"Endothelin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (N Eng J Med 1995;333(6):356-63)
| Descriptor ID |
D019332
|
| MeSH Number(s) |
D12.644.276.400.225 D12.776.467.400.225 D23.529.400.225
|
| Concept/Terms |
Proendothelin (1-38)- Proendothelin (1-38)
- Big Endothelin
- Big Endothelin-1
- Big Endothelin 1
- Endothelin-1, Big
- Endothelin, Big
Preproendothelin-1- Preproendothelin-1
- Preproendothelin 1
- Preproendothelin
- Proendothelin-1 Precursor
- Precursor, Proendothelin-1
- Proendothelin 1 Precursor
|
Below are MeSH descriptors whose meaning is more general than "Endothelin-1".
Below are MeSH descriptors whose meaning is more specific than "Endothelin-1".
This graph shows the total number of publications written about "Endothelin-1" by people in this website by year, and whether "Endothelin-1" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 3 | 0 | 3 |
| 1997 | 6 | 3 | 9 |
| 1998 | 5 | 2 | 7 |
| 1999 | 4 | 3 | 7 |
| 2000 | 10 | 5 | 15 |
| 2001 | 4 | 2 | 6 |
| 2002 | 7 | 2 | 9 |
| 2003 | 9 | 7 | 16 |
| 2004 | 8 | 7 | 15 |
| 2005 | 10 | 7 | 17 |
| 2006 | 9 | 3 | 12 |
| 2007 | 7 | 4 | 11 |
| 2008 | 4 | 10 | 14 |
| 2009 | 8 | 5 | 13 |
| 2010 | 4 | 3 | 7 |
| 2011 | 7 | 7 | 14 |
| 2012 | 1 | 4 | 5 |
| 2013 | 4 | 3 | 7 |
| 2014 | 7 | 1 | 8 |
| 2015 | 5 | 5 | 10 |
| 2016 | 5 | 0 | 5 |
| 2017 | 2 | 4 | 6 |
| 2018 | 2 | 2 | 4 |
| 2019 | 2 | 1 | 3 |
| 2020 | 1 | 2 | 3 |
| 2021 | 0 | 1 | 1 |
| 2022 | 2 | 1 | 3 |
| 2023 | 1 | 1 | 2 |
| 2024 | 1 | 1 | 2 |
Below are the most recent publications written about "Endothelin-1" by people in Profiles.
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A Reduction in Mitophagy Is Associated with Glaucomatous Neurodegeneration in Rodent Models of Glaucoma. Int J Mol Sci. 2024 Dec 04; 25(23).
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Sparsentan improves glomerular hemodynamics, cell functions, and tissue repair in a mouse model of FSGS. JCI Insight. 2024 Sep 03; 9(19).
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Endothelin-1 acutely increases nitric oxide production via the calcineurin mediated dephosphorylation of Caveolin-1. Nitric Oxide. 2023 Nov 01; 140-141:50-57.
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Association of blood pressure variability with Endothelin-1 by menopause status among Black women: findings from the Jackson Heart Study. J Hum Hypertens. 2023 08; 37(8):742-745.
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Endothelial contraction of retinal veins. Exp Eye Res. 2023 03; 228:109386.
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Pulmonary Function Trajectories in People with HIV: Analysis of the Pittsburgh HIV Lung Cohort. Ann Am Thorac Soc. 2022 12; 19(12):2013-2020.
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Associations of the vasoactive peptides CT-proET-1 and MR-proADM with incident type 2 diabetes: results from the BiomarCaRE Consortium. Cardiovasc Diabetol. 2022 06 09; 21(1):99.
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Association of C-Terminal Pro-Endothelin-1 with Mortality in the Population-Based KORA F4 Study. Vasc Health Risk Manag. 2022; 18:335-346.
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Metabolic MRI with hyperpolarized [1-13C]pyruvate separates benign oligemia from infarcting penumbra in porcine stroke. J Cereb Blood Flow Metab. 2021 11; 41(11):2916-2927.
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Protease-Activated Receptor-2 Regulates Neuro-Epidermal Communication in Atopic Dermatitis. Front Immunol. 2020; 11:1740.