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ATE377414T1 - Mikropartikel, geeignet als kontrastmittel im ultraschall und zur wirkstoffgabe in den blutkreislauf - Google Patents

Mikropartikel, geeignet als kontrastmittel im ultraschall und zur wirkstoffgabe in den blutkreislauf

Info

Publication number
ATE377414T1
ATE377414T1 AT98918899T AT98918899T ATE377414T1 AT E377414 T1 ATE377414 T1 AT E377414T1 AT 98918899 T AT98918899 T AT 98918899T AT 98918899 T AT98918899 T AT 98918899T AT E377414 T1 ATE377414 T1 AT E377414T1
Authority
AT
Austria
Prior art keywords
microparticles
contrast agent
ultrasound
administration
active ingredients
Prior art date
Application number
AT98918899T
Other languages
English (en)
Inventor
Thomas Ottoboni
Robert Short
Ronald Yamamoto
Original Assignee
Point Biomedical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Point Biomedical Corp filed Critical Point Biomedical Corp
Application granted granted Critical
Publication of ATE377414T1 publication Critical patent/ATE377414T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0028—Disruption, e.g. by heat or ultrasounds, sonophysical or sonochemical activation, e.g. thermosensitive or heat-sensitive liposomes, disruption of calculi with a medicinal preparation and ultrasounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
    • A61K47/6925—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a microcapsule, nanocapsule, microbubble or nanobubble
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/225—Microparticles, microcapsules

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acoustics & Sound (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nanotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
AT98918899T 1997-04-30 1998-04-30 Mikropartikel, geeignet als kontrastmittel im ultraschall und zur wirkstoffgabe in den blutkreislauf ATE377414T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US84715397A 1997-04-30 1997-04-30

Publications (1)

Publication Number Publication Date
ATE377414T1 true ATE377414T1 (de) 2007-11-15

Family

ID=25299908

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98918899T ATE377414T1 (de) 1997-04-30 1998-04-30 Mikropartikel, geeignet als kontrastmittel im ultraschall und zur wirkstoffgabe in den blutkreislauf

Country Status (11)

Country Link
US (4) US6193951B1 (de)
EP (1) EP0979071B1 (de)
JP (1) JP2001527547A (de)
AT (1) ATE377414T1 (de)
AU (1) AU739919B2 (de)
CA (1) CA2289088C (de)
DE (2) DE19882362T1 (de)
ES (1) ES2296332T3 (de)
GB (1) GB2340040B (de)
NO (1) NO995313L (de)
WO (1) WO1998048783A1 (de)

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US20040086459A1 (en) 2004-05-06
ES2296332T3 (es) 2008-04-16
US20010012522A1 (en) 2001-08-09
CA2289088C (en) 2007-08-07
CA2289088A1 (en) 1998-11-05
NO995313L (no) 1999-12-29
DE69838669D1 (de) 2007-12-20
NO995313D0 (no) 1999-10-29
AU7173098A (en) 1998-11-24
JP2001527547A (ja) 2001-12-25
EP0979071A1 (de) 2000-02-16
EP0979071B1 (de) 2007-11-07
DE19882362T1 (de) 2000-05-18
GB2340040B (en) 2001-11-28
DE69838669T2 (de) 2008-10-30
EP0979071A4 (de) 2004-03-10
GB2340040A (en) 2000-02-16
US6193951B1 (en) 2001-02-27
WO1998048783A1 (en) 1998-11-05
AU739919B2 (en) 2001-10-25
GB9925661D0 (en) 1999-12-29
US20090081130A1 (en) 2009-03-26

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