ZA751394B - Novel benzomorphanes,possessing analgesic effects - Google Patents

Novel benzomorphanes,possessing analgesic effects

Info

Publication number: ZA751394B
Authority: ZA; South Africa
Prior art keywords: benzomorphanes; novel; analgesic effects; possessing analgesic; possessing
Prior art date: 1974-03-09

Application number

ZA751394A

Other languages

English (en)

Inventor

Herberg Merz

Merz Herberg

Adolf Langbein

Langbein Adolf

Gerhard Walther

Walther Gerhard

Klaus Stockhaus

Stockhaus Klaus

Original Assignee

Boehringer Sohn Ingelheim

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-03-09

Filing date

1975-03-07

Publication date

1976-11-24

1975-03-07 Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim

1976-11-24 Publication of ZA751394B publication Critical patent/ZA751394B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Neurosurgery (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pain & Pain Management (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

ZA751394A 1974-03-09 1975-03-07 Novel benzomorphanes,possessing analgesic effects ZA751394B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE2411382A DE2411382C3 (de)	1974-03-09	1974-03-09	2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung

Publications (1)

Publication Number	Publication Date
ZA751394B true ZA751394B (en)	1976-11-24

Family

ID=5909593

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA751394A ZA751394B (en)	1974-03-09	1975-03-07	Novel benzomorphanes,possessing analgesic effects

Country Status (25)

Country	Link
JP (1)	JPS5827275B2 (da)
AT (1)	AT344332B (da)
BE (1)	BE826440A (da)
BG (3)	BG24814A4 (da)
CA (1)	CA1049511A (da)
CH (8)	CH612425A5 (da)
CS (1)	CS188221B2 (da)
DD (1)	DD119236A5 (da)
DE (1)	DE2411382C3 (da)
DK (1)	DK137188C (da)
ES (6)	ES440347A1 (da)
FI (1)	FI63571C (da)
FR (1)	FR2262984B1 (da)
GB (1)	GB1496418A (da)
HU (1)	HU177408B (da)
IE (1)	IE40945B1 (da)
IL (1)	IL46760A (da)
NL (1)	NL7502724A (da)
NO (1)	NO141800C (da)
PH (1)	PH14127A (da)
PL (3)	PL93700B1 (da)
RO (2)	RO70051A (da)
SE (1)	SE421919B (da)
SU (3)	SU577982A3 (da)
ZA (1)	ZA751394B (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2716687A1 (de) *	1977-04-15	1978-10-19	Boehringer Sohn Ingelheim	2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
DE2828039A1 (de) *	1978-06-26	1980-01-10	Boehringer Sohn Ingelheim	2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
JP3955093B2 (ja) *	1995-03-10	2007-08-08	フォトキュアエイエスエイ	光化学治療における光増感剤としての５−アミノレブリン酸のエステル
US6492420B2 (en)	1995-03-10	2002-12-10	Photocure As	Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6992107B1 (en)	1995-03-10	2006-01-31	Photocure Asa	Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
US7530461B2 (en)	1995-03-10	2009-05-12	Photocure Asa	Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
GB0018528D0 (en)	2000-07-27	2000-09-13	Photocure Asa	Compounds
US6723750B2 (en)	2002-03-15	2004-04-20	Allergan, Inc.	Photodynamic therapy for pre-melanomas
EP2183228B1 (en)	2007-07-26	2014-08-20	Vitae Pharmaceuticals, Inc.	CYCLIC INHIBITORS OF 11ß -HYDROXYSTERIOD DEHYDROGENASE 1
US8859580B2 (en)	2007-11-16	2014-10-14	Boehringer Ingelheim International Gmbh	Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
CA2708303A1 (en)	2007-12-11	2009-06-18	Vitae Pharmaceuticals, Inc.	Cyclic urea inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1
TW200934490A (en)	2008-01-07	2009-08-16	Vitae Pharmaceuticals Inc	Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
WO2009094169A1 (en)	2008-01-24	2009-07-30	Vitae Pharmaceuticals, Inc.	Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CA2715290A1 (en)	2008-02-15	2009-08-20	Vitae Pharmaceuticals, Inc.	Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
TW200946520A (en)	2008-05-01	2009-11-16	Vitae Pharmaceuticals Inc	Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2291370B1 (en)	2008-05-01	2013-11-27	Vitae Pharmaceuticals, Inc.	Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CA2723039A1 (en)	2008-05-01	2009-11-05	Vitae Pharmaceuticals, Inc.	Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2288596B1 (en)	2008-05-13	2016-11-30	Boehringer Ingelheim International GmbH	Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
WO2010010157A2 (en)	2008-07-25	2010-01-28	Boehringer Ingelheim International Gmbh	INHIBITORS OF 11beta-HYDROXYSTEROID DEHYDROGENASE 1
KR20110050459A (ko)	2008-07-25	2011-05-13	비타이 파마슈티컬즈, 인코포레이티드	11베타-하이드록시스테로이드 탈수소효소 1의 고리형 억제제
MA33216B1 (fr)	2009-04-30	2012-04-02	Boehringer Ingelheim Int	Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
JP5656986B2 (ja)	2009-06-11	2015-01-21	ヴァイティーファーマシューティカルズ，インコーポレイテッド	１，３−オキサジナン−２−オン構造に基づく１１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状阻害剤
AR078887A1 (es)	2009-11-06	2011-12-07	Boehringer Ingelheim Int	Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina y composiciones farmaceuticas que los contienen.
US8933072B2 (en)	2010-06-16	2015-01-13	Vitae Pharmaceuticals, Inc.	Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (zh)	2010-11-05	2016-06-11	百靈佳殷格翰國際股份有限公司	六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
EP2744783A1 (en)	2011-08-17	2014-06-25	Boehringer Ingelheim International GmbH	Indenopyridine derivatives

