ZA200902587B - Water insoluble polymer matrix for drug delivery - Google Patents
Water insoluble polymer matrix for drug deliveryInfo
- Publication number
- ZA200902587B ZA200902587B ZA200902587A ZA200902587A ZA200902587B ZA 200902587 B ZA200902587 B ZA 200902587B ZA 200902587 A ZA200902587 A ZA 200902587A ZA 200902587 A ZA200902587 A ZA 200902587A ZA 200902587 B ZA200902587 B ZA 200902587B
- Authority
- ZA
- South Africa
- Prior art keywords
- drug delivery
- polymer matrix
- water insoluble
- insoluble polymer
- water
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US85800406P | 2006-11-09 | 2006-11-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200902587B true ZA200902587B (en) | 2010-06-30 |
Family
ID=39468600
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200902587A ZA200902587B (en) | 2006-11-09 | 2007-11-08 | Water insoluble polymer matrix for drug delivery |
Country Status (15)
Country | Link |
---|---|
US (1) | US8632809B2 (ja) |
EP (2) | EP2091514B1 (ja) |
JP (2) | JP5411703B2 (ja) |
KR (2) | KR20090082447A (ja) |
CN (1) | CN101553206B (ja) |
AR (1) | AR063621A1 (ja) |
AU (1) | AU2007325409B2 (ja) |
BR (1) | BRPI0718696A2 (ja) |
CA (1) | CA2668814A1 (ja) |
ES (2) | ES2477993T3 (ja) |
MX (1) | MX2009004856A (ja) |
PL (1) | PL2091514T3 (ja) |
TW (1) | TWI409081B (ja) |
WO (1) | WO2008067127A2 (ja) |
ZA (1) | ZA200902587B (ja) |
Families Citing this family (50)
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US20080114076A1 (en) * | 2006-11-09 | 2008-05-15 | Alcon Manufacturing Ltd. | Punctal plug comprising a water-insoluble polymeric matrix |
US20110123481A1 (en) * | 2007-08-16 | 2011-05-26 | Remedor Biomed Ltd. | Erythropoietin and fibronectin compositions for therapeutic and cosmetic applications |
US20100226962A1 (en) * | 2009-03-03 | 2010-09-09 | Rodstrom Theron R | Peri-corneal drug delivery device |
US8889193B2 (en) | 2010-02-25 | 2014-11-18 | The Johns Hopkins University | Sustained delivery of therapeutic agents to an eye compartment |
US8211450B2 (en) * | 2010-05-05 | 2012-07-03 | Senju Usa, Inc. | Ophthalmic composition |
US10307372B2 (en) | 2010-09-10 | 2019-06-04 | The Johns Hopkins University | Rapid diffusion of large polymeric nanoparticles in the mammalian brain |
CN103619327A (zh) * | 2010-12-29 | 2014-03-05 | 嘉德治疗股份有限公司 | 眼部给药体系 |
WO2012109363A2 (en) | 2011-02-08 | 2012-08-16 | The Johns Hopkins University | Mucus penetrating gene carriers |
US9415020B2 (en) | 2012-01-19 | 2016-08-16 | The Johns Hopkins University | Nanoparticle formulations with enhanced mucosal penetration |
JP5883539B2 (ja) | 2012-03-16 | 2016-03-15 | ザ・ジョンズ・ホプキンス・ユニバーシティー | Hif−1阻害剤の送達のための放出制御製剤 |
US10159743B2 (en) | 2012-03-16 | 2018-12-25 | The Johns Hopkins University | Non-linear multiblock copolymer-drug conjugates for the delivery of active agents |
US20150133434A1 (en) * | 2012-03-28 | 2015-05-14 | The J. David Gladstone Institutes | Compositions and Methods for Reactivating Latent Immunodeficiency Virus |
US20140107025A1 (en) * | 2012-04-16 | 2014-04-17 | Jade Therapeutics, Llc | Ocular drug delivery system |
WO2013166385A1 (en) | 2012-05-03 | 2013-11-07 | Kala Pharmaceuticals, Inc. | Pharmaceutical nanoparticles showing improved mucosal transport |
US11596599B2 (en) | 2012-05-03 | 2023-03-07 | The Johns Hopkins University | Compositions and methods for ophthalmic and/or other applications |
JP6360040B2 (ja) | 2012-05-03 | 2018-07-18 | カラ ファーマシューティカルズ インコーポレイテッド | 粘液浸透性被覆粒子、組成物、医薬組成物、医薬製剤、及びそれらの形成方法 |
US9827191B2 (en) | 2012-05-03 | 2017-11-28 | The Johns Hopkins University | Compositions and methods for ophthalmic and/or other applications |
US9889208B2 (en) | 2012-05-04 | 2018-02-13 | The Johns Hopkins University | Lipid-based drug carriers for rapid penetration through mucus linings |
WO2014124006A1 (en) | 2013-02-05 | 2014-08-14 | The Johns Hopkins University | Nanoparticles for magnetic resonance imaging tracking and methods of making and using thereof |
WO2015046281A1 (ja) * | 2013-09-26 | 2015-04-02 | 参天製薬株式会社 | 安定化された2-アミノ-3-(4-ブロモベンゾイル)フェニル酢酸含有水性組成物 |
US20160199495A1 (en) | 2014-01-13 | 2016-07-14 | Alexander G. Gorkovenko | Polymer Compositions in Biomedical Applications |
WO2015127389A1 (en) | 2014-02-23 | 2015-08-27 | The Johns Hopkins University | Hypotonic enema formulations and methods of use |
JP6678656B2 (ja) * | 2014-09-19 | 2020-04-08 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited | 新規な可溶性グアニル酸シクラーゼ活性剤およびそれらの使用 |
