- Division of Pediatric Rheumatology, Children's Medical Center, Dr Gharib St., Tehran, Iran
- +98(21)66595522
- Tehran University of Medical Sciences, Sports Medicine Research Center, Faculty Memberadd
Wegener's granulomatosis or granulomatosis polyangiitis (GPA) is an uncommon chronic systemic vasculitis in children. The aim of this study was to describe pediatric patients with GPA in Iran. We studied records of all patients with GPA... more
Wegener's granulomatosis or granulomatosis polyangiitis (GPA) is an uncommon chronic systemic vasculitis in children. The aim of this study was to describe pediatric patients with GPA in Iran. We studied records of all patients with GPA diagnosis who were referred to all Iranian Pediatric Rheumatology Division from 2002 to 2011. A total of 11 patients (5 females and 6 males) enrolled in this study. In children less than 15 years old, the prevalence of GPA is 0.6 per million. The mean age of GPA diagnosis was 11 years and average delay diagnosis was 20 months. Mortality rate was 18.1% due to pulmonary vasculitis and infection. The most common organ system involvement was upper and lower respiratory tract involvement (81.8% and 63.9%, resp.). Other common manifestations were renal (36.3), skin (27.2%), and eye involvement (18.2%).
"Patient: Female, 12 Final Diagnosis: Antiphospholipid positive SLE Symptoms: Gangrene • Raynaud's phenomenon • autoamputation of the terminal phalanx of the second left hand finger Medication: Prednisolone • mycophenolate mofetil •... more
"Patient: Female, 12 Final Diagnosis: Antiphospholipid positive SLE Symptoms: Gangrene • Raynaud's phenomenon • autoamputation of the terminal phalanx of the second left hand finger Medication: Prednisolone • mycophenolate mofetil • captopril Clinical Procedure: Renal Biopsy • treatment of lupus nephritis • control of hypertension Specialty: Pediatric rheumatology.
OBJECTIVE:
Unusual clinical course.
BACKGROUND:
SLE in children has many manifestations. In several studies on SLE in children, gangrene and Raynaud phenomenon have been described as a rare manifestation of SLE during its course in children.
CASE REPORT:
We present the case of a 12-year-old girl referred to our center, presenting with peripheral gangrene plus Raynaud's phenomenon, who proved to have SLE. Our patient was treated with steroids and mycophenolate mofetil. She appeared to respond to this combination judging by the disappearance of the digital cyanosis, appearance of extremity pulses, and return of renal function.
CONCLUSIONS:
This case highlights the importance of precise management and awareness of very rare manifestations of a common disease like SLE. Gangrene can be initial symptom of SLE in children. We recommend SLE evolution in all children with gangrene symptom.
KEYWORDS:
Raynaud phenomenon, children, gangrene, systemic lupus erythematosus""
OBJECTIVE:
Unusual clinical course.
BACKGROUND:
SLE in children has many manifestations. In several studies on SLE in children, gangrene and Raynaud phenomenon have been described as a rare manifestation of SLE during its course in children.
CASE REPORT:
We present the case of a 12-year-old girl referred to our center, presenting with peripheral gangrene plus Raynaud's phenomenon, who proved to have SLE. Our patient was treated with steroids and mycophenolate mofetil. She appeared to respond to this combination judging by the disappearance of the digital cyanosis, appearance of extremity pulses, and return of renal function.
CONCLUSIONS:
This case highlights the importance of precise management and awareness of very rare manifestations of a common disease like SLE. Gangrene can be initial symptom of SLE in children. We recommend SLE evolution in all children with gangrene symptom.
KEYWORDS:
Raynaud phenomenon, children, gangrene, systemic lupus erythematosus""
Page 1. 1 : : – – : ir.ac.tums ziaee@ Page 2. 2 Evaluating sport injuries in students' football plays Dr.V.Ziaee, Dr.R.Kordi, Dr.F.Halabchi, Dr.SRReiskarami, Dr.M.Iranshahi Abstract: Objective: Football players are exposed to a high risk... more
Page 1. 1 : : – – : ir.ac.tums ziaee@ Page 2. 2 Evaluating sport injuries in students' football plays Dr.V.Ziaee, Dr.R.Kordi, Dr.F.Halabchi, Dr.SRReiskarami, Dr.M.Iranshahi Abstract: Objective: Football players are exposed to a high risk of injury. We designed this study to determine the frequency and severity of injury in student's football. Subjects & method: By a descriptive study over football players that attended in 4 th students sport Olympiad (in 1379) the incidence of injury among was evaluated.
Purpose: The aim of this study was to examine the influence of selected exercises on motor development in elementary school third grade girl students in Ahwaz City, Iran. Methods: The present study was semi-experimental, performed as... more
Purpose: The aim of this study was to examine the influence of selected exercises on motor development in elementary school third grade girl students in Ahwaz City, Iran. Methods: The present study was semi-experimental, performed as field and using experimental and control groups. The statistical population included all third grade girl students of elementary schools of Ahvaz city (10,500 subjects).