1974
- 1974-03-09 DE DE2411382A patent/DE2411382C3/de not_active Expired
1975
- 1975-02-28 AT AT153875A patent/AT344332B/de not_active IP Right Cessation
- 1975-03-05 SU SU7502110984A patent/SU577982A3/ru active
- 1975-03-05 CH CH280275A patent/CH612425A5/xx not_active IP Right Cessation
- 1975-03-06 FI FI750652A patent/FI63571C/fi not_active IP Right Cessation
- 1975-03-07 SE SE7502592A patent/SE421919B/xx not_active IP Right Cessation
- 1975-03-07 RO RO7589654A patent/RO70051A/ro unknown
- 1975-03-07 BE BE154138A patent/BE826440A/xx not_active IP Right Cessation
- 1975-03-07 BG BG030538A patent/BG24814A4/xx unknown
- 1975-03-07 DD DD184642A patent/DD119236A5/xx unknown
- 1975-03-07 CA CA221,554A patent/CA1049511A/en not_active Expired
- 1975-03-07 DK DK92975A patent/DK137188C/da active
- 1975-03-07 RO RO7589653A patent/RO69617A/ro unknown
- 1975-03-07 NO NO750773A patent/NO141800C/no unknown
- 1975-03-07 BG BG029183A patent/BG25087A3/xx unknown
- 1975-03-07 ZA ZA751394A patent/ZA751394B/xx unknown
- 1975-03-07 BG BG030537A patent/BG24813A4/xx unknown
- 1975-03-07 NL NL7502724A patent/NL7502724A/xx not_active Application Discontinuation
- 1975-03-07 GB GB9633/75A patent/GB1496418A/en not_active Expired
- 1975-03-07 IE IE505/75A patent/IE40945B1/xx unknown
- 1975-03-07 FR FR7507239A patent/FR2262984B1/fr not_active Expired
- 1975-03-07 HU HU75BO1536A patent/HU177408B/hu unknown
- 1975-03-07 IL IL46760A patent/IL46760A/xx unknown
- 1975-03-07 JP JP50027915A patent/JPS5827275B2/ja not_active Expired
- 1975-03-08 PL PL1975191319A patent/PL93700B1/pl unknown
- 1975-03-08 PL PL1975178582A patent/PL93499B1/pl unknown
- 1975-03-08 PL PL1975191318A patent/PL93699B1/pl unknown
- 1975-03-10 PH PH16895A patent/PH14127A/en unknown
- 1975-03-10 CS CS751583A patent/CS188221B2/cs unknown
- 1975-08-20 ES ES440347A patent/ES440347A1/es not_active Expired
- 1975-08-20 ES ES440350A patent/ES440350A1/es not_active Expired
- 1975-08-20 ES ES440345A patent/ES440345A1/es not_active Expired
- 1975-08-20 ES ES440349A patent/ES440349A1/es not_active Expired
- 1975-08-20 ES ES440348A patent/ES440348A1/es not_active Expired
- 1975-08-20 ES ES440346A patent/ES440346A1/es not_active Expired
- 1975-12-19 SU SU7502199294A patent/SU577983A3/ru active
- 1975-12-19 SU SU752199295A patent/SU588916A3/ru active
1979
- 1979-04-24 CH CH384379A patent/CH620439A5/de not_active IP Right Cessation
- 1979-04-24 CH CH384879A patent/CH620681A5/de not_active IP Right Cessation
- 1979-04-24 CH CH384979A patent/CH622017A5/de not_active IP Right Cessation
- 1979-04-24 CH CH384679A patent/CH620440A5/de not_active IP Right Cessation
- 1979-04-24 CH CH384579A patent/CH622015A5/de not_active IP Right Cessation
- 1979-04-24 CH CH384479A patent/CH622014A5/de not_active IP Right Cessation
- 1979-04-24 CH CH384779A patent/CH622016A5/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
CS188221B2 (en)	1979-02-28
CH622016A5 (en)	1981-03-13
NL7502724A (nl)	1975-09-11
IL46760A (en)	1978-12-17
ES440345A1 (es)	1977-03-01
CH622014A5 (en)	1981-03-13
FI63571B (fi)	1983-03-31
IE40945L (en)	1975-09-09
SU577983A3 (ru)	1977-10-25
ES440350A1 (es)	1977-03-16
NO141800C (no)	1980-06-04
BG24814A4 (en)	1978-05-12
FR2262984A1 (da)	1975-10-03
AU7894275A (en)	1976-09-16
BE826440A (fr)	1975-09-08
ES440348A1 (es)	1977-06-01
DE2411382A1 (de)	1975-09-18
CA1049511A (en)	1979-02-27
ES440347A1 (es)	1977-06-01
ES440346A1 (es)	1977-03-01
CH612425A5 (en)	1979-07-31
IL46760A0 (en)	1975-05-22
FR2262984B1 (da)	1978-07-28
DK137188B (da)	1978-01-30
FI63571C (fi)	1983-07-11
ES440349A1 (es)	1977-03-01
IE40945B1 (en)	1979-09-12
SU588916A3 (ru)	1978-01-15
CH620439A5 (en)	1980-11-28
ATA153875A (de)	1977-11-15
AT344332B (de)	1978-07-10
NO141800B (no)	1980-02-04
CH620440A5 (en)	1980-11-28
BG24813A4 (en)	1978-05-12
HU177408B (en)	1981-10-28
RO69617A (ro)	1980-08-15
DK92975A (da)	1975-09-10
DE2411382B2 (de)	1979-01-18
PL93699B1 (da)	1977-06-30
RO70051A (ro)	1980-12-30
DD119236A5 (da)	1976-04-12
SE421919B (sv)	1982-02-08
JPS5827275B2 (ja)	1983-06-08
DK137188C (da)	1978-07-03
JPS50123675A (da)	1975-09-29
CH622017A5 (en)	1981-03-13
CH622015A5 (en)	1981-03-13
BG25087A3 (en)	1978-07-12
NO750773L (da)	1975-09-10
FI750652A (da)	1975-09-10
DE2411382C3 (de)	1979-09-06
PL93700B1 (da)	1977-06-30
SE7502592L (da)	1975-09-10
CH620681A5 (en)	1980-12-15
SU577982A3 (ru)	1977-10-25
PL93499B1 (da)	1977-05-30
PH14127A (en)	1981-02-26
GB1496418A (en)	1977-12-30

