NEET
Lakshya NEET (2025)
                                                      Botany
                                                                                                                DPP: 1
                                      Molecular Basis of Inheritance
Q1 5-methyl uracil is                                             (C) 2                      (D) 1
     (A) Another name of thymine
                                                              Q8 If the length of a DNA molecule is 340 A∘ , then
     (B) A purine base
                                                                   (A) There are 100 nucleotides
     (C) A double ring structure
                                                                   (B) There are 100 base pairs
     (D) Both (A) and (C)
                                                                   (C) There are 100 nitrogenous bases
Q2   5
      ′
          end of a polynucleotide chain contains                   (D) There are 100 sugar phosphates
     (A) Hydroxyl group
                                                              Q9 In    the   polynucleotide      chain     of   DNA,   a
     (B) Ethyl group
                                                                  nitrogenous base is linked to the −OH of
     (C) Carboxyl group
                                                                  (A) 2′ C pentose sugar
     (D) Phosphate group
                                                                  (B) 3′ C pentose sugar
Q3 Variable part of DNA molecule is                               (C) 5′ C pentose sugar
     (A) Phosphate                                                (D) 1′ C pentose sugar
     (B) Sugar
                                                              Q10 Histone proteins are rich in
     (C) Nitrogen base
                                                                   (A) Histidine and Arginine
     (D) Both (B) and (C)
                                                                   (B) Histidne and Lysine
Q4 Nucleotide pairs present in one turn of DNA                     (C) Histidine, arginine and lysine
     helix are                                                     (D) Arginine and Lysine
     (A) 20                   (B) 8
                                                              Q11 The 'beads on string' structure which is seen
     (C) 10                   (D) 9
                                                                   under EM are
Q5 Who proposed central dogma?                                     (A) Histone octamer
     (A) Watson and Crick                                          (B) Nucleosome
     (B) Beadle and Tatum                                          (C) Chromatin
     (C) Klug                                                      (D) Chromatin fibres
     (D) Crick
                                                              Q12 DNA is acidic due to
Q6 Information flow or central dogma of modern                     (A) Sugar
     biology is                                                    (B) Purine
     (A) RNA − Proteins − DNA                                      (C) Phosphate group
     (B) DNA − Proteins − RNA                                      (D) Pyrimidine
     (C) RNA − DNA − Proteins
                                                              Q13 Chromatin is chemically made of
     (D) DNA − RNA − Proteins
                                                                   (A) Nucleic   acid,    histone    and    non-histone
Q7 Number of hydrogen bonds between         A   and   T               proteins
     of DNA is                                                     (B) Nucleic acid and histone proteins only
     (A) 4                    (B) 3                                (C) Nucleic acid and non-histone proteins only
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     (D) Nucleic acid only
Q14 Which        is    the   transcriptionally                 inactive
     chromatin?
     (A) Euchromatin
     (B) Heterochromatin
     (C) Loosely packed chromatin
     (D) Both (B) and (C)
Q15 Number        of    histone    molecules              in     each
     nucleosome core is
     (A) 14                       (B) 12
     (C) 10                       (D) 8
Q16 Nucleosome is
     (A) Intron interrupted DNA
     (B) Double helix DNA
     (C) Negatively charged DNA wrapped around
         positively charged histone octamer
     (D) Satellite DNAs
Q17 If the distance between two consecutive base
     pairs    0.34 nm   and the total number of base
     pairs of DNA double helix in a typical
     mammalian cell is       6.6×         10
                                               9
                                                   bp   . Then the
     length of the DNA is approximately
     (A) 2.5 m
     (B) 2.2 m
     (C) 2.7 m
     (D) 2.0 m
Q18 Which is the transcriptionally active chromatin?
     (A) Euchromatin
     (B) Heterochromatin
     (C) Tightly packed chromatin
     (D) Both (B) and (C)
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                  Answer Key
Q1   (A)                     Q10     (D)
Q2   (D)                     Q11     (B)
Q3   (C)                     Q12     (C)
Q4   (C)                     Q13     (A)
Q5   (D)                     Q14     (B)
Q6   (D)                     Q15     (D)
Q7   (C)                     Q16     (C)
Q8   (B)                     Q17     (B)
Q9   (D)                     Q18     (A)
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                                                                                                                              NEET
                                            Lakshya NEET (2025)
                                                             Botany
                                                                                                                         DPP: 2
                                          Molecular Basis of Inheritance
Q1 Stability as one of the properties of genetic                     Q6   P
                                                                              32
                                                                                   was used to culture bacteriophages in
    material was very evident in                                          Hershey and Chase experiments, that resulted
    (A) Griffith's transforming principle                                 in radioactive
    (B) Hershey and Chase experiment                                      (A) Viral DNA
    (C) Meselson & Stahl's centrifugation technique                       (B) Bacterial capsule
    (D) Taylor's experiment                                               (C) Viral proteins
                                                                          (D) Plasma membrane of bacteria
Q2 Biochemical nature of genetic material was not
    defined from                                                     Q7 RNA possess additional .....................group at
    (A) Transforming principle                                            ...................position in the sugar than the DNA.
