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WO2005029956A1 - 均一拡散性粒状農薬製剤 - Google Patents

均一拡散性粒状農薬製剤 Download PDF

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Publication number
WO2005029956A1
WO2005029956A1 PCT/JP2004/013776 JP2004013776W WO2005029956A1 WO 2005029956 A1 WO2005029956 A1 WO 2005029956A1 JP 2004013776 W JP2004013776 W JP 2004013776W WO 2005029956 A1 WO2005029956 A1 WO 2005029956A1
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WO
WIPO (PCT)
Prior art keywords
pesticide
parts
water
active ingredient
granular pesticide
Prior art date
Application number
PCT/JP2004/013776
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English (en)
French (fr)
Japanese (ja)
Inventor
Kiyotoshi Nishiyama
Toshio Sugimura
Tetsuo Ohkawa
Original Assignee
Kumiai Chemical Industry Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kumiai Chemical Industry Co., Ltd. filed Critical Kumiai Chemical Industry Co., Ltd.
Priority to CN2004800275333A priority Critical patent/CN1856247B/zh
Priority to KR1020067001630A priority patent/KR101130428B1/ko
Priority to JP2005514188A priority patent/JP4919662B2/ja
Publication of WO2005029956A1 publication Critical patent/WO2005029956A1/ja

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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/12—Powders or granules
    • A01N25/14—Powders or granules wettable
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/12—Powders or granules
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines

Definitions

  • the present invention relates to a homogeneously diffusible granular pesticide formulation that can exert its medicinal properties for a long period of time, reduce or prevent phytotoxicity, and reduce the environmental burden.
  • the present invention overcomes the problems associated with conventional granular pesticide preparations, can be prepared by a simple method, and exerts the medicinal properties of the pesticidal active ingredient for a long period of time.
  • the present inventors have conducted intensive studies on a homogeneously diffusible granular pesticide formulation, and as a result, It contains non-disintegrable granular pesticides in which an acidic pesticide active ingredient is blended with a cationic surfactant and a basic substance. Particles with a particle size of 3 mm or more have a particle size distribution of 80% by mass or more and have the property of floating on the water surface. The present inventors have found that the above-mentioned problem can be solved by making it possible to disintegrate on the water surface within 30 minutes, and have accomplished the present invention based on this finding.
  • (1) Contains acidic pesticide active ingredient, cationic surfactant and basic substance Within 30 minutes, contains non-disintegrable pesticide granules that do not disintegrate in water, surfactants and floating ingredients, particle size 3 mm These particles have a particle size distribution of 80% by mass or more and have the property of floating on the water surface immediately after being dropped on the water surface, but have a uniform diffusive particle characteristic of being disintegrated on the water surface within 30 minutes.
  • Pesticide formulation
  • the herbicide is a sulfonylprea compound, the uniform diffusible granular pesticide formulation according to (3),
  • R 1 is a hydrogen atom, an alkyl group or an alkoxyalkyl group
  • a homogeneously diffusible granular pesticide preparation according to the above (3) which is a difluoromethanesulfo-l-lide derivative or a salt thereof represented by the formula:
  • (9) Contains acidic pesticide active ingredient, cationic surfactant and basic substance and does not disintegrate in water within 30 minutes.
  • ⁇ Granulate non-disintegrable pesticide granules together with surfactant and floating ingredient.
  • a method for producing a homogeneously diffusible granular pesticide formulation characterized in that the shape is a spherical shape having a particle diameter of 11 to 20 mm or a horizontally long shape having a minor axis of 1 to 20 mm and a major axis of 3 to 40 mm.
  • Non-disintegrable pesticide granules that contain acidic pesticide active ingredients, cationic surfactants and basic substances that do not disintegrate in water within 30 minutes, and pesticide active ingredients together with surfactants and floating ingredients
  • a method for producing a homogeneously diffusible granular pesticide preparation which is subjected to granulation treatment and has a spherical shape with a particle diameter of 11 to 20 mm, and a horizontal shape of a short diameter of 11 to 20 mm and a long diameter of 3 to 40 mm, and
  • FIG. 1 is an explanatory diagram of a paddy field to which a pesticide formulation is applied in Test Example 2.
  • the non-disintegratable pesticide granules to be contained in the granular pesticide preparation of the present invention do not disintegrate in water within 30 minutes, and retain the original granular form.
  • the acidic pesticidal active ingredient used in the non-disintegrable pesticide granules is not particularly limited, but is usually a herbicide, a plant growth regulator, a bactericide, an insecticide and the like. A range is preferred, and geometric isomers, optical isomers and the like are also included.
  • the herbicide is not particularly limited, but pKa2-7 is particularly preferred, especially sulfol.
  • Urea compounds and the following general formula (I) are particularly limited, but pKa2-7 is particularly preferred, especially sulfol.
  • R 1 is a hydrogen atom, an alkyl group or an alkoxyalkyl group
  • a difluoromethanesulfo-fluoride derivative or a salt thereof is particularly preferred.
