[go: up one dir, main page]

AU741584B2 - Analogs of parathyroid hormone - Google Patents

Analogs of parathyroid hormone Download PDF

Info

Publication number
AU741584B2
AU741584B2 AU55199/98A AU5519998A AU741584B2 AU 741584 B2 AU741584 B2 AU 741584B2 AU 55199/98 A AU55199/98 A AU 55199/98A AU 5519998 A AU5519998 A AU 5519998A AU 741584 B2 AU741584 B2 AU 741584B2
Authority
AU
Australia
Prior art keywords
leu
aib
cha
lys
ahc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU55199/98A
Other languages
English (en)
Other versions
AU5519998A (en
Inventor
Zheng Xin Dong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Pharma SAS
Original Assignee
Ipsen Bioscience Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/779,768 external-priority patent/US5969095A/en
Application filed by Ipsen Bioscience Inc filed Critical Ipsen Bioscience Inc
Publication of AU5519998A publication Critical patent/AU5519998A/en
Application granted granted Critical
Publication of AU741584B2 publication Critical patent/AU741584B2/en
Assigned to SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) reassignment SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) Alteration of Name(s) in Register under S187 Assignors: BIOMEASURE INCORPORATED
Assigned to IPSEN PHARMA S.A.S reassignment IPSEN PHARMA S.A.S Request to Amend Deed and Register Assignors: SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.)
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AU55199/98A 1997-01-07 1997-12-08 Analogs of parathyroid hormone Ceased AU741584B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US08/779,768 US5969095A (en) 1995-07-13 1997-01-07 Analogs of parathyroid hormone
US08/779768 1997-01-07
US08/813534 1997-03-07
US08/813,534 US5955574A (en) 1995-07-13 1997-03-07 Analogs of parathyroid hormone
PCT/US1997/022498 WO1998030590A2 (en) 1997-01-07 1997-12-08 Analogs of parathyroid hormone

Publications (2)

Publication Number Publication Date
AU5519998A AU5519998A (en) 1998-08-03
AU741584B2 true AU741584B2 (en) 2001-12-06

Family

ID=27119618

Family Applications (1)

Application Number Title Priority Date Filing Date
AU55199/98A Ceased AU741584B2 (en) 1997-01-07 1997-12-08 Analogs of parathyroid hormone

Country Status (24)

