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ATE405647T1 - Rekombinantes gelatin in impstoffen - Google Patents

Rekombinantes gelatin in impstoffen

Info

Publication number
ATE405647T1
ATE405647T1 AT00978469T AT00978469T ATE405647T1 AT E405647 T1 ATE405647 T1 AT E405647T1 AT 00978469 T AT00978469 T AT 00978469T AT 00978469 T AT00978469 T AT 00978469T AT E405647 T1 ATE405647 T1 AT E405647T1
Authority
AT
Austria
Prior art keywords
vaccines
recombinant gelatin
recombinant
gelatin
compositions
Prior art date
Application number
AT00978469T
Other languages
English (en)
Inventor
Robert Chang
Kari Kivirikko
Thomas Neff
David Olsen
James Polarek
Original Assignee
Fibrogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fibrogen Inc filed Critical Fibrogen Inc
Application granted granted Critical
Publication of ATE405647T1 publication Critical patent/ATE405647T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • A23L29/275Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of animal origin, e.g. chitin
    • A23L29/281Proteins, e.g. gelatin or collagen
    • A23L29/284Gelatin; Collagen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08HDERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00Macromolecular products derived from proteins
    • C08H1/06Macromolecular products derived from proteins derived from horn, hoofs, hair, skin or leather
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00Compositions of proteins; Compositions of derivatives thereof
    • C08L89/04Products derived from waste materials, e.g. horn, hoof or hair
    • C08L89/06Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin, e.g. gelatin
    • GPHYSICS
    • G03PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03CPHOTOSENSITIVE MATERIALS FOR PHOTOGRAPHIC PURPOSES; PHOTOGRAPHIC PROCESSES, e.g. CINE, X-RAY, COLOUR, STEREO-PHOTOGRAPHIC PROCESSES; AUXILIARY PROCESSES IN PHOTOGRAPHY
    • G03C1/00Photosensitive materials
    • G03C1/005Silver halide emulsions; Preparation thereof; Physical treatment thereof; Incorporation of additives therein
    • G03C1/04Silver halide emulsions; Preparation thereof; Physical treatment thereof; Incorporation of additives therein with macromolecular additives; with layer-forming substances
    • G03C1/047Proteins, e.g. gelatine derivatives; Hydrolysis or extraction products of proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/86Products or compounds obtained by genetic engineering
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Polymers & Plastics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Materials Engineering (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Birds (AREA)
  • Inorganic Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Dispersion Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
AT00978469T 1999-11-12 2000-11-10 Rekombinantes gelatin in impstoffen ATE405647T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16511499P 1999-11-12 1999-11-12
US20443700P 2000-05-15 2000-05-15

Publications (1)

Publication Number Publication Date
ATE405647T1 true ATE405647T1 (de) 2008-09-15

Family

ID=26861120

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00978469T ATE405647T1 (de) 1999-11-12 2000-11-10 Rekombinantes gelatin in impstoffen

