PT659439E
(pt)
|
1993-12-24 |
2002-04-29 |
Merck Patent Gmbh |
Imunoconjugados
|
US7060808B1
(en)
*
|
1995-06-07 |
2006-06-13 |
Imclone Systems Incorporated |
Humanized anti-EGF receptor monoclonal antibody
|
AU4373197A
(en)
*
|
1996-09-19 |
1998-04-14 |
Diagnocure Inc. |
Recombinant single chain antibodies directed against the gp54 cancer marker, composition comprising same and use thereof
|
JP4215172B2
(ja)
*
|
1996-12-03 |
2009-01-28 |
アムジェン フレモント インク. |
複数のV▲下H▼およびV▲下κ▼領域を含むヒトIg遺伝子座を有するトランスジェニック哺乳動物、ならびにそれから産生される抗体
|
CN1276830A
(zh)
|
1997-09-02 |
2000-12-13 |
住友制药株式会社 |
抗乙型肝炎病毒核心蛋白的单链抗体及其基因和含有它们的乙型肝炎治疗药物
|
DE19744531A1
(de)
*
|
1997-10-09 |
1999-05-27 |
Klaus Dr Rer Nat Bosslet |
Bindemoleküle gegen Rezeptor-Ligand-Komplexe
|
CA2309679C
(en)
|
1997-11-17 |
2010-07-20 |
Peter Kufer |
Method of identifying binding site domains that retain the capacity of binding to an epitope
|
US20030224001A1
(en)
*
|
1998-03-19 |
2003-12-04 |
Goldstein Neil I. |
Antibody and antibody fragments for inhibiting the growth of tumors
|
ZA200007412B
(en)
*
|
1998-05-15 |
2002-03-12 |
Imclone Systems Inc |
Treatment of human tumors with radiation and inhibitors of growth factor receptor tyrosine kinases.
|
DE69901569T2
(de)
|
1998-08-28 |
2002-12-19 |
Genentech, Inc. |
Humane antikörper gegen faktor ix/ixa
|
IL146480A0
(en)
*
|
1999-05-14 |
2002-07-25 |
Imclone Systems Inc |
Treatment of refractory human tumors with epidermal growth factor receptor antagonists
|
US7144991B2
(en)
|
1999-06-07 |
2006-12-05 |
Aletheon Pharmaceuticals, Inc. |
Streptavidin expressed gene fusions and methods of use thereof
|
US7361338B2
(en)
*
|
1999-10-05 |
2008-04-22 |
Agensys, Inc. |
Methods to inhibit growth of prostate cancer cells
|
US6790631B1
(en)
*
|
1999-10-05 |
2004-09-14 |
Agensys, Inc. |
G protein-coupled receptor up-regulated in prostate cancer and uses thereof
|
CN1239701C
(zh)
*
|
2000-05-19 |
2006-02-01 |
梨树化学株式会社 |
抗表皮生长因子受体的人源化抗体
|
WO2001096401A1
(fr)
*
|
2000-06-14 |
2001-12-20 |
Medical & Biological Laboratories Co., Ltd. |
Procede de construction d'un anticorps scfv fusionne a une proteine fluorescente
|
US8697394B2
(en)
|
2000-06-28 |
2014-04-15 |
Glycofi, Inc. |
Production of modified glycoproteins having multiple antennary structures
|
US7598055B2
(en)
*
|
2000-06-28 |
2009-10-06 |
Glycofi, Inc. |
N-acetylglucosaminyltransferase III expression in lower eukaryotes
|
US7449308B2
(en)
*
|
2000-06-28 |
2008-11-11 |
Glycofi, Inc. |
Combinatorial DNA library for producing modified N-glycans in lower eukaryotes
|
EP2119793A1
(de)
*
|
2000-06-28 |
2009-11-18 |
Glycofi, Inc. |
Verfahren zur Herstellung modifizierter Glykoproteine
|
WO2002011677A2
(en)
*
|
2000-08-09 |
2002-02-14 |
Imclone Systems Incorporated |
Treatment of hyperproliferative diseases with epidermal growth factor receptor antagonists
|
US20030211106A1
(en)
*
|
2000-08-21 |
2003-11-13 |
