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YU62689A - N-acyl derivatives of peptidoglican monomer, their pharmaceutically acceptable salts, process for preparing thereof and their use as immunity modulators and immunoadjuvant - Google Patents

N-acyl derivatives of peptidoglican monomer, their pharmaceutically acceptable salts, process for preparing thereof and their use as immunity modulators and immunoadjuvant

Info

Publication number
YU62689A
YU62689A YU00626/89A YU62689A YU62689A YU 62689 A YU62689 A YU 62689A YU 00626/89 A YU00626/89 A YU 00626/89A YU 62689 A YU62689 A YU 62689A YU 62689 A YU62689 A YU 62689A
Authority
YU
Yugoslavia
Prior art keywords
peptidoglican
immunoadjuvant
monomer
preparing
pharmaceutically acceptable
Prior art date
Application number
YU00626/89A
Other languages
English (en)
Inventor
B Suskovic
R Naumski
Z Mubrin
V Gomercic
Original Assignee
Pliva Pharm & Chem Works
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva Pharm & Chem Works filed Critical Pliva Pharm & Chem Works
Priority to YU00626/89A priority Critical patent/YU62689A/xx
Priority to CA002013065A priority patent/CA2013065A1/en
Priority to SU904743571A priority patent/RU1779258C/ru
Priority to EP19900105723 priority patent/EP0390039A3/en
Priority to DD90339076A priority patent/DD296085A5/de
Priority to HU901831A priority patent/HU202546B/hu
Priority to US07/499,586 priority patent/US5153173A/en
Priority to JP2075786A priority patent/JPH04193898A/ja
Priority to PL28448190A priority patent/PL162969B1/pl
Priority to RO144579A priority patent/RO105699B1/ro
Priority to CS901490A priority patent/CS149090A2/cs
Priority to BG91592A priority patent/BG51456A3/xx
Publication of YU62689A publication Critical patent/YU62689A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
YU00626/89A 1989-03-27 1989-03-27 N-acyl derivatives of peptidoglican monomer, their pharmaceutically acceptable salts, process for preparing thereof and their use as immunity modulators and immunoadjuvant YU62689A (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
YU00626/89A YU62689A (en) 1989-03-27 1989-03-27 N-acyl derivatives of peptidoglican monomer, their pharmaceutically acceptable salts, process for preparing thereof and their use as immunity modulators and immunoadjuvant
CA002013065A CA2013065A1 (en) 1989-03-27 1990-03-26 N-acyl derivatives of the peptidoglycan monomer, pharmaceutically acceptable salts thereof, their preparation and use in the manufacture of immunomodulators and immunoadjuvants
SU904743571A RU1779258C (ru) 1989-03-27 1990-03-26 Способ получени N-ацильных производных пептидогликанового мономера или их фармацевтических солей
EP19900105723 EP0390039A3 (en) 1989-03-27 1990-03-26 N-acyl derivatives of the peptidoglycan monomer, pharmaceutically acceptable salts thereof, their preparation and use in the manufacture of immunomodulators and immunoadjuvants
DD90339076A DD296085A5 (de) 1989-03-27 1990-03-26 N-acylderivate des peptideglyenmonoomers, verfahren zur herstellung und ihre verwendung
HU901831A HU202546B (en) 1989-03-27 1990-03-26 Process for producing peptiodglycan monomer n-acyl derivatives and pharmaceutical compositions comprising same as active ingredient
US07/499,586 US5153173A (en) 1989-03-27 1990-03-27 N-acyl derivatives of the peptidoglycan monomer, pharmaceutically acceptable salts thereof, their preparation and use as immunomodulators and immunoadjuvants
JP2075786A JPH04193898A (ja) 1989-03-27 1990-03-27 ペプチドガリカンモノマーのｎ‐アシル誘導体、その製薬上許容しうる塩、それらの製造法及び免疫調整剤としての使用
PL28448190A PL162969B1 (en) 1989-03-27 1990-03-27 Method of obtaining n-acyl derivatives of monomeric peptideglicane
RO144579A RO105699B1 (ro) 1989-03-27 1990-03-27 N-acil-derivati ai peptidglicanului monomer si procedeu pentru prepararea acestora
CS901490A CS149090A2 (en) 1989-03-27 1990-03-27 Method of peptidoglycan's monomer's n-acyl derivatives preparation
BG91592A BG51456A3 (en) 1989-03-27 1990-03-27 Process for the preparation of n-acyl derivatives of the peptideglucan monomer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
YU00626/89A YU62689A (en) 1989-03-27 1989-03-27 N-acyl derivatives of peptidoglican monomer, their pharmaceutically acceptable salts, process for preparing thereof and their use as immunity modulators and immunoadjuvant

Publications (1)

Publication Number Publication Date
YU62689A true YU62689A (en) 1991-02-28

Family

ID=25550749

Family Applications (1)

Application Number Title Priority Date Filing Date
YU00626/89A YU62689A (en) 1989-03-27 1989-03-27 N-acyl derivatives of peptidoglican monomer, their pharmaceutically acceptable salts, process for preparing thereof and their use as immunity modulators and immunoadjuvant

Country Status (12)

Country Link
US (1) US5153173A (hu)
EP (1) EP0390039A3 (hu)
JP (1) JPH04193898A (hu)
BG (1) BG51456A3 (hu)
CA (1) CA2013065A1 (hu)
CS (1) CS149090A2 (hu)
DD (1) DD296085A5 (hu)
HU (1) HU202546B (hu)
PL (1) PL162969B1 (hu)
RO (1) RO105699B1 (hu)
RU (1) RU1779258C (hu)
YU (1) YU62689A (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE125270T1 (de) * 1990-12-21 1995-08-15 Pliva Pharm & Chem Works Tert-butyloxycarbonyl-l-tyrosyl- peptidoglycanmonomer und deren 125 i-markiertes derivat, deren herstellung und verwendung.
CA2115270A1 (en) * 1991-08-15 1993-03-04 Biserka Radosevic-Stasic The use of the peptidoglycan monomer (pgm), its n-acyl derivatives, and its metal complexes in the preparation of medicaments for the correction of the immunosuppressive and hepatosuppressive states of the organism
AU2574199A (en) 1998-02-02 1999-08-16 Princeton University Substrate analogs for murg, methods of making same and assays using same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU40472B (en) * 1977-03-22 1986-02-28 Pliva Pharm & Chem Works Process for obtaining the basic repeated disaccharide-pentapeptide unit of peptidoglycane from the peptidoglycane complex generated in the submersion culturing of microorganisms
JPS58198496A (ja) * 1982-05-14 1983-11-18 Dainippon Pharmaceut Co Ltd グルコサミニルムラミルペプチド誘導体
YU45382B (en) * 1986-11-19 1992-05-28 Pliva Sour Zagreb Process for preparing complex of n-acethyl-glucosis-aminyl-n-acethyl-muramoil-l-alanyl-d-izoglutaminyl-(l)-mezodiaminopimelyl-(d-amid)-(l)-al

Also Published As

Publication number Publication date
CS149090A2 (en) 1991-08-13
EP0390039A3 (en) 1991-11-13
PL162969B1 (en) 1994-01-31
CA2013065A1 (en) 1990-09-27
BG51456A3 (en) 1993-05-14
HU901831D0 (en) 1990-08-28
RU1779258C (ru) 1992-11-30
RO105699B1 (ro) 1992-11-30
EP0390039A2 (en) 1990-10-03
JPH04193898A (ja) 1992-07-13
HU202546B (en) 1991-03-28
DD296085A5 (de) 1991-11-21
US5153173A (en) 1992-10-06
HUT53661A (en) 1990-11-28

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