Country Status (16)

Country Link
US (3) US20030064074A1 (de)
EP (4) EP1232181B1 (de)
JP (2) JP4597454B2 (de)
KR (1) KR20020059719A (de)
CN (1) CN1309737C (de)
AT (1) ATE405647T1 (de)
AU (2) AU1591701A (de)
BR (1) BR0015508A (de)
CA (2) CA2390995A1 (de)
DE (1) DE60040012D1 (de)
ES (1) ES2315244T3 (de)
HK (2) HK1046004B (de)
IL (2) IL149459A0 (de)
MX (1) MXPA02004666A (de)
RU (1) RU2002112751A (de)
WO (2) WO2001034801A2 (de)

Families Citing this family (134)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6992172B1 (en) * 1999-11-12 2006-01-31 Fibrogen, Inc. Recombinant gelatins
WO2001034801A2 (en) * 1999-11-12 2001-05-17 Fibrogen, Inc. Recombinant gelatin in vaccines
EP1238675A1 (de) * 2001-03-06 2002-09-11 Fuji Photo Film B.V. Rekombinante gelatineartige Proteine zur Verwendung als Plasmaexpander
WO2003087343A1 (en) * 2002-04-11 2003-10-23 Fibrogen, Inc. Production of stable collagens
JP4226846B2 (ja) * 2002-06-07 2009-02-18 キャタレント・ジャパン株式会社 口腔内で崩壊可能なソフトカプセル剤
EP1398324A1 (de) * 2002-09-11 2004-03-17 Fuji Photo Film B.V. Gelatin-artige Proteine als Plasma-Expander und als Plasmaersatz geeignete Verbindungen
US7115374B2 (en) 2002-10-16 2006-10-03 Gen-Probe Incorporated Compositions and methods for detecting West Nile virus
US7927840B2 (en) 2006-09-11 2011-04-19 Gen Probe Incorporated Method for detecting West Nile Virus nucleic acids in the 3′ non-coding region
AU2003301654A1 (en) * 2002-10-22 2004-05-13 Dainippon Pharmaceutical Co., Ltd. Stabilized composition
US20040254347A1 (en) * 2002-11-25 2004-12-16 Academia Sinica Method of cross-linking peptides
EP1576148B1 (de) 2002-12-23 2012-10-03 FUJIFILM Manufacturing Europe B.V. Verfahren zur beschichtung von zellkultur-trägern
CN100582244C (zh) 2003-02-25 2010-01-20 米迪缪尼有限公司 制备流感疫苗组合物的方法
US20060110406A1 (en) 2003-02-25 2006-05-25 Medimmune Vaccines, Inc. Refrigerator-temperature stable influenza vaccine compositions
ATE450548T1 (de) * 2003-03-28 2009-12-15 Fujifilm Mfg Europe Bv Rgd-angereicherte gelatineähnliche proteine mit verstärkter zellbindung
US7588774B2 (en) 2003-05-12 2009-09-15 Becton, Dickinson And Company Molecules enhancing dermal delivery of influenza vaccines
US20050123550A1 (en) * 2003-05-12 2005-06-09 Laurent Philippe E. Molecules enhancing dermal delivery of influenza vaccines
US8080642B2 (en) 2003-05-16 2011-12-20 Vical Incorporated Severe acute respiratory syndrome DNA compositions and methods of use
CN1218750C (zh) * 2003-06-06 2005-09-14 长春生物制品研究所 皮内注射用重组乙型肝炎卡介苗联合疫苗及制备方法
US20050058703A1 (en) * 2003-08-01 2005-03-17 Chang Robert C. Gelatin capsules
EP1651272A1 (de) * 2003-08-05 2006-05-03 Fuji Photo Film B.V. Verwendung von rekombinanter oder synthetischer gelatine als stabilisator in vakzinen
JP2007501224A (ja) * 2003-08-05 2007-01-25 フジ フォト フィルム ビー.ブイ. 安定剤としての組換え又は合成ゼラチン様タンパク質の、凍結乾燥医薬組成物中の使用
JP2007516968A (ja) * 2003-12-05 2007-06-28 ベクトン・ディキンソン・アンド・カンパニー 皮内コンパートメントにおける免疫応答を増強する方法、およびそれらの方法で有用な化合物
GB0403247D0 (en) * 2004-02-13 2004-03-17 Tillotts Pharma Ag A pharmaceutical composition
US7709256B2 (en) 2004-04-28 2010-05-04 Vaxdesign Corp. Disease model incorporation into an artificial immune system (AIS)
US8030070B2 (en) * 2004-04-28 2011-10-04 Sanofi Pasteur Vaxdesign Corp. Artificial lymphoid tissue equivalent