  • Examples of the difluoromethanesulfo-l-lide derivative or a salt thereof include compounds described in JP-A-2000-44546, for example, 2-[(4,6-dimethoxypyrimidine-2). -Yl) hydroxymethyl] -N-difluoromethanesulfo-luarylide, 2-[(4,6-dimethoxypyrimidine-2-yl) hydroxymethyl] -6-methoxymethyl-N-difluoromethanesulfo And 2-[(4,6-dimethoxypyrimidin-2-yl) hydroxymethyl] -6-ethyl-N-difluoromethanesulfo-l-lide.
  • the plant growth regulator is not particularly limited, but may be 4'-cloth-2 '-(hi-hydroxybenzyl) isonicotinylide (inavenfide), (2RS, 3RS) -1- (4 -Black mouth ferrule)-
  • insecticide is not particularly limited, O, 0-dimethyl-0- (3-methyl-4-nitrophenyl) thiophosphate (MEP), (2-isopropyl-4-methylpyrimidyl-6) -getyl thiophosphate ( Diazinon), 1-naphthyl-N-methylcarbamate (NAC), O, O-getyl-0- (3-oxo-2-phenyl-2H-pyridazine-6-yl) phosphorothioate (pyridafentione) ), O, O-dimethyl-O-3,5,6-trichloro-2-pyridyl phosphorothioate (chloropyrifosmethyl), dimethyldicarbethoxyxethyl thiophosphate (marathon), O, 0-dimethyl -S- (N-methylcarbamoylmethyl) dithiophosphate (dimethoate), O, 0-dipropyl-0-4-methylthiophen
  • the pKa of the ingredient can be determined, for example, by referring to Experimental Chemistry Lecture 5 (thermal measurement and equilibrium), p469-p474, published on January 20, 1958, Maruzen Co., Ltd. It is measured by the method described.
  • the cationic surfactant used in the present invention is not particularly limited, but preferably includes an amine salt, a pyridium salt, and a quaternary ammonium salt.
  • amine salt-based cationic surfactants include laurylamine hydrochloride, stearylamine hydrochloride, oleylamine acetate, stearylamine acetate, stearylaminopropylamine acetate, and the like.
  • Examples of the pyridinium salt-based cationic surfactant include lauryl pyridinium chloride, myristyl pyridin-dum chloride, cetyl pyridin-dum chloride and the like.
  • Examples of the quaternary ammo-pum salt cationic surfactant include alkyl dimethyl benzylammonium-pum chloride, lauryltrimethylammo-pumchloride, cetyltrimethylammonium-pumchloride, stearyltrimethylammonium-pumchloride, dilauryldimethylammonium-pumchloride, Dioleyldimethylammonium chloride, dicocoyldimethylammonium chloride, distearyldimethylammonium chloride, lauryldihydroxyethylmethylammonium chloride, oleylbispolyoxyethylenemethylammonium chloride, stearylhydroxyethyldimethylammonium chloride Peryldimethylbenzylammonium -Phamchloride, lauroylaminopropyldimethylethylammonium Arm ethosulfate, lauroyl ⁇ amino propyl dimethyl
  • Particularly preferred cationic surfactants are those which gel or swell in water, for example, dialkyldimethylammonium-dimethyl chlorides whose alkyl moiety is C8-C22, Among them, dilauryl dimethylammonium-pum chloride, Dioleyldimethylammonium chloride, dicocoyldimethylammonium chloride and distearyldimethylammonium chloride. These surfactants may be used alone or in combination of two or more.
  • the basic substance used in the present invention is not particularly limited, but preferably has a pH of 7.5 or more, especially 9 to 12 when a 1% by mass aqueous solution or 1% by mass aqueous suspension is used. Some are preferred. Examples of such compounds include hydroxides of alkali metals and alkaline earth metals, alkali metal salts and alkaline earth metal salts, and compounds and minerals containing the same. More specifically, sodium hydroxide, potassium hydroxide, sodium hydrogencarbonate, sodium carbonate, calcium hydroxide, calcium carbonate, calcium oxide, basic white carbon, basic acid clay and the like can be mentioned. Particularly preferred are sodium hydrogen carbonate, sodium carbonate, calcium hydroxide, calcium carbonate, basic white carbon and basic acid clay. These basic substances may be used alone, or two or more kinds may be used in combination.
  • the surfactant used in the present invention is not particularly limited, and examples thereof include polyoxyalkylene glycol higher fatty acid ester, polyoxyalkylene alkyl ether, polyoxyalkylene alkylaryl ether, polyoxyalkylene alkylaryl ether, Non-ionic surfactants such as sorbitan monoalkylate, acetylene glycol, polyoxyethylene acetylene glycol, alkylaryl sulfonates, dialkyl sulfonates, alkyl sulfates, alkyl phosphates, alkyl aryl phosphates , Alkyl aryl phosphate, polyoxyalkylene alkyl ether sulfate, naphthalene sulfonate and its condensate, alkyl naphthalene sulfonate and its condensate, rig- Polycarboxylic acid-type polymer interfaces such as sulfonic acid salt, acrylic acid itaconic acid cop
  • the inorganic substance is not particularly limited as long as it is a substance, and examples of the inorganic substance include an inorganic hollow body such as a glassy hollow body, expanded pearlite, expanded fly ash, vermiculite, calcined vermiculite, shirasu balloon, microballoon, and cenosphere.
