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Many cuts to ruin: a comprehensive update of caspase substrates

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1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

2 references

Europe PubMed Central

3 October 2022

Many cuts to ruin: a comprehensive update of caspase substrates (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

author name string

Fischer U

1

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Jänicke RU

2

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Schulze-Osthoff K

3

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

publication date

1 January 2003

2 references

Europe PubMed Central

PubMed publication ID

6 August 2017

3 October 2022

Cell Death & Differentiation

2 references

Europe PubMed Central

PubMed publication ID

6 August 2017

3 October 2022

10

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

76-100

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

B cell receptor cross-linking prevents Fas-induced cell death by inactivating the IL-1 beta-converting enzyme protease and regulating Bcl-2/Bcl-x expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of the Bloom's syndrome gene product during apoptosis by caspase-3 results in an impaired interaction with topoisomerase IIIalpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic cleavage of ras GTPase-activating protein during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-mediated cleavage of the TIAM1 guanine nucleotide exchange factor during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the Drosophila NF-kappaB factor Relish by rapid endoproteolytic cleavage

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the MDM2 oncoprotein as a substrate for CPP32-like apoptotic proteases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiological and pathological caspase cleavage of the neuronal RasGEF GRASP-1 as detected using a cleavage site-specific antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct cleavage products of nuclear proteins in apoptosis and necrosis revealed by autoantibody probes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A caspase cleavage fragment of p115 induces fragmentation of the Golgi apparatus and apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic cleavage and activation of protein kinase C [micro] by caspase-3 in the apoptotic response of cells to 1-beta -D-arabinofuranosylcytosine and other genotoxic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-mediated fragmentation of calpain inhibitor protein calpastatin during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The 72-kDa component of signal recognition particle is cleaved during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The La (SS-B) autoantigen, a key protein in RNA biogenesis, is dephosphorylated and cleaved early during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-dependent activation of cyclin-dependent kinases during Fas-induced apoptosis in Jurkat cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase activation is required for terminal erythroid differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau cleavage and dephosphorylation in cerebellar granule neurons undergoing apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-3 mediated cleavage of BRCA1 during UV-induced apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The development-associated cleavage of lens connexin 45.6 by caspase-3-like protease is regulated by casein kinase II-mediated phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of NRF2, a member of the NF-E2 family of transcription factors, as a substrate for caspase-3(-like) proteases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p28 Bap31, a Bcl-2/Bcl-XL- and procaspase-8-associated protein in the endoplasmic reticulum

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Active caspase-8 translocates into the nucleus of apoptotic cells to inactivate poly(ADP-ribose) polymerase-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of actin by interleukin 1 beta-converting enzyme to reverse DNase I inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage and shedding of E-cadherin after induction of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of atrophin-1 at caspase site aspartic acid 109 modulates cytotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma membrane Ca2+ATPase isoform 4b is cleaved and activated by caspase-3 during the early phase of apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The fate of U1 snRNP during anti-Fas induced apoptosis: specific cleavage of the U1 snRNA molecule

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of CDK inhibitor p21(Cip1/Waf1) by caspases is an early event during DNA damage-induced apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cdc42 is a substrate for caspases and influences Fas-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic cleavage of the mdm2 oncoprotein during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Non-erythroid alpha-spectrin breakdown by calpain and interleukin 1 beta-converting-enzyme-like protease(s) in apoptotic cells: contributory roles of both protease families in neuronal apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylserine externalization during CD95-induced apoptosis of cells and cytoplasts requires ICE/CED-3 protease activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Baculovirus apoptotic suppressor P49 is a substrate inhibitor of initiator caspases resistant to P35 in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Limited caspase cleavage of human BAP31.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of atypical protein kinase C zeta by caspase processing and degradation by the ubiquitin-proteasome system

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic activation of PKN by caspase-3 or related protease during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-dependent cleavage of ErbB-2 by geldanamycin and staurosporin