Tornetta Mark A |
Anti-rank ligand monoclonal antibodies useful in treatment of rank ligand mediated disorders
|
US7829084B2
(en)
*
|
2001-01-17 |
2010-11-09 |
Trubion Pharmaceuticals, Inc. |
Binding constructs and methods for use thereof
|
EP2316951A1
(de)
*
|
2001-01-17 |
2011-05-04 |
Trubion Pharmaceuticals, Inc. |
Bindungsdomäne-Immunglobulin-Fusionsproteine
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
US20030133939A1
(en)
|
2001-01-17 |
2003-07-17 |
Genecraft, Inc. |
Binding domain-immunoglobulin fusion proteins
|
GB0103389D0
(en)
*
|
2001-02-12 |
2001-03-28 |
Novartis Ag |
Organic compounds
|
DE60232785D1
(de)
|
2001-03-14 |
2009-08-13 |
Myriad Genetics Inc |
Tsg101-gag-wechselwirkung und ihre verwendung
|
US20080008704A1
(en)
*
|
2001-03-16 |
2008-01-10 |
Mark Rubin |
Methods of treating colorectal cancer with anti-epidermal growth factor antibodies
|
DK1392359T4
(da)
|
2001-05-11 |
2013-06-10 |
Ludwig Inst For Cancer Res Ltd |
Specifikke bindingsproteiner og deres anvendelser.
|
US20100056762A1
(en)
|
2001-05-11 |
2010-03-04 |
Old Lloyd J |
Specific binding proteins and uses thereof
|
US20020193569A1
(en)
*
|
2001-06-04 |
2002-12-19 |
Idec Pharmaceuticals Corporation |
Bispecific fusion protein and method of use for enhancing effector cell killing of target cells
|
US7595378B2
(en)
|
2001-06-13 |
2009-09-29 |
Genmab A/S |
Human monoclonal antibodies to epidermal growth factor receptor (EGFR)
|
CZ200438A3
(cs)
*
|
2001-06-13 |
2004-06-16 |
Genmab A/S |
Název neuveden
|
EP2399586A1
(de)
|
2002-01-11 |
2011-12-28 |
Jefferies, Dr., Wilfred |
Verwendung von P97 als ein Enzymabgabesystem zur Abgabe therapeutischer lyosomaler Enzyme
|
US8034904B2
(en)
*
|
2002-06-14 |
2011-10-11 |
Immunogen Inc. |
Anti-IGF-I receptor antibody
|
ES2376165T3
(es)
|
2002-07-15 |
2012-03-09 |
F. Hoffmann-La Roche Ag |
Tratamiento del c�?ncer con el anticuerpo dirigido contra erbb2 rhumab 2c4.
|
JP5814494B2
(ja)
|
2002-11-12 |
2015-11-17 |
ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッドThe Brigham and Women’s Hospital, Inc. |
Staphylococcus感染に対する多糖類ワクチン
|
US20040147428A1
(en)
*
|
2002-11-15 |
2004-07-29 |
Pluenneke John D. |
Methods of treatment using an inhibitor of epidermal growth factor receptor
|
US7332299B2
(en)
|
2003-02-20 |
2008-02-19 |
Glycofi, Inc. |
Endomannosidases in the modification of glycoproteins in eukaryotes
|
EP1622941A2
(de)
*
|
2003-03-20 |
2006-02-08 |
ImClone Systems Incorporated |
Methode zur produktion von anti-egfr antikörpern
|
US7754209B2
(en)
|
2003-07-26 |
2010-07-13 |
Trubion Pharmaceuticals |
Binding constructs and methods for use thereof
|
EP1687338B1
(de)
|
2003-11-07 |
2010-10-20 |
Ablynx N.V. |
Camelidae schwere ketten antikörper vhhs gegen epidermalen wachstumfaktor rezeptor (egfr) und ihre verwendung
|
PT1735348E
(pt)
*
|
2004-03-19 |
2012-07-24 |
Imclone Llc |
Anticorpo anti-receptor do factor de crescimento humano