US8298824B2 (en) 2004-04-28 2012-10-30 Sanofi Pasteur Vaxdesign Corporation Methods of evaluating a test agent in a diseased cell model
US7785806B2 (en) 2004-04-28 2010-08-31 Vaxdesign Corporation Method for determining the immunogenicity of an antigen
US7855074B2 (en) 2004-04-28 2010-12-21 Vaxdesign Corp. Artificial immune system: methods for making and use
US7785883B2 (en) 2004-04-28 2010-08-31 Vax Design Corp. Automatable artificial immune system (AIS)
US8071373B2 (en) 2004-04-28 2011-12-06 Sanofi Pasteur Vaxdesign Corp. Co-culture lymphoid tissue equivalent (LTE) for an artificial immune system (AIS)
US7771999B2 (en) 2004-04-28 2010-08-10 Vaxdesign Corp. Disease model incorporation into an artificial immune system (AIS)
EP2769735B1 (de) * 2004-10-06 2017-04-19 MedImmune, LLC Kühlschranktemperaturstabile Grippeimpfstoff-zusammensetzungen
US7932353B2 (en) 2005-02-23 2011-04-26 Fujifilm Manufacturing Europe B.V. Non-glycosylated recombinant collagen-like polypeptides
WO2006107188A1 (en) 2005-04-06 2006-10-12 Fujifilm Manufacturing Europe B.V. A non-porous film for culturing cells
EP1726299A3 (de) * 2005-05-27 2007-04-18 StratoSphere Pharma AB Kerne und Mikrokapsel zur parenteralen Verabreichung sowie Verfahren zu deren Herstellung
US8017152B2 (en) 2005-05-27 2011-09-13 Stratosphere Pharma Ab Cores and microcapsules suitable for parenteral administration as well as process for their manufacture
DE102005054937A1 (de) * 2005-11-17 2007-05-24 Gelita Ag Angiogenese förderndes Substrat
DE102005054943A1 (de) * 2005-11-17 2007-05-24 Gelita Ag Verfahren zur Herstellung eines Hohlprofils auf Basis eines vernetzten, Gelatine enthaltenden Materials sowie Implantate in Form von Hohlprofilen
US8900865B2 (en) * 2005-12-14 2014-12-02 The Invention Science Fund I, Llc Blood brain barrier device
US7855062B2 (en) * 2005-12-14 2010-12-21 The Invention Science Fund I, Llc Bone cell delivery device
US9005944B2 (en) * 2005-12-14 2015-04-14 The Invention Science Fund I, Llc Bone cell delivery device
US9061075B2 (en) * 2005-12-14 2015-06-23 The Invention Science Fund I, Llc Bone delivery device
US8278094B2 (en) * 2005-12-14 2012-10-02 The Invention Science Fund I, Llc Bone semi-permeable device
US20110172826A1 (en) * 2005-12-14 2011-07-14 Amodei Dario G Device including altered microorganisms, and methods and systems of use
US20110183319A1 (en) * 2010-01-22 2011-07-28 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Compositions and methods for therapeutic delivery with microorganisms
US8734823B2 (en) * 2005-12-14 2014-05-27 The Invention Science Fund I, Llc Device including altered microorganisms, and methods and systems of use
US8682619B2 (en) * 2005-12-14 2014-03-25 The Invention Science Fund I, Llc Device including altered microorganisms, and methods and systems of use
JP2009521228A (ja) * 2005-12-21 2009-06-04 ヴァックスデザイン コーポレーション 単球の樹状細胞への分化を促進する多孔質膜デバイス
WO2007075979A2 (en) 2005-12-21 2007-07-05 Vaxdesign Corporation In vitro germinal centers
US20090238890A1 (en) * 2006-01-13 2009-09-24 Advanced Bionutrition Corporation Continuous spray-capture production system
EP2409714A1 (de) 2006-06-27 2012-01-25 Sanofi Pasteur VaxDesign Corporation Modelle für die Bewertung von Impfstoffen