    (B) Hershey and Chase experiment                                      (A) OH, 3′
    (C) Avery, Macleod and McCarty                                        (B) H, 2′
    (D) None of the above                                                 (C) OH, 2′
                                                                          (D) H, 3′
Q3 Bacteriophage with radioactivity both in DNA
    and protein infects a bacterium. Bacterium                       Q8 The final proof for DNA as the genetic material
    becomes radioactive. Radioactivity occurs in                          came from the experiments of?
    (A) Protein                                                           (A) Griffith
    (B) DNA                                                               (B) Hershey and Chase
    (C) All parts                                                         (C) Avery, MacLeod and McCarty
    (D) Both (A) and (B)                                                  (D) Har Gobind Khorana
Q4 RNA      is    less   stable   genetic       material    as       Q9 Select correct order from given statements
    compared to DNA. The reason for this is
    (A) In RNA, 2' position has -          OH     group while
       DNA does not
    (B) RNA is also known to be catalytic
    (C) RNA has uracil while DNA has thymine
    (D) All of the above
Q5 During        infection   of   E   .    coli     cells   by
    bacteriophage T2
    (A) Proteins are the only phage components
       that actually enter the infected cell.                             (A) (A)                      (B) (B)
    (B) Both proteins and nucleic acids enter the                         (C) (C)                      (D) (D)
       cell.
    (C) Only proteins from the infecting phage can                   Q10 The             result      of          the      following
        also be detected in progeny phage.                                 reaction/experiment carried out by Avery et. al.
    (D) Only nucleic acids enter the cell.
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on Streptococcus pneumoniae has proved                  (C) Live R-strain + Denatured DNA of S-strain +
conclusively that DNA is the genetic material               Protease
(A) Live R-strain + DNA from S-strain + RNAse           (D) Heat Killed R-strain + DNA from S-strain +
(B) Live R-strain + DNA from S-strain + DNAse               DNAse
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                  Answer Key
Q1   (A)                     Q6      (A)
Q2   (A)                     Q7      (C)
Q3   (B)                     Q8      (B)
Q4   (D)                     Q9      (C)
Q5   (D)                     Q10     (B)
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                                                                                                                 NEET
                                           Lakshya NEET (2025)
                                                         Botany
                                                                                                              DPP: 3
                                      Molecular Basis of Inheritance
Q1 DNA         replication      is    semi-conservative              (C) N14 & N15
    in prokaryotes proved by?                                        (D) C14 &P31
    (A) Meselson and Stahl.
                                                                 Q6 In Meselson and Stahl's experiment using E.coli
    (B) Taylor.
                                                                     culture, the duration between the appearance
    (C) Jacob and Monod.
                                                                     of equal amounts of light and hybrid DNA was:
    (D) A. Kornberg.
                                                                     I. Two generations
Q2 Which statement is incorrect?                                     II. 40 Minutes
    (A) DNA replication is the process by which DNA                  III. 20 Minutes
       makes a copy of itself during cell division.                  IV. 3 generations
               st
    (B) The 1        step in DNA replication is to 'Unzip'           (A) I and II            (B) II and III
       the double helix structure of the DNA                         (C) III and IV          (D) I and IV
       molecule.
                                                                 Q7 During DNA replication, synthesis of leading
    (C) DNA replication occur in all living organisms.
                                                                     and lagging strand require?
    (D) DNA replication is a process during this
                                                                     (A) Single primer
        process DNA is catalyses by enzyme to form
                                                                     (B) Single and many primers respectively
        the 3 copies of DNA segment in which two
                                                                     (C) Many and single primers respectively
        are new strands while one is older.