|
JP5080243B2
(ja)
*
|
2004-04-21 |
2012-11-21 |
ザ ブライハム アンド ウイメンズ ホスピタル, インコーポレイテッド |
ポリ−N−アセチルグルコサミン(PNAG/dPNAG)結合ペプチドおよびその使用方法
|
GB0410627D0
(en)
*
|
2004-05-12 |
2004-06-16 |
Scancell Ltd |
Specific binding members
|
EP2286844A3
(de)
|
2004-06-01 |
2012-08-22 |
Genentech, Inc. |
Antikörper-Arzneimittelkonjugate und Verfahren
|
US20100111856A1
(en)
|
2004-09-23 |
2010-05-06 |
Herman Gill |
Zirconium-radiolabeled, cysteine engineered antibody conjugates
|
ES2579805T3
(es)
|
2004-09-23 |
2016-08-16 |
Genentech, Inc. |
Anticuerpos y conjugados modificados por ingeniería genética con cisteína
|
CA2616395C
(en)
|
2005-07-25 |
2016-10-04 |
Trubion Pharmaceuticals |
B-cell reduction using cd37-specific and cd20-specific binding molecules
|
EA013878B1
(ru)
*
|
2005-12-06 |
2010-08-30 |
Домантис Лимитед |
Лиганды, имеющие специфичность связывания в отношении рецептора эпидермального фактора роста (egfr) и/или сосудистого эндотелиального фактора роста (vegf), и способы их применения
|
US7503217B2
(en)
*
|
2006-01-27 |
2009-03-17 |
Weatherford/Lamb, Inc. |
Sonar sand detection
|
AU2007222165A1
(en)
*
|
2006-03-06 |
2007-09-13 |
Agency For Science, Technology And Research |
Human embryonic stem cell methods and PODXL expression
|
EP3805269A1
(de)
|
2006-06-12 |
2021-04-14 |
Aptevo Research and Development LLC |
Einkettige, multivalente bindungsproteine mit effektorfunktion
|
EP2975057A1
(de)
|
2006-07-10 |
2016-01-20 |
Fujita Health University |
Neuer anti-cd73 antikörper
|
BRPI0720437A2
(pt)
|
2006-12-07 |
2014-01-07 |
Novartis Ag |
Anticorpos antafonísticos contra ephb3
|
US20100034816A1
(en)
*
|
2006-12-22 |
2010-02-11 |
Novelix Therapeutics Gmbh |
Treatment of Diabetes by at Least One Epidermal Growth Factor Receptor Specific Antibody or a Derivative Thereof
|
EP2126127B1
(de)
|
2007-01-25 |
2016-09-28 |
Dana-Farber Cancer Institute, Inc. |
Verwendung von anti-egfr-antikörpern bei der behandlung von durch egfr-mutanten vermittelten krankheiten
|
AU2008227123B2
(en)
|
2007-03-15 |
2014-03-27 |
Ludwig Institute For Cancer Research Ltd. |
Treatment method using EGFR antibodies and src inhibitors and related formulations
|
WO2008154927A1
(en)
*
|
2007-06-21 |
2008-12-24 |
Genmab A/S |
Novel methods for treating egfr-associated tumors
|
US9283276B2
(en)
|
2007-08-14 |
2016-03-15 |
Ludwig Institute For Cancer Research Ltd. |
Monoclonal antibody 175 targeting the EGF receptor and derivatives and uses thereof
|
AU2008302111B2
(en)
|
2007-09-21 |
2014-04-24 |
The Regents Of The University Of California |
Targeted interferon demonstrates potent apoptotic and anti-tumor activities
|
KR20110013391A
(ko)
*
|
2008-04-11 |
2011-02-09 |
이머전트 프로덕트 디벨롭먼트 시애틀, 엘엘씨 |
Cd37 면역치료제 및 이작용성 화학치료제와 이의 병용물
|
MX2010011955A
(es)
|
2008-04-29 |
2011-01-21 |
Abbott Lab |
Inmunoglobulinas de dominio variable doble y usos de las mismas.