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The RET proto-oncogene induces apoptosis: a novel mechanism for Hirschsprung disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase 7-induced cleavage of kinectin in apoptotic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

D4-GDI, a substrate of CPP32, is proteolyzed during Fas-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of bid by casein kinases I and II regulates its cleavage by caspase 8.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-dependent proteolysis of integral and peripheral proteins of nuclear membranes and nuclear pore complex proteins during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-mediated cleavage of adenovirus early region 1A proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of keratins 18, 19 and heat-shock protein 90 beta as candidate substrates of proteolysis during ionizing radiation-induced apoptosis of estrogen-receptor negative breast tumor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-dependent N-terminal cleavage of influenza virus nucleocapsid protein in infected cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fas-induced arachidonic acid release is mediated by Ca2+-independent phospholipase A2 but not cytosolic phospholipase A2, which undergoes proteolytic inactivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The regulation of anoikis: MEKK-1 activation requires cleavage by caspases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spodoptera frugiperda caspase-1, a novel insect death protease that cleaves the nuclear immunophilin FKBP46, is the target of the baculovirus antiapoptotic protein p35.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of the Serum Response Factor during Death Receptor-induced Apoptosis Results in an Inhibition of the c-FOSPromoter Transcriptional Activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of focal adhesion kinase by caspases during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Caenorhabditis elegans sex determination protein FEM-1 is a CED-3 substrate that associates with CED-4 and mediates apoptosis in mammalian cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-mediated parkin cleavage in apoptotic cell death.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of caspase 3-mediated cleavage and functional alteration of eukaryotic initiation factor 2alpha in apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of focal adhesions mediates detachment during neuronal apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcription factor AP-2alpha is preferentially cleaved by caspase 6 and degraded by proteasome during tumor necrosis factor alpha-induced apoptosis in breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presenilins are processed by caspase-type proteases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear changes in necrotic HL-60 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-mediated calcineurin activation contributes to IL-2 release during T cell activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predominant identification of RNA-binding proteins in Fas-induced apoptosis by proteome analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The large subunit of the DNA replication complex C (DSEB/RF-C140) cleaved and inactivated by caspase-3 (CPP32/YAMA) during Fas-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase activation is required for T cell proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-mediated cleavage of actin-binding and SH3-domain-containing proteins cortactin, HS1, and HIP-55 during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of pro-caspase-7 by serine proteases includes a non-canonical specificity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptotic cleavage of cytoplasmic dynein intermediate chain and p150(Glued) stops dynein-dependent membrane motility.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of AHNAK as a novel autoantigen in systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Developmentally regulated activation of apoptosis early in Xenopus gastrulation results in cyclin A degradation during interphase of the cell cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The gamma subunit of the rod photoreceptor cGMP phosphodiesterase can modulate the proteolysis of two cGMP binding cGMP-specific phosphodiesterases (PDE6 and PDE5) by caspase-3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of polypeptide chain initiation factor eIF4GI during apoptosis in lymphoma cells: characterisation of an internal fragment generated by caspase-3-mediated cleavage

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolysis of human eukaryotic translation initiation factor eIF4GII, but not eIF4GI, coincides with the shutoff of host protein synthesis after poliovirus infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cleavage of Akt/protein kinase B by death receptor signaling is an important event in detachment-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cAMP-specific phosphodiesterase PDE4A5 is cleaved downstream of its SH3 interaction domain by caspase-3. Consequences for altered intracellular distribution

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human autoimmune sera as molecular probes for the identification of an autoantigen kinase signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-mediated degradation of T-cell receptor zeta-chain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-mediated cleavage of focal adhesion kinase pp125FAK and disassembly of focal adhesions in human endothelial cell apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The fate of the nuclear matrix-associated-region-binding protein SATB1 during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of the interaction of mammalian protein synthesis eukaryotic initiation factor 4B with the poly(A)-binding protein by caspase- and viral protease-mediated cleavages