  • examples of the organic substances include plastic hollow bodies, waxes, solid paraffins, foam-containing starch, cork, wood chips, plant pieces such as cotton bean, polybutenes and other specific light substances, and organic solvents.
  • an inorganic hollow body such as a glassy hollow body and a heated Shirasu foam
  • a plastic hollow body such as a Shiridani vinylidene.acrylonitrile copolymer plastic balloon and an acrylonitrile-based plastic balloon are preferable. These may be used alone, or
  • Two or more types may be used in combination.
  • the homogeneously diffusible granular pesticide preparation of the present invention can contain, as necessary, an additive component usually used in pesticide preparations.
  • an additive component usually used in pesticide preparations.
  • additional components extenders, auxiliary components, and the like are used.
  • a solid carrier such as a mineral carrier, a water-soluble salt, or the like is used.
  • a mineral carrier such as a mineral carrier, a water-soluble salt, or the like.
  • Specific examples include clays, calcium carbonate, bentonite, talc, diatomaceous earth, acid clay, silica sand, and granular carbonate.
  • examples include calcium, granular diatomaceous earth, calcium stearate, white carbon, potassium chloride, anhydrous sodium sulfate, potassium sulfate, urea, ammonium sulfate, and sodium benzoate. These may be used alone or in combination of two or more.
  • auxiliary component for example, a binder for preparing a granular composition, specifically, carboxymethylcellulose sodium salt, dextrin, water-soluble starch, xanthan gum, guar gum, sucrose, polybutylpyrrolidone, polybutyl alcohol , Sodium polyacrylate, polyethylene glycol having an average molecular weight of 6000 to 20000, and polyethylene oxide having an average molecular weight of 100,000 to 5,000,000.
  • a binder for preparing a granular composition specifically, carboxymethylcellulose sodium salt, dextrin, water-soluble starch, xanthan gum, guar gum, sucrose, polybutylpyrrolidone, polybutyl alcohol , Sodium polyacrylate, polyethylene glycol having an average molecular weight of 6000 to 20000, and polyethylene oxide having an average molecular weight of 100,000 to 5,000,000.
  • Organic solvents used for dissolving the acidic pesticide active ingredient and the cationic surfactant and adsorbing them on the carrier specifically, alkylnaphthalene, dimethylformamide, dimethylsulfoxide, N-methyl-2-pyrrolidone, N- Octylpyrrolidone, polyhydric alcohol, silicone oil and the like.
  • a stabilizer or the like may be used. These may be used alone or in combination of two or more.
  • the composition ratio of the non-disintegrable pesticide granules is usually 0.1 to 40% by mass of an acidic pesticide active ingredient, and 140 to 100% by mass of a cationic surfactant.
  • the basic substance is selected in the range of 0.1 to 95% by mass, and the pH of a 1% by mass aqueous suspension of the non-disintegrating pesticide granules is usually 5 or more, preferably 7 or more, more preferably 7. Adjusted to be 5—11.5.
  • the composition ratio of the homogeneously diffusible granular pesticide preparation of the present invention is usually 1 to 70% by mass of non-disintegrable pesticide granules, 0 to 50% by mass of pesticidal active ingredient, and surface activity. 0.1 to 30% by mass, floating component 0.1 to 50% by mass, extender 0 to 95% by mass, preferably 5 to 70% by mass, auxiliary component 0 to 50% by mass, preferably 0.1 to 30% %, More preferably one having a specific gravity of less than 1 and sufficient for floating on the water surface.
  • the uniformly dispersible granular pesticide preparation of the present invention disintegrates within 30 minutes after being treated in the field, and gradually disperses the non-disintegrable pesticide granules contained therein into the field during the disintegration.
  • This is a labor-saving controlled-release pesticide formulation that has been settled down and has a slow release of the pesticide active ingredient contained in the pesticide granule.
  • It is also possible to design a dissolution property suitable for each pesticide active ingredient by including a non-disintegrable pesticide granular material in a homogeneously diffusible granular pesticide formulation.
  • the present invention also relates to the homogeneously diffusible granular pesticide formulation and a homogeneously diffusible granular pesticide formulation having neither a cationic surfactant nor a basic substance in a ratio of 1: 9-9: 1. It also includes mixed pesticide preparations mixed by mass ratio.
  • the size itself is usually in the form of a sphere, usually having a particle diameter of 11 to 20 mm, preferably 3 to 10 mm, and in the case of a horizontally long shape, usually having a minor diameter of 1 to 20 mm, preferably.
  • the size of non-disintegrable pesticide granules contained in this pesticide formulation is usually 3 to 10 mm, major axis is 3 to 40 mm, and preferably 5 to 30 mm.
  • 0.1 to 3 mm preferably 0.1 to 10 mm, preferably 0.5 to 7 mm, preferably 0.5 to 7 mm, major axis 0.3 to 30 mm, preferably 1.5 to 20 mm for a horizontally long shape.