EP3233058A1 (en) | 2014-12-15 | 2017-10-25 | The Johns Hopkins University | Sunitinib formulations and methods for use thereof in treatment of glaucoma |
KR20170106460A (ko) | 2015-01-27 | 2017-09-20 | 더 존스 홉킨스 유니버시티 | 점막표면에서 활성제의 향상된 수송을 위한 저장성 하이드로겔 제제 |
EP3340982B1 (en) | 2015-08-26 | 2021-12-15 | Achillion Pharmaceuticals, Inc. | Compounds for treatment of immune and inflammatory disorders |
AR106018A1 (es) | 2015-08-26 | 2017-12-06 | Achillion Pharmaceuticals Inc | Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos |
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US10835578B2 (en) | 2016-01-08 | 2020-11-17 | Ascendis Pharma Growth Disorders A/S | CNP prodrugs with large carrier moieties |
CA3007987C (en) | 2016-01-08 | 2023-08-29 | Ascendis Pharma Growth Disorders A/S | Controlled-release cnp agonists with low npr-c binding |
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US10603274B2 (en) * | 2016-09-30 | 2020-03-31 | Mati Therapeutics Inc. | Ophthalmic drug sustained release formulation and uses thereof |
EP3518897B1 (en) * | 2016-09-30 | 2022-02-09 | Mati Therapeutics Inc. | Ophthalmic drug sustained release formulation and uses thereof |
IL294069B2 (en) | 2017-03-01 | 2023-11-01 | Achillion Pharmaceuticals Inc | Aryl, heteroaryl and heterocyclic pharmaceutical compounds for the treatment of medical disorders |
BR112019017103A2 (pt) | 2017-03-10 | 2020-04-14 | Quiapeg Pharmaceuticals Ab | conjugados liberáveis |
EP3600324A4 (en) | 2017-03-23 | 2020-12-09 | Graybug Vision, Inc. | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF EYE DISORDERS |
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KR20210100005A (ko) * | 2018-03-29 | 2021-08-13 | 마티 테라퓨틱스 인코포레이티드 | 안과 약제의 서방성 제형 및 건성 증후군 치료 용도 |
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EP3846803A4 (en) | 2018-09-06 | 2022-08-10 | Achillion Pharmaceuticals, Inc. | Macrocyclic compounds for the treatment of medical disorders |
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-
2007
- 2007-11-08 MX MX2009004856A patent/MX2009004856A/es active IP Right Grant
- 2007-11-08 BR BRPI0718696-7A patent/BRPI0718696A2/pt not_active IP Right Cessation
- 2007-11-08 CN CN2007800415722A patent/CN101553206B/zh not_active Expired - Fee Related
- 2007-11-08 AU AU2007325409A patent/AU2007325409B2/en not_active Ceased
- 2007-11-08 AR ARP070104980A patent/AR063621A1/es not_active Application Discontinuation
- 2007-11-08 ES ES11186042.5T patent/ES2477993T3/es active Active
- 2007-11-08 ZA ZA200902587A patent/ZA200902587B/xx unknown
- 2007-11-08 TW TW096142200A patent/TWI409081B/zh not_active IP Right Cessation
- 2007-11-08 EP EP07871406.0A patent/EP2091514B1/en not_active Not-in-force
- 2007-11-08 JP JP2009536472A patent/JP5411703B2/ja not_active Expired - Fee Related
- 2007-11-08 KR KR1020097011149A patent/KR20090082447A/ko not_active Abandoned
- 2007-11-08 US US11/936,914 patent/US8632809B2/en not_active Expired - Fee Related
- 2007-11-08 KR KR1020147004349A patent/KR20140032505A/ko not_active Ceased
- 2007-11-08 EP EP11186042.5A patent/EP2409687B1/en not_active Not-in-force
- 2007-11-08 PL PL07871406T patent/PL2091514T3/pl unknown
- 2007-11-08 ES ES07871406T patent/ES2421206T3/es active Active
- 2007-11-08 WO PCT/US2007/084023 patent/WO2008067127A2/en active Application Filing
- 2007-11-08 CA CA002668814A patent/CA2668814A1/en not_active Abandoned
-
2013
- 2013-04-03 JP JP2013077416A patent/JP2013129679A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
AR063621A1 (es) | 2009-02-04 |
AU2007325409A1 (en) | 2008-06-05 |
CN101553206B (zh) | 2012-11-21 |
WO2008067127A2 (en) | 2008-06-05 |
EP2409687B1 (en) | 2014-06-11 |
US8632809B2 (en) | 2014-01-21 |
MX2009004856A (es) | 2009-06-05 |
ES2421206T3 (es) | 2013-08-29 |
TW200826963A (en) | 2008-07-01 |
JP2013129679A (ja) | 2013-07-04 |
CA2668814A1 (en) | 2008-06-05 |
JP2010509361A (ja) | 2010-03-25 |
EP2091514B1 (en) | 2013-06-05 |
TWI409081B (zh) | 2013-09-21 |
US20080113027A1 (en) | 2008-05-15 |
JP5411703B2 (ja) | 2014-02-12 |
CN101553206A (zh) | 2009-10-07 |
KR20090082447A (ko) | 2009-07-30 |
BRPI0718696A2 (pt) | 2013-12-31 |
ES2477993T3 (es) | 2014-07-18 |
PL2091514T3 (pl) | 2014-03-31 |
AU2007325409B2 (en) | 2013-03-28 |
WO2008067127A3 (en) | 2008-10-09 |
KR20140032505A (ko) | 2014-03-14 |
HK1132173A1 (en) | 2010-02-19 |
EP2409687A1 (en) | 2012-01-25 |
EP2091514A2 (en) | 2009-08-26 |
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