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective degradation of the PKC-epsilon isoform during cell death in AKR-2B fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional characterization of DNase X, a novel endonuclease expressed in muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dominant-interfering forms of MEF2 generated by caspase cleavage contribute to NMDA-induced neuronal apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The EMAPII cytokine is released from the mammalian multisynthetase complex after cleavage of its p43/proEMAPII component

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in integrity and association of eukaryotic protein synthesis initiation factors during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The adenomatous polyposis coli protein and retinoblastoma protein are cleaved early in apoptosis and are potential substrates for caspases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular cloning of the interleukin-1 beta converting enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of endothelial monocyte-activating polypeptide II release by apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of protein phosphatase 2A activity by caspase-3 during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pro-B-cell-specific transcription and proapoptotic function of protein kinase Ceta

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase cleavage of the transcription factor FLI-1 during preB leukemic cell death.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of rabaptin-5 blocks endosome fusion during apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspases disrupt the nuclear-cytoplasmic barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The fate of desmosomal proteins in apoptotic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-mediated cleavage of the ubiquitin-protein ligase Nedd4 during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-mediated cleavage of APC results in an amino-terminal fragment with an intact armadillo repeat domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional discontinuities in prothymosin alpha caused by caspase cleavage in apoptotic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspases cleave focal adhesion kinase during apoptosis to generate a FRNK-like polypeptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific cleavage of the 70-kDa protein component of the U1 small nuclear ribonucleoprotein is a characteristic biochemical feature of apoptotic cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fas-induced proteolytic activation and intracellular redistribution of the stress-signaling kinase MEKK1

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspases mediate retinoic acid-induced degradation of the acute promyelocytic leukemia PML/RARalpha fusion protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteome analysis of nuclear matrix proteins during apoptotic chromatin condensation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PITSLRE protein kinase activity is associated with apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conversion of Bcl-2 to a Bax-like death effector by caspases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-dependent cleavage and inactivation of the Vav1 proto-oncogene product during apoptosis prevents IL-2 transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic activation of protein kinase C delta by an ICE/CED 3-like protease induces characteristics of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-2 is localized at the Golgi complex and cleaves golgin-160 during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of caspase-1 and caspase-3 in the production and processing of mature human interleukin 18 in monocytic THP.1 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-mediated proteolytic activation of calcineurin in thapsigargin-mediated apoptosis in SH-SY5Y neuroblastoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neuronal microtubule-associated protein tau is a substrate for caspase-3 and an effector of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simultaneous Degradation of αII- and βII-Spectrin by Caspase 3 (CPP32) in Apoptotic Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic activation of MST/Krs, STE20-related protein kinase, by caspase during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiapoptotic herpesvirus Bcl-2 homologs escape caspase-mediated conversion to proapoptotic proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase I-related protease inhibition retards the execution of okadaic acid- and camptothecin-induced apoptosis and PAI-2 cleavage, but not commitment to cell death in HL-60 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamic changes of NuMA during the cell cycle and possible appearance of a truncated form of NuMA during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage and phosphorylation of XRCC4 protein induced by X-irradiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific proteolysis of the kinase protein kinase C-related kinase 2 by caspase-3 during apoptosis. Identification by a novel, small pool expression cloning strategy

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-3 cleaves Apaf-1 into an approximately 30 kDa fragment that associates with an inappropriately oligomerized and biologically inactive approximately 1.4 MDa apoptosome complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SPAK, a STE20/SPS1-related kinase that activates the p38 pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase cleavage enhances the apoptosis-inducing effects of BAD.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of beta-catenin and plakoglobin and shedding of VE-cadherin during endothelial apoptosis: evidence for a role for caspases and metalloproteinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Limited proteolysis of filamin is catalyzed by caspase-3 in U937 and Jurkat cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early activation of caspases during T lymphocyte stimulation results in selective substrate cleavage in nonapoptotic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The adapter protein apoptotic protease-activating factor-1 (Apaf-1) is proteolytically processed during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA-dependent protein kinase catalytic subunit: a target for an ICE-like protease in apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic cleavage of HsRad51 during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dentatorubral pallidoluysian atrophy (DRPLA) protein is cleaved by caspase-3 during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