Country Link
US (1) US5955574A (cs)
EP (3) EP1645566B1 (cs)
JP (1) JP3963482B2 (cs)
KR (2) KR100699422B1 (cs)
CN (1) CN1137898C (cs)
AR (3) AR011517A1 (cs)
AT (2) ATE471342T1 (cs)
AU (1) AU741584B2 (cs)
BR (1) BR9714200A (cs)
CA (1) CA2276614C (cs)
CZ (2) CZ298937B6 (cs)
DE (2) DE69739912D1 (cs)
DK (2) DK1645566T3 (cs)
ES (2) ES2258286T3 (cs)
HK (1) HK1026215A1 (cs)
HU (1) HUP9904596A3 (cs)
IL (1) IL130794A0 (cs)
NO (1) NO993341L (cs)
NZ (1) NZ336610A (cs)
PL (1) PL191898B1 (cs)
PT (2) PT948541E (cs)
RU (1) RU2198182C2 (cs)
SI (2) SI0948541T1 (cs)
WO (1) WO1998030590A2 (cs)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6544949B1 (en) * 1995-07-13 2003-04-08 Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. Analogs of parathyroid hormone
US7410948B2 (en) * 1995-07-13 2008-08-12 Societe De Conseils De Recherches Et D'applications Scientifiques, Sas Analogs of parathyroid hormone
ZA988030B (en) * 1997-09-09 1999-03-09 Hoffmann La Roche Fracture healing using pthrp analogs
WO1999057139A2 (en) * 1998-05-05 1999-11-11 Societe De Conseils De Recherches Et D'applications Scientifiques Sas Pth2 receptor selective compounds
ES2335827T3 (es) * 1998-07-20 2010-04-05 Ipsen Pharma Analogos peptidos de pacap.
US6660843B1 (en) † 1998-10-23 2003-12-09 Amgen Inc. Modified peptides as therapeutic agents
AU2000265051A1 (en) 2000-02-18 2001-08-27 Dabur Research Foundation Vasoactive intestinal peptide analogs
US20050124537A1 (en) * 2000-04-27 2005-06-09 Amgen Inc. Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein
US6756480B2 (en) * 2000-04-27 2004-06-29 Amgen Inc. Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein
KR20090116836A (ko) * 2001-06-01 2009-11-11 노파르티스 아게 부갑상선 호르몬 및 칼시토닌의 경구 투여
AU2002339843B2 (en) 2001-07-23 2007-12-06 The General Hospital Corporation Conformationally constrained parathyroid hormone (PTH) analogs
KR20060056975A (ko) * 2003-08-06 2006-05-25 로디아 인코포레이티드 뼈 성장 촉진방법
WO2007059470A2 (en) 2005-11-10 2007-05-24 Board Of Control Of Michigan Technological University Black bear parathyroid hormone and methods of using black bear parathyroid hormone
USRE49444E1 (en) 2006-10-03 2023-03-07 Radius Health, Inc. Method of treating osteoporosis comprising administration of PTHrP analog
BRPI0722428A2 (pt) * 2006-10-03 2013-11-26 Radius Health Inc Uso de composição estável no armazenamento
US7803770B2 (en) 2006-10-03 2010-09-28 Radius Health, Inc. Method of treating osteoporosis comprising administration of PTHrP analog
EA014696B1 (ru) * 2006-10-13 2010-12-30 Эли Лилли Энд Компани Пэгилированный паратиреоидный гормон в качестве модулятора рецептора паратиреоидного гормона и его применение
CA3017668C (en) 2007-08-01 2021-11-09 The General Hospital Corporation Screening methods using g-protein coupled receptors and related compositions
US8563513B2 (en) 2009-03-27 2013-10-22 Van Andel Research Institute Parathyroid hormone peptides and parathyroid hormone-related protein peptides and methods of use
AU2009356227A1 (en) 2009-12-07 2012-06-21 Michigan Technological University Black bear parathyroid hormone and methods of using black bear parathyroid hormone
MX342898B (es) 2010-05-12 2016-10-18 Radius Health Inc * Regimen terapéutico de la sal de diclorhidrato del (r) -6-(2-(etil (4-2(etilamino) etil) bencil) amino)-4-metoxifenil)-5, 6,7,8-tetrahidronaftaleno-2-ol.
KR101900078B1 (ko) 2010-05-13 2018-09-18 더 제너럴 하스피탈 코포레이션 부갑상선 호르몬 아날로그 및 그의 용도
AU2011312490B2 (en) 2010-09-28 2015-06-25 Radius Pharmaceuticals, Inc. Selective androgen receptor modulators
CN108135177B (zh) 2015-04-29 2021-06-01 雷迪厄斯制药公司 用于治疗癌症的方法
WO2017007777A2 (en) * 2015-07-06 2017-01-12 Zhengxin Dong NOVEL FORMULATIONS OF PTHrP ANALOGUE
AU2017281038B2 (en) 2016-06-22 2021-09-09 Ellipses Pharma Ltd AR+ breast cancer treatment methods
CN110191707A (zh) 2017-01-05 2019-08-30 雷迪厄斯制药公司 Rad1901-2hcl的多晶型形式
US10996208B2 (en) 2017-04-28 2021-05-04 Radius Health, Inc. Abaloparatide formulations and methods of testing, storing, modifying, and using same
SG11202013177WA (en) 2018-07-04 2021-01-28 Radius Pharmaceuticals Inc Polymorphic forms of rad 1901-2hcl

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994001460A1 (en) * 1992-07-14 1994-01-20 Syntex (U.S.A.) Inc. Analogs of pth and pthrp, their synthesis and use for the treatment of osteoporosis
GB2269176A (en) * 1992-07-15 1994-02-02 Sandoz Ltd Parathyroid hormone variants
AU6483496A (en) * 1995-07-13 1997-02-10 Ipsen Pharma S.A.S. Analogs of parathyroid hormone

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
IE52535B1 (en) 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
FR2550204B1 (fr) * 1983-08-05 1987-11-13 Toyo Jozo Kk Derives peptidiques de (nle8,nle1b, tyr34)-h-pth
EP0293158A3 (en) * 1987-05-26 1990-05-09 Merck & Co. Inc. Parathyroid hormone antagonists
US5457047A (en) * 1989-02-23 1995-10-10 Gesellschaft Fur Biotechnologische Forschung Mbh (Gbf) DNA Sequences coding for PTH variants, PTH variants, expression vector, bacterial host, use and therapeutic composition
CA2040264A1 (en) * 1990-04-12 1991-10-13 Tatsuhiko Kanmera Parathyroid hormone antagonists
JPH0532696A (ja) * 1990-09-28 1993-02-09 Takeda Chem Ind Ltd 副甲状腺ホルモン誘導体
WO1993006846A1 (en) * 1991-10-10 1993-04-15 Pang Peter K T Parathyroid hormone analogues and use in osteoporosis treatment
US5434246A (en) * 1992-03-19 1995-07-18 Takeda Chemical Industries, Ltd. Parathyroid hormone derivatives
CA2098639A1 (en) * 1992-06-19 1993-12-20 K. Anne Kronis Bone stimulating, non-vasoactive parathyroid hormone variants
US5821225A (en) * 1992-07-14 1998-10-13 Syntex (U.S.A.) Inc. Method for the treatment of corticosteroid induced osteopenia comprising administration of modified PTH or PTHrp
SK74495A3 (en) 1993-01-06 1997-01-08 Kinerton Ltd Ionic molecular conjugates of biodegradable polyesters with bioactive polypeptides and a method of preparation thereof
CN1070500C (zh) * 1993-07-13 2001-09-05 森德克斯(美国)股份有限公司 甲状旁腺激素类似物和甲状旁腺激素相关肽：合成和治疗骨质疏松症的用途
AU4472896A (en) * 1994-12-19 1996-07-10 Beth Israel Hospital Association, The Continuous low-dose administration of parathyroid hormone or its agonist
CA2178894A1 (en) * 1995-06-15 1996-12-16 Tsunehiko Fukuda Parathyroid hormone derivatives and their use