  • the method for preparing the homogeneously diffusible granular pesticide preparation of the present invention is preferably a non-disintegrable pesticidal granule which contains an acidic pesticide active ingredient, a cationic surfactant and a basic substance and does not disintegrate in water within 30 minutes.
  • a method of subjecting the product to a granulation treatment together with a surfactant and a buoyant component to obtain a spherical shape having a particle diameter of 120 mm or a horizontally long shape having a minor axis of 120 mm and a major axis of 3 to 40 mm can be mentioned.
  • a step of preparing a powdery granular material by adding an acidic agricultural chemical active ingredient, a cationic surfactant and a basic substance together with auxiliary components such as a binder and a bulking agent to a tumbling granulator A step of preparing a granular composition having a target particle size and grain length by gradually adding an appropriate amount of water or an aqueous solution in which a binder is dissolved to the granular material, and, if necessary, applying a film to the surface of the granular composition. It consists of coating the forming substance, drying and then sieving.
  • an acidic pesticide active ingredient, a cationic surfactant, and a basic substance are pulverized with an air mill or mechanochemical pulverized together with auxiliary ingredients such as a binder and a bulking agent to prepare a powdery raw material.
  • auxiliary ingredients such as a binder and a bulking agent.
  • the mixture is adjusted to have the target particle size and grain length. Extruding and granulating from a screen with a set aperture diameter to prepare a granular composition, and coating the granular composition with a film-forming substance on its surface, if necessary, drying, and sieving. Power.
  • an acidic pesticide active ingredient, a basic substance, and auxiliary ingredients such as a cationic surfactant and a bulking agent used as needed are pulverized by an air mill or mechanochemical to prepare a powdery raw material.
  • oil-absorbing granules having the target particle size and target length are put into a conical screw-type mixer, and auxiliary components such as a cationic surfactant diluted with a solvent and a binder used as necessary are sprayed simultaneously.
  • the oil-absorbing granular material obtained by mixing while mixing is coated with the powdery raw material obtained in the previous step, and the process of preparing the granular composition and drying the granular composition as necessary, and then sieving. Become. (Manufacture of granular pesticide formulations)
  • the non-disintegrable pesticide granules, surfactants, and floating components obtained by the above-mentioned production method are combined with auxiliary components such as extenders, binders, stabilizers, and the like, which are used as necessary.
  • the mixture is kneaded with an appropriate amount of water using an extrusion granulator or the like, and the resulting mixture is subjected to particle size and particle size of non-disintegrable pesticide granules.
  • a step of preparing a granular composition by extruding and granulating a screen having a larger opening diameter, and coating the granular composition with a film-forming substance on its surface, if necessary, and drying it.
  • the sieving process power is also increased.
  • the non-disintegrable pesticide granules, surfactants and floating components obtained by the above-mentioned production method are mixed with auxiliary components such as a bulking agent, a binder and a stabilizer, which are used as necessary.
  • auxiliary components such as a bulking agent, a binder and a stabilizer, which are used as necessary.
  • a process of preparing a granular material by placing it in a tumbling granulator together with the pesticidal active ingredient, and gradually adding an aqueous solution in which an appropriate amount of water or a binder is dissolved to the granular material, and a granular composition having a target particle size and particle length.
  • the drying treatment is preferably performed by an appropriate drying device such as a fluidized bed drying device or a vacuum drying device.
  • a herbicide such as a herbicide composed of a sulfonylprea compound, particularly a compound represented by the general formula (I)
  • a cationic surfactant which is a gel that gels in water or has a swelling property.
  • a part represents a mass part.
  • the pesticidal active ingredient used in the Examples had a deviation of pKa2-7, and the basic substance was a 1% by mass aqueous solution or a 1% by mass aqueous suspension having a pH of 7.5 or more.
  • Each of the non-disintegrable pesticide granules was a 1% by mass aqueous suspension having a pH of 5 or more.
  • the cationic surfactants used in Examples 1, 7, 9 and 10 were all capable of gelling in water.
  • the mixture obtained by uniformly mixing 25 ⁇ was pulverized with an impact pulverizer.
  • the obtained powder is kneaded by adding an appropriate amount of water in a high-speed stirrer, and then extruded using a dome-type granulator through a screen having an aperture of 0.5 mm, and the granulated material is statically held at 60 ° C.
  • pesticide granules containing 6.25% by mass of bensulfuron-methyl and having a diameter of 0.4-0.6 mm and a length of 16 mm were obtained.
  • the obtained pesticide granules were dropped into water, and after 30 minutes, the disintegration state of the particles was observed. As a result, no disintegrated particles were observed, and the particles were determined to be non-disintegrated.
  • pesticide granules containing 6.25% by mass of bensulfuron-methyl and having a diameter of 0.4 to 0.6 mm and a length of 16 mm were obtained.
  • the obtained pesticide granules were dropped into water, and after 30 minutes, the disintegration state of the particles was observed. As a result, no disintegrated particles were observed, and it was determined that the particles were not disintegrated.