F1Aalpha, a death receptor-binding protein homologous to the Caenorhabditis elegans sex-determining protein, FEM-1, is a caspase substrate that mediates apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The RasGAP N-terminal Fragment Generated by Caspase Cleavage Protects Cells in a Ras/PI3K/Akt-dependent Manner That Does Not Rely on NFκB Activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p41 as a possible marker for cell death is generated by caspase cleavage of p42/SETbeta in irradiated MOLT-4 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted proteolysis of the focal adhesion kinase pp125 FAK during c-MYC-induced apoptosis is suppressed by integrin signalling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase proteolysis of the cohesin component RAD21 promotes apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome c release, mitochondrial membrane depolarization, caspase-3 activation, and Bax-alpha cleavage during IFN-alpha-induced apoptosis in Daudi B lymphoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-mediated cleavage of TRAF3 in FasL-stimulated Jurkat-T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The hepatitis C virus core protein interacts with NS5A and activates its caspase-mediated proteolytic cleavage

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-dependent activation of calpain during drug-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myocyte enhancer factor 2A and 2D undergo phosphorylation and caspase-mediated degradation during apoptosis of rat cerebellar granule neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-induced proteolysis of the cyclin-dependent kinase inhibitor p27Kip1 mediates its anti-apoptotic activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inositol 1,4,5-trisphosphate receptor type 1 is a substrate for caspase-3 and is cleaved during apoptosis in a caspase-3-dependent manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase 3 cleavage of the Ste20-related kinase SLK releases and activates an apoptosis-inducing kinase domain and an actin-disassembling region

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

pp60(cSrc) is a caspase-3 substrate and Is essential for the transformed phenotype of A431 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspases mediate nucleoporin cleavage, but not early redistribution of nuclear transport factors and modulation of nuclear permeability in apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Death by a thousand cuts: an ever increasing list of caspase substrates

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage and relocation of the tyrosine kinase P59FYN during Fas-mediated apoptosis in T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid cytochrome c release, activation of caspases 3, 6, 7 and 8 followed by Bap31 cleavage in HeLa cells treated with photodynamic therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolysis of heat shock transcription factor is associated with apoptosis in rat Nb2 lymphoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-induced inactivation of the anti-apoptotic TRAF1 during Fas ligand-mediated apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Filamin (280-kDa Actin-binding Protein) Is a Caspase Substrate and Is Also Cleaved Directly by the Cytotoxic T Lymphocyte Protease Granzyme B during Apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

xIAP induces cell-cycle arrest and activates nuclear factor-kappaB : new survival pathways disabled by caspase-mediated cleavage during apoptosis of human endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus p35 protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of Helicard, a CARD-containing helicase cleaved during apoptosis, accelerates DNA degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In acute promyelocytic leukemia NB4 cells, the synthetic retinoid CD437 induces contemporaneously apoptosis, a caspase-3-mediated degradation of PML/RARalpha protein and the PML retargeting on PML-nuclear bodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vitamin D(3)-induced apoptosis of murine squamous cell carcinoma cells. Selective induction of caspase-dependent MEK cleavage and up-regulation of MEKK-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective cleavage of nuclear autoantigens during CD95 (Fas/APO-1)-mediated T cell apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific cleavage of the large subunit of replication factor C in apoptosis is mediated by CPP32-like protease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiapoptotic signaling generated by caspase-induced cleavage of RasGAP.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-mediated inhibition of human cytosolic phospholipase A2 during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RNA polymerase II large subunit is cleaved by caspases during DNA damage-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The fate of E- and P-cadherin during the early stages of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-mediated cleavage of the stacking protein GRASP65 is required for Golgi fragmentation during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The caspase-cleaved DAP5 protein supports internal ribosome entry site-mediated translation of death proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis of the teratocarcinoma cell line Tera-1 leads to the cleavage of HERV-K10gag proteins by caspases and/or granzyme B.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation and caspase-mediated inhibition of PARP: a molecular switch between fibroblast necrosis and apoptosis in death receptor signaling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic processing of the Alzheimer's disease amyloid precursor protein within its cytoplasmic domain by caspase-like proteases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p21-activated kinase (PAK) is required for Fas-induced JNK activation in Jurkat cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contribution to antimitochondrial antibody production: cleavage of pyruvate dehydrogenase complex-E2 by apoptosis-related proteases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-mediated cleavage and functional changes of hematopoietic progenitor kinase 1 (HPK1)