|
EP2297209A4
(de)
|
2008-06-03 |
2012-08-01 |
Abbott Lab |
Dual-variable- domain-immunglobuline und ihre verwendungen
|
RU2010153578A
(ru)
|
2008-06-03 |
2012-07-20 |
Эбботт Лэборетриз (Us) |
Иммуноглобулины с двойными вариабельными доменами и их применение
|
MX2010014574A
(es)
|
2008-07-08 |
2011-04-27 |
Abbott Lab |
Inmunoglobulinas de dominio variable dual para prostaglandina e2 y usos de las mismas.
|
US8492364B2
(en)
|
2008-07-21 |
2013-07-23 |
The Brigham And Women's Hospital, Inc. |
Methods and compositions relating to synthetic β-1,6 glucosamine oligosaccharides
|
KR101108642B1
(ko)
*
|
2009-09-29 |
2012-02-09 |
주식회사 녹십자 |
표피 성장 인자 수용체에 특이적으로 결합하는 항체
|
AU2010306677B2
(en)
|
2009-10-15 |
2013-05-23 |
Abbvie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
UY32979A
(es)
|
2009-10-28 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
WO2011063346A1
(en)
*
|
2009-11-20 |
2011-05-26 |
Northshore University Health System Research Institute |
Targeting of the c-terminal segment of c. difficile toxin b for improved clinical diagnosis, prevention, and treatment
|
WO2011069104A2
(en)
|
2009-12-04 |
2011-06-09 |
Genentech, Inc. |
Multispecific antibodies, antibody analogs, compositions, and methods
|
CN102167743B
(zh)
*
|
2010-02-25 |
2014-05-14 |
上海百迈博制药有限公司 |
一种全人源抗egfr单克隆抗体、其制备方法及用途
|
WO2011133886A2
(en)
|
2010-04-23 |
2011-10-27 |
Genentech, Inc. |
Production of heteromultimeric proteins
|
WO2011152525A1
(ja)
*
|
2010-06-04 |
2011-12-08 |
東亞合成株式会社 |
抗体およびその利用
|
BR112013002578A2
(pt)
|
2010-08-03 |
2019-05-14 |
Abbvie Inc. |
imunoglobinas de domínio variável duplo e usos das mesmas
|
KR20130139884A
(ko)
|
2010-08-26 |
2013-12-23 |
애브비 인코포레이티드 |
이원 가변 도메인 면역글로불린 및 이의 용도
|
KR101273918B1
(ko)
*
|
2010-09-17 |
2013-06-13 |
강원대학교산학협력단 |
인간 항-상피세포성 성장인자수용체 Fab 항체 및 이를 포함하는 종양 치료용 약학 조성물
|
CN103298489A
(zh)
|
2010-10-29 |
2013-09-11 |
伊缪诺金公司 |
新型egfr结合分子及其免疫偶联物
|
JP5828902B2
(ja)
|
2010-10-29 |
2015-12-09 |
イミュノジェン, インコーポレイテッド |
非拮抗性egfr結合分子およびその免疫複合体
|
US10689447B2
(en)
|
2011-02-04 |
2020-06-23 |
Genentech, Inc. |
Fc variants and methods for their production
|
MX355255B
(es)
|
2011-02-04 |
2018-04-11 |
Genentech Inc |
Variantes de fc y métodos para su producción.
