BE895751A - Nouveaux derives du benzothiophene, leur preparation et leur utilisation comme medicaments - Google Patents

Nouveaux derives du benzothiophene, leur preparation et leur utilisation comme medicaments

Info

Publication number: BE895751A
Authority: BE; Belgium
Prior art keywords: medicaments; preparation; benzothiophene derivatives; novel benzothiophene; novel
Prior art date: 1982-02-03

Application number

BE1/10709A

Other languages

English (en)

Original Assignee

Sandoz Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-02-03

Filing date

1983-01-31

Publication date

1983-08-01

1983-01-31 Application filed by Sandoz Sa filed Critical Sandoz Sa

1983-08-01 Publication of BE895751A publication Critical patent/BE895751A/fr

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
- C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
- C07C29/40—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/56—Radicals substituted by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/58—Radicals substituted by nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Pharmacology & Pharmacy (AREA)
Communicable Diseases (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heat-Exchange Devices With Radiators And Conduit Assemblies (AREA)
Physical Or Chemical Processes And Apparatus (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)
Refuge Islands, Traffic Blockers, Or Guard Fence (AREA)

BE1/10709A 1982-02-03 1983-01-31 Nouveaux derives du benzothiophene, leur preparation et leur utilisation comme medicaments BE895751A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH656/82A CH653028A5 (de)	1982-02-03	1982-02-03	Benzthiophenallylamin-verbindungen und verfahren zu ihrer herstellung.

Publications (1)

Publication Number	Publication Date
BE895751A true BE895751A (fr)	1983-08-01

Family

ID=4192086

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BE1/10709A BE895751A (fr)	1982-02-03	1983-01-31	Nouveaux derives du benzothiophene, leur preparation et leur utilisation comme medicaments

Country Status (28)

Country	Link
US (2)	US4474141A (fr)
JP (1)	JPS58146580A (fr)
AT (1)	AT391865B (fr)
AU (1)	AU569838B2 (fr)
BE (1)	BE895751A (fr)
CA (1)	CA1193271A (fr)
CH (1)	CH653028A5 (fr)
CY (1)	CY1485A (fr)
DE (1)	DE3302814A1 (fr)
DK (1)	DK160043C (fr)
ES (1)	ES8403473A1 (fr)
FI (1)	FI80689C (fr)
FR (1)	FR2520741B1 (fr)
GB (1)	GB2116171B (fr)
HK (1)	HK47789A (fr)
HU (1)	HU190886B (fr)
IE (1)	IE55073B1 (fr)
IL (1)	IL67813A0 (fr)
IT (1)	IT1197565B (fr)
KE (1)	KE3877A (fr)
MY (1)	MY8700167A (fr)
NL (1)	NL8300350A (fr)
NZ (1)	NZ203144A (fr)
PH (1)	PH22625A (fr)
PT (1)	PT76175B (fr)
SE (1)	SE455095B (fr)
SG (1)	SG16289G (fr)
ZA (1)	ZA83733B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH672311A5 (fr) *	1985-09-14	1989-11-15	Sandoz Ag
EP0404721A3 (fr) *	1989-06-20	1991-12-27	Ciba-Geigy Ag	Microbicides
CA2038633A1 (fr) *	1990-03-20	1991-09-21	Yoshimi Tsuchiya	Derives d'amines a substitution qui ont une activite antihyperlipemique
FR2695930B1 (fr) *	1992-09-22	1994-12-23	Sanofi Elf	Dérivé du 2-éthyl benzo[b]thiophène, son procédé de préparation et son utilisation comme intermédiaire de synthèse.
JP4759500B2 (ja) *	2001-02-22	2011-08-31	帝人株式会社	ベンゾ［ｂ］チオフェン誘導体、およびその製造方法
KR20080058435A (ko) *	2005-10-27	2008-06-25	데이진 화-마 가부시키가이샤	벤조[ｂ]티오펜 유도체 및 그 제조 방법
CN102898314B (zh) *	2012-11-13	2014-09-03	山东铂源药业有限公司	一种盐酸特比萘芬的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1250019B (fr) *	1963-07-19
CH442353A (de) *	1964-04-16	1967-08-31	Sandoz Ag	Verfahren zur Herstellung von neuen Benzothiophen-Derivaten
US3930537A (en) *	1974-05-06	1976-01-06	The United States Of America As Represented By The United States Energy Research And Development Administration	Heat exchanger
EP0000896B1 (fr) *	1977-08-19	1982-10-13	Sandoz Ag	Propényl-amines, procédés pour leur préparation et les compositions pharmaceutiques les contenant
CY1410A (en) *	1979-08-22	1988-04-22	Sandoz Ag	Propenylamines, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals

