BR0314878A - Derivados de [1,4] benzodioxino[2,3-e] isoindol substituìdos, seu processo de preparo e as composições farmacêuticas que os contêm - Google Patents
Derivados de [1,4] benzodioxino[2,3-e] isoindol substituìdos, seu processo de preparo e as composições farmacêuticas que os contêmInfo
- Publication number
- BR0314878A BR0314878A BR0314878-5A BR0314878A BR0314878A BR 0314878 A BR0314878 A BR 0314878A BR 0314878 A BR0314878 A BR 0314878A BR 0314878 A BR0314878 A BR 0314878A
- Authority
- BR
- Brazil
- Prior art keywords
- straight
- group
- branched
- benzodioxino
- hydrogen atom
- Prior art date
Links
- KNIDIOJLHQWUMR-UHFFFAOYSA-N 2h-[1,4]benzodioxino[2,3-e]isoindole Chemical class C1=CC2=CNC=C2C2=C1OC1=CC=CC=C1O2 KNIDIOJLHQWUMR-UHFFFAOYSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000003161 (C1-C6) alkylene group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- -1 straight or branched Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
"DERIVADOS DE [1,4]BENZODIOXINO[2,3-e]ISOINDOL SUBSTITUìDOS, SEU PROCESSO DE PREPARO E AS COMPOSIçõES FARMACêUTICAS QUE OS CONTêM". Compostos de fórmula (I), na qual: A é tal como definido na descrição, Y representa um grupamento escolhido dentre o átomo de oxigênio ou grupamento metileno, R~ 2~ representa um átomo de hidrogênio, e nesse caso R~ 3~ representa um grupamento escolhido dentre um átomo de hidrogênio, grupamento alquila (C~ 1~-C~ 6~), linear ou ramificado, arila, arilalquila (C~ 1~-C~ 6~), linear ou ramificado, ou SO~ 2~ CF~ 3~, ou bem R~ 2~ e R~ 3~ formam uma ligação, R~ 1~, representa um grupamento escolhido dentre o átomo de hidrogênio, grupamento alquila (C~ 1~-C~ 6~), linear ou ramificado, arila, arilalquila (C~ 1~-C~ 6~), linear ou ramificado, ou uma cadeia alquileno (C~ 1~-C~ 6~), linear ou ramificado, Z~ 1~ e Z~ 1~ e Z~ 2~ representam, cada um, um átomo de hidrogênio ou Z~ 1~, e Z~ 2~ formam juntos com os átomos de carbono que os portam, um grupamento fenila. Medicamentos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0212965A FR2845997B1 (fr) | 2002-10-18 | 2002-10-18 | Nouveaux derives de[1,4]benzodioxino[2,3-e]isoindole substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| PCT/FR2003/003069 WO2004037831A1 (fr) | 2002-10-18 | 2003-10-17 | NOUVEAUX DERIVES DE [1,4]BENZODIOXINO[2,3-e]ISOINDOLE SUBSTITUES, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0314878A true BR0314878A (pt) | 2005-08-02 |
Family
ID=32050502
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0314878-5A BR0314878A (pt) | 2002-10-18 | 2003-10-17 | Derivados de [1,4] benzodioxino[2,3-e] isoindol substituìdos, seu processo de preparo e as composições farmacêuticas que os contêm |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US7202255B2 (pt) |
| EP (1) | EP1587810B1 (pt) |
| JP (1) | JP2006507280A (pt) |
| KR (1) | KR100695600B1 (pt) |
| CN (1) | CN100412076C (pt) |
| AR (1) | AR041654A1 (pt) |
| AT (1) | ATE344800T1 (pt) |
| AU (1) | AU2003301532A1 (pt) |
| BR (1) | BR0314878A (pt) |
| CA (1) | CA2502488A1 (pt) |
| CY (1) | CY1105972T1 (pt) |
| DE (1) | DE60309605T2 (pt) |
| DK (1) | DK1587810T3 (pt) |
| EA (1) | EA008498B1 (pt) |
| ES (1) | ES2276160T3 (pt) |
| FR (1) | FR2845997B1 (pt) |
| GE (1) | GEP20074102B (pt) |
| MA (1) | MA27340A1 (pt) |