                                                                     (D) Many primers
Q3 DNA polymerisation rate of DNA polymerase is
                                                                 Q8 Enzyme            DNA   polymerase        catalyse
    (A) 3.9 × 107 bp
                                                                     polymerisation in
    (B) 2000bp/s
                                                                     (A) Ribonucleotides
    (C) 4.6 × 106 bp
                                                                     (B) 5'-3' direction
    (D) 5000bp/s
                                                                     (C) 3'-5' direction
Q4 Strand separation due to breaking the H -                         (D) Deoxyribonucleosides
    bonds in DNA replication is done by
                                                                 Q9 During polymerization of deoxyribonucleosides
    (A) Topoisomerase            (B) DNA Polymerase
                                                                     triphosphates in bacteria which of the following
    (C) Helicase                 (D) Gyrase
                                                                     enzyme is mainly required?
Q5 Isotopes used for experimental proof of DNA                       (A) DNA dependent RNA polymerase.
    replication are                                                  (B) DNA dependent DNA polymerase.
          14        13
    (A) N &P                                                         (C) RNA dependent DNA polymerase.
          14        14
    (B) N &C                                                         (D) DNA gyrase.
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                  Answer Key
Q1   (A)                     Q6      (A)
Q2   (D)                     Q7      (B)
Q3   (B)                     Q8      (B)
Q4   (C)                     Q9      (B)
Q5   (C)
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                                                                                                                 NEET
                                           Lakshya NEET (2025)
                                                     Botany
                                                                                                            DPP: 4
                                   Molecular Basis of Inheritance
Q1 Select the correct option from the given                   III. Promoter
    statements-                                               IV. Structural gene
    (1) r-RNA provides the template for synthesis             V. terminator
    of proteins.                                              VI. Cistron
    (2) t-RNA brings amino acids and reads the                (A) I, II and III
    genetic code.                                             (B) II, III and IV
    (3) RNA polymerase binds to promoter and                  (C) III, IV and V
    initiates transcription.                                  (D) IV, V and VI
    (4) A segment of DNA coding for polypeptide is
                                                          Q6 Monocistronic transcriptional unit codes for
    called intron.
                                                              (A) single polypeptide
    (A) 1 and 3 are correct.
                                                              (B) double polypeptides
    (B) 1 and 2 are correct.
                                                              (C) no polypeptide
    (C) 1, 2 and 3 are correct.
                                                              (D) triple polypeptides
    (D) 2 and 3 are correct
                                                          Q7 During transcription, the site of DNA molecule
Q2 Which one of the following is not applicable to
                                                              at which RNA polymerase binds is called
    RNA?
                                                              (A) Promoter                  (B) Regulator
    (A) Chargaff's rule.
                                                              (C) Receptor                  (D) Enhancer
    (B) Complementary base pairing.
    (C) 5' phosphoryl and 3' hydroxyl ends.               Q8 The structural genes, in eukaryotes possess
    (D) Heterocyclic nitrogenous bases.                       coding and non-coding sequences called
                                                              as______                                             (i)
Q3 Portion of DNA having information for an
                                                              ______and_____(ii)_____respectively.
    entire polypeptide/trait is
                                                              (A) (i) promoter, (ii) operator
    (A) Cistron                (B) Recon
                                                              (B) (i) introns, (ii) exons
    (C) Muton                  (D) Operon
                                                              (C) (i) exons, (ii) introns
Q4 The promoter site and the terminator site                  (D) (i) enhancer, (ii) silencer
    for transcription are located at
                                                          Q9 Ribosomal RNA is synthesized in
    (A) 3' (downstream) and 5' (upstream) end,
                                                              (A) Nucleolus                 (B) Nucleosome
        respectively of the transcription unit
                                                              (C) Ribosome                  (D) Lysosome
    (B) 5' (upstream) end and 3' (downstream) end,
        respectively of the transcription unit            Q10 Methyl guanosine triphosphate is added at 5′
    (C) The 5' (upstream) end                                  end of hnRNA in a process of
    (D) The 3' (downstream) end                                (A) Tailing                   (B) Splicing
                                                               (C) Capping                   (D) None of these
Q5 Regions of transcription units are-
    I. Exon.                                              Q11 snRNAs are transcribed with the help of
    II. Intron
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     (A) RNA polymerase I
     (B) RNA polymerase I and II
     (C) RNA polymerase II
     (D) RNA polymerase III
Q12 RNA polymerase III transcribes
     (A) tRNA
     (B) ssDNA
     (C) mRNA
     (D) Reverse transcriptase
Q13 Find out A-E from the given diagram
     A− Promoter site
     B− Structural gene
     C− Terminator gene
     D− Template strand
     E− Coding strand
     (A) A-5, B-1,C- 4,D-2, E-3
     (B) A-5,B-1,C- 4, D-3, E-2
     (C) A-5,B-4,C- 1,D-2, E-3
     (D) A-1,B-4,C- 5, D-2, E-3
Q14 How many adenylate residues are added at 3′
     end of hn RNA?