|
EP3138581B1
(de)
|
2011-03-17 |
2019-01-02 |
The University of Birmingham |
Umgelenkte immuntherapie
|
US9150846B2
(en)
|
2011-07-05 |
2015-10-06 |
Bioasis Technologies, Inc. |
P97-antibody conjugates and methods of use
|
EP3321281B1
(de)
|
2011-08-05 |
2019-11-27 |
biOasis Technologies Inc |
P97-fragmente mit transferaktivität
|
US9273143B2
(en)
|
2011-09-30 |
2016-03-01 |
Regeneron Pharmaceuticals, Inc. |
Methods and compositions comprising a combination of an anti-ErbB3 antibody and an anti-EGFR antibody
|
US8791244B2
(en)
|
2011-09-30 |
2014-07-29 |
Regeneron Pharmaceuticals, Inc. |
Anti-ErbB3 antibodies and uses thereof
|
EP3559049A4
(de)
|
2011-10-28 |
2019-12-04 |
Teva Pharmaceuticals Australia Pty Ltd |
Polypeptidkonstrukte und anwendungen davon
|
SG11201402343SA
(en)
|
2011-11-21 |
2014-06-27 |
Immunogen Inc |
Method of treatment of tumors that are resistant to egfr therapies by egfr antibody cytotoxic agent conjugate
|
CA2861610A1
(en)
|
2011-12-30 |
2013-07-04 |
Abbvie Inc. |
Dual specific binding proteins directed against il-13 and/or il-17
|
US9872904B2
(en)
|
2012-03-21 |
2018-01-23 |
Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V. |
Photoimmunoconjugates for use in photodynamic therapy
|
JP6441792B2
(ja)
*
|
2012-05-17 |
2018-12-19 |
ソレント・セラピューティクス・インコーポレイテッドSorrento Therapeutics, Inc. |
Egfrに結合する抗原結合蛋白質
|
TW201843172A
(zh)
|
2012-06-25 |
2018-12-16 |
美商再生元醫藥公司 |
抗-egfr抗體及其用途
|
ES2647082T3
(es)
|
2012-07-31 |
2017-12-19 |
Bioasis Technologies Inc |
Proteínas desfosforiladas de la enfermedad de depósito lisosómico y métodos de uso de las mismas
|
CA2890263C
(en)
|
2012-11-01 |
2020-03-10 |
Abbvie Inc. |
Anti-vegf/dll4 dual variable domain immunoglobulins and uses thereof
|
WO2014160438A1
(en)
|
2013-03-13 |
2014-10-02 |
Bioasis Technologies Inc. |
Fragments of p97 and uses thereof
|
CN105324396A
(zh)
|
2013-03-15 |
2016-02-10 |
艾伯维公司 |
针对IL-1β和/或IL-17的双重特异性结合蛋白
|
PT3677591T
(pt)
|
2013-04-29 |
2023-02-17 |
Teva Pharmaceuticals Australia Pty Ltd |
Anticorpos anti-cd38 e fusões a interferão alfa-2b atenuado
|
US11117975B2
(en)
|
2013-04-29 |
2021-09-14 |
Teva Pharmaceuticals Australia Pty Ltd |
Anti-CD38 antibodies and fusions to attenuated interferon alpha-2B
|
US20150093399A1
(en)
|
2013-08-28 |
2015-04-02 |
Bioasis Technologies, Inc. |
Cns-targeted conjugates having modified fc regions and methods of use thereof
|
WO2015117121A1
(en)
|
2014-02-03 |
2015-08-06 |
Bioasis Technologies, Inc. |
P97 fusion proteins
|
US10392605B2
(en)
|
2014-02-19 |
2019-08-27 |
Bioasis Technologies Inc. |
P97-IDS fusion proteins
|
WO2015168521A2
(en)
|
2014-05-01 |
2015-11-05 |
Bioasis Technologies, Inc. |
P97-polynucleotide conjugates
|
UA119352C2
(uk)
|
2014-05-01 |
2019-06-10 |
Тева Фармасьютикалз Острейліа Пті Лтд |
Комбінація леналідоміду або помалідоміду і конструкції анти-cd38 антитіло-атенуйований інтерферон альфа-2b та спосіб лікування суб'єкта, який має cd38-експресуючу пухлину
