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ATA34983A - Verfahren zur herstellung neuer benzothiophenderivate - Google Patents

Verfahren zur herstellung neuer benzothiophenderivate

Info

Publication number
ATA34983A
ATA34983A AT83349A AT34983A ATA34983A AT A34983 A ATA34983 A AT A34983A AT 83349 A AT83349 A AT 83349A AT 34983 A AT34983 A AT 34983A AT A34983 A ATA34983 A AT A34983A
Authority
AT
Austria
Prior art keywords
producing new
benzothiophene derivatives
new benzothiophene
derivatives
producing
Prior art date
Application number
AT83349A
Other languages
English (en)
Other versions
AT391865B (de
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of ATA34983A publication Critical patent/ATA34983A/de
Application granted granted Critical
Publication of AT391865B publication Critical patent/AT391865B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/40—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/58—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heat-Exchange Devices With Radiators And Conduit Assemblies (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Refuge Islands, Traffic Blockers, Or Guard Fence (AREA)
AT0034983A 1982-02-03 1983-02-02 Verfahren zur herstellung neuer benzothiophenderivate AT391865B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH656/82A CH653028A5 (de) 1982-02-03 1982-02-03 Benzthiophenallylamin-verbindungen und verfahren zu ihrer herstellung.

Publications (2)

Publication Number Publication Date
ATA34983A true ATA34983A (de) 1990-06-15
AT391865B AT391865B (de) 1990-12-10

Family

ID=4192086

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0034983A AT391865B (de) 1982-02-03 1983-02-02 Verfahren zur herstellung neuer benzothiophenderivate

Country Status (28)

Country Link
US (2) US4474141A (de)
JP (1) JPS58146580A (de)
AT (1) AT391865B (de)
AU (1) AU569838B2 (de)
BE (1) BE895751A (de)
CA (1) CA1193271A (de)
CH (1) CH653028A5 (de)
CY (1) CY1485A (de)
DE (1) DE3302814A1 (de)
DK (1) DK160043C (de)
ES (1) ES8403473A1 (de)
FI (1) FI80689C (de)
FR (1) FR2520741B1 (de)
GB (1) GB2116171B (de)
HK (1) HK47789A (de)
HU (1) HU190886B (de)
IE (1) IE55073B1 (de)
IL (1) IL67813A0 (de)
IT (1) IT1197565B (de)
KE (1) KE3877A (de)
MY (1) MY8700167A (de)
NL (1) NL8300350A (de)
NZ (1) NZ203144A (de)
PH (1) PH22625A (de)
PT (1) PT76175B (de)
SE (1) SE455095B (de)
SG (1) SG16289G (de)
ZA (1) ZA83733B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH672311A5 (de) * 1985-09-14 1989-11-15 Sandoz Ag
EP0404721A3 (de) * 1989-06-20 1991-12-27 Ciba-Geigy Ag Mikrobizide Mittel
CA2038633A1 (en) * 1990-03-20 1991-09-21 Yoshimi Tsuchiya Substituted amine derivatives having anti-hyperlipemia activity
FR2695930B1 (fr) * 1992-09-22 1994-12-23 Sanofi Elf Dérivé du 2-éthyl benzo[b]thiophène, son procédé de préparation et son utilisation comme intermédiaire de synthèse.
JP4759500B2 (ja) * 2001-02-22 2011-08-31 帝人株式会社 ベンゾ［ｂ］チオフェン誘導体、およびその製造方法
KR20080058435A (ko) * 2005-10-27 2008-06-25 데이진 화-마 가부시키가이샤 벤조[ｂ]티오펜 유도체 및 그 제조 방법
CN102898314B (zh) * 2012-11-13 2014-09-03 山东铂源药业有限公司 一种盐酸特比萘芬的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1250019B (de) * 1963-07-19
CH442353A (de) * 1964-04-16 1967-08-31 Sandoz Ag Verfahren zur Herstellung von neuen Benzothiophen-Derivaten
US3930537A (en) * 1974-05-06 1976-01-06 The United States Of America As Represented By The United States Energy Research And Development Administration Heat exchanger
EP0000896B1 (de) * 1977-08-19 1982-10-13 Sandoz Ag Propenyl-amine, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen, die sie enthalten
CY1410A (en) * 1979-08-22 1988-04-22 Sandoz Ag Propenylamines, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals

Also Published As

Publication number Publication date
IL67813A0 (en) 1983-06-15
DE3302814A1 (de) 1983-08-11
GB8302573D0 (en) 1983-03-02
SE455095B (sv) 1988-06-20
CH653028A5 (de) 1985-12-13
GB2116171A (en) 1983-09-21
SE8300535D0 (sv) 1983-02-01
AU1089783A (en) 1983-08-11
PH22625A (en) 1988-10-28
FR2520741A1 (fr) 1983-08-05
NZ203144A (en) 1985-12-13
AT391865B (de) 1990-12-10
IT1197565B (it) 1988-12-06
PT76175A (en) 1983-03-01
SE8300535L (sv) 1983-08-04
GB2116171B (en) 1986-04-03
ZA83733B (en) 1984-09-26
DE3302814C2 (de) 1992-06-25
FI830297A0 (fi) 1983-01-27
CY1485A (en) 1989-12-08
MY8700167A (en) 1987-12-31
US4474141A (en) 1984-10-02
DK160043C (da) 1991-06-17
HK47789A (en) 1989-06-23
ES519477A0 (es) 1984-03-16
AU569838B2 (en) 1988-02-25
DK40883D0 (da) 1983-02-01
PT76175B (en) 1986-01-15
BE895751A (fr) 1983-08-01
ES8403473A1 (es) 1984-03-16
JPH0446275B2 (de) 1992-07-29
IT8347666A0 (it) 1983-02-03
IE55073B1 (en) 1990-05-23
DK160043B (da) 1991-01-21
IE830202L (en) 1983-08-03
KE3877A (en) 1989-07-21
CA1193271A (en) 1985-09-10
FI830297L (fi) 1983-08-04
HU190886B (en) 1986-12-28
SG16289G (en) 1989-07-07
NL8300350A (nl) 1983-09-01
JPS58146580A (ja) 1983-09-01
DK40883A (da) 1983-08-04
FI80689B (fi) 1990-03-30
US4737516A (en) 1988-04-12
FI80689C (fi) 1990-07-10
FR2520741B1 (fr) 1986-03-21

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Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee
ELJ Ceased due to non-payment of the annual fee