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ZA849319B - New cephalosporins and process for their preparation - Google Patents

New cephalosporins and process for their preparation

Info

Publication number
ZA849319B
ZA849319B ZA849319A ZA849319A ZA849319B ZA 849319 B ZA849319 B ZA 849319B ZA 849319 A ZA849319 A ZA 849319A ZA 849319 A ZA849319 A ZA 849319A ZA 849319 B ZA849319 B ZA 849319B
Authority
ZA
South Africa
Prior art keywords
ring
substituted
membered
alkyl
group
Prior art date
Application number
ZA849319A
Other languages
English (en)
Inventor
Rolf Angerbauer
Michael Boberg
Karl Georg Metzger
Hans-Joachim Zeiler
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA849319B publication Critical patent/ZA849319B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA849319A 1983-11-30 1984-11-29 New cephalosporins and process for their preparation ZA849319B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833343208 DE3343208A1 (de) 1983-11-30 1983-11-30 Neue cephalosporine und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
ZA849319B true ZA849319B (en) 1985-07-31

Family

ID=6215587

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA849319A ZA849319B (en) 1983-11-30 1984-11-29 New cephalosporins and process for their preparation

Country Status (16)

Country Link
US (2) US4757065A (es)
EP (1) EP0144032B1 (es)
JP (1) JPS60136587A (es)
KR (1) KR850003540A (es)
AT (1) ATE36160T1 (es)
AU (1) AU572916B2 (es)
CA (1) CA1275285C (es)
DE (2) DE3343208A1 (es)
DK (1) DK568484A (es)
ES (3) ES8603896A1 (es)
GR (1) GR81082B (es)
HU (1) HU193470B (es)
IL (1) IL73644A (es)
PH (1) PH22176A (es)
PT (1) PT79552B (es)
ZA (1) ZA849319B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3419012A1 (de) * 1984-05-22 1985-11-28 Bayer Ag, 5090 Leverkusen Ss-lactamantibiotika, verfahren zu deren herstellung sowie ihre verwendung als arzneimittel oder wachstumsfoerderer in der tieraufzucht oder als antioxidantien
AU580855B2 (en) * 1985-03-29 1989-02-02 Shionogi & Co., Ltd. Alkeneamidocephalosporin esters
US5171854A (en) * 1987-05-26 1992-12-15 Bayer Aktiengesellschaft Substituted vinylcephalosporins
DE3807232A1 (de) * 1988-03-05 1989-09-14 Bayer Ag Substituierte acrylsaeureester
US5285455A (en) * 1992-02-03 1994-02-08 Lsi Logic Corporation Serial data encoder
US5471485A (en) * 1992-11-24 1995-11-28 Lsi Logic Corporation Reed-solomon decoder using discrete time delay in power sum computation
TWI671317B (zh) 2013-08-02 2019-09-11 輝瑞大藥廠 抗ｃｘｃｒ４抗體及抗體-藥物結合物
CN110294770A (zh) * 2019-08-14 2019-10-01 齐鲁晟华制药有限公司 一种头孢烯类鎓盐化合物、制备方法及以该化合物合成头孢喹肟的方法
CN113801142A (zh) * 2021-10-28 2021-12-17 重庆医药高等专科学校 一种硫酸头孢喹肟中间体7-氨基头孢喹肟的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1497039A (en) * 1973-12-05 1978-01-05 Glaxo Lab Ltd Penicillins and cephalosporins
GB2076801A (en) * 1980-04-14 1981-12-09 Erba Farmitalia alpha , beta -Disubstituted Acrylamido Cephalosporins
DE3037997A1 (de) * 1980-10-08 1982-05-13 Bayer Ag (beta) -lactamantibiotika, verfahren zu deren herstellung sowie sie enthaltende mittel
JPS5818387A (ja) * 1981-07-27 1983-02-02 Sagami Chem Res Center β−ラクタム誘導体
DE3145727A1 (de) * 1981-11-19 1983-05-26 Bayer Ag, 5090 Leverkusen Zwischenprodukte, verfahren zu deren herstellung und verfahren zur herstellung von cephalosporinen
DE3239365A1 (de) * 1982-10-23 1984-04-26 Bayer Ag, 5090 Leverkusen Neue cephalosporine und verfahren zu ihrer herstellung
DE3419012A1 (de) * 1984-05-22 1985-11-28 Bayer Ag, 5090 Leverkusen Ss-lactamantibiotika, verfahren zu deren herstellung sowie ihre verwendung als arzneimittel oder wachstumsfoerderer in der tieraufzucht oder als antioxidantien

Also Published As

Publication number Publication date
CA1275285C (en) 1990-10-16
ES546633A0 (es) 1986-03-01
HUT37623A (en) 1986-01-23
PT79552B (en) 1986-09-15
ES537857A0 (es) 1986-01-01
JPS60136587A (ja) 1985-07-20
PT79552A (en) 1984-12-01
EP0144032A2 (de) 1985-06-12
ATE36160T1 (de) 1988-08-15
DK568484A (da) 1985-05-31
DK568484D0 (da) 1984-11-29
ES8604976A1 (es) 1986-03-01
ES8603896A1 (es) 1986-01-01
DE3473146D1 (en) 1988-09-08
GR81082B (en) 1985-03-27
AU572916B2 (en) 1988-05-19
US4757065A (en) 1988-07-12
DE3343208A1 (de) 1985-06-05
US4767754A (en) 1988-08-30
PH22176A (en) 1988-06-28
EP0144032B1 (de) 1988-08-03
EP0144032A3 (en) 1986-03-19
ES546632A0 (es) 1986-03-01
HU193470B (en) 1987-10-28
AU3567684A (en) 1985-06-06
IL73644A0 (en) 1985-02-28
KR850003540A (ko) 1985-06-20
ES8604977A1 (es) 1986-03-01
IL73644A (en) 1989-02-28

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