  • Compound A of the general formula (I) in which R 1 is an ethyl group (hereinafter referred to as Compound A.
  • P Ka 6.17) 10 parts and basic white carbon 1.7 parts are uniformly mixed and pulverized with an air mill. A contained powder was prepared.
  • the product After extrusion granulation and sizing to the target size, the product is dried at a product temperature of 60 ° C with a fluid bed dryer and sieved to obtain a compound with a diameter of 3-7 mm and a length of 3-20 mm.
  • a particulate matter containing 3% by mass of the substance A was obtained as a uniform diffusible granular pesticide preparation.
  • the obtained homogeneously diffusible granular pesticide formulation was dropped into water and observed. As a result, the particles of the formulation were disintegrated within 30 minutes, and the non-disintegrated pesticide granules settled out.
  • the obtained mixture is extruded and granulated from a screen with an opening diameter of 5 mm using a basket type granulator, and sized to the target size, and then a fluidized bed dryer at a product temperature of 60 ° C.
  • a granular material containing 3% by mass of the compound A having a diameter of 3 to 7 mm and a length of 3 to 20 mm was obtained as a uniform diffusible granular pesticide preparation.
  • the obtained homogeneously diffusible granular pesticide formulation was dropped into water and observed. As a result, the particles of the formulation were disintegrated within 30 minutes, and the non-disintegrated pesticide granules settled out.
  • R 1 is a methoxymethyl group (hereinafter, referred to as compound B. P Ka5.7.5) 10 parts, distearyl dimethylammonium chloride 6.7 parts, dilauryldimethylammonium chloride 6 7 parts, calcium carbonate 63.2 parts, polybutyl alcohol 6.7 parts,
  • the mixture obtained by uniformly mixing 6.7 parts of arsenic starch was pulverized with an impact pulverizer.
  • a mixture obtained by adding an appropriate amount of water to the obtained powder is kneaded with a high-speed stirrer, and then extruded using a dome-type granulator through a screen having an opening diameter of 0.5 mm, and the granulated material is heated at 60 ° C.
  • a granular material containing 3% by mass of compound B having a diameter of 3 to 7 mm and a length of 3 to 20 mm was obtained as a uniform diffusible granular pesticide formulation.
  • the obtained homogeneously diffusible granular pesticide product was dropped into water and observed.
  • the particles of the formulation were disintegrated within 30 minutes, and the non-disintegrated pesticide granules settled out.
  • the obtained pesticide granules were dropped into water, and after 30 minutes, the disintegration state of the particles was observed. As a result, no disintegrated particles were observed, and the particles were determined to be non-disintegrated.
  • the mixture is extruded and granulated through a screen with a mesh size of 5 mm using an extrusion granulator, sized to the target size, and dried at 60 ° C in a fluidized bed dryer.
  • a granular material containing 3% by mass of compound B and 3% by mass of fentrazamide having a diameter of 3 to 7 mm and a length of 3 to 20 mm was obtained as a homogeneously diffusible granular pesticide formulation.
  • the obtained homogeneously diffusible granular pesticide formulation was dropped into water and observed. As a result, the particles of the formulation were disintegrated within 30 minutes, and the non-disintegrated pesticide granules settled out.
  • Birazosulfronethyl (pKa 3.91) 6. 25 parts, cetyltrimethylammonium chloride 6. Canoresium carbonate 68. Posivininoleanolecone olecole 18. Mix uniformly mixed 75. And crushed. The obtained powder is kneaded by kneading an appropriate amount of water in a high-speed stirrer, and then extruded using a dome-type granulator through a screen with an aperture of 0.5 mm, and the granulated material is cooled at 60 ° C.
  • pesticide granules containing 6.25% by mass of birazosulfronethyl and having a diameter of 0.4 to 0.6 mm and a length of 16 mm were obtained.
  • the pesticide granules were dropped into water, and after 30 minutes, the disintegration state of the particles was observed. No disintegrated particles were observed, and the particles were judged to be non-disintegrated.
  • Example 1 16 parts of the non-disintegrating pesticide granules, 5 parts of sodium salt of butyl naphthalenesulfonic acid formalin condensate, 1 part of polyoxyethylene acetylene glycol, 0.5 part of sodium polyacrylate, Example 1 A mixture of 14 parts of the plastic hollow body used in the above, 20 parts of anhydrous sodium sulfate, and 55.4 parts of urea and an appropriate amount of water was kneaded in a high-speed stirrer, and then a 5 mm screen with an extrusion granulator was used.
  • the obtained powder is kneaded by adding an appropriate amount of water in a high-speed stirrer, and then extruded using a dome-type granulator through a screen having an aperture of 0.7 mm, and the granulated material is heated at 60 ° C. After standing and drying, pesticide granules containing 20% by mass of tricyclazole and having a diameter of 0.6 to 0.8 mm and a length of 2 to 9 mm were obtained.
  • the obtained pesticide granules were dropped into water, and after 30 minutes, the disintegration state of the particles was observed, and no disintegrated particles were observed.
