(Q41182414)

27 September 2017

title

Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract (English)

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27 September 2017

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27 September 2017

Y P Goldberg

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27 September 2017

D W Nicholson

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27 September 2017

D M Rasper

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27 September 2017

M A Kalchman

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27 September 2017

H B Koide

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27 September 2017

R K Graham

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27 September 2017

M Bromm

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27 September 2017

P Kazemi-Esfarjani

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27 September 2017

N A Thornberry

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27 September 2017

J P Vaillancourt

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27 September 2017

language of work or name

English

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publication date

1 August 1996

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

page(s)

442-449

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Genetic control of programmed cell death in the nematode C. elegans.

27 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNG0896-442

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0896-442

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0896-442

A worldwide study of the Huntington's disease mutation. The sensitivity and specificity of measuring CAG repeats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0896-442

Polyglutamine expansion as a pathological epitope in Huntington's disease and four dominant cerebellar ataxias

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0896-442

Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0896-442

DNA End Labeling (TUNEL) in Huntington's Disease and Other Neuropathological Conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0896-442

Absence of disease phenotype and intergenerational stability of the CAG repeat in transgenic mice expressing the human Huntington disease transcript

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0896-442

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0896-442

A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0896-442

Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus p35 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0896-442

Protease activation during apoptosis: death by a thousand cuts?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNG0896-442

7 January 2021

Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

1 reference

https://api.crossref.org/works/10.1038%2FNG0896-442

7 January 2021

DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNG0896-442

7 January 2021

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

https://api.crossref.org/works/10.1038%2FNG0896-442

7 January 2021

Widespread expression of Huntington's disease gene (IT15) protein product

1 reference

https://api.crossref.org/works/10.1038%2FNG0896-442

7 January 2021

Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons

1 reference

https://api.crossref.org/works/10.1038%2FNG0896-442

7 January 2021

Identification and localization of huntingtin in brain and human lymphoblastoid cell lines with anti-fusion protein antibodies

1 reference

https://api.crossref.org/works/10.1038%2FNG0896-442

7 January 2021

Evidence from antibody studies that the CAG repeat in the Huntington disease gene is expressed in the protein

1 reference

https://api.crossref.org/works/10.1038%2FNG0896-442

7 January 2021

Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models.

1 reference

https://api.crossref.org/works/10.1038%2FNG0896-442

7 January 2021

Inactivation of the mouse Huntington's disease gene homolog Hdh

1 reference

https://api.crossref.org/works/10.1038%2FNG0896-442

7 January 2021

Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue

1 reference

https://api.crossref.org/works/10.1038%2FNG0896-442

7 January 2021

SCA1 transgenic mice: A model for neurodegeneration caused by an expanded CAG trinucleotide repeat

1 reference

https://api.crossref.org/works/10.1038%2FNG0896-442

7 January 2021

ICE/CED3-like proteases as therapeutic targets for the control of inappropriate apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNG0896-442

7 January 2021

Molecular analysis of juvenile Huntington disease: the major influence on (CAG)n repeat length is the sex of the affected parent.

1 reference

https://api.crossref.org/works/10.1038%2FNG0896-442

7 January 2021

Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35.

1 reference

https://api.crossref.org/works/10.1038%2FNG0896-442

7 January 2021

Interleukin-1 beta converting enzyme.

1 reference

https://api.crossref.org/works/10.1038%2FNG0896-442

7 January 2021

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

1 reference

https://api.crossref.org/works/10.1038%2FNG0896-442

7 January 2021

Identifiers

DOI

10.1038/NG0896-442

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Dimensions Publication ID

27 September 2017

1049738686

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1 reference