MEDIHELP
DRUG OF CHOICE
ANTIBIOTICS
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Introduction
I must emphasize that antibiotic selection and
dosages are highly individualized and should be
determined based on factors such as the type
and severity of infection, patient characteristics,
and local antibiotic resistance patterns.
Pertussis
Azithromycin
Child: 10 mg/kg/dose (maximum 500
mg/dose), once daily, on day one,
followed by 5 mg/kg/dose (maximum 250
mg/dose), once daily, on days two to
five.
Adult: 500 mg, once daily, on day one,
followed by 250 mg, once daily, on days
two to five
Pharyngitis & Tonsillitis
Child: 50 mg/kg/dose (maximum 1 g/dose), once
daily, for ten days; or 25 mg/kg/dose (maximum
500 mg/dose), twice daily, for ten days.
Adult: 1 g, once daily, for ten days; or 500 mg,
twice daily, for ten days
Amoxicillin
Severe bacterial conjunctivitis
Chloramphenicol 0.5% eye drops
Child < 2 years: 1 drop, four times daily, until
48 hours after symptoms have resolved or
five days (whichever is shorter)
Child > 2 years and adult: 1 – 2 drops, every
two to six hours,* until 48 hours after
symptoms have resolved or five days
(whichever is shorter)
Suspected meningococcal
disease
Ceftriaxone
Child < 30kg: 100 mg/kg, (maximum 4
g/dose) stat dose IV (or IM*)
Child > 30kg and Adult: 2 g, stat dose IV
(or IM*)
IV administration is preferred to IM
(where available and not leading to
delays)
Boils (furuncles), carbuncles &
Cellulitis
Flucloxacillin
Child: 12.5 – 25 mg/kg/dose (usually up to
500 mg/dose; maximum 1 g/dose), four times
daily, for five days
Adult: 500 mg – 1 g†, three to four times
daily, for five days
Can be taken with food to minimise
gastrointestinal adverse effects associated
with high doses or to make the suspension
more palatable for children.
Giardiasis
Ornidazole OR Metronidazole
Child < 35 kg: 125 mg/3 kg/dose,* once
daily, for one to two days
Child > 35 kg and Adult: 1.5 g, once daily
in the evening, for one to two days
Dose is per 3 kg bodyweight; ornidazole is
only available in tablet form
Salmonellosis
Ciprofloxacin
Adult: 500 mg, twice daily, for three days
Alternatively
Trimethoprim + sulfamethoxazole
Adult: 960 mg, twice daily, for three days
Prostatitis
Trimethoprim
Adult: 300 mg, once daily, for two to four weeks, if
acute infection, or four to six weeks if chronic
infection
OR
Trimethoprim + sulfamethoxazole
Adult: 960 mg, twice daily, for two to four weeks, if
acute infection, or four to six weeks if chronic
infection
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