  • 40 parts of the non-disintegrating pesticide granules 5 parts of sodium salt of butyl naphthalenesulfonic acid formalin condensate, 1 part of polyoxyethylene acetylene glycol, 0.5 part of sodium polyacrylate, and a plastic hollow body Acrylonitrile plastic balloon [Matsumoto Microsphere F-80E (trade name), manufactured by Matsumoto Yushi Seiyaku Co., Ltd.] 14 parts, anhydrous sodium sulfate 20 parts, urea 31.4 parts, and a mixture obtained by adding an appropriate amount of water After kneading with a high-speed stirrer, the mixture is extruded and granulated through a screen with an opening diameter of 5 mm using an extrusion granulator, and sized to the target size.
  • a granule having a diameter of 3 to 7 mm and a length of 3 to 20 mm and containing 8% by mass of tricyclazole was obtained as a uniform diffusible granular pesticide formulation.
  • the obtained homogeneously diffusible granular pesticide formulation was dropped into water and observed. As a result, the particles of the formulation were disintegrated within 30 minutes, and the non-disintegrated pesticide granules settled out.
  • a mixture obtained by adding an appropriate amount of water to the obtained powder is kneaded with a high-speed stirrer, and then extruded and granulated from a screen having an opening diameter of 0.7 mm using a dome-type granulator.
  • the obtained pesticide granules were dropped into water, and after 30 minutes, the collapse state of the particles was observed. As a result, no disintegrated particles were observed, and the particles were judged to be non-disintegrated.
  • Example 9 A mixture of 14 parts of the plastic hollow body, 20 parts of anhydrous sodium sulfate, and 31.4 parts of urea to which an appropriate amount of water was added was kneaded with a high-speed stirrer, and the mixture was extruded through a 5 mm screen with an extrusion granulator.
  • a mixture obtained by uniformly mixing 6.25 parts of bensulfuron-methyl (pKa5.03), 81.25 parts of calcium carbonate, 6.25 parts of polybutyl alcohol, and 6.25 parts of pregelatinized starch was pulverized with an impact mill.
  • a mixture obtained by adding an appropriate amount of water to the obtained powder is kneaded with a high-speed stirrer, and then extruded using a dome-type granulator through a screen having an opening diameter of 0.5 mm, and granulated at 60 ° C.
  • a pesticide granule containing 6.25% by mass of bensulfuron-methyl and having a diameter of 0.4 to 0.6 mm and a length of 16 mm The obtained pesticide granules were dropped into water, and after 30 minutes, the disintegration state of the particles was observed. As a result, no disintegrated particles were observed, and the particles were judged to be non-disintegrated.
  • the product was obtained as a homogeneously diffusing granular pesticide formulation.
  • the obtained homogeneously diffusible granular pesticide formulation was dropped into water and observed. As a result, the particles of the formulation were disintegrated within 30 minutes, and the non-collapsible pesticide particulates settled out.
  • Compound A (pKa 6.17) (10 parts) and basic white carbon (1.7 parts) were uniformly mixed and pulverized with an air mill to prepare a compound A-containing powder.
  • the pesticide granules were dropped into water, and after 30 minutes, the disintegration state of the particles was observed. As a result, no disintegrated particles were observed, and the particles were judged to be non-disintegrated.
  • 30 parts of the non-disintegrable pesticide granules 3 parts of sodium dibutylnaphthalenesulfonate, 2 parts of lauryl sulfate, 3 parts of polyoxyethylene acetylene glycol, 2 parts of enzyme-modified dextrin, 1 part of sodium polyacrylate Parts, 2 parts of white carbon, 14 parts of the plastic hollow body used in Example 1, 20 parts of anhydrous sodium sulfate, and 34.9 parts of urea, and a mixture obtained by adding an appropriate amount of water to the mixture.
  • Compound B (pKa 5.75) 10 parts, distearyl dimethylammonium chloride 6.7 parts, dilauryldimethylammonium chloride 6.7 parts, clay 63.2 parts, polybutyl alcohol 6.7 parts, pregelatinized starch 6.
  • the mixture obtained by uniformly mixing 7 parts was pulverized with an impact pulverizer.
  • a mixture obtained by adding an appropriate amount of water to the obtained powder is kneaded with a high-speed stirrer, and then extruded and granulated through a screen having an opening diameter of 0.5 mm using a dome-type granulator.
  • pesticide granules containing 6.25% by mass of birazosulfronethyl and having a diameter of 0.4 to 0.6 mm and a length of 16 mm were obtained.
  • the obtained pesticide granules were dropped into water, and after 30 minutes, the disintegration state of the particles was observed. As a result, no disintegrated particles were observed, and it was determined that the particles were not disintegrated.
  • Example 1 16 parts of the non-disintegrable pesticide granules, 5 parts of sodium salt of butyl naphthalenesulfonic acid formalin condensate, 1 part of polyoxyethylene acetylene glycol, 0.5 part of sodium polyacrylate, Example 1 A mixture of 14 parts of the plastic hollow body used in the above, 20 parts of anhydrous sodium sulfate, and 55.4 parts of urea and an appropriate amount of water was kneaded with a high-speed stirrer, and then extruded using a granulator with a screen having an aperture of 5 mm.