EP1961411A1 (de) * 2007-02-21 2008-08-27 FUJIFILM Manufacturing Europe B.V. Zusammensetzung mit gesteuerter Freisetzung
EP1961414A1 (de) * 2007-02-21 2008-08-27 FUJIFILM Manufacturing Europe B.V. Rekombinante Gelatine enthaltende Zusammensetzung mit gesteuerter Freisetzung
WO2008103041A1 (en) 2007-02-21 2008-08-28 Fujifilm Manufacturing Europe B.V. Recombinant gelatins
WO2008133196A1 (ja) * 2007-04-19 2008-11-06 Fujifilm Corporation 再生医療用材料
DE102007024256A1 (de) * 2007-05-16 2008-11-20 Gelita Ag Gefäßstent
WO2009048661A1 (en) 2007-07-16 2009-04-16 Vaxdesign Corporation Artificial tissue constructs comprising alveolar cells and methods for using the same
US20100256075A1 (en) * 2007-09-14 2010-10-07 Arjo Lysander De Boer High Yield Secretion of Multimeric Recombinant Protein
WO2009075329A1 (ja) * 2007-12-11 2009-06-18 Fujifilm Corporation 分解性を調整したゼラチン組成物
WO2009082002A1 (ja) 2007-12-26 2009-07-02 The Kitasato Institute 安定に長期間保存できる日本脳炎ワクチンの製法方法及び該ワクチンの用途
WO2009086504A2 (en) * 2007-12-26 2009-07-09 Pinsky Mark A Collagen formulations for improved skin care
US20110256222A1 (en) 2008-04-10 2011-10-20 Arjo Lysander De Boer Recombinant Protein Enriched in a Heparin Binding Site and/or in a Heparan Sulfate Binding Site
ES2671068T3 (es) 2008-06-26 2018-06-04 Nobelpharma Co., Ltd. Agente para regenerar la membrana timpánica o el conducto auditivo externo
JP2011526510A (ja) * 2008-07-04 2011-10-13 フジフィルム・マニュファクチュアリング・ヨーロッパ・ベスローテン・フエンノートシャップ 医療用デバイスのコーティング方法
JP5237714B2 (ja) * 2008-07-29 2013-07-17 BioROIS株式会社 細胞輸送用担体及びそれを使用した細胞の輸送方法
WO2010038059A2 (en) * 2008-10-02 2010-04-08 Fujifilm Manufacturing Europe Bv Antimicrobial coating
CH700138B1 (it) 2008-12-19 2012-12-14 Ind Biomediche Insubri S A Matrice per impianto osseo e procedimento di preparazione della stessa.
US8551749B2 (en) 2009-04-23 2013-10-08 The Invention Science Fund I, Llc Device including bone cage and method for treatment of disease in a subject
JP2009173678A (ja) * 2009-04-30 2009-08-06 Nitta Gelatin Inc コラーゲンタンパク質からのエンドトキシン除去方法
US20120101040A1 (en) * 2009-05-07 2012-04-26 Fujifilm Corporation angiogenesis inducing agent comprising recombinant gelatin
CA2769011C (en) * 2009-07-28 2017-06-06 Xcellerex, Inc. Vaccine stabilizer
RU2012109419A (ru) * 2009-08-13 2013-09-20 Биоэнол С.Р.Л. Способ получения желатина, быстро растворяющегося в холодной воде, и продукт, полученный этим способом
WO2011027850A1 (ja) * 2009-09-04 2011-03-10 富士フイルム株式会社 ゼラチンを含む骨再生剤
EP2502939B1 (de) 2009-11-19 2016-01-27 Zhejiang University Unnatürliches collagen-artiges protein und seine verwendung
GB0921460D0 (en) 2009-12-08 2010-01-20 Fujifilm Mfg Europe Bv Anti-fibrotic hydrogel compositions
CN102858381B (zh) * 2010-03-01 2015-09-30 富士胶片株式会社 包括具有生物相容性的聚合物块和细胞的细胞构建体
US8486013B2 (en) * 2010-03-18 2013-07-16 Biotronik Ag Balloon catheter having coating
GB201008404D0 (en) 2010-05-20 2010-07-07 Fujifilm Mfg Europe Bv Hemostatic compositions
EP2407184A3 (de) * 2010-07-16 2014-10-29 Biotronik AG Abluminal beschichtete Wirkstoff-freisetzende Stents mit einer formschlüssigen Schutzschicht
GB201014388D0 (en) 2010-08-31 2010-10-13 Fujifilm Mfg Europe Bv Biocompatible compositions for tissue augmentation
MX386380B (es) * 2010-10-08 2025-03-18 Scherer Technologies Llc R P Forma de dosis de disolución rápida de vacuna oral que usa almidón.