Objective: The aim of this study was to evaluate the bilirubin albumin (B/A) ratio in comparison with total serum bilirubin (TSB) for predicting acute bilirubin-induced neurologic dysfunction (BIND). Methods: Fifty two term and near term... more
Objective: The aim of this study was to evaluate the bilirubin albumin (B/A) ratio in comparison with total serum bilirubin (TSB) for predicting acute bilirubin-induced neurologic dysfunction (BIND). Methods: Fifty two term and near term neonates requiring phototherapy and exchange transfusion for severe hyperbilirubinemia in Children's Medical Center, Tehran, Iran, during September 2007 to September 2008, were evaluated. Serum albumin and bilirubin were measured at admission.
Abstract: A number of studies have examined the role of aerobic exercise and evidence suggests this may be an effective therapy for premenstrual syndrome (PMS). The aim of this study was to assess the PMS symptoms between swimmer and... more
Abstract: A number of studies have examined the role of aerobic exercise and evidence suggests this may be an effective therapy for premenstrual syndrome (PMS). The aim of this study was to assess the PMS symptoms between swimmer and non-swimmer female students. Two hundred eighty subjects were studied. One hundred forty subjects were swimmers, while 140 were normal sedentary controls. Duration of swimming per week, and the length of exercise were asked from the case group.
Purpose: Despite numerous studies which have been done regarding soccer injuries worldwide, there is lack of available data considering the epidemiology of injuries in the Iranian soccer premier league, although it is the most popular... more
Purpose: Despite numerous studies which have been done regarding soccer injuries worldwide, there is lack of available data considering the epidemiology of injuries in the Iranian soccer premier league, although it is the most popular sport in the country. The main goal of this research was to determine the incidence of physical injuries in the studied population, considering other characteristics such as site, type and mechanism as well.
Background: Both hypoxia and hypocapnia can cause broncho-constriction in humans, and this could have a bearing on performance at high altitude. The objective of this study was to examine how pulmonary ventilatory function during... more
Background: Both hypoxia and hypocapnia can cause broncho-constriction in humans, and this could have a bearing on performance at high altitude. The objective of this study was to examine how pulmonary ventilatory function during high-altitude trekking. Methods: This study was a before and after study on spirometric parameters at Base line (1150 m above sea level), and after ascending at 4150 m above sea level. This study was performed in summer 2004 at Cialan Mountain in Iran.
ABSTRACT Introduction: Female adolescents and adults are among the population groups who are most affected by iron deficiency. Thus, the aim of this study was to investigate the prevalence of iron deficiency and iron deficiency anaemia in... more
ABSTRACT Introduction: Female adolescents and adults are among the population groups who are most affected by iron deficiency. Thus, the aim of this study was to investigate the prevalence of iron deficiency and iron deficiency anaemia in female students aged 18 to 25 years old from the Tehran University of Medical Sciences, Iran.
Background: We performed this study considering the fact that many chronic diseases have their origin in early life, their risk factors in childhood and adulthood are identical, and an early primary prevention is of great importance.... more
Background: We performed this study considering the fact that many chronic diseases have their origin in early life, their risk factors in childhood and adulthood are identical, and an early primary prevention is of great importance. Methods: The present national survey was performed as a multi-centric cross-sectional study for the baseline survey of a project entitled: Childhood and Adolescence Surveillance and PreventIon of Adult Non-communicable Diseases: CASPIAN Study.
Background: Sedentary behavior in childhood is one of the strongest risk factors for many chronic diseases and somatic conditions in adulthood, including cardiovascular disease, hypertension, obesity, and osteoporosis. This study was an... more
Background: Sedentary behavior in childhood is one of the strongest risk factors for many chronic diseases and somatic conditions in adulthood, including cardiovascular disease, hypertension, obesity, and osteoporosis. This study was an investigation to design a surveillance system for non-communicable diseases.
Research Interests: Psychology, Autism, Developing Countries, Adolescent, Comorbidity, and 16 moreIran, Medical History, Cultural Differences, Humans, Child, Developing Country, Female, Male, Cross cultural studies, Developmental disabilities, Autism Spectrum Disorder, Children and Adolescents, Prevalence, Public health systems and services research, Drug Costs, and Psychotropic Drugs
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Research Interests: Psychology, Nursing, Adolescent, Comorbidity, Iran, and 5 moreHumans, Child, Female, Male, and School health services
PurposeHeadache at altitudes has had an incidence of 25-62% through many related studies. Many reasons are identified concerning headache at altitudes such as acute mountain sickness (AMS), sinus headache, migraine, tension type headache,... more
PurposeHeadache at altitudes has had an incidence of 25-62% through many related studies. Many reasons are identified concerning headache at altitudes such as acute mountain sickness (AMS), sinus headache, migraine, tension type headache, and frontal tension headache. This study tried to compare different types of headache among trekkers on Mount Damavand, a 5671m mountain, Iran, to find their incidence and related symptoms and signs.MethodsThrough a cross-sectional study, we evaluated headache incidence and its correlation to AMS among people who climbed Mount Damavand. Lake Louise Score, a self-report questionnaire, was applied to make AMS diagnosis through three separate stages of trekking programs. Chi-square test was employed as the main mean of analysis.ResultsTotally, 459 between 13-71 year olds participated in the study among which females were 148 (32.1%) and males 311 (67.8%). Headache was found in 398 (86.7%) among whom 279 (70%) were proved as AMS. Investigating the types of headache in the cases of AMS showed 64.5% to be of steady, 31% throbbing and 4.5% stabbing characters which had significant differences with a P value = 0.003. The majority of headaches were stated as frontal (38.9%) and the least prevalence belonged to the parietal area (4.4%), while global headache was reported in 27%.ConclusionsThis study specifies the exact location of headaches at altitude in cases of AMS and non-AMS headaches. Many cases of high altitude non-AMS headache are resulted by tension and light reflection at altitude.