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994001460A1 (en) * 1992-07-14 1994-01-20 Syntex (U.S.A.) Inc. Analogs of pth and pthrp, their synthesis and use for the treatment of osteoporosis
GB2269176A (en) * 1992-07-15 1994-02-02 Sandoz Ltd Parathyroid hormone variants
AU6483496A (en) * 1995-07-13 1997-02-10 Ipsen Pharma S.A.S. Analogs of parathyroid hormone

Also Published As

Publication number Publication date
EP1645566A3 (en) 2006-10-11
HUP9904596A1 (hu) 2000-06-28
CN1137898C (zh) 2004-02-11
SI0948541T1 (sl) 2006-06-30
CA2276614A1 (en) 1998-07-16
CN1254347A (zh) 2000-05-24
KR20060030006A (ko) 2006-04-07
ES2347154T3 (es) 2010-10-26
CZ239899A3 (cs) 2000-01-12
WO1998030590A9 (en) 1999-08-19
HK1026215A1 (en) 2000-12-08
ES2258286T3 (es) 2006-08-16
AR011517A1 (es) 2000-08-30
NZ336610A (en) 2001-07-27
EP1645566A2 (en) 2006-04-12
JP2001508439A (ja) 2001-06-26
EP2206725A1 (en) 2010-07-14
JP3963482B2 (ja) 2007-08-22
ATE471342T1 (de) 2010-07-15
RU2198182C2 (ru) 2003-02-10
DE69739912D1 (de) 2010-07-29
NO993341L (no) 1999-09-06
PT948541E (pt) 2006-07-31
EP0948541B1 (en) 2006-03-29
AU5519998A (en) 1998-08-03
KR20000069952A (ko) 2000-11-25
HUP9904596A3 (en) 2000-07-28
AR038552A2 (es) 2005-01-19
KR100699422B1 (ko) 2007-03-28
BR9714200A (pt) 2000-03-28
AR051906A2 (es) 2007-02-14
WO1998030590A3 (en) 1998-12-10
CZ301497B6 (cs) 2010-03-24
DK1645566T3 (da) 2010-09-27
CZ298937B6 (cs) 2008-03-19
WO1998030590A2 (en) 1998-07-16
EP0948541A2 (en) 1999-10-13
CA2276614C (en) 2002-06-11
SI1645566T1 (sl) 2010-11-30
DE69735603T2 (de) 2006-11-30
KR100497709B1 (ko) 2005-06-23
IL130794A0 (en) 2001-01-28
NO993341D0 (no) 1999-07-06
PL191898B1 (pl) 2006-07-31
ATE321784T1 (de) 2006-04-15
US5955574A (en) 1999-09-21
DE69735603D1 (de) 2006-05-18
PT1645566E (pt) 2010-08-31
EP1645566B1 (en) 2010-06-16
DK0948541T3 (da) 2006-07-17
PL334438A1 (en) 2000-02-28

Similar Documents

Publication Publication Date Title
AU741584B2 (en) Analogs of parathyroid hormone
US5723577A (en) Analogs of parathyroid hormone
USRE40850E1 (en) Analogs of parathyroid hormone
US7410948B2 (en) Analogs of parathyroid hormone
US5969095A (en) Analogs of parathyroid hormone
CA2226177C (en) Analogs of parathyroid hormone
MXPA99006387A (en) Analogs of parathyroid hormone
PL191239B1 (pl) Peptydy, analogi hormonu przytarczyc

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
PC Assignment registered

Owner name: SOCIETE DE CONSEILS DE RECHERCHES ET D APPLICATION

Free format text: FORMER OWNER WAS: BIOMEASURE INCORPORATED