Platelet-Derived Growth Factor
"Platelet-Derived Growth Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Mitogenic peptide growth hormone carried in the alpha-granules of platelets. It is released when platelets adhere to traumatized tissues. Connective tissue cells near the traumatized region respond by initiating the process of replication.
| Descriptor ID |
D010982
|
| MeSH Number(s) |
D12.644.276.910 D12.776.124.625 D12.776.467.910 D23.529.910
|
| Concept/Terms |
Platelet-Derived Growth Factor- Platelet-Derived Growth Factor
- Factor, Platelet-Derived Growth
- Growth Factor, Platelet-Derived
- Platelet Derived Growth Factor
|
Below are MeSH descriptors whose meaning is more general than "Platelet-Derived Growth Factor".
Below are MeSH descriptors whose meaning is more specific than "Platelet-Derived Growth Factor".
This graph shows the total number of publications written about "Platelet-Derived Growth Factor" by people in this website by year, and whether "Platelet-Derived Growth Factor" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 5 | 7 | 12 |
| 1996 | 5 | 7 | 12 |
| 1997 | 3 | 8 | 11 |
| 1998 | 9 | 7 | 16 |
| 1999 | 2 | 7 | 9 |
| 2000 | 7 | 7 | 14 |
| 2001 | 2 | 10 | 12 |
| 2002 | 6 | 19 | 25 |
| 2003 | 8 | 9 | 17 |
| 2004 | 5 | 8 | 13 |
| 2005 | 3 | 13 | 16 |
| 2006 | 6 | 10 | 16 |
| 2007 | 6 | 8 | 14 |
| 2008 | 5 | 5 | 10 |
| 2009 | 5 | 14 | 19 |
| 2010 | 5 | 6 | 11 |
| 2011 | 2 | 11 | 13 |
| 2012 | 4 | 8 | 12 |
| 2013 | 2 | 10 | 12 |
| 2014 | 5 | 2 | 7 |
| 2015 | 4 | 6 | 10 |
| 2016 | 0 | 5 | 5 |
| 2017 | 3 | 2 | 5 |
| 2018 | 2 | 1 | 3 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 3 | 4 |
| 2021 | 3 | 0 | 3 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
Below are the most recent publications written about "Platelet-Derived Growth Factor" by people in Profiles.
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Vascular architecture regulates mesenchymal stromal cell heterogeneity via P53-PDGF signaling in the mouse incisor. Cell Stem Cell. 2024 Jun 06; 31(6):904-920.e6.
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Regulation of Smooth Muscle Cell Proliferation by Mitochondrial Ca2+ in Type 2 Diabetes. Int J Mol Sci. 2023 Aug 17; 24(16).
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PDGF signaling inhibits mitophagy in glioblastoma stem cells through N6-methyladenosine. Dev Cell. 2022 06 20; 57(12):1466-1481.e6.
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Rare variant analysis of 4241 pulmonary arterial hypertension cases from an international consortium implicates FBLN2, PDGFD, and rare de novo variants in PAH. Genome Med. 2021 05 10; 13(1):80.
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Microglial neuropilin-1 promotes oligodendrocyte expansion during development and remyelination by trans-activating platelet-derived growth factor receptor. Nat Commun. 2021 04 15; 12(1):2265.
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Cancer-associated fibroblast secretion of PDGFC promotes gastrointestinal stromal tumor growth and metastasis. Oncogene. 2021 03; 40(11):1957-1973.
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VER/VEGF receptors regulate AMPA receptor surface levels and glutamatergic behavior. PLoS Genet. 2021 02; 17(2):e1009375.
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Involvement of PDGF-BB and IGF-1 in Activation of Human Schwann Cells by Platelet-Rich Plasma. Plast Reconstr Surg. 2020 12; 146(6):825e-827e.
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Localized inhibition of platelets and platelet derived growth factor by a matrix targeted glycan mimetic significantly attenuates liver fibrosis. Biomaterials. 2021 02; 269:120538.
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Circulating Tumor Cells and Biomarker Modulation with Olaratumab Monotherapy Followed by Olaratumab plus Doxorubicin: Phase Ib Study in Patients with Soft-Tissue Sarcoma. Mol Cancer Ther. 2021 01; 20(1):132-141.