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Abstract Infectious diseases are an increasing global health problem. Comparative studies about vaccination behavior in health care students from different countries are lacking. Due to working close to patients and infected specimens,... more
Abstract Infectious diseases are an increasing global health problem. Comparative studies about vaccination behavior in health care students from different countries are lacking. Due to working close to patients and infected specimens, they are in risk of contracting infectious diseases. The study analyzed vaccinations in health care students against tetanus, diphtheria, poliomyelitis, measles, mumps, rubella and hepatitis A+ B. Furthermore, the study tried to investigate assessments on the importance of vaccinations and possible ...
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Introduction. Clinical education is a process by which students obtain clinical experiences and ideas on the patients' bedside to be prepared for patient's problem solving. Continuous evaluation... more
Introduction. Clinical education is a process by which students obtain clinical experiences and ideas on the patients' bedside to be prepared for patient's problem solving. Continuous evaluation and identification of strengths and weaknesses of this process by different methods is necessary for development of an effective medical education and assessment of student satisfaction (SS) is one of the best methods. Thus for determining the SS of clinical education in a group of medical students we designed this study. Methods. We designed a ...
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To examine the effectiveness of parental support and involvement in a low-cost intervention for the improvement of health-related fitness of high school girls through an after-school physical activity (PA) program. This multi-site study... more
To examine the effectiveness of parental support and involvement in a low-cost intervention for the improvement of health-related fitness of high school girls through an after-school physical activity (PA) program. This multi-site study was conducted in 2006-2007 in 7 provinces in Iran. The study population comprised of two groups of children. The first group consisted of 206 children who were randomly selected from female students (7th-10th grade) and their mothers (n=204). Another 60 children (without their mothers) were randomly selected as the control group. Overall, during 12 weeks, 24 sessions of after-school aerobic exercise were held. Health-related fitness data were collected pre- and post-intervention. The findings are based on 470 participants. The after-school PA significantly improved body mass index, resting heart rate, cardiorespiratory fitness, flexibility and muscle strength and endurance in children in both groups, and in mothers. Improvement in the physiological measures of the children in the mother/daughter group was significantly better than the control group. The findings suggest that after-school PA may provide an effective model for improving the health-related fitness of high school girls and their mothers. Our data show that family support, including mother's participation, contributes to enhanced health-related achievements in adolescent girls.
Research Interests: Physical Activity, Preventive medicine, Health, Adolescent, Fitness, and 17 moreMuscle strength, Schools, Humans, Female, Recreational Activities, Heart rate, Heart, Muscles, Exercise, Mothers, Body Mass Index, Physical Fitness, Cardiovascular system, Public health systems and services research, Curriculum and Pedagogy, Preventive, and Physical Education and training
To provide a low-cost and simple model of culturally-appropriate and low cost facilities for improvement of physical activity for girls and their mothers through an after-school program and to determine the changes in anthropometric... more
To provide a low-cost and simple model of culturally-appropriate and low cost facilities for improvement of physical activity for girls and their mothers through an after-school program and to determine the changes in anthropometric indexes after this trial. This national study was conducted in 2006-2007 in 7 provinces with different socioeconomic situations in Iran. Female students who studied in the 7(th) through 10(th) grade and their mothers were selected by random cluster sampling. In each province, 24 sessions of after-school aerobic physical activity were held for 90 minutes, two days a week, and 3 months long at school sites in the afternoon. The study comprised 410 participants (204 mothers and 206 daughters), with a mean age of 15.86±1.01 and 40.71±6.3 years in girls and their mothers, respectively. The results of the focus group discussions showed that in general, both mothers and daughters were satisfied from the program and found it feasible and successful. After the trial, the indexes of generalized and abdominal obesity improved significantly both in girls and in their mothers (P-value <0.0001 for weight, body mass index and waist circumference). Our findings may provide a low-cost and simple effective model of motivation for physical activity with targeted interventions for girls and their mothers. We suggest that the success of this trial might be a result of bonding and accompaniment of mothers and daughters. Such model can be integrated in the existing health and education systems to increase the physical activity level.