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calsenilin is a substrate for caspase-3 that preferentially interacts with the familial Alzheimer's disease-associated C-terminal fragment of presenilin 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential requirements for caspase-8 activity in the mechanism of phosphorylation of eIF2alpha, cleavage of eIF4GI and signaling events associated with the inhibition of protein synthesis in apoptotic Jurkat T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase cleavage of initiation factor 4E-binding protein 1 yields a dominant inhibitor of cap-dependent translation and reveals a novel regulatory motif

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of hPAK65 by caspase cleavage induces some of the morphological and biochemical changes of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific cleavage of alpha-fodrin during Fas- and tumor necrosis factor-induced apoptosis is mediated by an interleukin-1beta-converting enzyme/Ced-3 protease distinct from the poly(ADP-ribose) polymerase protease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-dependent cleavage of cadherins and catenins during osteoblast apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-mediated cleavage of DNA topoisomerase I at unconventional sites during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-mediated cleavage of eukaryotic translation initiation factor subunit 2alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of purified neuronal clathrin assembly protein (CALM) by caspase 3 and calpain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascade

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The novel SAR-binding domain of scaffold attachment factor A (SAF-A) is a target in apoptotic nuclear breakdown.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NS1 protein of influenza A virus down-regulates apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective cleavage of BLM, the bloom syndrome protein, during apoptotic cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting of the transcription factor Max during apoptosis: phosphorylation-regulated cleavage by caspase-5 at an unusual glutamic acid residue in position P1

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lamin proteolysis facilitates nuclear events during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53 inhibits alpha 6 beta 4 integrin survival signaling by promoting the caspase 3-dependent cleavage of AKT/PKB

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

c-IAP1 is cleaved by caspases to produce a proapoptotic C-terminal fragment

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a caspase-9 substrate and detection of its cleavage in programmed cell death during mouse development

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Posttranslational N-myristoylation of BID as a molecular switch for targeting mitochondria and apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-cleaved TRAF1 negatively regulates the antiapoptotic signals of TRAF2 during TNF-induced cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective down-regulation of IP(3)receptor subtypes by caspases and calpain during TNF alpha -induced apoptosis of human T-lymphoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Degradation of the type I inositol 1,4,5-trisphosphate receptor by caspase-3 in SH-SY5Y neuroblastoma cells undergoing apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-dependent cleavage of carbamoyl phosphate synthetase II during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of translation initiation factor 4G (eIF4G) during anti-Fas IgM-induced apoptosis does not require signalling through the p38 mitogen-activated protein (MAP) kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Drosophila caspase DRONC cleaves following glutamate or aspartate and is regulated by DIAP1, HID, and GRIM.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase 7 can cleave tumor necrosis factor receptor-I (p60) at a non-consensus motif, in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel form of DAP5 protein accumulates in apoptotic cells as a result of caspase cleavage and internal ribosome entry site-mediated translation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-mediated cleavage of hematopoietic progenitor kinase 1 (HPK1) converts an activator of NFkappaB into an inhibitor of NFkappaB

