EA200500573A1 - НОВЫЕ ЗАМЕЩЁННЫЕ [1,4]БЕНЗДИОКСИНО[2,3-e]ИЗОИНДОЛА, СПОСОБ ИХ ПОЛУЧЕНИЯ И ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ, КОТОРЫЕ ИХ СОДЕРЖАТ - Google Patents
НОВЫЕ ЗАМЕЩЁННЫЕ [1,4]БЕНЗДИОКСИНО[2,3-e]ИЗОИНДОЛА, СПОСОБ ИХ ПОЛУЧЕНИЯ И ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ, КОТОРЫЕ ИХ СОДЕРЖАТInfo
- Publication number
- EA200500573A1 EA200500573A1 EA200500573A EA200500573A EA200500573A1 EA 200500573 A1 EA200500573 A1 EA 200500573A1 EA 200500573 A EA200500573 A EA 200500573A EA 200500573 A EA200500573 A EA 200500573A EA 200500573 A1 EA200500573 A1 EA 200500573A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- branched
- linear
- alkyl
- aryl
- hydrogen atom
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Соединения формулы (I)в которой A имеет значения, указанные в описании,Y представляет собой группу, выбранную из атома кислорода и метиленовой группы,Rпредставляет собой атом водорода и в этом случае Rпредставляет собой группу, выбранную из атома водорода и таких групп, как линейный или разветвленный C-C-алкил, арил, арил-C-C-алкил (в котором алкильная часть является линейной или разветвленной) и SOCF, или Rи Rобразуют связь,Rпредставляет собой группу, выбранную из атома водорода и таких групп, как линейный или разветвленный C-C-алкил, арил и арил-C-C-алкил (в котором алкильная часть является линейной или разветвленной) или линейную или разветвленную C-C-алкиленовую цепь,Zи Zкаждый представляет собой атом водорода илиZи Zвместе с атомами углерода, с которыми они связаны, образуют фенильную группу.Лекарственные средства.Международная заявка была опубликована вместе с отчетом о международном поиске.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0212965A FR2845997B1 (fr) | 2002-10-18 | 2002-10-18 | Nouveaux derives de[1,4]benzodioxino[2,3-e]isoindole substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| PCT/FR2003/003069 WO2004037831A1 (fr) | 2002-10-18 | 2003-10-17 | NOUVEAUX DERIVES DE [1,4]BENZODIOXINO[2,3-e]ISOINDOLE SUBSTITUES, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA200500573A1 true EA200500573A1 (ru) | 2005-12-29 |
| EA008498B1 EA008498B1 (ru) | 2007-06-29 |
Family
ID=32050502
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200500573A EA008498B1 (ru) | 2002-10-18 | 2003-10-17 | Замещённые соединения [1,4]бенздиоксино[2,3-e]изоиндола, способ их получения и фармацевтические композиции, которые их содержат |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US7202255B2 (ru) |
| EP (1) | EP1587810B1 (ru) |
| JP (1) | JP2006507280A (ru) |
| KR (1) | KR100695600B1 (ru) |
| CN (1) | CN100412076C (ru) |
| AR (1) | AR041654A1 (ru) |
| AT (1) | ATE344800T1 (ru) |
| AU (1) | AU2003301532A1 (ru) |
| BR (1) | BR0314878A (ru) |
| CA (1) | CA2502488A1 (ru) |
| CY (1) | CY1105972T1 (ru) |
| DE (1) | DE60309605T2 (ru) |
| DK (1) | DK1587810T3 (ru) |
| EA (1) | EA008498B1 (ru) |
| ES (1) | ES2276160T3 (ru) |
| FR (1) | FR2845997B1 (ru) |
| GE (1) | GEP20074102B (ru) |
| MA (1) | MA27340A1 (ru) |
| MX (1) | MXPA05004113A (ru) |
| MY (1) | MY136142A (ru) |
| NO (1) | NO20052330L (ru) |
