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AR034268A1 - Compuestos derivados de piperidina, su uso en preparacion de medicamentos, composicion farmaceutica, metodo de tratamiento y proceso para su preparacion - Google Patents

Compuestos derivados de piperidina, su uso en preparacion de medicamentos, composicion farmaceutica, metodo de tratamiento y proceso para su preparacion

Info

Publication number
AR034268A1
AR034268A1 ARP010104833A ARP010104833A AR034268A1 AR 034268 A1 AR034268 A1 AR 034268A1 AR P010104833 A ARP010104833 A AR P010104833A AR P010104833 A ARP010104833 A AR P010104833A AR 034268 A1 AR034268 A1 AR 034268A1
Authority
AR
Argentina
Prior art keywords
preparation
piperidine
medicines
pharmaceutical composition
treatment method
Prior art date
Application number
ARP010104833A
Other languages
English (en)
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of AR034268A1 publication Critical patent/AR034268A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Compuestos de la fórmula (1), en donde: R representa un átomo de halógeno o un grupo alquilo C1-4; R1 representa un grupo alquilo C1-4; R2 representa hidrógeno o un grupo alquilo C1-4; R3 representa hidrógeno o un grupo alquilo C1-4; R4 representa un grupo trifluorometilo; R5 representa hidrógeno, un grupo alquilo C1-4 o C(O)R6; R6 representa alquilo C1-4, cicloalquilo C3-7, NH(alquilo C1-4) ó N(alquilo C1-4)2; m es 0 ó un número entero de 1 a 3; n es un número entero de 1 a 3; y sales y solvatos del mismo farmacéuticamente aceptables; también se describen procesos para su preparación, su uso en el tratamiento de condiciones mediadas por taquicininas, composiciones que contienen dichos compuestos.
ARP010104833A 2000-10-17 2001-10-15 Compuestos derivados de piperidina, su uso en preparacion de medicamentos, composicion farmaceutica, metodo de tratamiento y proceso para su preparacion AR034268A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0025354.2A GB0025354D0 (en) 2000-10-17 2000-10-17 Chemical compounds

Publications (1)

Publication Number Publication Date
AR034268A1 true AR034268A1 (es) 2004-02-18

Family

ID=9901397

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP010104833A AR034268A1 (es) 2000-10-17 2001-10-15 Compuestos derivados de piperidina, su uso en preparacion de medicamentos, composicion farmaceutica, metodo de tratamiento y proceso para su preparacion

Country Status (29)

Country Link
US (5) US7119092B2 (es)
EP (4) EP1524266B1 (es)
JP (1) JP3940359B2 (es)
KR (1) KR100847414B1 (es)
CN (1) CN1231468C (es)
AR (1) AR034268A1 (es)
AT (3) ATE355271T1 (es)
AU (4) AU9572301A (es)
BR (1) BR0114637A (es)
CA (1) CA2425876C (es)
CY (1) CY1107634T1 (es)
CZ (1) CZ299824B6 (es)
DE (3) DE60106287T2 (es)
DK (2) DK1524266T3 (es)
ES (3) ES2282794T3 (es)
GB (1) GB0025354D0 (es)
HK (2) HK1058788A1 (es)
HU (1) HU228146B1 (es)
IL (3) IL155165A0 (es)
MX (1) MXPA03003536A (es)
MY (1) MY124957A (es)
NO (1) NO324468B1 (es)
NZ (1) NZ525091A (es)
PL (1) PL203071B1 (es)
PT (2) PT1326832E (es)
SI (2) SI1326832T1 (es)
TW (1) TWI299730B (es)
WO (1) WO2002032867A1 (es)
ZA (1) ZA200302801B (es)

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Also Published As

Publication number Publication date
IL155165A (en) 2008-11-26
EP1921064A1 (en) 2008-05-14
US20080021041A1 (en) 2008-01-24
DK1524266T3 (da) 2007-06-25
AU2009201407B2 (en) 2011-12-15
NO20031561D0 (no) 2003-04-07
JP2004511544A (ja) 2004-04-15
MY124957A (en) 2006-07-31
IL191486A0 (en) 2008-11-03
PT1326832E (pt) 2005-01-31
EP1524266A1 (en) 2005-04-20
EP1752449A1 (en) 2007-02-14
GB0025354D0 (en) 2000-11-29
ES2282794T3 (es) 2007-10-16
DE60106287D1 (de) 2004-11-11
TWI299730B (en) 2008-08-11
ATE355271T1 (de) 2006-03-15
CA2425876A1 (en) 2002-04-25
SI1326832T1 (en) 2005-02-28
PL203071B1 (pl) 2009-08-31
AU2005204234B2 (en) 2009-05-07
US20040014770A1 (en) 2004-01-22
US20100081667A1 (en) 2010-04-01
EP1326832B1 (en) 2004-10-06
US7294630B2 (en) 2007-11-13
CN1231468C (zh) 2005-12-14
MXPA03003536A (es) 2003-08-07
AU9572301A (en) 2002-04-29
ATE468324T1 (de) 2010-06-15
ATE278669T1 (de) 2004-10-15
PT1524266E (pt) 2007-05-31
NZ525091A (en) 2005-04-29
EP1921064B1 (en) 2010-05-19
US7119092B2 (en) 2006-10-10
DE60127002T2 (de) 2007-10-31
IL155165A0 (en) 2003-10-31
AU2009201407A1 (en) 2009-05-07
HK1075889A1 (en) 2005-12-30
CN1483025A (zh) 2004-03-17
CZ299824B6 (cs) 2008-12-03
CZ20031082A3 (cs) 2004-08-18
ES2227287T3 (es) 2005-04-01
JP3940359B2 (ja) 2007-07-04
EP1326832A1 (en) 2003-07-16
PL361180A1 (en) 2004-09-20
ZA200302801B (en) 2004-04-21
US7060702B2 (en) 2006-06-13
ES2346108T3 (es) 2010-10-08
US20060142302A1 (en) 2006-06-29
DE60106287T2 (de) 2006-02-23
HK1058788A1 (en) 2004-06-04
HUP0301459A2 (en) 2006-09-28
US7648990B2 (en) 2010-01-19
DE60127002D1 (de) 2007-04-12
EP1524266B1 (en) 2007-02-28
AU2001295723B2 (en) 2005-05-26
CY1107634T1 (el) 2013-04-18
NO20031561L (no) 2003-06-14
AU2005204234A1 (en) 2005-09-15
BR0114637A (pt) 2003-09-30
HUP0301459A3 (en) 2007-11-28
CA2425876C (en) 2009-07-07
KR100847414B1 (ko) 2008-07-18
KR20030036932A (ko) 2003-05-09
NO324468B1 (no) 2007-10-22
DK1326832T3 (da) 2005-01-31
HU228146B1 (en) 2012-12-28
US20050137208A1 (en) 2005-06-23
SI1524266T1 (sl) 2007-08-31
DE60142197D1 (de) 2010-07-01
WO2002032867A1 (en) 2002-04-25

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