1982
- 1982-02-03 CH CH656/82A patent/CH653028A5/de not_active IP Right Cessation
1983
- 1983-01-25 US US06/460,782 patent/US4474141A/en not_active Expired - Lifetime
- 1983-01-27 FI FI830297A patent/FI80689C/fi not_active IP Right Cessation
- 1983-01-28 PH PH28446A patent/PH22625A/en unknown
- 1983-01-28 DE DE19833302814 patent/DE3302814A1/de active Granted
- 1983-01-31 GB GB08302573A patent/GB2116171B/en not_active Expired
- 1983-01-31 NL NL8300350A patent/NL8300350A/nl not_active Application Discontinuation
- 1983-01-31 FR FR8301586A patent/FR2520741B1/fr not_active Expired
- 1983-01-31 BE BE1/10709A patent/BE895751A/fr not_active IP Right Cessation
- 1983-02-01 CA CA000420692A patent/CA1193271A/fr not_active Expired
- 1983-02-01 NZ NZ203144A patent/NZ203144A/en unknown
- 1983-02-01 SE SE8300535A patent/SE455095B/sv not_active IP Right Cessation
- 1983-02-01 IL IL67813A patent/IL67813A0/xx not_active IP Right Cessation
- 1983-02-01 AU AU10897/83A patent/AU569838B2/en not_active Ceased
- 1983-02-01 DK DK040883A patent/DK160043C/da not_active IP Right Cessation
- 1983-02-01 PT PT76175A patent/PT76175B/pt unknown
- 1983-02-02 AT AT0034983A patent/AT391865B/de not_active IP Right Cessation
- 1983-02-02 IE IE202/83A patent/IE55073B1/en not_active IP Right Cessation
- 1983-02-02 ES ES519477A patent/ES8403473A1/es not_active Expired
- 1983-02-02 JP JP58016866A patent/JPS58146580A/ja active Granted
- 1983-02-02 HU HU83357A patent/HU190886B/hu not_active IP Right Cessation
- 1983-02-03 IT IT47666/83A patent/IT1197565B/it active
- 1983-02-03 ZA ZA83733A patent/ZA83733B/xx unknown
1986
- 1986-05-01 US US06/858,417 patent/US4737516A/en not_active Expired - Fee Related
1987
- 1987-12-30 MY MY167/87A patent/MY8700167A/xx unknown
1989
- 1989-03-27 SG SG162/89A patent/SG16289G/en unknown
- 1989-04-26 KE KE3877A patent/KE3877A/xx unknown
- 1989-06-15 HK HK477/89A patent/HK47789A/xx unknown
- 1989-12-08 CY CY1485A patent/CY1485A/xx unknown

Also Published As

Publication number	Publication date
IL67813A0 (en)	1983-06-15
DE3302814A1 (de)	1983-08-11
GB8302573D0 (en)	1983-03-02
SE455095B (sv)	1988-06-20
CH653028A5 (de)	1985-12-13
GB2116171A (en)	1983-09-21
SE8300535D0 (sv)	1983-02-01
AU1089783A (en)	1983-08-11
PH22625A (en)	1988-10-28
FR2520741A1 (fr)	1983-08-05
NZ203144A (en)	1985-12-13
AT391865B (de)	1990-12-10
IT1197565B (it)	1988-12-06
PT76175A (en)	1983-03-01
SE8300535L (sv)	1983-08-04
GB2116171B (en)	1986-04-03
ZA83733B (en)	1984-09-26
DE3302814C2 (fr)	1992-06-25
FI830297A0 (fi)	1983-01-27
CY1485A (en)	1989-12-08
MY8700167A (en)	1987-12-31
US4474141A (en)	1984-10-02
DK160043C (da)	1991-06-17
HK47789A (en)	1989-06-23
ES519477A0 (es)	1984-03-16
AU569838B2 (en)	1988-02-25
DK40883D0 (da)	1983-02-01
PT76175B (en)	1986-01-15
ES8403473A1 (es)	1984-03-16
ATA34983A (de)	1990-06-15
JPH0446275B2 (fr)	1992-07-29
IT8347666A0 (it)	1983-02-03
IE55073B1 (en)	1990-05-23
DK160043B (da)	1991-01-21
IE830202L (en)	1983-08-03
KE3877A (en)	1989-07-21
CA1193271A (fr)	1985-09-10
FI830297L (fi)	1983-08-04
HU190886B (en)	1986-12-28
SG16289G (en)	1989-07-07
NL8300350A (nl)	1983-09-01
JPS58146580A (ja)	1983-09-01
DK40883A (da)	1983-08-04
FI80689B (fi)	1990-03-30
US4737516A (en)	1988-04-12
FI80689C (fi)	1990-07-10
FR2520741B1 (fr)	1986-03-21