  • the product After extrusion granulation and sizing to the target size, the product is dried at 60 ° C in a fluidized bed drier and sieved to obtain virazos with a diameter of 3-7 mm and a length of 3-20 mm.
  • the granules containing Rufuronechiru 1 mass 0/0 was obtained as a uniform one diffusible granular pesticide formulations.
  • the obtained homogeneously diffusible granular pesticide formulation was dropped into water and observed. As a result, the particles of the formulation were disintegrated within 30 minutes, and the non-disintegrated pesticide granules settled out.
  • the homogeneously diffusible granular pesticide preparation of Example 17 is characterized in that the pesticidal active ingredient is a herbicide sulfolureurea-based compound or difluoromethanesulfo-lua-lide derivative or a salt thereof.
  • the dissolution rate in water was lower than that in Comparative Example 13 in the test from 1 day to 35 days after the treatment, indicating that the drug was controlled to be released gradually.
  • Example 8 has a lower concentration in water than the former, and the elution of the pesticidal active ingredient is only a small portion at the initial stage and does not continue. Many of the pesticidal active ingredients in the uniform diffusible granular pesticide formulation remain unused! /, Clearly inferior.
  • Example 5 and Comparative Example 3 when Example 5 and Comparative Example 3 are compared, the latter has a higher water concentration than the former, and the sustained release of the pesticide active ingredient is reduced due to the absence of a basic substance. You can see.
  • Example 5 From the two windward sides of a paddy field having a short side of 20 m, a long side of 50 m, and a water depth of 5 cm shown in FIG. 1, the uniformly diffusible granular pesticide preparation of Example 5 was sprayed by hand. Forty-eight hours after spraying, water is collected from point (A-L) shown in Fig. 1 and analyzed. Was calculated, and the standard deviation of the concentration in water at each point was divided by the average to calculate the fluctuation rate. The results are shown in Table 2.
  • the homogeneously diffusible granular pesticidal preparation of the present invention can be prepared by a simple method, and moderately releases the dissolution of the pesticidal active ingredient, whereby the efficacy of the pesticidal active ingredient can be maintained for a long period of time.
  • Spray a granular pesticide formulation that can exert its effect and reduce the environmental burden by reducing the release of pesticide active ingredients into the environment, and reduce or prevent harm caused by the pesticide active ingredients, for example, harm to target crops.
  • the method enables uniform diffusion throughout the paddy field, and has a remarkable effect of contributing to labor saving in agricultural work.

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  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Toxicology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
PCT/JP2004/013776 2003-09-26 2004-09-22 均一拡散性粒状農薬製剤 WO2005029956A1 (ja)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012077961A2 (ko) * 2010-12-06 2012-06-14 신젠타 파티서페이션즈 아게 수면 부유 확산성 농약 정제 제형
WO2013050433A1 (en) 2011-10-05 2013-04-11 Bayer Intellectual Property Gmbh Pesticide preparation and process for producing the same
WO2015159906A1 (ja) * 2014-04-18 2015-10-22 クミアイ化学工業株式会社 水面浮遊性大型農薬粒状組成物およびその製造方法
EP3238540A1 (en) * 2016-04-28 2017-11-01 Bayer CropScience Aktiengesellschaft Timed-release-type granular agrochemical composition and method for manufacturing same

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130053247A1 (en) * 2011-08-25 2013-02-28 Dow Agrosciences Llc Increasing particle size of pesticides to reduce movement in soil
CN104782620B (zh) * 2013-02-22 2018-04-27 住友化学株式会社 水面漂浮性颗粒杀虫剂，和含有它的袋装农用化学制剂