|
CA2943707A1
(en)
|
2014-05-06 |
2015-11-12 |
Genentech, Inc. |
Production of heteromultimeric proteins using mammalian cells
|
AU2015273353B2
(en)
|
2014-06-13 |
2020-09-10 |
Tenboron Oy |
Conjugates comprising an anti-EGFR1 antibody
|
SG11201703251TA
(en)
|
2014-10-29 |
2017-05-30 |
Teva Pharmaceuticals Australia Pty Ltd |
INTERFERON α2B VARIANTS
|
US10093733B2
(en)
|
2014-12-11 |
2018-10-09 |
Abbvie Inc. |
LRP-8 binding dual variable domain immunoglobulin proteins
|
JP6688551B2
(ja)
|
2015-05-21 |
2020-04-28 |
ハープーン セラピューティクス,インク. |
三重特異性結合タンパク質と使用方法
|
TW201710286A
(zh)
|
2015-06-15 |
2017-03-16 |
艾伯維有限公司 |
抗vegf、pdgf及/或其受體之結合蛋白
|
JP7002446B2
(ja)
|
2015-09-21 |
2022-03-04 |
アプティーボ リサーチ アンド デベロップメント エルエルシー |
Cd3結合ポリペプチド
|
CN119060177A
(zh)
|
2016-05-20 |
2024-12-03 |
哈普恩治疗公司 |
单结构域血清白蛋白结合蛋白质
|
US11623958B2
(en)
|
2016-05-20 |
2023-04-11 |
Harpoon Therapeutics, Inc. |
Single chain variable fragment CD3 binding proteins
|
JP7241677B2
(ja)
|
2016-07-19 |
2023-03-17 |
テバ・ファーマシューティカルズ・オーストラリア・ピーティワイ・リミテッド |
抗cd47併用療法
|
WO2018152033A1
(en)
*
|
2017-02-14 |
2018-08-23 |
Promab Biotechnologies, Inc. |
Cd47-car-t cells
|
US11535668B2
(en)
|
2017-02-28 |
2022-12-27 |
Harpoon Therapeutics, Inc. |
Inducible monovalent antigen binding protein
|
WO2018209298A1
(en)
|
2017-05-12 |
2018-11-15 |
Harpoon Therapeutics, Inc. |
Mesothelin binding proteins
|
WO2018218633A1
(en)
|
2017-06-02 |
2018-12-06 |
Beijing Percans Oncology Co. Ltd. |
Combination therapies for treating cancers
|
IL315737A
(en)
|
2017-10-13 |
2024-11-01 |
Harpoon Therapeutics Inc |
B-cell maturation antigen-binding proteins
|
CN109879964B
(zh)
*
|
2017-12-06 |
2022-08-05 |
北京科立思维生物科技有限公司 |
抗egfr单链抗体、抗pd1单链抗体及融合蛋白
|
WO2019195959A1
(en)
|
2018-04-08 |
2019-10-17 |
Cothera Biosciences, Inc. |
Combination therapy for cancers with braf mutation
|
MX2021001749A
(es)
|
2018-08-13 |
2021-05-27 |
Beijing Percans Oncology Co Ltd |
Biomarcadores para terapia contra el cancer.
|
WO2020061482A1
(en)
|
2018-09-21 |
2020-03-26 |
Harpoon Therapeutics, Inc. |
Egfr binding proteins and methods of use
|
CN113286817B
(zh)
|
2018-09-25 |
2025-01-28 |
哈普恩治疗公司 |
Dll3结合蛋白及使用方法
|
EP3897851A2
(de)
|
2018-12-17 |
2021-10-27 |
Revitope Limited |
Doppelimmunzell-engager
|
CA3181566A1
(en)
*
|
2020-04-30 |
2021-11-04 |
Board Of Regents, The University Of Texas System |
Anti-cd79b antibodies and chimeric antigen receptors and methods of use thereof
|
CA3128035A1
(en)
|
2020-08-13 |
2022-02-13 |
Bioasis Technologies, Inc. |
Combination therapies for delivery across the blood brain barrier
|
CA3187272A1
(en)
|
2020-10-08 |
2022-04-14 |
Thorsten Ross |
Trispecific binders
|
JP2024529381A
(ja)
|
2021-07-30 |
2024-08-06 |
アフィメド ゲーエムベーハー |
デュプレックスボディ
|
AU2022382368A1
(en)
|
2021-11-03 |
2024-05-02 |
Affimed Gmbh |
Bispecific cd16a binders
|
CN119101160B
(zh)
*
|
2024-10-25 |
2025-02-11 |
江苏百英生物科技有限公司 |
一种抗cd28纳米抗体、基于天然库筛选cd28纳米抗体的方法及其应用
|