GB201018044D0 (en) 2010-10-26 2010-12-08 Fujifilm Mfg Europe Bv Non-natural gelatin-like proteins with enhanced functionality
CN102020712B (zh) * 2010-11-11 2013-05-29 北京东方红航天生物技术股份有限公司 一种可用于疫苗稳定剂的类人胶原蛋白及其生产方法
JP2012149062A (ja) * 2010-12-29 2012-08-09 Bios Ikagaku Kenkyusho:Kk ヒトコラーゲン含有化粧料
US8728487B2 (en) * 2011-01-20 2014-05-20 Hua Wu Attenuated live vaccine for prevention of porcine reproductive and respiratory syndrome
JP5847418B2 (ja) * 2011-03-30 2016-01-20 富士フイルム株式会社 細胞接着性タンパク質
US9676837B2 (en) * 2011-08-03 2017-06-13 Shire Human Genetic Therapies, Inc. Collagen 7 and related methods
GB201119173D0 (en) 2011-11-07 2011-12-21 Fujifilm Mfg Europe Bv Porous tissue scaffolds
GB201119182D0 (en) 2011-11-07 2011-12-21 Fujifilm Mfg Europe Bv Porous tissue scaffolds
ES2556004T3 (es) * 2011-12-20 2016-01-12 Novozymes A/S Método para la eliminación de virus en una solución de proteína
EP2898087A2 (de) * 2012-09-18 2015-07-29 DSM IP Assets B.V. Verfahren zur herstellung von gelatine mit aspergillopepsin ii
JP5992529B2 (ja) * 2012-09-26 2016-09-14 富士フイルム株式会社 ポリペプチド、足場組成物、軟骨組織修復用組成物、軟骨細胞培養用組成物及びグリコサミノグリカン産生促進用組成物
CN103263688B (zh) * 2013-05-10 2014-07-30 华东师范大学 一种明胶组合物及其制备方法和应用
CN103725622A (zh) * 2013-12-19 2014-04-16 西安巨子生物基因技术股份有限公司 一种转基因毕赤酵母基因工程菌及其构建方法与应用
JP6346672B2 (ja) * 2014-10-22 2018-06-20 富士フイルム株式会社 マイクロキャリアの調整方法、マイクロキャリア及びその応用
US9526768B2 (en) 2014-11-13 2016-12-27 Jennifer Mai Compositions for the treatment of cancer
NL2013880B1 (en) * 2014-11-26 2016-10-11 Rousselot B V Gelatin purification.
