1 (en) * 2004-09-10 2008-02-14 Chin-Ming Chang Therapeutic Lacrimal Canalicular Inserts And Related Methods
ES2717607T3 (es) 2006-03-31 2019-06-24 Mati Therapeutics Inc Estructuras de administración de fármacos y composiciones para el sistema nasolagrimal
US9474645B2 (en) 2006-06-21 2016-10-25 Johnson & Johnson Vision Care, Inc. Punctal plugs for the delivery of active agents
US9173773B2 (en) 2006-06-21 2015-11-03 Johnson & Johnson Vision Care, Inc. Punctal plugs for the delivery of active agents
US20080045911A1 (en) 2006-06-21 2008-02-21 Borgia Maureen J Punctal plugs for the delivery of active agents
US20080086101A1 (en) 2006-08-25 2008-04-10 David Freilich Ophthalmic insert

Also Published As

Publication number Publication date
US8753666B2 (en) 2014-06-17
EP2114531A2 (en) 2009-11-11
US20080181930A1 (en) 2008-07-31
BRPI0807340A2 (pt) 2017-05-02
CN101600476B (zh) 2013-08-21
AU2008210541A1 (en) 2008-08-07
CY1113075T1 (el) 2016-04-13
JP2010517630A (ja) 2010-05-27
EP2114531B1 (en) 2012-07-11
WO2008094989A2 (en) 2008-08-07
CN101600476A (zh) 2009-12-09
TW200838485A (en) 2008-10-01
RU2009132493A (ru) 2011-03-10
ZA200904713B (en) 2010-09-29
UY30883A1 (es) 2008-05-31
RU2459646C2 (ru) 2012-08-27
ES2390991T3 (es) 2012-11-20
CA2674913A1 (en) 2008-08-07
MX2009007394A (es) 2009-08-12
WO2008094989A3 (en) 2009-04-30
SI2114531T1 (sl) 2012-09-28
AU2008210541B2 (en) 2013-09-26
DK2114531T3 (da) 2012-07-30
AR065235A1 (es) 2009-05-27
PT2114531E (pt) 2012-10-09
HK1133218A1 (en) 2010-03-19
KR20090104099A (ko) 2009-10-05
PL2114531T3 (pl) 2012-10-31
HRP20120608T1 (hr) 2012-08-31

Similar Documents

Publication Publication Date Title
CL2008000306A1 (es) Dispositivo para administrar medicamentos que comprende un cuerpo con una matriz de una silicona y un medicamento oftalmico, el cuerpo que tiene una superficie externa, un revestimiento de parileno en una parte de la superficie externa del cuerpo; y
UY33026A (es) Composicion farmaceutica que comprende un agonista de glp-1, una insulina y metionina
BR112018010671A8 (pt) dispositivos e métodos de distribuição de fármaco com mudança de forma
EP3999144A4 (en) INTEGRATED MEDICATION INFUSION DEVICE
AR089893A1 (es) Adaptador para acoplar a un recipiente medico
BR112015014902A2 (pt) montagem de empacotamento para dispositivos de entrega de fármaco
UY30722A1 (es) Mejoras en y relacionadas con mecanismos accionadores adecuados para usarse en dispositivos de descarga de farmacos.
BRPI0821876B8 (pt) tampa de ponta e seringa
EP4234036A3 (en) Multi-unit drug delivery devices
BRPI0815577A2 (pt) Peptídeo foxm1 e agente medicinal compreendendo o mesmo.
AR063838A1 (es) Mejoras en y relacionadas con mecanismos accionadores adecuados para usarse en dispositivos de descarga de farmacos
AR063837A1 (es) Mejoras en y relacionadas con mecanismos accionadores adecuados para usarse en dispositivos de descarga de farmacos
CL2012001404A1 (es) Composicion farmaceutica que comprende microparticulas compresibles recubiertas de farmaco, un recubrimiento de liberacion modificada, enmascarador del sabor, que comprende un polimero insoluble en agua y un recubrimiento compresible con un edulcorante no polimero sobre ella; composicion de tabletas de rapida desintegracion oral; metodo de preparacion.
DOP2012000132A (es) Composicion farmaceutica que comprende un agonista de glp-1 y metionina
CR20130201A (es) Dispositivos para suministrar un medicamento y método para aliviar el dolor
MY161502A (en) Dose setting mechanism with maximum dose limiting element
AR086930A1 (es) Conjunto de soporte de cartucho para dispositivos de administracion de farmacos
AR078020A1 (es) Dispositivo de administracion pericorneal de farmacos
CR20180117A (es) Envase blister
EP3903856A4 (en) DRUG DELIVERY DEVICE AND DRUG DELIVERY SYSTEM
CL2014003148A1 (es) Composición farmacéutica acuosa que contiene un agente terapéutico biológico y guanidina o un derivado de la guanidina y una inyección que incluye la composición.
MX386380B (es) Forma de dosis de disolución rápida de vacuna oral que usa almidón.
AR098514A1 (es) Soporte de implemento del cuidado oral y sistema del cuidado oral que comprende el mismo
EP3597235A4 (en) MEDICINAL LIQUID INJECTION DEVICE
CL2015001615A1 (es) Una composicion farmaceutica que comprende vortioxetina y donepezilo junto con un excipiente farmaceuticamente aceptable; y su uso para el tratamiento de disfuncion cognitiva, demencia en la enfermedad de alzheimer, disfuncion cognitiva asociada a la depresion y a la esquizofrenia, entre otras enfermedades.