     (A) 300 − 400            (B) 200 − 300
     (C) 400 − 500            (D) 100 − 200
Q15 During transcription, if the nucleotide sequence
     of the DNA strand that is being coded is
     ATACG, then the nucleotide sequence in the
     mRNA would be
     (A) TATGC                (B) TCTGG
     (C) UAUGC                (D) UATGC
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                  Answer Key
Q1   (D)                     Q9      (A)
Q2   (A)                     Q10     (C)
Q3   (A)                     Q11     (D)
Q4   (B)                     Q12     (A)
Q5   (C)                     Q13     (C)
Q6   (A)                     Q14     (B)
Q7   (A)                     Q15     (C)
Q8   (C)
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                                                                                                                      NEET
                                            Lakshya NEET (2025)
                                                         Botany
                                                                                                               DPP: 5
                                      Molecular Basis of Inheritance
Q1 Which out of the following statements is                     Q8 Dr. Har Gobind Khorana was instrumental
    incorrect?                                                       in     synthesizing       RNA    molecules       with
    (A) Genetic code is ambiguous.                                   defined combinations of
    (B) Genetic code is degenerate.                                  (A) homopolymers
    (C) Genetic code is universal.                                   (B) heteropolymers
    (D) Genetic code is non-overlapping.                             (C) Homopolymer and copolymer
                                                                     (D) hetero-Oligomers
Q2 Out of 64 codons, 61 code for 20 types of amino
    acids. This property of genetic code is called as           Q9 Untranslated regions are present at ............
    (A) Unambiguous nature of code                                   (A) After 5′ end
    (B) Degeneracy of genetic code                                   (B) Before 5′ end
    (C) Wobbling of codons                                           (C) 5′ end (after start codon) and at 3′ end
    (D) Universality of codons                                            (before stop codon)
                                                                     (D) 5′ end (before start codon) and at 3′ end
Q3 Which one is not a termination codon?
                                                                          (after stop codon)
    (A) UAA                      (B) UAG
    (C) AUG                      (D) UGA                        Q10 Identify the process associated with the
                                                                      synthesis of enzymes and proteins.
Q4 From bacteria to men, a near universal code for
                                                                      (A) Translation            (B) Replication
    phenylalanine
                                                                      (C) Transduction           (D) Transcription
    (A) UUU                      (B) UUA
    (C) UUG                      (D) CUU                        Q11 Charging (Aminoacylation) of tRNA involves the
                                                                     attachment of
Q5 Which of the following has dual functions?
                                                                     (A) Amino acid to mRNA
    (A) AUG                      (B) AUC
                                                                     (B) amino acid to tRNA
    (C) ACU                      (D) ACA
                                                                     (C) amino acid to rRNA
Q6 Three dimensional shape of tRNA is                                (D) acidic acid to ribosome
    (A) Inverted L-shaped
                                                                Q12 Amino acids are activated by
    (B) Clover leaf-like
                                                                      (A) ADP
    (C) X-shaped
                                                                      (B) AMP
    (D) Y-shaped
                                                                      (C) ATP
Q7 For 50 amino acids in a polypeptide chain,                         (D) Special proteins
    what      will   be    the   minimum      number   of
                                                                Q13 Proteins are formed by
    nucleotides in its cistron?
                                                                      (A) peptide link
    (A) 50                       (B) 153
                                                                      (B) glycosidic link
    (C) 306                      (D) 300
                                                                      (C) phosphate link
                                                                      (D) phosphodiamine linkage
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                  Answer Key
Q1   (A)                     Q8      (C)
Q2   (B)                     Q9      (D)
Q3   (C)                     Q10     (A)
Q4   (A)                     Q11     (B)
Q5   (A)                     Q12     (C)
Q6   (A)                     Q13     (A)
Q7   (B)
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                                                                                                                 NEET
                                            Lakshya NEET (2025)
                                                         Botany
                                                                                                             DPP: 6
                                       Molecular Basis of Inheritance
Q1 In lac peron, the genes a, i, y and z code                     Q5 Match the following columns select correct
    respectively for?                                                option
    (A) Repressor          protein,     permease,      β-
          galactosidase, transacetylase.
    (B) Transacetylase, permease, β -galactosidase,
          repressor protein.
    (C) β -galactosidase, transacetylase, repressor
          protein, permease.
    (D)       Transacetylase,         repressor   protein,
          permease, β -galactosidase.