CN105061589B (zh) * 2015-08-26 2018-02-27 华南理工大学 一种重组人ⅰ型胶原蛋白及其固定化发酵生产的方法
JP6802838B2 (ja) 2016-04-21 2020-12-23 富士フイルム株式会社 多孔質ゼラチンシートの製造方法、多孔質ゼラチンシートおよびその利用
NL2017219B1 (en) 2016-07-22 2018-01-30 Rousselot B V Low cross-linking gelatine
US11180541B2 (en) * 2017-09-28 2021-11-23 Geltor, Inc. Recombinant collagen and elastin molecules and uses thereof
CN107857812A (zh) * 2017-11-17 2018-03-30 杭州惠博士生物科技有限公司 一种同人源胶原蛋白氨基酸、基因序列及蛋白氨基酸的制备方法
EP3713953A4 (de) * 2017-11-22 2021-08-25 Geltor, Inc. Verfahren und systeme zur züchtung von kollagen
EP3489314A1 (de) * 2017-11-23 2019-05-29 Rousselot B.V. Verfahren zur herstellung von gelatinehydrolysat mit niedrigem endotoxingehalt
ES2920153T3 (es) * 2017-12-08 2022-08-01 Chenguang Biotech Group Co Ltd Polvo de microcápsulas de licopeno y método de preparación para el mismo
CN111902129A (zh) * 2018-03-08 2020-11-06 康特伦英国斯温顿捷迪斯有限公司 减少明胶中内毒素的方法
AU2019336940A1 (en) * 2018-09-06 2021-03-11 Bavarian Nordic A/S Storage improved poxvirus compositions
EP3867354A4 (de) * 2018-10-16 2022-07-27 Board of Regents, The University of Texas System Zusammensetzungen und verfahren zur herstellung von tumororganoiden
DE102019202606A1 (de) 2018-11-06 2020-05-07 Gelita Ag Rekombinante Herstellung eines Kollagenpeptidpräparates und dessen Verwendung
CN109503707A (zh) * 2018-11-22 2019-03-22 江西师范大学 一种提高鱼皮明胶品性的方法
CN109504665B (zh) * 2018-11-22 2022-08-23 江西师范大学 一种提高鱼鳞明胶品性的方法
DE102019207859A1 (de) * 2018-12-21 2020-06-25 Gelita Ag Synthetische und rekombinant hergestellte Kollagenpeptide mit biologischer Wirksamkeit
GB2596998B (en) * 2019-04-01 2023-10-04 Geltor Inc Topical formulations of recombinant collagens
CA3136691A1 (en) 2019-04-12 2020-10-15 Geltor, Inc. Recombinant elastin and production thereof
WO2021066049A1 (ja) * 2019-09-30 2021-04-08 Spiber株式会社 タンパク質接着剤、接合体及びその製造方法
DE102020210725A1 (de) 2019-10-31 2021-05-06 Gelita Ag Ernährungsphysiologisch optimiertes Kollagenpeptid
JPWO2021112254A1 (de) * 2019-12-06 2021-06-10
CN111011756A (zh) * 2019-12-26 2020-04-17 江西省壹加壹贸易有限公司 一种可食用的农副产品及禽蛋类载体广告宣传涂层及方法
DE102020205703A1 (de) 2020-05-06 2021-11-11 Gelita Ag Expression von Kollagenpeptid-Komponenten in prokaryotischen Systemen
WO2021229577A1 (en) 2020-05-12 2021-11-18 Collplant Ltd. Collagen as a delivery tool for metal-based anti-viral agents
CN113880940A (zh) * 2020-07-03 2022-01-04 江苏江山聚源生物技术有限公司 重组人源Ⅰ型胶原蛋白Ⅰα1x6、表达菌株及其应用
EP4288084A1 (de) * 2021-02-05 2023-12-13 Modern Meadow, Inc. Hautpflegezusammensetzungen und verfahren zur verwendung davon
DE102021202830A1 (de) 2021-03-23 2022-09-29 Gelita Ag Rekombinantes Typ II-Kollagen zur therapeutischen Verwendung
JPWO2023095781A1 (de) * 2021-11-24 2023-06-01
DE102021214899A1 (de) 2021-12-22 2023-06-22 Gelita Ag Typ I-Kollagenpeptid zur therapeutischen Verwendung
EP4202035A1 (de) 2021-12-22 2023-06-28 Gelita AG Verbesserte expression von peptiden
KR20240133713A (ko) * 2022-01-14 2024-09-04 캠브리움 게엠베하 신규 재조합 콜라겐 폴리펩티드 및 분자
CN114316029B (zh) * 2022-01-27 2023-06-27 西安巨子生物基因技术股份有限公司 透皮吸收性肽及通过该肽的重复构建的重组胶原蛋白
TWI856287B (zh) * 2022-02-11 2024-09-21 國立臺灣科技大學 可溶解感溫型的微載體、其製備方法及其使用方法
WO2023201027A1 (en) * 2022-04-14 2023-10-19 Omeat Inc. Systems and methods for protein recovery from cell culture media
CN114940712B (zh) * 2022-06-01 2023-12-26 山西锦波生物医药股份有限公司 一种生物合成人体结构性材料的制备方法
CN115960268B (zh) * 2022-12-30 2025-03-11 广州栋方生物科技股份有限公司 一种胶原蛋白-芋螺肽融合蛋白及其制备方法和应用
TW202446787A (zh) * 2023-05-17 2024-12-01 美商Htl生物科技創新股份有限公司 膠原蛋白生產程序
DE102023205346A1 (de) 2023-06-07 2024-12-12 Gelita Ag Verzehrbare Produkte mit rekombinant hergestelltem Kollagen

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US987292A (en) 1910-05-04 1911-03-21 William T Anderson Tire.