Publication	Publication Date	Title
FR2531083B1 (fr)	1986-11-28	Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments
FR2551064B1 (fr)	1989-12-01	Nouveaux esters et amides aromatiques, leur preparation et leur utilisation comme medicaments
FR2535321B1 (fr)	1985-10-18	Nouveaux derives de l'ethanol, leur preparation et leur utilisation comme fongicides
FR2542000B1 (fr)	1988-02-19	Nouveaux derives de l'ethanol, leur preparation et leur utilisation comme fongicides
FR2615191B1 (fr)	1991-01-11	Nouveaux benzo(b)pyrannes et pyrannopyridines, leur preparation et leur utilisation comme medicaments
FR2501199B1 (fr)	1986-02-21	Nouveaux polypeptides, leur preparation et leur application comme medicaments
FR2482611B1 (fr)	1986-03-07	Nouveaux polysaccharides sulfates, procedes pour leur preparation et leur utilisation comme medicaments
PT76528B (fr)	1985-12-09	Nouveaux derives d'arene et d'heteroarenecarboxamides et leur utilisation comme medicaments
FR2511003B1 (fr)	1986-12-05	Alacaloides ergopeptidiques, leur preparation et leur utilisation comme medicaments
FR2531962B1 (fr)	1986-11-14	Nouveaux derives de la desoxyuridine, leur preparation et leur utilisation comme medicaments
FR2559150B1 (fr)	1986-06-27	Nouveaux derives du cyano-2 benzimidazole, leur preparation et leur utilisation comme fongicides
FR2551438B1 (fr)	1989-02-17	Nouveaux derives de l'ethanol, leur preparation et leur utilisation comme fongicides
FR2495168B1 (fr)	1986-05-16	Nouveaux alkylpolyoxyalkylene-carboxylates, leur preparation et leur utilisation comme agents tensio-actifs
FR2496103B1 (fr)	1986-04-18	Nouveaux derives du benzopyranne et du benzothiopyranne, leur preparation et leur application comme medicaments
FR2540112B1 (fr)	1986-08-29	Nouveaux derives de la benzo(g)quinoleine, leur preparation et leur utilisation comme medicaments
BE896590A (fr)	1983-10-28	Nouveaux azepino-indoles leur preparation et leur utilisation comme medicaments
FR2527608B1 (fr)	1986-10-10	Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments
BE883080A (fr)	1980-11-03	Nouvelles pyrazinobenzodiazepines, leur preparation et leur application comme medicaments
FR2520741B1 (fr)	1986-03-21	Nouveaux derives du benzothiophene, leur preparation et leur utilisation comme medicaments
FR2527206B1 (fr)	1986-12-05	Nouveaux derives de la 2(1h)-pyridinone, leur preparation et leur utilisation comme medicaments
FR2549058B1 (fr)	1988-02-19	Nouveaux derives de la 1,4-dihydropyridine, leur preparation et leur utilisation comme medicaments
FR2532308B1 (fr)	1987-09-11	Nouveaux polypeptides, leur preparation et leur application comme medicaments
BE874683A (fr)	1979-09-10	Nouveaux derives bicyclo-octaniques leur preparation et leur utilisation comme medicaments
FR2528431B1 (fr)	1986-01-10	Nouveaux derives de la 1,4-dihydropyridine, leur preparation et leur utilisation comme medicaments
FR2530634B1 (fr)	1986-11-14	Derives du carbapeneme, leur preparation et leur utilisation comme medicaments

Legal Events

Date	Code	Title	Description
1995-07-31	RE	Patent lapsed	Owner name: SANDOZ S.A. Effective date: 19950131

Date

Code

Title

Description

1995-07-31

Patent lapsed

Owner name: SANDOZ S.A.

Effective date: 19950131