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-3-Dependent Cleavage of the Glutamate-L-Cysteine Ligase Catalytic Subunit during Apoptotic Cell Death

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis overrides survival signals through a caspase-mediated dominant-negative NF-kappa B loop

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TRAF1 is a substrate of caspases activated during tumor necrosis factor receptor-alpha-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dismantling cell-cell contacts during apoptosis is coupled to a caspase-dependent proteolytic cleavage of beta-catenin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-3-mediated cleavage of protein kinase C theta in induction of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD95 (Fas)-induced caspase-mediated proteolysis of NF-kappaB

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the execution phase of apoptosis in vitro using extracts from condemned-phase cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoantigens as substrates for apoptotic proteases: implications for the pathogenesis of systemic autoimmune disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Linkage of caspase-mediated degradation of paxillin to apoptosis in Ba/F3 murine pro-B lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of the actin-capping protein alpha -adducin at Asp-Asp-Ser-Asp633-Ala by caspase-3 is preceded by its phosphorylation on serine 726 in cisplatin-induced apoptosis of renal epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-mediated cleavage of the Ca2+/calmodulin-dependent protein kinase-like kinase facilitates neuronal apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Fas-induced apoptosis analyzed by high throughput proteome analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human replication protein Cdc6 is selectively cleaved by caspase 3 during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53 expression in K562 cells is associated with caspase-mediated cleavage of c-ABL and BCR-ABL protein kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification of an interleukin-1 beta converting enzyme-related cysteine protease that cleaves sterol regulatory element-binding proteins between the leucine zipper and transmembrane domains

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

C/EBPbeta phosphorylation by RSK creates a functional XEXD caspase inhibitory box critical for cell survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Platelet formation is the consequence of caspase activation within megakaryocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of hTAF(II)80 delta links apoptotic signaling pathways to transcription factor TFIID function

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian caspases: structure, activation, substrates, and functions during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of Asp-462 in regulating Akt activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-mediated activation of a 36-kDa myelin basic protein kinase during anticancer drug-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin A

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the cytolinker plectin as a major early in vivo substrate for caspase 8 during CD95- and tumor necrosis factor receptor-mediated apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of actin-cleavable interleukin 1beta-converting enzyme (ICE) family protease CPP-32 during chemotherapeutic agent-induced apoptosis in ovarian carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic processing of the adherens junctions components beta-catenin and gamma-catenin/plakoglobin during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase activation of mammalian sterile 20-like kinase 3 (Mst3). Nuclear translocation and induction of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acinus is a caspase-3-activated protein required for apoptotic chromatin condensation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct roles of two intracellular phospholipase A2s in fatty acid release in the cell death pathway. Proteolytic fragment of type IVA cytosolic phospholipase A2alpha inhibits stimulus-induced arachidonate release, whereas that of type VI Ca2+-inde

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of Fyn and Lyn in their N-terminal unique regions during induction of apoptosis: a new mechanism for Src kinase regulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis-induced cleavage of beta-catenin by caspase-3 results in proteolytic fragments with reduced transactivation potential

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of hepatitis C virus nonstructural protein 5A by a caspase-like protease(s) in mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GAL4 is a substrate for caspases: implications for two-hybrid screening and other GAL4-based assays

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Huntington disease: new insights on the role of huntingtin cleavage

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of death receptor signals by cellular FLIP

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation of anti-apoptotic presenilin-2 polypeptides by alternative transcription, proteolysis, and caspase-3 cleavage