US4147772A (en) 1976-02-03 1979-04-03 Merck & Co., Inc. Vaccine stabilizer
US4215051A (en) 1979-08-29 1980-07-29 Standard Oil Company (Indiana) Formation, purification and recovery of phthalic anhydride
US4337242A (en) 1980-02-05 1982-06-29 Merck & Co., Inc. Vaccine stabilizer containing L-glutamic acid and L-arginine
US4338335A (en) 1980-02-05 1982-07-06 Merck & Co., Inc. Vaccine stabilizer containing L-glutamic acid and L-arginine
US4407956A (en) 1981-03-13 1983-10-04 The Regents Of The University Of California Cloned cauliflower mosaic virus DNA as a plant vehicle
CA1192510A (en) 1981-05-27 1985-08-27 Lawrence E. Pelcher Rna plant virus vector or portion thereof, a method of construction thereof, and a method of producing a gene derived product therefrom
NL8200523A (nl) 1982-02-11 1983-09-01 Univ Leiden Werkwijze voor het in vitro transformeren van planteprotoplasten met plasmide-dna.
US4536475A (en) 1982-10-05 1985-08-20 Phytogen Plant vector
US4736866A (en) 1984-06-22 1988-04-12 President And Fellows Of Harvard College Transgenic non-human mammals
US4855231A (en) 1984-10-30 1989-08-08 Phillips Petroleum Company Regulatory region for heterologous gene expression in yeast
US4945050A (en) 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
ZA859400B (en) 1984-12-10 1986-10-29 Monsanto Co Insertion of the bacillus thuringiensis crystal protein gene into plant-colonizing microorganisms and their use
AU590558B2 (en) 1985-04-30 1989-11-09 Monsanto Company Plant-colonizing microorganisms containing the toxin gene of b. thuringiensis as a chromosomal insertion
TR27832A (tr) 1987-04-29 1995-08-31 Monsanto Co Zararli ucucu hasarata mukavim bitkiler.
JPS63307827A (ja) 1987-06-08 1988-12-15 Kitasato Inst:The 安定化された生ウイルスワクチンおよびその製造法
US5464764A (en) 1989-08-22 1995-11-07 University Of Utah Research Foundation Positive-negative selection methods and vectors
US5614396A (en) 1990-06-14 1997-03-25 Baylor College Of Medicine Methods for the genetic modification of endogenous genes in animal cells by homologous recombination
US5731166A (en) 1990-09-05 1998-03-24 The Heart Research Institute Ltd. Recombinant production of chemotactic CP-10 polypeptides and therapeutic methods using them
US5593859A (en) 1991-10-23 1997-01-14 Thomas Jefferson University Synthesis of human procollagens and collagens in recombinant DNA systems
EP0625048B2 (de) * 1991-10-23 2005-10-26 Thomas Jefferson University Synthese von humanen prokollagenen und kollagenen in rekombinanten dna-systemen
FR2685347A1 (fr) * 1991-12-23 1993-06-25 Univ Pasteur Procede biotechnologique d'obtention et de production microbienne d'oligomeres peptidiques comme substituts de la gelatine.