| NZ (1) | NZ539195A (ru) |
| PL (1) | PL375956A1 (ru) |
| PT (1) | PT1587810E (ru) |
| SI (1) | SI1587810T1 (ru) |
| UA (1) | UA79997C2 (ru) |
| WO (1) | WO2004037831A1 (ru) |
| ZA (1) | ZA200502829B (ru) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201100423A (en) * | 2009-03-31 | 2011-01-01 | Arqule Inc | Substituted pyrazolo-pyrrolo-pyridine-dione compounds |
| CN103086947A (zh) * | 2011-11-04 | 2013-05-08 | 赵庆春 | 具有抗血管生成活性的邻苯二甲酰亚胺类化合物及其用途 |
| KR101614599B1 (ko) * | 2014-04-09 | 2016-04-21 | 주식회사 두산 | 유기 화합물 및 이를 포함하는 유기 전계 발광 소자 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5705511A (en) * | 1994-10-14 | 1998-01-06 | Cephalon, Inc. | Fused pyrrolocarbazoles |
| WO1998009967A1 (fr) * | 1996-09-09 | 1998-03-12 | Kyowa Hakko Kogyo Co., Ltd. | Derives de pyrrolocarbazole |
| FR2755691B1 (fr) * | 1996-11-08 | 1998-12-04 | Adir | Nouveaux derives 7,12-dioxa-benzo[a]anthraceniques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
-
2002
- 2002-10-18 FR FR0212965A patent/FR2845997B1/fr not_active Expired - Fee Related
-
2003
- 2003-09-26 MY MYPI20033682A patent/MY136142A/en unknown
- 2003-10-17 DE DE60309605T patent/DE60309605T2/de not_active Expired - Fee Related
- 2003-10-17 DK DK03809363T patent/DK1587810T3/da active
- 2003-10-17 EP EP03809363A patent/EP1587810B1/fr not_active Expired - Lifetime
- 2003-10-17 JP JP2004546098A patent/JP2006507280A/ja active Pending
- 2003-10-17 BR BR0314878-5A patent/BR0314878A/pt not_active IP Right Cessation
- 2003-10-17 EA EA200500573A patent/EA008498B1/ru not_active IP Right Cessation
- 2003-10-17 ES ES03809363T patent/ES2276160T3/es not_active Expired - Lifetime
- 2003-10-17 PL PL03375956A patent/PL375956A1/xx not_active Application Discontinuation
- 2003-10-17 CA CA002502488A patent/CA2502488A1/fr not_active Abandoned
- 2003-10-17 KR KR1020057006695A patent/KR100695600B1/ko not_active Expired - Fee Related
- 2003-10-17 CN CNB2003801013475A patent/CN100412076C/zh not_active Expired - Fee Related
- 2003-10-17 AT AT03809363T patent/ATE344800T1/de not_active IP Right Cessation
- 2003-10-17 MX MXPA05004113A patent/MXPA05004113A/es active IP Right Grant
- 2003-10-17 PT PT03809363T patent/PT1587810E/pt unknown
- 2003-10-17 US US10/531,393 patent/US7202255B2/en not_active Expired - Fee Related
- 2003-10-17 NZ NZ539195A patent/NZ539195A/en unknown
- 2003-10-17 AR ARP030103789A patent/AR041654A1/es not_active Application Discontinuation
- 2003-10-17 AU AU2003301532A patent/AU2003301532A1/en not_active Abandoned
- 2003-10-17 UA UAA200504634A patent/UA79997C2/uk unknown
- 2003-10-17 WO PCT/FR2003/003069 patent/WO2004037831A1/fr active IP Right Grant
- 2003-10-17 SI SI200330583T patent/SI1587810T1/sl unknown
- 2003-10-17 GE GEAP20038800A patent/GEP20074102B/en unknown
-
2005
- 2005-03-30 MA MA28179A patent/MA27340A1/fr unknown
- 2005-04-07 ZA ZA200502829A patent/ZA200502829B/en unknown
- 2005-05-12 NO NO20052330A patent/NO20052330L/no not_active Application Discontinuation
-
2007
- 2007-01-31 CY CY20071100132T patent/CY1105972T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG MD TJ TM RU |