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The endothelial monocyte-activating polypeptide II (EMAP II) is a substrate for caspase-7.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of plasma membrane calcium pumps by caspases: a link between apoptosis and necrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microfilament reorganization during apoptosis: the role of Gas2, a possible substrate for ICE-like proteases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of cell death by Bcl-XL through caspase interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Staurosporine treatment and serum starvation promote the cleavage of emerin in cultured mouse myoblasts: involvement of a caspase-dependent mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase 3 activity is required for skeletal muscle differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic cleavage of phospholipase C-gamma1 during apoptosis in Molt-4 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning of MASK, a novel member of the mammalian germinal center kinase III subfamily, with apoptosis-inducing properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of IkappaB-alpha inhibits its cleavage by caspase CPP32 in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human RNA helicase A is a lupus autoantigen that is cleaved during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-mediated cleavage of p130cas in etoposide-induced apoptotic Rat-1 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamic O-glycosylation of nuclear and cytosolic proteins: further characterization of the nucleocytoplasmic beta-N-acetylglucosaminidase, O-GlcNAcase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Actin cleavage by CPP-32/apopain during the development of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of eukaryotic translation initiation factor 4GII correlates with translation inhibition during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolysis of the human DNA polymerase epsilon catalytic subunit by caspase-3 and calpain specifically during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic cleavage of cyclin E leads to inactivation of associated kinase activity and amplification of apoptosis in hematopoietic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The proteolytic cleavage of protein kinase C isotypes, which generates kinase and regulatory fragments, correlates with Fas-mediated and 12-O-tetradecanoyl-phorbol-13-acetate-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CREB is cleaved by caspases during neural cell apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The interleukin-1 receptor binds the human interleukin-1 alpha precursor but not the interleukin-1 beta precursor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic cleavage of epidermal growth factor receptor by caspases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for caspase-mediated cleavage of AMPA receptor subunits in neuronal apoptosis and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional consequences of caspase activation in cardiac myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A cloning method for caspase substrates that uses the yeast two-hybrid system: cloning of the antiapoptotic gene gelsolin

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SATB1 cleavage by caspase 6 disrupts PDZ domain-mediated dimerization, causing detachment from chromatin early in T-cell apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polypyrimidine tract-binding proteins are cleaved by caspase-3 during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial cell apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of PITSLRE kinases by ICE/CASP-1 and CPP32/CASP-3 during apoptosis induced by tumor necrosis factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Eukaryotic translation initiation factor 4G is targeted for proteolytic cleavage by caspase 3 during inhibition of translation in apoptotic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific cleavage of the retinoblastoma protein by an ICE-like protease in apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kennedy's disease: caspase cleavage of the androgen receptor is a crucial event in cytotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage and inactivation of ATM during apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resistance of actin to cleavage during apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotine preconditioning antagonizes activity-dependent caspase proteolysis of a glutamate receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD95/Fas induces cleavage of the GrpL/Gads adaptor and desensitization of antigen receptor signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase activation in the terminal differentiation of human epidermal keratinocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PARP is important for genomic stability but dispensable in apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis-induced cleavage of keratin 15 and keratin 17 in a human breast epithelial cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of interleukin-1 beta converting enzyme by the cowpox virus serpin CrmA. An example of cross-class inhibition.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heteronuclear Ribonucleoproteins C1 and C2, Components of the Spliceosome, Are Specific Targets of Interleukin 1β-converting Enzyme-like Proteases in Apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The viral nucleocapsid protein of transmissible gastroenteritis coronavirus (TGEV) is cleaved by caspase-6 and -7 during TGEV-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-3-mediated processing of poly(ADP-ribose) glycohydrolase during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The docking protein HEF1 is an apoptotic mediator at focal adhesion sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Eukaryotic initiation factor 4GII (eIF4GII), but not eIF4GI, cleavage correlates with inhibition of host cell protein synthesis after human rhinovirus infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Life and death decisions: regulation of apoptosis by proteolysis of signaling molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bacterial lipopolysaccharide disrupts endothelial monolayer integrity and survival signaling events through caspase cleavage of adherens junction proteins.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The large subunit of replication factor C is a substrate for caspase-3 in vitro and is cleaved by a caspase-3-like protease during Fas-mediated apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic activation of ETK/Bmx tyrosine kinase by caspases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific involvement of caspases in the differentiation of monocytes into macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Translation inhibition in apoptosis: caspase-dependent PKR activation and eIF2-alpha phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspases: more than just killers?