| MX (1) | MXPA05004113A (pt) |
| MY (1) | MY136142A (pt) |
| NO (1) | NO20052330D0 (pt) |
| NZ (1) | NZ539195A (pt) |
| PL (1) | PL375956A1 (pt) |
| PT (1) | PT1587810E (pt) |
| SI (1) | SI1587810T1 (pt) |
| UA (1) | UA79997C2 (pt) |
| WO (1) | WO2004037831A1 (pt) |
| ZA (1) | ZA200502829B (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2010232646A1 (en) * | 2009-03-31 | 2011-10-20 | Arqule, Inc. | Pyrazolo-pyrrolopyridine-dione derivatives useful in the treatment of cancer |
| CN103086947A (zh) * | 2011-11-04 | 2013-05-08 | 赵庆春 | 具有抗血管生成活性的邻苯二甲酰亚胺类化合物及其用途 |
| KR101614599B1 (ko) * | 2014-04-09 | 2016-04-21 | 주식회사 두산 | 유기 화합물 및 이를 포함하는 유기 전계 발광 소자 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5705511A (en) * | 1994-10-14 | 1998-01-06 | Cephalon, Inc. | Fused pyrrolocarbazoles |
| WO1998009967A1 (fr) * | 1996-09-09 | 1998-03-12 | Kyowa Hakko Kogyo Co., Ltd. | Derives de pyrrolocarbazole |
| FR2755691B1 (fr) * | 1996-11-08 | 1998-12-04 | Adir | Nouveaux derives 7,12-dioxa-benzo[a]anthraceniques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
-
2002
- 2002-10-18 FR FR0212965A patent/FR2845997B1/fr not_active Expired - Fee Related
-
2003
- 2003-09-26 MY MYPI20033682A patent/MY136142A/en unknown
- 2003-10-17 NZ NZ539195A patent/NZ539195A/en unknown
- 2003-10-17 PT PT03809363T patent/PT1587810E/pt unknown
- 2003-10-17 UA UAA200504634A patent/UA79997C2/uk unknown
- 2003-10-17 MX MXPA05004113A patent/MXPA05004113A/es active IP Right Grant
- 2003-10-17 DE DE60309605T patent/DE60309605T2/de not_active Expired - Fee Related
- 2003-10-17 EP EP03809363A patent/EP1587810B1/fr not_active Expired - Lifetime
- 2003-10-17 DK DK03809363T patent/DK1587810T3/da active
- 2003-10-17 EA EA200500573A patent/EA008498B1/ru not_active IP Right Cessation
- 2003-10-17 GE GEAP20038800A patent/GEP20074102B/en unknown
- 2003-10-17 AR ARP030103789A patent/AR041654A1/es not_active Application Discontinuation
- 2003-10-17 AU AU2003301532A patent/AU2003301532A1/en not_active Abandoned
- 2003-10-17 AT AT03809363T patent/ATE344800T1/de not_active IP Right Cessation
- 2003-10-17 WO PCT/FR2003/003069 patent/WO2004037831A1/fr active IP Right Grant
- 2003-10-17 CA CA002502488A patent/CA2502488A1/fr not_active Abandoned
- 2003-10-17 KR KR1020057006695A patent/KR100695600B1/ko not_active IP Right Cessation
- 2003-10-17 JP JP2004546098A patent/JP2006507280A/ja active Pending
- 2003-10-17 ES ES03809363T patent/ES2276160T3/es not_active Expired - Lifetime
- 2003-10-17 SI SI200330583T patent/SI1587810T1/sl unknown
- 2003-10-17 CN CNB2003801013475A patent/CN100412076C/zh not_active Expired - Fee Related
- 2003-10-17 US US10/531,393 patent/US7202255B2/en not_active Expired - Fee Related
- 2003-10-17 PL PL03375956A patent/PL375956A1/xx not_active Application Discontinuation
- 2003-10-17 BR BR0314878-5A patent/BR0314878A/pt not_active IP Right Cessation
-
2005
- 2005-03-30 MA MA28179A patent/MA27340A1/fr unknown
- 2005-04-07 ZA ZA200502829A patent/ZA200502829B/en unknown
- 2005-05-12 NO NO20052330A patent/NO20052330D0/no not_active Application Discontinuation
-
2007
- 2007-01-31 CY CY20071100132T patent/CY1105972T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE 6A. E 7A. ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2069 DE 31/08/2010. |