"Endothelins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
21-Amino-acid peptides produced by vascular endothelial cells and functioning as potent vasoconstrictors. The endothelin family consists of three members, ENDOTHELIN-1; ENDOTHELIN-2; and ENDOTHELIN-3. All three peptides contain 21 amino acids, but vary in amino acid composition. The three peptides produce vasoconstrictor and pressor responses in various parts of the body. However, the quantitative profiles of the pharmacological activities are considerably different among the three isopeptides.
| Descriptor ID |
D016232
|
| MeSH Number(s) |
D12.644.276.400 D12.776.467.400 D23.529.400
|
| Concept/Terms |
Endothelins- Endothelins
- Endothelium-Derived Vasoconstrictor Factors
- Vasoconstrictor Factors, Endothelium-Derived
- Endothelin
|
Below are MeSH descriptors whose meaning is more general than "Endothelins".
Below are MeSH descriptors whose meaning is more specific than "Endothelins".
This graph shows the total number of publications written about "Endothelins" by people in this website by year, and whether "Endothelins" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 5 | 5 | 10 |
| 1996 | 1 | 5 | 6 |
| 1997 | 2 | 0 | 2 |
| 1998 | 3 | 1 | 4 |
| 1999 | 0 | 2 | 2 |
| 2000 | 1 | 0 | 1 |
| 2001 | 0 | 3 | 3 |
| 2002 | 6 | 6 | 12 |
| 2003 | 2 | 3 | 5 |
| 2004 | 1 | 3 | 4 |
| 2005 | 2 | 0 | 2 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 2 | 2 |
| 2010 | 1 | 1 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 3 | 0 | 3 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2018 | 0 | 2 | 2 |
| 2019 | 1 | 1 | 2 |
| 2020 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
Below are the most recent publications written about "Endothelins" by people in Profiles.
-
The Role of the Endocrine System in the Regulation of Acid-Base Balance by the Kidney and the Progression of Chronic Kidney Disease. Int J Mol Sci. 2024 Feb 19; 25(4).
-
Endothelial contraction of retinal veins. Exp Eye Res. 2023 03; 228:109386.
-
Trans women have worse cardiovascular biomarker profiles than cisgender men independent of hormone use and HIV serostatus. AIDS. 2022 11 01; 36(13):1801-1809.
-
Targeting the endothelin axis as a therapeutic strategy for oral cancer metastasis and pain. Sci Rep. 2020 11 30; 10(1):20832.
-
Endothelial Responses in Sepsis. Am J Respir Crit Care Med. 2020 08 01; 202(3):361-370.
-
Role of NO and other vascular mediators in the etiopathogenesis of necrotizing enterocolitis. Front Biosci (Schol Ed). 2019 03 01; 11(1):9-28.
-
Venous endothelin modulates responsiveness of cardiac sympathetic axons to arterial semaphorin. Elife. 2019 02 08; 8.
-
TWISTed HIF: revisiting smooth muscle HIF-1α signaling in pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2018 09 01; 315(3):L387-L389.
-
Retarding progression of chronic kidney disease: use of modalities that counter acid retention. Curr Opin Nephrol Hypertens. 2018 03; 27(2):94-101.
-
Inhibition of agonist-induced smooth muscle contraction by picotamide in the male human lower urinary tract outflow region. Eur J Pharmacol. 2017 May 15; 803:39-47.