Q2 Match the following columns.                                      (A) A-2, B-5, C-1, D-3
                                                                     (B) A-3, B-4, C-5, D-1
                                                                     (C) A-4, B-1, C-5, D-2
                                                                     (D) A-5, B-4, C-2, D-1
                                                                 Q6 Identify components and enzymes for the
                                                                     given figure
    (A) I-4, II-1, III-2
    (B) I-2, II-3, III-1
    (C) I-2, II-1, III-3
    (D) I-3, II-2, III-1
Q3 The sequence of structural gene in lac operon
    concept is?                                                      (A) X-Repressor protein, Y- Inducer (lactose), E1
    (A) Lac A, Lac Y, Lac Z.                                             - Permease, E2 - Transacetylase, E3 − β
    (B) Lac A, Lac Z, Lac Y.                                             galactosidase.
    (C) Lac Y, Lac Z, Lac A.                                         (B) X-Repressor protein, Y-Inducer (lactose),
    (D) Lac Z, Lac Y, Lac A.                                             E1 − β-galactosidase,        E2             -
                                                                         Transacetylase, E3 Permease.
Q4 In lac operon, the structural genes are switches
                                                                     (C) X-Inducer (lactose), Y-Repressor protein, E1-
    off when
                                                                         β - galactosidase, E2 - Permease, E3
    (A) Repressor binds to operator.
                                                                         Transacetylase.
    (B) Repressor binds to promoter.
                                                                     (D) X-Repressor protein, Y- Inducer (lactose), E1-
    (C) Repressor binds to regulator.
                                                                         β - galactosidase, E2 - Permease, E3
    (D) Repressor binds to inducer.
                                                                         Transacetylase.
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Q7 Which of the following is required as inducer for
    the expression of lac operon?
    (A) Glucose
    (B) Galactose
    (C) Lactose
    (D) Lactose and Galactose
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                  Answer Key
Q1   (D)                     Q5      (C)
Q2   (A)                     Q6      (D)
Q3   (D)                     Q7      (C)
Q4   (A)
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                                                                                                             NEET
                                      Lakshya NEET (2025)
                                                      Botany
                                                                                                          DPP: 7
                                 Molecular Basis of Inheritance
Q1 Transfer of DNA from an agarose gel to a                    (D) None of the above
    nitrocellulose or nylon membrane is referred to
                                                           Q6 ____________is also credited for developing
    (A) Western transfer
                                                               method for determination of amino acid
    (B) Northern transfer
                                                               sequences in proteins.
    (C) Eastern transfer
                                                               (A) Frederick Sanger
    (D) Southern transfer
                                                               (B) Alec Jeffreys
Q2 The main aim of the human genome project is                 (C) J.D. Watson
    (A) To introduce new genes into humans.                    (D) Sydney Brenner
    (B) To identify and sequence all the genes
                                                           Q7 Father of DNA fingerprinting is?
       present in human DNA.
                                                               (A) Alec Jeffreys        (B) Lalji Singh
    (C) To develop better techniques for comparing
                                                               (C) V.K. Kashyap         (D) E.M. Southern
       two different human DNA samples.
    (D) To remove disease causing genes from               Q8 SNPs or single nucleotide polymorphism is a
       human DNA.                                              (A) location on RNA where a single base differs.
                                                               (B) location on genome where many bases of
Q3 Due to high degree of polymorphism size of
                                                                   DNA differs.
    VNTR varies from
                                                               (C) location on genome where the single base
    (A) 0.1 to 20 kb.
                                                                   of DNA differs.
    (B) 0.1 to 2 kb
                                                               (D) location of enzymes where the single base
    (C) 0.01 to 20 kb
                                                                   differs.
    (D) 0.1 to 200 kb
                                                           Q9 The last human chromosome whose sequence
Q4 Which chromosome have maximum number of
                                                               was completed in may, 2006, is
    genes?
                                                               (A) Chromosome 22.
    (A) Chromosome Y
                                                               (B) Chromosome 14.
    (B) Chromosome X
                                                               (C) Chromosome 1.
    (C) Chromosome number 10
                                                               (D) Chromosome X and Y .
    (D) Chromosome number 1
Q5 Human genome contain ......
    (A) 3 × 108 bp
    (B) 3 × 109 bp
    (C) 3 × 107 bp
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Q10 What percentage of human genome codes for
     proteins?
     (A) 99%
     (B) More than 10%
    (C) Less than 1%
    (D) Less than 2%
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                  Answer Key
Q1   (D)                     Q6      (A)
Q2   (B)                     Q7      (A)
Q3   (A)                     Q8      (C)
Q4   (D)                     Q9      (C)
Q5   (B)                     Q10     (D)
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