CN115191436B (zh) * 2022-09-19 2022-11-22 山东省寿光蔬菜产业集团有限公司 一种害虫引诱剂组合物及其制备方法

Citations (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6322502A (ja) * 1986-07-14 1988-01-30 Kao Corp 粒状農薬の製造方法
JPH0466509A (ja) * 1990-06-29 1992-03-02 Nissan Chem Ind Ltd 水田除草用粒剤
JPH04273802A (ja) * 1991-02-28 1992-09-30 Nippon Soda Co Ltd 錠剤様発泡性農薬組成物の製造法
JPH05155715A (ja) * 1991-12-04 1993-06-22 Sumitomo Chem Co Ltd 農薬製剤
JPH06505256A (ja) * 1991-01-24 1994-06-16 モンサント・カンパニー 改良されたグリホセート処方物
JPH06263601A (ja) * 1993-03-11 1994-09-20 Nippon Bayeragrochem Kk 農薬用粒剤
JPH10109904A (ja) * 1996-10-04 1998-04-28 Sankyo Co Ltd 水田用除草粒剤
JPH10109903A (ja) * 1996-10-04 1998-04-28 Sankyo Co Ltd 水田用除草粒剤
JP2000302602A (ja) * 1999-04-23 2000-10-31 Kumiai Chem Ind Co Ltd 水面浮遊性粒状農薬製剤、その製造方法およびその散布方法
JP2000319103A (ja) * 1999-05-13 2000-11-21 Kumiai Chem Ind Co Ltd 水面浮遊性粒状農薬製剤及びその製造法
JP2001302576A (ja) * 2000-04-14 2001-10-31 Rikogaku Shinkokai 界面活性剤との結晶化を利用した芳香族化合物の気化速度を調節する方法
JP2002179507A (ja) * 2000-10-05 2002-06-26 Kumiai Chem Ind Co Ltd 均一拡散性粒状農薬製剤およびその散布方法
JP2003040702A (ja) * 2001-07-24 2003-02-13 Kumiai Chem Ind Co Ltd 農薬粒状組成物の散布方法および粒状農薬合剤
WO2003082008A1 (fr) * 2002-03-29 2003-10-09 Kumiai Chemical Industry Co., Ltd. Composition agrochimique granulaire
JP2004002260A (ja) * 2002-03-22 2004-01-08 Bayer Cropscience Kk 改良農薬組成物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2931869B2 (ja) * 1994-11-17 1999-08-09 北興化学工業株式会社 粒状農薬水和剤

Patent Citations (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6322502A (ja) * 1986-07-14 1988-01-30 Kao Corp 粒状農薬の製造方法
JPH0466509A (ja) * 1990-06-29 1992-03-02 Nissan Chem Ind Ltd 水田除草用粒剤
JPH06505256A (ja) * 1991-01-24 1994-06-16 モンサント・カンパニー 改良されたグリホセート処方物
JPH04273802A (ja) * 1991-02-28 1992-09-30 Nippon Soda Co Ltd 錠剤様発泡性農薬組成物の製造法
JPH05155715A (ja) * 1991-12-04 1993-06-22 Sumitomo Chem Co Ltd 農薬製剤
JPH06263601A (ja) * 1993-03-11 1994-09-20 Nippon Bayeragrochem Kk 農薬用粒剤
JPH10109904A (ja) * 1996-10-04 1998-04-28 Sankyo Co Ltd 水田用除草粒剤
JPH10109903A (ja) * 1996-10-04 1998-04-28 Sankyo Co Ltd 水田用除草粒剤
JP2000302602A (ja) * 1999-04-23 2000-10-31 Kumiai Chem Ind Co Ltd 水面浮遊性粒状農薬製剤、その製造方法およびその散布方法
JP2000319103A (ja) * 1999-05-13 2000-11-21 Kumiai Chem Ind Co Ltd 水面浮遊性粒状農薬製剤及びその製造法
JP2001302576A (ja) * 2000-04-14 2001-10-31 Rikogaku Shinkokai 界面活性剤との結晶化を利用した芳香族化合物の気化速度を調節する方法
JP2002179507A (ja) * 2000-10-05 2002-06-26 Kumiai Chem Ind Co Ltd 均一拡散性粒状農薬製剤およびその散布方法
JP2003040702A (ja) * 2001-07-24 2003-02-13 Kumiai Chem Ind Co Ltd 農薬粒状組成物の散布方法および粒状農薬合剤
JP2004002260A (ja) * 2002-03-22 2004-01-08 Bayer Cropscience Kk 改良農薬組成物
WO2003082008A1 (fr) * 2002-03-29 2003-10-09 Kumiai Chemical Industry Co., Ltd. Composition agrochimique granulaire

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012077961A2 (ko) * 2010-12-06 2012-06-14 신젠타 파티서페이션즈 아게 수면 부유 확산성 농약 정제 제형
WO2012077961A3 (ko) * 2010-12-06 2012-10-04 신젠타 파티서페이션즈 아게 수면 부유 확산성 농약 정제 제형
WO2013050433A1 (en) 2011-10-05 2013-04-11 Bayer Intellectual Property Gmbh Pesticide preparation and process for producing the same
US9204639B2 (en) 2011-10-05 2015-12-08 Bayer Intellectual Property Gmbh Pesticide preparation and process for producing the same
WO2015159906A1 (ja) * 2014-04-18 2015-10-22 クミアイ化学工業株式会社 水面浮遊性大型農薬粒状組成物およびその製造方法
EP3238540A1 (en) * 2016-04-28 2017-11-01 Bayer CropScience Aktiengesellschaft Timed-release-type granular agrochemical composition and method for manufacturing same
WO2017186577A1 (en) 2016-04-28 2017-11-02 Bayer Cropscience Aktiengesselschaft Timed-release-type granular agrochemical composition and method for manufacturing same
JP2019515928A (ja) * 2016-04-28 2019-06-13 バイエル・クロップサイエンス・アクチェンゲゼルシャフト 徐放型顆粒状農薬組成物およびその製造方法
JP7204486B2 (ja) 2016-04-28 2023-01-16 バイエル・クロップサイエンス・アクチェンゲゼルシャフト 徐放型顆粒状農薬組成物およびその製造方法

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CN1856247B (zh) 2010-05-05
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KR20060063914A (ko) 2006-06-12
CN1856247A (zh) 2006-11-01

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