US5593874A (en) 1992-03-19 1997-01-14 Monsanto Company Enhanced expression in plants
JPH06234659A (ja) * 1992-05-05 1994-08-23 Handai Biseibutsubiyou Kenkyukai 安定化生ワクチン
AU2088992A (en) 1992-05-05 1993-11-11 Research Foundation For Microbial Diseases Of Osaka University, The Stabilized live vaccine
US5981505A (en) * 1993-01-26 1999-11-09 The Trustees Of The University Of Pennsylvania Compositions and methods for delivery of genetic material
GB9316883D0 (en) 1993-08-13 1993-09-29 Univ Leeds Production of heterologous peptices
US5362865A (en) 1993-09-02 1994-11-08 Monsanto Company Enhanced expression in plants using non-translated leader sequences
US6713662B1 (en) * 1994-07-27 2004-03-30 Pharming Intellectual Property B.V. Production of collagen in the milk of transgenic mammals
US5710252A (en) * 1995-02-03 1998-01-20 Eastman Kodak Company Method for recombinant yeast expression and isolation of water-soluble collagen-type polypeptides
WO1997004123A1 (en) * 1995-07-19 1997-02-06 Gel Tech Group Inc. Collagen compound production in plants
JP2001510981A (ja) * 1995-11-13 2001-08-07 フィブロゲン,インコーポレーッテッド Ix型コラーゲンおよびキメラ
US5928922A (en) 1996-04-10 1999-07-27 Academy Of Finland α2 subunit of prolyl-4-hydroxylase, nucleic acid sequences encoding such subunit and methods for producing the same
WO1997038710A1 (en) * 1996-04-12 1997-10-23 Fibrogen, Inc. Synthesis of human procollagens and collagens in recombinant dna systems
US5824838A (en) 1996-05-09 1998-10-20 Cedars-Sinai Medical Center Transgenic mouse model for pituitary disorders associated with LIF overexpression and/or GH underexpression, and its use for testing therapeutic drugs for the conditions
US5821089A (en) * 1996-06-03 1998-10-13 Gruskin; Elliott A. Amino acid modified polypeptides
FR2757874B1 (fr) * 1996-12-17 2003-04-25 Biocem Collagenes recombinants et proteines derivees produits par les plantes, leurs procedes d'obtention et leurs utilisations
US6210683B1 (en) * 1997-09-05 2001-04-03 Merck & Co., Inc. Stabilizers containing recombinant human serum albumin for live virus vaccines
NL1007908C2 (nl) * 1997-12-24 1999-06-25 Fuji Photo Film Bv Zilverhalide-emulsies met recombinant collageen die geschikt zijn voor fotografische toediening alsmede de bereiding daarvan.
US6428978B1 (en) * 1998-05-08 2002-08-06 Cohesion Technologies, Inc. Methods for the production of gelatin and full-length triple helical collagen in recombinant cells
US6462013B1 (en) 1998-06-26 2002-10-08 National Starch And Chemical Investment Holding Corporation Isotropic liquid detergent comprising ethylenically unsaturated acid monomer-C1 to C24 chain transfer agent polymerization product
EP1014176B1 (de) 1998-12-23 2009-04-29 FUJIFILM Manufacturing Europe B.V. Silberhalogenidemulsionen, die rekombinante gelatineartige Proteine enthalten
US6992172B1 (en) * 1999-11-12 2006-01-31 Fibrogen, Inc. Recombinant gelatins
WO2001034801A2 (en) * 1999-11-12 2001-05-17 Fibrogen, Inc. Recombinant gelatin in vaccines
CN1285612C (zh) * 1999-11-12 2006-11-22 法布罗根股份有限公司 动物胶原和明胶
US6465207B1 (en) * 2000-11-03 2002-10-15 Cytologix Corporation Silver-based staining processes employing non-gelling gelatin

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