(Q43636937)

25 November 2017

title

Caspase-dependent cleavage of ErbB-2 by geldanamycin and staurosporin (English)

1 reference

25 November 2017

Tikhomirov O

1 reference

25 November 2017

Carpenter G

series ordinal

1 reference

25 November 2017

language of work or name

English

0 references

publication date

11 June 2001

1 reference

Journal of Biological Chemistry

25 November 2017

published in

1 reference

25 November 2017

volume

276

1 reference

25 November 2017

1 reference

25 November 2017

page(s)

33675-33680

1 reference

Specificity within the EGF family/ErbB receptor family signaling network

25 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

The ErbB signaling network in embryogenesis and oncogenesis: signal diversification through combinatorial ligand-receptor interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

Different structural alterations upregulate in vitro tyrosine kinase activity and transforming potency of the erbB-2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

Increased expression of the putative growth factor receptor p185HER2 causes transformation and tumorigenesis of NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

Regulation of phosphorylation of the c-erbB-2/HER2 gene product by a monoclonal antibody and serum growth factor(s) in human mammary carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

HER-2/neu blocks tumor necrosis factor-induced apoptosis via the Akt/NF-kappaB pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

Herbimycin, a new antibiotic produced by a strain of Streptomyces

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

Immunoconjugates of geldanamycin and anti-HER2 monoclonal antibodies: antiproliferative activity on human breast carcinoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

The benzoquinone ansamycin geldanamycin stimulates proteolytic degradation of focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

The hsp90-based chaperone system: involvement in signal transduction from a variety of hormone and growth factor receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

The role of the hsp90-based chaperone system in signal transduction by nuclear receptors and receptors signaling via MAP kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

Steroid receptor interactions with heat shock protein and immunophilin chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

Progesterone receptor structure and function altered by geldanamycin, an hsp90-binding agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

Disruption of the Raf-1-Hsp90 Molecular Complex Results in Destabilization of Raf-1 and Loss of Raf-1-Ras Association

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

p185erbB2 binds to GRP94 in vivo. Dissociation of the p185erbB2/GRP94 heterocomplex by benzoquinone ansamycins precedes depletion of p185erbB2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

Polyubiquitination and proteasomal degradation of the p185c-erbB-2 receptor protein-tyrosine kinase induced by geldanamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

Geldanamycin induces ErbB-2 degradation by proteolytic fragmentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

Sensitivity of mature Erbb2 to geldanamycin is conferred by its kinase domain and is mediated by the chaperone protein Hsp90

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

Biochemical, cell biological and immunological issues surrounding the endoplasmic reticulum chaperone GRP94/gp96.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

Substrate and inhibitor specificity of interleukin-1 beta-converting enzyme and related caspases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

Caspase structure, proteolytic substrates, and function during apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

Caspases: the executioners of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

Apoptosis induction by the glucocorticoid hormone dexamethasone and the calcium-ATPase inhibitor thapsigargin involves Bc1-2 regulated caspase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

Requirement of an ICE-like protease for induction of apoptosis and ceramide generation by REAPER.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

ERBIN: a basolateral PDZ protein that interacts with the mammalian ERBB2/HER2 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

Herbimycin A and geldanamycin inhibit okadaic acid-induced apoptosis and p38 activation in NRK-52E renal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

Differential sensitivity of human mammary epithelial and breast carcinoma cell lines to curcumin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

Curcumin, an antioxidant and anti-tumor promoter, induces apoptosis in human leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

ERBB2 oncogene in human breast cancer and its clinical significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

Dual effect of erbB-2 depletion on the regulation of DNA repair and cell cycle mechanisms in non-small cell lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

Substrate specificities of caspase family proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

Depletion of Raf-1 protooncogene by geldanamycin causes apoptosis in human luteinized granulosa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

Antitumor activity of curcumin is mediated through the induction of apoptosis in AK-5 tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

MEK inhibition enhances paclitaxel-induced tumor apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101394200

21 January 2018

Identifiers

DOI

10.1074/JBC.M101394200

1 reference

25 November 2017

1 reference