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Essential myosin light chain as a target for caspase-3 in failing myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of zetaPKC but not lambda/iotaPKC by caspase-3 during UV-induced apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LBR, a chromatin and lamin binding protein from the inner nuclear membrane, is proteolyzed at late stages of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolysis of the docking protein HEF1 and implications for focal adhesion dynamics

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase cleavage of members of the amyloid precursor family of proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-mediated cleavage of the chromosome-binding domain of lamina-associated polypeptide 2 alpha.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for caspases in lens fiber differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptotic cleavage of scaffold attachment factor A (SAF-A) by caspase-3 occurs at a noncanonical cleavage site

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protease Involvement in Fodrin Cleavage and Phosphatidylserine Exposure in Apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequence-specific DNA binding activity of RNA helicase A to the p16INK4a promoter

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential regulation and ATP requirement for caspase-8 and caspase-3 activation during CD95- and anticancer drug-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

STAT1 is inactivated by a caspase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct cleavage by the calcium-activated protease calpain can lead to inactivation of caspases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of Akt and its anti-apoptotic activities by tumor necrosis factor-induced protein kinase C-related kinase 2 (PRK2) cleavage

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of farnesyltransferase and geranylgeranyltransferase I by caspase-3: cleavage of the common alpha subunit during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of apoptosis-associated proteins in a human Burkitt lymphoma cell line. Cleavage of heterogeneous nuclear ribonucleoprotein A1 by caspase 3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MDMX stability is regulated by p53-induced caspase cleavage in NIH3T3 mouse fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis generates stable fragments of human type I keratins

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase cleavage of the nuclear autoantigen LEDGF/p75 abrogates its pro-survival function: implications for autoimmunity in atopic disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prothymosin alpha fragmentation in apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-dependent cleavage of the hematopoietic specific adaptor protein Gads alters signalling from the T cell receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium/calmodulin-dependent protein kinase IV is cleaved by caspase-3 and calpain in SH-SY5Y human neuroblastoma cells undergoing apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue transglutaminase is a caspase substrate during apoptosis. Cleavage causes loss of transamidating function and is a biochemical marker of caspase 3 activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of the calpain inhibitor, calpastatin, during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three mutations in v-Rel render it resistant to cleavage by cell-death protease caspase-3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of apoptosis by phosphatidylinositol 4,5-bisphosphate inhibition of caspases, and caspase inactivation of phosphatidylinositol phosphate 5-kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human homologue of the yeast polyubiquitination factor Ufd2p is cleaved by caspase 6 and granzyme B during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Yeast two-hybrid screening using constitutive-active caspase-7 as bait in the identification of PA28gamma as an effector caspase substrate

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Processing and activation of pro-interleukin-16 by caspase-3

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-3-induced gelsolin fragmentation contributes to actin cytoskeletal collapse, nucleolysis, and apoptosis of vascular smooth muscle cells exposed to proinflammatory cytokines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of death-inducing signaling complex (DISC) by pro-apoptotic C-terminal fragment of RIP

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinoid-induced apoptosis and Sp1 cleavage occur independently of transcription and require caspase activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic cleavage of protein kinase Cmu upon induction of apoptosis in U937 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase processing and nuclear export of CTP:phosphocholine cytidylyltransferase alpha during farnesol-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective proteolysis of the nuclear replication factor MCM3 in apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase cleavage of vimentin disrupts intermediate filaments and promotes apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective Rho GTPase regulation by IL-1 beta-converting enzyme-mediated cleavage of D4 GDP dissociation inhibitor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12655297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondria-targeting drugs arsenic trioxide and lonidamine bypass the resistance of TPA-differentiated leukemic cells to apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401160

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.CDD.4401160

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PMC publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

ResearchGate publication ID

0 references

Sitelinks

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