Publication	Publication Date	Title
ZA751394B (en)	1976-11-24	Novel benzomorphanes,possessing analgesic effects
JPS5113709A (en)	1976-02-03	Echiren no ensokajudotai no seizoho
JPS5183738A (en)	1976-07-22	Moji no atsushukujohochozohoho
GB1517973A (en)	1978-07-19	6-methyl-8alpha-n,n-dimethylsulphamoylaminoergoline i
ZA754630B (en)	1976-07-28	2-thiol-4,5-diphenyloxazole s-derivatives
CA1029374A (en)	1978-04-11	2-substituted-5,6-dimethoxyindazoles
JPS5119744A (en)	1976-02-17	Koseibutsushitsu xkk6222 no shinkyudotainoseiho
JPS5183225A (en)	1976-07-21	Ben mataha soretodoshunomononotameno ichihyojiki
JPS511668A (en)	1976-01-08	Komekojojinzomai no seizoho
JPS511666A (en)	1976-01-08	Kakokokuruifunmatsu no seizoho
JPS5113474A (en)	1976-02-02	Kendakueki no zoryubunrisochi
GB1516534A (en)	1978-07-05	Basically substituted 3,4-dihydro-2h-isoquinolin-1-thione
JPS511661A (en)	1976-01-08	Kaatsukyoseitairyu nyoru kokurui no tankijoshahoho
IL47487A0 (en)	1975-08-31	9-thia-or oxothia-and dioxothia-11,12-seco-prostaglandins
JPS511554A (en)	1976-01-08	Senjohoriesuteru no seizoho
JPS5131788A (en)	1976-03-18	Kitosan no shorihoho
JPS511664A (en)	1976-01-08	Patsukuiryudemen no seizoho
JPS5115105A (en)	1976-02-06	Judoki no kyusokukatsuteisonshitsunasuitsuchinguyokairo
JPS5118187A (en)	1976-02-13	Kenzobutsuyori no hinansochi
JPS5120271A (en)	1976-02-18	Taidenboshipaipu no seikeihoho
PH13535A (en)	1980-06-19	Cyclohexa-2,5-diene-1-thiones
JPS514277A (en)	1976-01-14	As jushifunmatsuofukumu ekinoshoriho
JPS511663A (en)	1976-01-08	Chukamen no seizoho
JPS5138982A (en)	1976-03-31	Handotaiseiryusochi no seizohoho
JPS5135091A (en)	1976-03-25	Densohinhe no ketsusenkozo